Expert Opinion on Drug Metabolism & Toxicology, Volume 13, Issue 9 (2017)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 13, Issue 9 (2017)

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Editorial

Editorial
A decade of drug metabolite safety testing: industry and regulatory shared learning
Debra Luffer-Atlas & Aisar Atrakchi
Pages: 897-900
Published online: 11 Aug 2017
First Page PreviewforA decade of drug metabolite safety testing: industry and regulatory shared learning | Full Text | References | PDF (419.2 KB)
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Review

Review
Clarifying busulfan metabolism and drug interactions to support new therapeutic drug monitoring strategies: a comprehensive review
Alan L. Myers, Jitesh D. Kawedia, Richard E. Champlin, Mark A. Kramer, Yago Nieto, Romi Ghose & Borje S. Andersson
Pages: 901-923
Published online: 17 Aug 2017
AbstractforClarifying busulfan metabolism and drug interactions to support new therapeutic drug monitoring strategies: a comprehensive review | Full Text | References | PDF (1.6 MB)
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Review
Riding (High) into the danger zone: a review of potential differences in chemical exposures in fighter pilots resulting from high altitude and G-forces
Matthew W. Linakis, Kathleen M. Job, Xiaoxi Liu, Scott C. Collingwood, Heather A. Pangburn, Darrin K. Ott & Catherine M. T. Sherwin
Pages: 925-934
Published online: 20 Aug 2017
AbstractforRiding (High) into the danger zone: a review of potential differences in chemical exposures in fighter pilots resulting from high altitude and G-forces | Full Text | References | PDF (860.4 KB)
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Review
Highlights of drug - and herb- induced liver injury in the literature from 2016: how best to translate new information into clinical practice?
Omar Shahbaz, Sandeep Mahajan & James H. Lewis
Pages: 935-951
Published online: 28 Aug 2017
AbstractforHighlights of drug - and herb- induced liver injury in the literature from 2016: how best to translate new information into clinical practice? | Full Text | References | PDF (1.2 MB)
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Review
Curcumin as a clinically-promising anti-cancer agent: pharmacokinetics and drug interactions
Jeffry Adiwidjaja, Andrew J. McLachlan & Alan V. Boddy
Pages: 953-972
Published online: 10 Aug 2017
AbstractforCurcumin as a clinically-promising anti-cancer agent: pharmacokinetics and drug interactions | Full Text | References | PDF (1.9 MB)
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Review
Recent developments and future directions for the use of pharmacogenomics in cardiovascular disease treatments
Elliot Berinstein & Andrew Levy
Pages: 973-983
Published online: 20 Aug 2017
AbstractforRecent developments and future directions for the use of pharmacogenomics in cardiovascular disease treatments | Full Text | References | PDF (1,007.2 KB)
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Review
Biological anti-TNF drugs: immunogenicity underlying treatment failure and adverse events
Mônica Simon Prado, Klaus Bendtzen & Luis Eduardo Coelho Andrade
Pages: 985-995
Published online: 14 Aug 2017
AbstractforBiological anti-TNF drugs: immunogenicity underlying treatment failure and adverse events | Full Text | References | PDF (1,019 KB)
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Drug Evaluation

Article
Pharmacokinetic drug evaluation of lacosamide for the treatment of partial-onset seizures
Stefano de Biase, Mariarosaria Valente, Gian Luigi Gigli & Giovanni Merlino
Pages: 997-1005
Published online: 30 Jul 2017
AbstractforPharmacokinetic drug evaluation of lacosamide for the treatment of partial-onset seizures | Full Text | References | PDF (736.4 KB)
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Article
Pharmacokinetic/pharmacodynamic drug evaluation of benralizumab for the treatment of asthma
Maria Gabriella Matera, Luigino Calzetta, Barbara Rinaldi & Mario Cazzola
Pages: 1007-1013
Published online: 24 Jul 2017
AbstractforPharmacokinetic/pharmacodynamic drug evaluation of benralizumab for the treatment of asthma | Full Text | References | PDF (790.5 KB)
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Article
Evaluation of sofosbuvir, velpatasvir plus voxilaprevir as fixed-dose co-formulation for treating hepatitis C
Vicente Soriano, Laura Benítez-Gutiérrez, Ana Arias, Itziar Carrasco, Pablo Barreiro, Jose M. Peña & Carmen de Mendoza
Pages: 1015-1022
Published online: 28 Jul 2017
AbstractforEvaluation of sofosbuvir, velpatasvir plus voxilaprevir as fixed-dose co-formulation for treating hepatitis C | Full Text | References | PDF (911.1 KB)
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