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Volume 11, Issue 4

Expert Opinion on Drug Metabolism & Toxicology

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Expert Opinion on Drug Metabolism & Toxicology, Volume 11, Issue 4 (2015)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 11, Issue 4 (2015)

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Original Research

Article

Associated factors of drug–drug interactions of highly active antiretroviral therapy: report from a referral center

Maryam Farhoudi, Hossein Khalili (Professor of Clinical Pharmacy) , Iman Karimzadeh & Ladan Abbasian

Pages: 471-479

Published online: 05 Jan 2015

AbstractforAssociated factors of drug–drug interactions of highly active antiretroviral therapy: report from a referral center | Full Text | References | PDF (208 KB)

164 Views
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Article

Pharmacokinetic characteristics of fentanyl iontophoretic trandermal system over a range of applied current

J Brad Phipps PhD, Nitin Joshi PhD, Kelly A Regal PhD, Jinfang Li MS & Raymond S Sinatra MD

Pages: 481-489

Published online: 02 Mar 2015

AbstractforPharmacokinetic characteristics of fentanyl iontophoretic trandermal system over a range of applied current | Full Text | References | PDF (516.7 KB)

1484 Views
6 CrossRef citations
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Free Access

Review

Alterations in drug disposition in older adults

Emily Reeve (Postdoctoral Research Associate) BPharm (Hons) PhD, Michael D Wiese (Senior Lecturer in Pharmacotherapeutics) BPharm PhD & Arduino A Mangoni (Professor of Clinical Pharmacology) PhD FRCP FRACP

Pages: 491-508

Published online: 19 Jan 2015

AbstractforAlterations in drug disposition in older adults | Full Text | References | PDF (470.4 KB)

1996 Views
82 CrossRef citations
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Genotype-guided coumarin dosing: where are we now and where do we need to go next?

Ekaterina V Baranova MSc, Talitha I Verhoef MD PhD, Folkert W Asselbergs MD PhD, Anthonius de Boer MD PhD & Anke-Hilse Maitland-van der Zee PharmD PhD

Pages: 509-522

Published online: 16 Jan 2015

AbstractforGenotype-guided coumarin dosing: where are we now and where do we need to go next? | Full Text | References | PDF (366.9 KB)

308 Views
4 CrossRef citations
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Farnesoid x receptor in human metabolism and disease: the interplay between gene polymorphisms, clinical phenotypes and disease susceptibility

Ioannis Koutsounas, Stamatios Theocharis, Ioanna Delladetsima, Efstratios Patsouris & Constantinos Giaginis MSc PhD

Pages: 523-532

Published online: 02 Jan 2015

AbstractforFarnesoid x receptor in human metabolism and disease: the interplay between gene polymorphisms, clinical phenotypes and disease susceptibility | Full Text | References | PDF (402.1 KB)

483 Views
17 CrossRef citations
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Regulation of drug transporter expression and function in the placenta

Frantisek Staud (Professor) PhD & Martina Ceckova

Pages: 533-555

Published online: 20 Jan 2015

AbstractforRegulation of drug transporter expression and function in the placenta | Full Text | References | PDF (654.9 KB)

919 Views
38 CrossRef citations
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Cytochrome P450 time-dependent inhibition and induction: advances in assays, risk analysis and modelling

Robert J Riley (Vice President Drug Discovery) & Claire E Wilson (Group Leader DMPK)

Pages: 557-572

Published online: 08 Feb 2015

AbstractforCytochrome P450 time-dependent inhibition and induction: advances in assays, risk analysis and modelling | Full Text | References | PDF (932.4 KB)

1355 Views
18 CrossRef citations
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Prediction of drug clearance in children: a review of different methodologies

Iftekhar Mahmood PhD

Pages: 573-587

Published online: 04 Mar 2015

AbstractforPrediction of drug clearance in children: a review of different methodologies | Full Text | References | PDF (568.4 KB)

622 Views
16 CrossRef citations
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Recent advances in fluorination techniques and their anticipated impact on drug metabolism and toxicity

Cormac D Murphy (Senior Lecturer) PhD & Graham Sandford (Professor) PhD

Pages: 589-599

Published online: 02 Mar 2015

AbstractforRecent advances in fluorination techniques and their anticipated impact on drug metabolism and toxicity | Full Text | References | PDF (887 KB)

748 Views
61 CrossRef citations
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The role for microRNAs in drug toxicity and in safety assessment

April K Marrone, Frederick A Beland & Igor P Pogribny

Pages: 601-611

Published online: 05 Mar 2015

AbstractforThe role for microRNAs in drug toxicity and in safety assessment | Full Text | References | PDF (272.5 KB)

547 Views
31 CrossRef citations
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Drug Evaluation

Ipragliflozin, a sodium–glucose cotransporter 2 inhibitor, in the treatment of type 2 diabetes

Maka S Hedrington (Instructor in Medicine) MD MBA & Stephen N Davis (Theodore E. Woodward Professor of Medicine, Chairman, Physician-in-Chief) MBBS FRCP FACP

Pages: 613-623

Published online: 02 Feb 2015

AbstractforIpragliflozin, a sodium–glucose cotransporter 2 inhibitor, in the treatment of type 2 diabetes | Full Text | References | PDF (290.9 KB)

476 Views
10 CrossRef citations
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Cangrelor for the treatment of arterial thrombosis: pharmacokinetics/pharmacodynamics and clinical data

Eleonora Tamborini Permunian MD, Nicoletta Riva MD, Luigina Guasti MD & Alessandro Squizzato MD PhD

Pages: 625-637

Published online: 01 Mar 2015

AbstractforCangrelor for the treatment of arterial thrombosis: pharmacokinetics/pharmacodynamics and clinical data | Full Text | References | PDF (302.6 KB)

236 Views
6 CrossRef citations
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Pharmacokinetic/pharmacodynamic evaluation of eslicarbazepine for the treatment of epilepsy

Monika Banach, Kinga K Borowicz & Stanisław J Czuczwar

Pages: 639-648

Published online: 05 Mar 2015

AbstractforPharmacokinetic/pharmacodynamic evaluation of eslicarbazepine for the treatment of epilepsy | Full Text | References | PDF (301.8 KB)

366 Views
9 CrossRef citations
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Pharmacokinetic evaluation of fluvoxamine for the treatment of anxiety disorders

Alfredo Carlo Altamura MD, Alice Caldiroli MD & Massimiliano Buoli MD

Pages: 649-660

Published online: 01 Mar 2015

AbstractforPharmacokinetic evaluation of fluvoxamine for the treatment of anxiety disorders | Full Text | References | PDF (337.1 KB)

414 Views
14 CrossRef citations
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Expert Opinion on Drug Metabolism & Toxicology (Vol.11, Iss.4, 2015)

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