Expert Opinion on Drug Metabolism & Toxicology, Volume 12, Issue 3 (2016)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 12, Issue 3 (2016)

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Editorial

Editorial
Gene polymorphisms and therapy in rheumatoid arthritis
Santos Castañeda, Raquel López-Mejías & Miguel A. González-Gay
Pages: 225-229
Published online: 17 Feb 2016
First Page PreviewforGene polymorphisms and therapy in rheumatoid arthritis | Full Text | References | PDF (378.9 KB)
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Free Access

Reviews

Review
Pharmacokinetics of drugs in adult living donor liver transplant patients: regulatory factors and observations based on studies in animals and humans
Mi Li, Yang Zhao, Abhinav Humar, Amit D. Tevar, Christopher Hughes & Raman Venkataramanan
Pages: 231-243
Published online: 06 Feb 2016
AbstractforPharmacokinetics of drugs in adult living donor liver transplant patients: regulatory factors and observations based on studies in animals and humans | Full Text | References | PDF (988.6 KB) | Supplemental
  • 278 Views
  • 15 CrossRef citations
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Review
Regulation of drug-metabolizing enzymes by local and systemic liver injuries
Yan Guo, Bingfang Hu, Yang Xie, Timothy R. Billiar, Jason L. Sperry, Min Huang & Wen Xie
Pages: 245-251
Published online: 28 Jan 2016
AbstractforRegulation of drug-metabolizing enzymes by local and systemic liver injuries | Full Text | References | PDF (560.1 KB)
  • 265 Views
  • 14 CrossRef citations
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Review
Translational modeling and simulation approaches for molecularly targeted small molecule anticancer agents from bench to bedside
Shinji Yamazaki, Mary E. Spilker & Paolo Vicini
Pages: 253-265
Published online: 24 Feb 2016
AbstractforTranslational modeling and simulation approaches for molecularly targeted small molecule anticancer agents from bench to bedside | Full Text | References | PDF (1.6 MB)
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Review
Predicting and preventing antimicrobial resistance utilizing pharmacodynamics: Part I gram positive bacteria
Kristin E. Linder, David P. Nicolau & Michael D. Nailor
Pages: 267-280
Published online: 06 Feb 2016
AbstractforPredicting and preventing antimicrobial resistance utilizing pharmacodynamics: Part I gram positive bacteria | Full Text | References | PDF (1 MB)
  • 471 Views
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Review
Revisiting the role of nanoparticles as modulators of drug resistance and metabolism in cancer
Pranav Gupta, Khushboo A. Jani, Dong-Hua Yang, Mostafa Sadoqi, Emilio Squillante & Zhe-Sheng Chen
Pages: 281-289
Published online: 15 Feb 2016
AbstractforRevisiting the role of nanoparticles as modulators of drug resistance and metabolism in cancer | Full Text | References | PDF (870.8 KB)
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Review
Nuclear receptors and drug metabolism for the personalization of cancer therapy
Erika Cecchin, Elena De Mattia & Giuseppe Toffoli
Pages: 291-306
Published online: 01 Feb 2016
AbstractforNuclear receptors and drug metabolism for the personalization of cancer therapy | Full Text | References | PDF (1.2 MB)
  • 272 Views
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Review
On the pharmacogenetics of non-small cell lung cancer treatment
Mariacarmela Santarpia, Christian Rolfo, G. J. Peters, Leticia G. Leon & Elisa Giovannetti
Pages: 307-317
Published online: 17 Feb 2016
AbstractforOn the pharmacogenetics of non-small cell lung cancer treatment | Full Text | References | PDF (1.4 MB)
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Open Access

Drug Evaluations

Article
Evaluation of golimumab for the treatment of patients with active rheumatoid arthritis
Yoshiya Tanaka, Asako Senoo, Hideji Fujii & Daniel Baker
Pages: 319-326
Published online: 15 Feb 2016
AbstractforEvaluation of golimumab for the treatment of patients with active rheumatoid arthritis | Full Text | References | PDF (630.2 KB)
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Article
Pharmacokinetics and pharmacodynamics of MD1003 (high-dose biotin) in the treatment of progressive multiple sclerosis
Laure Peyro Saint Paul, Danièle Debruyne, Delphine Bernard, Donald M. Mock & Gilles L. Defer
Pages: 327-344
Published online: 17 Feb 2016
AbstractforPharmacokinetics and pharmacodynamics of MD1003 (high-dose biotin) in the treatment of progressive multiple sclerosis | Full Text | References | PDF (1.6 MB)
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Article
Pharmacological considerations in the use of stiripentol for the treatment of epilepsy
Alberto Verrotti, Giovanni Prezioso, Stefano Stagi, Maria Chiara Paolino & Pasquale Parisi
Pages: 345-352
Published online: 18 Feb 2016
AbstractforPharmacological considerations in the use of stiripentol for the treatment of epilepsy | Full Text | References | PDF (594.2 KB)
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Article
Pharmacodynamics and pharmacokinetics of elbasvir and grazoprevir in the treatment of hepatitis C
Nimisha Sulejmani, Syed-Mohammed Jafri & Stuart C. Gordon
Pages: 353-361
Published online: 24 Feb 2016
AbstractforPharmacodynamics and pharmacokinetics of elbasvir and grazoprevir in the treatment of hepatitis C | Full Text | References | PDF (746.3 KB)
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