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Volume 2, Issue 6

Expert Opinion on Drug Discovery

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Expert Opinion on Drug Discovery, Volume 2, Issue 6 (2007)

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Expert Opinion on Drug Discovery, Volume 2, Issue 6 (2007)

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Perspectives

Article

What to expect from rational drug design

Matthias Adam MA (London), Dr Phil. (Bielefeld)

Pages: 773-776

Published online: 26 Jul 2007

AbstractforWhat to expect from rational drug design | Full Text | References | PDF (97.3 KB)

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Reviews

Article

Modelling neurodegeneration in prion disease – applications for drug development

Kay M Uppington & David R Brown

Pages: 777-788

Published online: 26 Jul 2007

AbstractforModelling neurodegeneration in prion disease – applications for drug development | Full Text | References | PDF (233.6 KB)

34 Views
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Article

Novel assays and novel strains – promising routes to new antibiotics?

Stefano Donadio PhD, Letizia Brandi PhD, Paolo Monciardini PhD, Margherita Sosio PhD & Claudio O Gualerzi PhD

Pages: 789-798

Published online: 26 Jul 2007

AbstractforNovel assays and novel strains – promising routes to new antibiotics? | Full Text | References | PDF (187.2 KB)

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Article

How to design multi-target drugs

target search options in cellular networks

Tamás Korcsmáros, Máté S Szalay, Csaba Böde, István A Kovács & Péter Csermely PhD, DSc

Pages: 799-808

Published online: 26 Jul 2007

AbstractforHow to design multi-target drugs | Full Text | References | PDF (347.5 KB)

416 Views
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Article

Allylic structures in cancer drugs and body metabolites that control cell life and death

Norman S Radin PhD

Pages: 809-821

Published online: 26 Jul 2007

AbstractforAllylic structures in cancer drugs and body metabolites that control cell life and death | Full Text | References | PDF (195.4 KB)

74 Views
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Article

Spider peptide toxins as leads for drug development

Pierre Escoubas & Frank Bosmans

Pages: 823-835

Published online: 26 Jul 2007

AbstractforSpider peptide toxins as leads for drug development | Full Text | References | PDF (791.7 KB)

224 Views
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Article

In silico analysis of antifungal peptides

determining the lead template sequence of potent antifungal peptides

Saeed Soltani MSc, Keykhosrow Keymanesh MSc & Soroush Sardari PharmD, PhD

Pages: 837-847

Published online: 26 Jul 2007

AbstractforIn silico analysis of antifungal peptides | Full Text | References | PDF (251.1 KB)

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Article

Integration of pharmacokinetic/pharmacodynamic modeling and simulation in the development of new anti-infective agents – minimum inhibitory concentration versus time-kill curves

Stephan Schmidt BS, Edgar Schuck PhD, Vipul Kumar PhD, Olaf Burkhardt MD & Hartmut Derendorf PhD

Pages: 849-860

Published online: 26 Jul 2007

AbstractforIntegration of pharmacokinetic/pharmacodynamic modeling and simulation in the development of new anti-infective agents – minimum inhibitory concentration versus time-kill curves | Full Text | References | PDF (492.1 KB)

229 Views
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Article

New target agents in the treatment of colorectal cancer patients

the era after cetuximab and bevacizumab

Giuseppe Tonini MD PhD, Gaia Schiavon MD, Bruno Vincenzi MD & Daniele Santini MD PhD

Pages: 861-871

Published online: 26 Jul 2007

AbstractforNew target agents in the treatment of colorectal cancer patients | Full Text | References | PDF (143.2 KB)

35 Views
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Article

The discovery of vanadyl and zinc complexes for treating diabetes and metabolic syndromes

Hiromu Sakurai PhD

Pages: 873-887

Published online: 26 Jul 2007

AbstractforThe discovery of vanadyl and zinc complexes for treating diabetes and metabolic syndromes | Full Text | References | PDF (310 KB)

88 Views
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Article

Use of RNA in drug design

Irene M Lagoja PhD & Piet Herdewijn PhD

Pages: 889-903

Published online: 26 Jul 2007

AbstractforUse of RNA in drug design | Full Text | References | PDF (462.6 KB)

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