Expert Opinion on Drug Discovery, Volume 13, Issue 1 (2018)

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Expert Opinion on Drug Discovery, Volume 13, Issue 1 (2018)

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Editorial

Editorial
Advances in omics for informed pharmaceutical research and development in the era of systems medicine
Jane P. F. Bai, Ioannis N. Melas, Junguk Hur & Ellen Guo
Pages: 1-4
Published online: 27 Oct 2017
First Page PreviewforAdvances in omics for informed pharmaceutical research and development in the era of systems medicine | Full Text | References | PDF (414.5 KB)
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Review

Review
Mathematical modeling of efficacy and safety for anticancer drugs clinical development
Silvia Maria Lavezzi, Elisa Borella, Letizia Carrara, Giuseppe De Nicolao, Paolo Magni & Italo Poggesi
Pages: 5-21
Published online: 12 Oct 2017
AbstractforMathematical modeling of efficacy and safety for anticancer drugs clinical development | Full Text | References | PDF (1.7 MB)
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Review
Molecular dynamics simulations and novel drug discovery
Xuewei Liu, Danfeng Shi, Shuangyan Zhou, Hongli Liu, Huanxiang Liu & Xiaojun Yao
Pages: 23-37
Published online: 15 Nov 2017
AbstractforMolecular dynamics simulations and novel drug discovery | Full Text | References | PDF (1.4 MB)
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Review
Recent developments concerning the application of the Mannich reaction for drug design
Bernhard Biersack, Khursheed Ahmed, Subhash Padhye & Rainer Schobert
Pages: 39-49
Published online: 14 Nov 2017
AbstractforRecent developments concerning the application of the Mannich reaction for drug design | Full Text | References | PDF (951.7 KB)
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Review
New approaches for identifying and testing potential new anti-asthma agents
Amelia Licari, Riccardo Castagnoli, Ilaria Brambilla, Alessia Marseglia, Maria Angela Tosca, Gian Luigi Marseglia & Giorgio Ciprandi
Pages: 51-63
Published online: 31 Oct 2017
AbstractforNew approaches for identifying and testing potential new anti-asthma agents | Full Text | References | PDF (1.4 MB)
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Review
Novel avenues for drug discovery in diabetic kidney disease
Matthew D. Breyer & Matthias Kretzler
Pages: 65-74
Published online: 16 Nov 2017
AbstractforNovel avenues for drug discovery in diabetic kidney disease | Full Text | References | PDF (959.4 KB)
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Review
Recent opportunities in matrix metalloproteinase inhibitor drug design for cancer
Yue Zhong, Yu-Ting Lu, Ying Sun, Zhi-Hao Shi, Nian-Guang Li, Yu-Ping Tang & Jin-Ao Duan
Pages: 75-87
Published online: 31 Oct 2017
AbstractforRecent opportunities in matrix metalloproteinase inhibitor drug design for cancer | Full Text | References | PDF (1.5 MB)
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Review
The application of molecular topology for ulcerative colitis drug discovery
Carolina L. Bellera, Mauricio E. Di Ianni & Alan Talevi
Pages: 89-101
Published online: 01 Nov 2017
AbstractforThe application of molecular topology for ulcerative colitis drug discovery | Full Text | References | PDF (1.5 MB)
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Drug Discovery Case History

Article
Pimavanserin: novel pharmacotherapy for Parkinson’s disease psychosis
Zeyad T. Sahli & Frank I. Tarazi
Pages: 103-110
Published online: 31 Oct 2017
AbstractforPimavanserin: novel pharmacotherapy for Parkinson’s disease psychosis | Full Text | References | PDF (655.8 KB)
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Corrigendum

Correction
Corrigendum
Page: 111
Published online: 09 Nov 2017
CitationforCorrigendum | Full Text | PDF (101 KB)
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