Expert Opinion on Therapeutic Targets, Volume 23, Issue 3 (2019)

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Expert Opinion on Therapeutic Targets, Volume 23, Issue 3 (2019)

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Editorial

Editorial
E2F1 as a molecular drug target in ovarian cancer
Rossella Farra, Barbara Dapas, Mario Grassi, Fabio Benedetti & Gabriele Grassi
Pages: 161-164
Published online: 08 Feb 2019
First Page PreviewforE2F1 as a molecular drug target in ovarian cancer | Full Text | References | PDF (604.2 KB) | EPUB
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Review

Review
The P2X7 receptor: a new therapeutic target in Alzheimer’s disease
Peter Illes, Patrizia Rubini, Lumei Huang & Yong Tang
Pages: 165-176
Published online: 20 Feb 2019
AbstractforThe P2X7 receptor: a new therapeutic target in Alzheimer’s disease | Full Text | References | PDF (1.1 MB) | EPUB
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Article
Involvement of long non-coding RNA HULC (highly up-regulated in liver cancer) in pathogenesis and implications for therapeutic intervention
Christiane Klec, Tony Gutschner, Katrin Panzitt & Martin Pichler
Pages: 177-186
Published online: 24 Jan 2019
AbstractforInvolvement of long non-coding RNA HULC (highly up-regulated in liver cancer) in pathogenesis and implications for therapeutic intervention | Full Text | References | PDF (953.9 KB) | EPUB
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Article
The MAP kinase-interacting kinases (MNKs) as targets in oncology
Jianling Xie, James E. Merrett, Kirk B. Jensen & Christopher G. Proud
Pages: 187-199
Published online: 24 Jan 2019
AbstractforThe MAP kinase-interacting kinases (MNKs) as targets in oncology | Full Text | References | PDF (2 MB) | EPUB
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Article
GRK2 and GRK5 as therapeutic targets and their role in maladaptive and pathological cardiac hypertrophy
Melissa Lieu & Walter J. Koch
Pages: 201-214
Published online: 13 Feb 2019
AbstractforGRK2 and GRK5 as therapeutic targets and their role in maladaptive and pathological cardiac hypertrophy | Full Text | References | PDF (1.3 MB) | EPUB
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Article
The apelin/APJ system as a therapeutic target in metabolic diseases
Isabelle Castan-Laurell, Bernard Masri & Philippe Valet
Pages: 215-225
Published online: 10 Jan 2019
AbstractforThe apelin/APJ system as a therapeutic target in metabolic diseases | Full Text | References | PDF (1 MB) | EPUB
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Article
Neuronal and behavioral plasticity: the role of serotonin and BDNF systems tandem
Nina K. Popova & Vladimir S. Naumenko
Pages: 227-239
Published online: 12 Feb 2019
AbstractforNeuronal and behavioral plasticity: the role of serotonin and BDNF systems tandem | Full Text | References | PDF (1.1 MB) | EPUB
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Article
Targeting the cell signaling pathway Keap1-Nrf2 as a therapeutic strategy for adenocarcinomas of the lung
Bo Zhang, Zhiyuan Ma, Biqin Tan & Nengming Lin
Pages: 241-250
Published online: 27 Dec 2018
AbstractforTargeting the cell signaling pathway Keap1-Nrf2 as a therapeutic strategy for adenocarcinomas of the lung | Full Text | References | PDF (1,008.5 KB) | EPUB
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Original Research

Article
Functional genetic evaluation of DNA house-cleaning enzymes in the malaria parasite: dUTPase and Ap4AH are essential in Plasmodium berghei but ITPase and NDH are dispensable
Hirdesh Kumar, Jessica Kehrer, Mirko Singer, Miriam Reinig, Jorge M. Santos, Gunnar R. Mair & Friedrich Frischknecht
Pages: 251-261
Published online: 13 Feb 2019
AbstractforFunctional genetic evaluation of DNA house-cleaning enzymes in the malaria parasite: dUTPase and Ap4AH are essential in Plasmodium berghei but ITPase and NDH are dispensable | Full Text | References | PDF (1.6 MB) | EPUB | Supplemental
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