Expert Opinion on Drug Discovery, Volume 14, Issue 3 (2019)

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Expert Opinion on Drug Discovery, Volume 14, Issue 3 (2019)

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Editorial

Editorial
Could advances in representation learning in Artificial Intelligence provide the new paradigm for data integration in drug discovery?
Vinaya Vijayan, Andrew D. Rouillard, Deepak K. Rajpal & Pankaj Agarwal
Pages: 191-194
Published online: 30 Jan 2019
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Editorial
The impact of perampanel and targeting AMPA transmission on anti-seizure drug discovery
Simona Lattanzi & Pasquale Striano
Pages: 195-197
Published online: 11 Jan 2019
First Page PreviewforThe impact of perampanel and targeting AMPA transmission on anti-seizure drug discovery | Full Text | References | PDF (418.4 KB) | EPUB
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Perspective

Article
Successes, failures, and future prospects of prodrugs and their clinical impact
Anas Najjar & Rafik Karaman
Pages: 199-220
Published online: 04 Feb 2019
AbstractforSuccesses, failures, and future prospects of prodrugs and their clinical impact | Full Text | References | PDF (2.8 MB) | EPUB
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Review

Review
Strategies to optimize drug half-life in lead candidate identification
Fabio Broccatelli, Cornelis E.C.A Hop & Matthew Wright
Pages: 221-230
Published online: 24 Jan 2019
AbstractforStrategies to optimize drug half-life in lead candidate identification | Full Text | References | PDF (1.4 MB) | EPUB
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Review
Novel approaches for designing drugs that interfere with pH regulation
Emanuela Berrino & Claudiu T. Supuran
Pages: 231-248
Published online: 25 Jan 2019
AbstractforNovel approaches for designing drugs that interfere with pH regulation | Full Text | References | PDF (2 MB) | EPUB
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Review
Recent developments in biological aspects of chalcones: the odyssey continues
Anu Rani, Amit Anand, Kewal Kumar & Vipan Kumar
Pages: 249-288
Published online: 18 Feb 2019
AbstractforRecent developments in biological aspects of chalcones: the odyssey continues | Full Text | References | PDF (7 MB) | EPUB
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Review
Anticancer drug discovery using multicellular tumor spheroid models
Michele Zanoni, Sara Pignatta, Chiara Arienti, Massimiliano Bonafè & Anna Tesei
Pages: 289-301
Published online: 28 Jan 2019
AbstractforAnticancer drug discovery using multicellular tumor spheroid models | Full Text | References | PDF (1.3 MB) | EPUB
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Review
An assessment of the translational relevance of Drosophila in drug discovery
Katerina Papanikolopoulou, Amrit Mudher & Efthimios Skoulakis
Pages: 303-313
Published online: 21 Jan 2019
AbstractforAn assessment of the translational relevance of Drosophila in drug discovery | Full Text | References | PDF (1 MB) | EPUB
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Review
Animal models of ischemic stroke and their impact on drug discovery
Dirk M. Hermann, Aurel Popa-Wagner, Christoph Kleinschnitz & Thorsten R. Doeppner
Pages: 315-326
Published online: 04 Feb 2019
AbstractforAnimal models of ischemic stroke and their impact on drug discovery | Full Text | References | PDF (1 MB) | EPUB
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