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Expert Opinion on Investigational Drugs
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Volume 14, Issue 7

Expert Opinion on Investigational Drugs

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Expert Opinion on Investigational Drugs, Volume 14, Issue 7 (2005)

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Expert Opinion on Investigational Drugs, Volume 14, Issue 7 (2005)

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Editorial

Article

Small-molecule CRTH2 antagonists for the treatment of allergic inflammation: an overview

Tai Wei Ly & Kevin B Bacon

Pages: 769-773

Published online: 15 Jul 2005

AbstractforSmall-molecule CRTH2 antagonists for the treatment of allergic inflammation: an overview | References | PDF (71.9 KB)

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Review

Article

Ultra long-acting β₂-agonists in development for asthma and chronic obstructive pulmonary disease

Mario Cazzola, Maria Gabriella Matera & Jan Lötvall

Pages: 775-783

Published online: 15 Jul 2005

AbstractforUltra long-acting β₂-agonists in development for asthma and chronic obstructive pulmonary disease | References | PDF (117.1 KB)

421 Views
89 CrossRef citations
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Article

CCR1 antagonists in clinical development

James E Pease & Richard Horuk

Pages: 785-796

Published online: 15 Jul 2005

AbstractforCCR1 antagonists in clinical development | References | PDF (157.2 KB)

191 Views
30 CrossRef citations
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Article

Adenosine A_2A agonists in development for the treatment of inflammation

Courtney M Lappas, Gail W Sullivan & Joel Linden

Pages: 797-806

Published online: 15 Jul 2005

AbstractforAdenosine A_2A agonists in development for the treatment of inflammation | References | PDF (139.2 KB)

189 Views
101 CrossRef citations
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Article

Novel C5a regulators in inflammatory disease

Masashi Mizuno & Duncan S Cole

Pages: 807-821

Published online: 15 Jul 2005

AbstractforNovel C5a regulators in inflammatory disease | References | PDF (187.3 KB)

105 Views
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Article

The nitrosterols – a step forward from the steroid anti-inflammatory drugs?

Sheila A Doggrell

Pages: 823-828

Published online: 15 Jul 2005

AbstractforThe nitrosterols – a step forward from the steroid anti-inflammatory drugs? | References | PDF (81.9 KB)

31 Views
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Article

Novel treatments for food allergy

Laurent Pons & Wesley Burks

Pages: 829-834

Published online: 15 Jul 2005

AbstractforNovel treatments for food allergy | References | PDF (80.4 KB)

40 Views
6 CrossRef citations
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Article

Nitric oxide donor drugs: an update on pathophysiology and therapeutic potential

Roberto Scatena, Patrizia Bottoni, Giuseppe E Martorana & Bruno Giardina

Pages: 835-846

Published online: 15 Jul 2005

AbstractforNitric oxide donor drugs: an update on pathophysiology and therapeutic potential | References | PDF (139.9 KB)

330 Views
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Article

Short- and long-acting synthetic pentasaccharides as antithrombotic agents

Jeanine M Walenga, Walter P Jeske & Jawed Fareed

Pages: 847-858

Published online: 15 Jul 2005

AbstractforShort- and long-acting synthetic pentasaccharides as antithrombotic agents | References | PDF (135.3 KB)

59 Views
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Article

The use of cannabinoids in multiple sclerosis

Lara Teare & John Zajicek

Pages: 859-869

Published online: 15 Jul 2005

AbstractforThe use of cannabinoids in multiple sclerosis | References | PDF (135.2 KB)

89 Views
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Article

Antimalarial drugs: current status and new developments

Dharmendar Rathore, Thomas F McCutchan, Margery Sullivan & Sanjai Kumar

Pages: 871-883

Published online: 15 Jul 2005

AbstractforAntimalarial drugs: current status and new developments | References | PDF (183.2 KB)

238 Views
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Article

Novel agents in development for the treatment of melanoma

Ahmad A Tarhini & Sanjiv S Agarwala

Pages: 885-892

Published online: 15 Jul 2005

AbstractforNovel agents in development for the treatment of melanoma | References | PDF (98.2 KB)

49 Views
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Drug Evaluation

Article

Febuxostat: a non-purine, selective inhibitor of xanthine oxidase for the management of hyperuricaemia in patients with gout

H Ralph Schumacher Jr

Pages: 893-903

Published online: 15 Jul 2005

AbstractforFebuxostat: a non-purine, selective inhibitor of xanthine oxidase for the management of hyperuricaemia in patients with gout | References | PDF (207.7 KB)

264 Views
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Article

Stiripentol

Catherine Chiron

Pages: 905-911

Published online: 15 Jul 2005

AbstractforStiripentol | References | PDF (84.1 KB)

264 Views
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Key Paper Evaluation

Article

Safely slowing down the decline in Alzheimer’s disease: gene therapy shows potential

TUSZYNSKI MH, THAL L, PAY M et al.: A Phase I clinical trial of nerve growth factor gene therapy for Alzheimer’s disease. Nat. Med. (2005) 11(6):551-555.

Martin Braddock

Pages: 913-915

Published online: 15 Jul 2005

AbstractforSafely slowing down the decline in Alzheimer’s disease: gene therapy shows potential | References | PDF (48.6 KB)

50 Views
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Article

New drugs being developed for the treatment of tuberculosis

ANDRIES K, VERHASSELT P, GUILLEMOUNT J et al.: A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis. Science (2005) 307:223-227. JIA L, TOMASZEWSKI JE, HANRANHAN C et al.: Pharmacodynamics and pharmacokinetics of SQ-109, a new diamine-based antitubercular drug. Br. J. Pharmacol. (2005) 144:80-87.

Sheila A Doggrell

Pages: 917-920

Published online: 15 Jul 2005

AbstractforNew drugs being developed for the treatment of tuberculosis | References | PDF (53.1 KB)

69 Views
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