Expert Opinion on Drug Discovery, Volume 16, Issue 11 (2021)

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Expert Opinion on Drug Discovery, Volume 16, Issue 11 (2021)

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Editorial

Editorial
How do we address neglected sulfur pharmacophores in drug discovery?
Michael J. Tilby & Michael C. Willis
Pages: 1227-1231
Published online: 02 Jul 2021
First Page PreviewforHow do we address neglected sulfur pharmacophores in drug discovery? | Full Text | References | PDF (318.2 KB) | EPUB
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Editorial
What is the current value of MM/PBSA and MM/GBSA methods in drug discovery?
Tiziano Tuccinardi
Pages: 1233-1237
Published online: 24 Jun 2021
First Page PreviewforWhat is the current value of MM/PBSA and MM/GBSA methods in drug discovery? | Full Text | References | PDF (312.2 KB) | EPUB
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Review

Review
Understanding collagen interactions and their targeted regulation by novel drugs
Marialucia Gallorini & Simone Carradori
Pages: 1239-1260
Published online: 01 Jun 2021
AbstractforUnderstanding collagen interactions and their targeted regulation by novel drugs | Full Text | References | PDF (2.6 MB) | EPUB
  • 301 Views
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Review
Applications of fluorine to the construction of bioisosteric elements for the purposes of novel drug discovery
Paul Richardson
Pages: 1261-1286
Published online: 10 Jun 2021
AbstractforApplications of fluorine to the construction of bioisosteric elements for the purposes of novel drug discovery | Full Text | References | PDF (2.7 MB) | EPUB
  • 857 Views
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Review
The design and discovery of phospholipase A2 inhibitors for the treatment of inflammatory diseases
Charikleia S. Batsika, Anna-Dimitra D. Gerogiannopoulou, Christiana Mantzourani, Sofia Vasilakaki & George Kokotos
Pages: 1287-1305
Published online: 15 Jul 2021
AbstractforThe design and discovery of phospholipase A2 inhibitors for the treatment of inflammatory diseases | Full Text | References | PDF (2.6 MB) | EPUB
  • 495 Views
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Review
An overview of rational design of mRNA-based therapeutics and vaccines
Kenneth K.W. To & William C.S. Cho
Pages: 1307-1317
Published online: 19 Jul 2021
AbstractforAn overview of rational design of mRNA-based therapeutics and vaccines | Full Text | References | PDF (742.2 KB) | EPUB
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Review
Advances in the discovery and development of melanoma drug therapies
Monica Chanda & Mark S. Cohen
Pages: 1319-1347
Published online: 19 Jul 2021
AbstractforAdvances in the discovery and development of melanoma drug therapies | Full Text | References | PDF (2.2 MB) | EPUB
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Review
An overview of the latest in state-of-the-art murine models for prostate cancer
Elisabete Nascimento-Gonçalves, Fernanda Seixas, Rita Ferreira, Bruno Colaço, Belmiro Parada & Paula A. Oliveira
Pages: 1349-1364
Published online: 05 Jul 2021
AbstractforAn overview of the latest in state-of-the-art murine models for prostate cancer | Full Text | References | PDF (4.1 MB) | EPUB
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Review
Modeling approaches for reducing safety-related attrition in drug discovery and development: a review on myelotoxicity, immunotoxicity, cardiovascular toxicity, and liver toxicity
Elena M. Tosca, Roberta Bartolucci, Paolo Magni & Italo Poggesi
Pages: 1365-1390
Published online: 28 Jun 2021
AbstractforModeling approaches for reducing safety-related attrition in drug discovery and development: a review on myelotoxicity, immunotoxicity, cardiovascular toxicity, and liver toxicity | Full Text | References | PDF (3.7 MB) | EPUB
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