Expert Opinion on Drug Discovery, Volume 14, Issue 11 (2019)

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Expert Opinion on Drug Discovery, Volume 14, Issue 11 (2019)

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Editorial

Editorial
Transforming cancer drug discovery with Big Data and AI
Paul Workman, Albert A. Antolin & Bissan Al-Lazikani
Pages: 1089-1095
Published online: 08 Jul 2019
First Page PreviewforTransforming cancer drug discovery with Big Data and AI | Full Text | References | PDF (1.3 MB) | EPUB
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Special Report

Report
Developments with bead-based screening for novel drug discovery
Dehua Pei & George Appiah Kubi
Pages: 1097-1102
Published online: 23 Jul 2019
AbstractforDevelopments with bead-based screening for novel drug discovery | Full Text | References | PDF (516.8 KB) | EPUB
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Perspective

Article
How can monoclonal antibodies be harnessed against neglected tropical diseases and other infectious diseases?
Andreas H. Laustsen
Pages: 1103-1112
Published online: 31 Jul 2019
AbstractforHow can monoclonal antibodies be harnessed against neglected tropical diseases and other infectious diseases? | Full Text | References | PDF (1.2 MB) | EPUB
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Review

Review
What human blood-brain barrier models can tell us about BBB function and drug discovery?
Lino Ferreira
Pages: 1113-1123
Published online: 06 Aug 2019
AbstractforWhat human blood-brain barrier models can tell us about BBB function and drug discovery? | Full Text | References | PDF (1.3 MB) | EPUB
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Review
Advances with weak affinity chromatography for fragment screening
Fotios Tsopelas & Anna Tsantili-Kakoulidou
Pages: 1125-1135
Published online: 05 Aug 2019
AbstractforAdvances with weak affinity chromatography for fragment screening | Full Text | References | PDF (1 MB) | EPUB
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Review
An overview of late-stage functionalization in today’s drug discovery
Michael Moir, Jonathan J. Danon, Tristan A. Reekie & Michael Kassiou
Pages: 1137-1149
Published online: 14 Aug 2019
AbstractforAn overview of late-stage functionalization in today’s drug discovery | Full Text | References | PDF (2.2 MB) | EPUB
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Review
Novel approaches to anti-obesity drug discovery with gut hormones over the past 10 years
Frances Rose, Stephen Bloom & Tricia Tan
Pages: 1151-1159
Published online: 29 Jul 2019
AbstractforNovel approaches to anti-obesity drug discovery with gut hormones over the past 10 years | Full Text | References | PDF (836.5 KB) | EPUB
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Review
Advances in preclinical approaches to Chagas disease drug discovery
Fernando Villalta & Girish Rachakonda
Pages: 1161-1174
Published online: 14 Aug 2019
AbstractforAdvances in preclinical approaches to Chagas disease drug discovery | Full Text | References | PDF (1.8 MB) | EPUB
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Open Access
Review
Advances in the structural annotation of human carbonic anhydrases and impact on future drug discovery
Alessio Nocentini & Claudiu T. Supuran
Pages: 1175-1197
Published online: 22 Aug 2019
AbstractforAdvances in the structural annotation of human carbonic anhydrases and impact on future drug discovery | Full Text | References | PDF (3 MB) | EPUB
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Drug Discovery Case History

Article
Preclinical discovery and development of fingolimod for the treatment of multiple sclerosis
Claudia Volpi, Ciriana Orabona, Antonio Macchiarulo, Roberta Bianchi, Paolo Puccetti & Ursula Grohmann
Pages: 1199-1212
Published online: 07 Aug 2019
AbstractforPreclinical discovery and development of fingolimod for the treatment of multiple sclerosis | Full Text | References | PDF (1.3 MB) | EPUB
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Open Access

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