Expert Opinion on Drug Discovery, Volume 16, Issue 10 (2021)

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Expert Opinion on Drug Discovery, Volume 16, Issue 10 (2021)

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Editorial

Editorial
How can we accelerate COVID-19 vaccine discovery?
Giulia Russo, Valentina Di Salvatore, Filippo Caraci, Cristina Curreli, Marco Viceconti & Francesco Pappalardo
Pages: 1081-1084
Published online: 08 Jun 2021
First Page PreviewforHow can we accelerate COVID-19 vaccine discovery? | Full Text | References | PDF (1.1 MB) | EPUB
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Editorial
Advantages and disadvantages of mouse models of chronic lymphocytic leukemia in drug discovery
Heribert Playa-Albinyana, Fabian Arenas & Dolors Colomer
Pages: 1085-1090
Published online: 11 Jun 2021
First Page PreviewforAdvantages and disadvantages of mouse models of chronic lymphocytic leukemia in drug discovery | Full Text | References | PDF (4.8 MB) | EPUB
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Drug Discovery Case History

Article
The pre-clinical discovery and development of osimertinib used to treat non-small cell lung cancer
Florian Wittlinger & Stefan A. Laufer
Pages: 1091-1103
Published online: 20 Jun 2021
AbstractforThe pre-clinical discovery and development of osimertinib used to treat non-small cell lung cancer | Full Text | References | PDF (646.2 KB) | EPUB
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Review

Approaches for refining and furthering the development of CAR-based T cell therapies for solid malignancies
Caroline M Hull & John Maher
Pages: 1105-1117
Published online: 26 May 2021
AbstractforApproaches for refining and furthering the development of CAR-based T cell therapies for solid malignancies | Full Text | References | PDF (822.9 KB) | EPUB
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1,2,3,4-Tetrahydroisoquinoline (THIQ) as privileged scaffold for anticancer de novo drug design
Faheem, Banoth Karan Kumar, Kondapalli Venkata Gowri Chandra Sekhar, Subhash Chander, Selvaraj Kunjiappan & Sankaranarayanan Murugesan
Pages: 1119-1147
Published online: 28 Apr 2021
Abstractfor1,2,3,4-Tetrahydroisoquinoline (THIQ) as privileged scaffold for anticancer de novo drug design | Full Text | References | PDF (6.8 MB) | EPUB
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An overview of ProTide technology and its implications to drug discovery
Michaela Serpi & Fabrizio Pertusati
Pages: 1149-1161
Published online: 24 May 2021
AbstractforAn overview of ProTide technology and its implications to drug discovery | Full Text | References | PDF (982.1 KB) | EPUB
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Advances in venom peptide drug discovery: where are we at and where are we heading?
Taylor B. Smallwood & Richard J. Clark
Pages: 1163-1173
Published online: 24 May 2021
AbstractforAdvances in venom peptide drug discovery: where are we at and where are we heading? | Full Text | References | PDF (1.8 MB) | EPUB
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Computational representations of protein–ligand interfaces for structure-based virtual screening
Tong Qin, Zihao Zhu, Xiang Simon Wang, Jie Xia & Song Wu
Pages: 1175-1192
Published online: 03 Jun 2021
AbstractforComputational representations of protein–ligand interfaces for structure-based virtual screening | Full Text | References | PDF (1.9 MB) | EPUB
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The identification of farnesoid X receptor modulators as treatment options for nonalcoholic fatty liver disease
Stefano Fiorucci, Michele Biagioli, Monia Baldoni, Patrizia Ricci, Valentina Sepe, Angela Zampella & Eleonora Distrutti
Pages: 1193-1208
Published online: 05 May 2021
AbstractforThe identification of farnesoid X receptor modulators as treatment options for nonalcoholic fatty liver disease | Full Text | References | PDF (521.2 KB) | EPUB
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Advances in the discovery of novel agents for the treatment of glaucoma
Francesco Mincione, Alessio Nocentini & Claudiu T. Supuran
Pages: 1209-1225
Published online: 18 May 2021
AbstractforAdvances in the discovery of novel agents for the treatment of glaucoma | Full Text | References | PDF (1.9 MB) | EPUB
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