Future Medicinal Chemistry, Volume 11, Issue 6 (2019)

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Future Medicinal Chemistry, Volume 11, Issue 6 (2019)

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Commentary

Editorial
Small Molecules As Central Nervous System Therapeutics: Old challenges, New directions, and a Philosophic Divide
William A Banks & Nigel H Greig
Pages: 489-493
Published online: 26 Mar 2019
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Free Access
Editorial
The Growing Landscape of Metabolomics and Lipidomics: Applications to Medicinal Chemistry and Drug Discovery
Gustavo Palacios, John J Bowling & Alireza Abdolvahabi
Pages: 495-498
Published online: 19 Mar 2019
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Short Communication

Brief Report
Novel 1,3,4-oxadiazoles As Antitubercular Agents With Limited Activity Against drug-resistant Tuberculosis
Vitthal B Makane, Vagolu Siva Krishna, Eruva Vamshi Krishna, Manjulika Shukla, Balakrishnan Mahizhaveni, Sunil Misra, Sidharth Chopra, Dharmarajan Sriram, Vijayan N Azger Dusthackeer & Haridas B Rode
Pages: 499-510
Published online: 20 Mar 2019
AbstractforNovel 1,3,4-oxadiazoles As Antitubercular Agents With Limited Activity Against drug-resistant Tuberculosis | Full Text | References | PDF (910.1 KB) | EPUB | Supplemental
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Research Article

Article
High-throughput Hydrogen Bond Strength Calculation and Its Applications in Optimizing Drug ADME Properties
Jie Shen, Ying Yang, Howard Broughton, Ian A Watson & Prashant V Desai
Pages: 511-524
Published online: 20 Mar 2019
AbstractforHigh-throughput Hydrogen Bond Strength Calculation and Its Applications in Optimizing Drug ADME Properties | Full Text | References | PDF (3.6 MB) | EPUB | Supplemental
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Article
Indole-3-glyoxyl Tyrosine: Synthesis and Antimalarial Activity Against Plasmodium Falciparum
Stanley NS Vasconcelos, Kamila A Meissner, Witor R Ferraz, Gustavo HG Trossini, Carsten Wrenger & Hélio A Stefani
Pages: 525-538
Published online: 27 Mar 2019
AbstractforIndole-3-glyoxyl Tyrosine: Synthesis and Antimalarial Activity Against Plasmodium Falciparum | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
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Article
Synthesis and In Vitro Evaluation of New Translocator Protein Ligands Designed for Positron Emission Tomography
Thomas Kalina, Neydher Berroterán-Infante, Stefan Schmitl, Chrysoula Vraka, Marcus Hacker, Markus Mitterhauser, Katharina Pallitsch & Wolfgang Wadsak
Pages: 539-550
Published online: 19 Mar 2019
AbstractforSynthesis and In Vitro Evaluation of New Translocator Protein Ligands Designed for Positron Emission Tomography | Full Text | References | PDF (516.6 KB) | EPUB | Supplemental
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Review

Review Article
Developing RNA Aptamers for Potential Treatment of Neurological Diseases
Zhen Huang & Li Niu
Pages: 551-565
Published online: 26 Mar 2019
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Review Article
Deep Learning for Molecular Generation
Youjun Xu, Kangjie Lin, Shiwei Wang, Lei Wang, Chenjing Cai, Chen Song, Luhua Lai & Jianfeng Pei
Pages: 567-597
Published online: 30 Jan 2019
AbstractforDeep Learning for Molecular Generation | Full Text | References | PDF (3.5 MB) | EPUB
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Review Article
Peeking at G-protein-coupled Receptors Through the Molecular Dynamics Keyhole
Giuseppe Deganutti, Stefano Moro & Christopher A Reynolds
Pages: 599-615
Published online: 19 Mar 2019
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Open Access
Review Article
State of the Art of Smo Antagonists for Cancer Therapy: Advances in the Target Receptor and New Ligand Structures
Christian Espinosa-Bustos, Jaime Mella, Jorge Soto-Delgado & Cristian O Salas
Pages: 617-638
Published online: 26 Mar 2019
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