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Volume 20, Issue 8

Expert Opinion on Investigational Drugs

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Expert Opinion on Investigational Drugs, Volume 20, Issue 8 (2011)

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Expert Opinion on Investigational Drugs, Volume 20, Issue 8 (2011)

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Editorial

Article

Rational combinations of enzastaurin with novel targeted agents for patients with B-cell non-Hodgkin's lymphoma

Monica Civallero MS, Maria Cosenza MS, Alessia Bari MD & Stefano Sacchi MD

Pages: 1029-1031

Published online: 25 Jun 2011

First Page PreviewforRational combinations of enzastaurin with novel targeted agents for patients with B-cell non-Hodgkin's lymphoma | Full Text | References | PDF (542.6 KB)

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Article

Pitfalls of clinical trials on pharmacological treatment for obstructive sleep apnoea: future directions

Malcolm Kohler MD & John R Stradling

Pages: 1033-1037

Published online: 02 Jun 2011

AbstractforPitfalls of clinical trials on pharmacological treatment for obstructive sleep apnoea: future directions | Full Text | References | PDF (178.5 KB)

214 Views
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Original Research

Article

An investigation of the effect of sorafenib on tumour growth and recurrence after liver cancer resection in nude mice independent of phosphorylated extracellular signal-regulated kinase levels

Zheng Wang, Jie Hu, Shuang-Jian Qiu, Xiao-Wu Huang, Zhi Dai, Chang-Jun Tan, Jian Zhou & Jia Fan MD PHD

Pages: 1039-1045

Published online: 14 Jun 2011

AbstractforAn investigation of the effect of sorafenib on tumour growth and recurrence after liver cancer resection in nude mice independent of phosphorylated extracellular signal-regulated kinase levels | Full Text | References | PDF (365 KB)

279 Views
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Reviews

Article

Novel opioid antagonists for opioid-induced bowel dysfunction

Laura Diego, Rabia Atayee, Pieter Helmons, Grace Hsiao & Charles F von Gunten

Pages: 1047-1056

Published online: 12 Jun 2011

AbstractforNovel opioid antagonists for opioid-induced bowel dysfunction | Full Text | References | PDF (214.8 KB)

832 Views
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Article

New approaches to the treatment of nephropathy in diabetes

Merlin C Thomas MBChB PhD & Per-Henrik Groop MD DMSc

Pages: 1057-1071

Published online: 12 Jul 2011

AbstractforNew approaches to the treatment of nephropathy in diabetes | Full Text | References | PDF (436.4 KB)

791 Views
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Article

Opioid modulators for alcohol dependence

Thomas Hillemacher MD, Annemarie Heberlein MD, Marc AN Muschler MD, Stefan Bleich MD & Helge Frieling MD

Pages: 1073-1086

Published online: 09 Jun 2011

AbstractforOpioid modulators for alcohol dependence | Full Text | References | PDF (376.6 KB)

864 Views
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Article

Investigational drugs in thrombotic thrombocytopenic purpura

Patrizia Noris MD & Carlo L Balduini MD

Pages: 1087-1098

Published online: 10 Jun 2011

AbstractforInvestigational drugs in thrombotic thrombocytopenic purpura | Full Text | References | PDF (603.5 KB)

321 Views
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Article

Tumor treating fields: concept, evidence and future

Miklos Pless & Uri Weinberg

Pages: 1099-1106

Published online: 09 May 2011

AbstractforTumor treating fields: concept, evidence and future | Full Text | References | PDF (439.1 KB)

1435 Views
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Article

Triple reuptake inhibitors for treating subtypes of major depressive disorder: the monoamine hypothesis revisited

Jolanda Prins, Berend Olivier & S Mechiel Korte

Pages: 1107-1130

Published online: 20 Jun 2011

AbstractforTriple reuptake inhibitors for treating subtypes of major depressive disorder: the monoamine hypothesis revisited | Full Text | References | PDF (469.4 KB)

1593 Views
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Article

Investigational antibody drug conjugates for solid tumors

Puja Sapra, Andrea T Hooper, Christopher J O'Donnell & Hans-Peter Gerber

Pages: 1131-1149

Published online: 23 May 2011

AbstractforInvestigational antibody drug conjugates for solid tumors | Full Text | References | PDF (648.3 KB)

1687 Views
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Drug Evaluations

Article

Romidepsin: a novel histone deacetylase inhibitor for cancer

Erin M Bertino & Gregory A Otterson

Pages: 1151-1158

Published online: 24 Jun 2011

AbstractforRomidepsin: a novel histone deacetylase inhibitor for cancer | Full Text | References | PDF (194.8 KB)

1667 Views
122 CrossRef citations
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Article

A potential role of ruxolitinib in leukemia

Kiran Naqvi, Srdan Verstovsek, Hagop Kantarjian & Farhad Ravandi MD

Pages: 1159-1166

Published online: 03 Jun 2011

AbstractforA potential role of ruxolitinib in leukemia | Full Text | References | PDF (249.1 KB)

555 Views
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Article

Enzastaurin hydrochloride for lymphoma: reassessing the results of clinical trials in light of recent advances in the biology of B-cell malignancies

Loic Ysebaert & Franck Morschhauser

Pages: 1167-1174

Published online: 05 Jun 2011

AbstractforEnzastaurin hydrochloride for lymphoma: reassessing the results of clinical trials in light of recent advances in the biology of B-cell malignancies | Full Text | References | PDF (312.8 KB)

399 Views
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