Future Medicinal Chemistry, Volume 11, Issue 17 (2019)

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Future Medicinal Chemistry, Volume 11, Issue 17 (2019)

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Editorial

Editorial
Discovery of a Macrocyclic γ-AApeptide Binding to lncRNA GAS5 and Its Therapeutic Implication in Type 2 Diabetes
Yan Shi, Niketa A Patel & Jianfeng Cai
Pages: 2233-2235
Published online: 04 Oct 2019
First Page PreviewforDiscovery of a Macrocyclic γ-AApeptide Binding to lncRNA GAS5 and Its Therapeutic Implication in Type 2 Diabetes | Full Text | References | PDF (169.4 KB) | EPUB
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Free Access
Editorial
Renal Targeting Delivery Systems
Zhi-xiang Yuan, Zhenghui Shang, Jian Gu & Lili He
Pages: 2237-2240
Published online: 04 Oct 2019
First Page PreviewforRenal Targeting Delivery Systems | Full Text | References | PDF (196.9 KB) | EPUB
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Commentary

Editorial
Management of Diabetic Nephropathy: The Role of Sirtuin-1
Wanning Wang, Weixia Sun, Yanli Cheng, Zhonggao Xu & Lu Cai
Pages: 2241-2245
Published online: 04 Oct 2019
First Page PreviewforManagement of Diabetic Nephropathy: The Role of Sirtuin-1 | Full Text | References | PDF (192.7 KB) | EPUB
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Short Communication

Brief Report
Benford's Law in Medicinal Chemistry: Implications for Drug Design
Alfonso T García-Sosa
Pages: 2247-2253
Published online: 04 Oct 2019
AbstractforBenford's Law in Medicinal Chemistry: Implications for Drug Design | Full Text | References | PDF (487.6 KB) | EPUB | Supplemental
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Research Article

Article
Topological Index Nclass as a Factor Determining the Antibacterial Activity of Quinolones against Escherichia Coli
Beatriz Suay-García, Pedro Alemán-López, José I Bueso-Bordils, Antonio Falcó, María T Pérez-Gracia & Gerardo M Antón-Fos
Pages: 2255-2262
Published online: 04 Oct 2019
AbstractforTopological Index Nclass as a Factor Determining the Antibacterial Activity of Quinolones against Escherichia Coli | Full Text | References | PDF (490.9 KB) | EPUB | Supplemental
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Article
Metformin Inhibits Angiogenesis of Endothelial Progenitor Cells via miR-221-mediated p27 Expression and Autophagy
Hai-Zhen Ni, Zhao Liu, Li-Li Sun, Min Zhou, Chen Liu, Wen-Dong Li & Xiao-Qiang Li
Pages: 2263-2272
Published online: 04 Oct 2019
AbstractforMetformin Inhibits Angiogenesis of Endothelial Progenitor Cells via miR-221-mediated p27 Expression and Autophagy | Full Text | References | PDF (1.4 MB) | EPUB
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Article
Carboranylanilinoquinazoline EGFR-Inhibitors: Toward ‘Lead-to-Candidate’ Stage in the Drug-Development Pipeline
Marcos Couto, Catalina Alamón, Carina Sánchez, Belén Dávila, Marcelo Fernández, Nicole Lecot, Pablo Cabral, Francesc Teixidor, Clara Viñas & Hugo Cerecetto
Pages: 2273-2285
Published online: 04 Oct 2019
AbstractforCarboranylanilinoquinazoline EGFR-Inhibitors: Toward ‘Lead-to-Candidate’ Stage in the Drug-Development Pipeline | Full Text | References | PDF (633.4 KB) | EPUB | Supplemental
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Review

Review Article
Targeting Cancer's Achilles’ Heel: Role of BCL-2 Inhibitors in Cellular Senescence and Apoptosis
Aarti Anantram & Mariam Degani
Pages: 2287-2312
Published online: 04 Oct 2019
AbstractforTargeting Cancer's Achilles’ Heel: Role of BCL-2 Inhibitors in Cellular Senescence and Apoptosis | Full Text | References | PDF (4.6 MB) | EPUB
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Review Article
From Biomedicinal to In Silico Models and Back to Therapeutics: A Review on the Advancement of Peptidic Modeling
Ana S Moura, Amit K Halder & M Natália DS Cordeiro
Pages: 2313-2331
Published online: 04 Oct 2019
AbstractforFrom Biomedicinal to In Silico Models and Back to Therapeutics: A Review on the Advancement of Peptidic Modeling | Full Text | References | PDF (544.1 KB) | EPUB
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Review Article
The Progress and Development of GLUT1 Inhibitors Targeting Cancer Energy Metabolism
Ying Meng, Xi Xu, Hongyu Luan, Lei Li, Wenhao Dai, Zhiyu Li & Jinlei Bian
Pages: 2333-2352
Published online: 04 Oct 2019
AbstractforThe Progress and Development of GLUT1 Inhibitors Targeting Cancer Energy Metabolism | Full Text | References | PDF (2.3 MB) | EPUB
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