Leukemia & Lymphoma, Volume 53, Issue 7 (2012)

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Leukemia & Lymphoma, Volume 53, Issue 7 (2012)

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Commentary on selected articles in this issue

Article Commentary
Improving quality of life in chronic lymphocytic leukemia
Clive S. Zent
Pages: 1247-1248
Published online: 13 Feb 2012
CitationforImproving quality of life in chronic lymphocytic leukemia | Full Text | References | PDF (128.1 KB) | Supplemental
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Commentary

Article Commentary
Bendamustine: more ammunition in the battle against mantle cell lymphoma
Julie E. Chang & Brad S. Kahl
Pages: 1249-1250
Published online: 31 Jan 2012
CitationforBendamustine: more ammunition in the battle against mantle cell lymphoma | Full Text | References | PDF (133.7 KB) | Supplemental
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Article Commentary
Sudden blast crisis in chronic myeloid leukemia treated with tyrosine kinase inhibitors
Devendra K. Hiwase & Timothy P. Hughes
Pages: 1251-1252
Published online: 23 Apr 2012
CitationforSudden blast crisis in chronic myeloid leukemia treated with tyrosine kinase inhibitors | Full Text | References | PDF (130.1 KB) | Supplemental
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Article Commentary
Multiple myeloma and immunomodulation: regulating the regulatory cells
Chitta S. Kasyapa, Taimur Sher & Asher A. Chanan-Khan
Pages: 1253-1254
Published online: 03 Apr 2012
CitationforMultiple myeloma and immunomodulation: regulating the regulatory cells | Full Text | References | PDF (184.8 KB) | Supplemental
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Article Commentary
A new purpose for an old drug: inhibiting autophagy with clarithromycin
Jessica K. Altman & Leonidas C. Platanias
Pages: 1255-1256
Published online: 13 Mar 2012
CitationforA new purpose for an old drug: inhibiting autophagy with clarithromycin | Full Text | References | PDF (130.5 KB) | Supplemental
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Review

Review Article
Adolescents with Hodgkin lymphoma: old children or young adults?
Dennis A. Eichenauer, Peter Borchmann & Andreas Engert
Pages: 1257-1262
Published online: 31 Jan 2012
AbstractforAdolescents with Hodgkin lymphoma: old children or young adults? | Full Text | References | PDF (288.1 KB) | Supplemental
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Review Article

Review Article
Targeted therapy for patients with chronic myeloid leukemia: clinical trial experience and challenges in inter-trial comparisons
Ramon Tiu & Matt Kalaycio
Pages: 1263-1272
Published online: 31 Jan 2012
AbstractforTargeted therapy for patients with chronic myeloid leukemia: clinical trial experience and challenges in inter-trial comparisons | Full Text | References | PDF (284.6 KB) | Supplemental
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Review Article
Evolution of definitions of response, progression-free survival and event-free survival in front-line studies of chronic myeloid leukemia
George Ansstas & Ravi Vij
Pages: 1273-1281
Published online: 13 Feb 2012
AbstractforEvolution of definitions of response, progression-free survival and event-free survival in front-line studies of chronic myeloid leukemia | Full Text | References | PDF (213.7 KB) | Supplemental
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Original Articles Clinical

Article
p53 protein expression in chronic lymphocytic leukemia
Ludger Sellmann, Alexander Carpinteiro, Holger Nückel, René Scholtysik, Dörte Siemer, Ludger Klein-Hipass, Dieter Kube, Jan Dürig, Ulrich Dührsen, Jens Stanelle & Ralf Küppers
Pages: 1282-1288
Published online: 13 Feb 2012
Abstractforp53 protein expression in chronic lymphocytic leukemia | Full Text | References | PDF (300.2 KB) | Supplemental
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Research Article

Article
Quality of life in chronic lymphocytic leukemia: 5-year results from the multicenter randomized LRF CLL4 trial
Monica Else, Kim Cocks, Shirley Crofts, Rachel Wade, Sue M. Richards, Daniel Catovsky, Alastair G. Smith & For The UK National Cancer Research Institute (NCRI) Chronic Lymphocytic Leukaemia Trials Group
Pages: 1289-1298
Published online: 01 Mar 2012
AbstractforQuality of life in chronic lymphocytic leukemia: 5-year results from the multicenter randomized LRF CLL4 trial | Full Text | References | PDF (429 KB) | Supplemental
  • 674 Views
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Article
A retrospective study evaluating the efficacy and safety of bendamustine in the treatment of mantle cell lymphoma
Sean Warsch, Peter J. Hosein, Lauren S. Maeda, Ash A. Alizadeh & Izidore S. Lossos
Pages: 1299-1305
Published online: 31 Jan 2012
AbstractforA retrospective study evaluating the efficacy and safety of bendamustine in the treatment of mantle cell lymphoma | Full Text | References | PDF (246 KB) | Supplemental
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Article
High baseline serum thymidine kinase 1 level predicts unfavorable outcome in patients with follicular lymphoma
Vít Procházka, Edgar Faber, Luděk Raida, Kateřina Langová, Karel Indrák & Tomáš Papajík
Pages: 1306-1310
Published online: 21 Feb 2012
AbstractforHigh baseline serum thymidine kinase 1 level predicts unfavorable outcome in patients with follicular lymphoma | Full Text | References | PDF (205 KB) | Supplemental
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Article
Non-Hodgkin lymphoma in Chile: a review of 207 consecutive adult cases by a panel of five expert hematopathologists
Maria Elena Cabrera, Virginia Martinez, Bharat N. Nathwani, H. Konrad Muller-Hermelink, Jacques Diebold, Kenneth A. MacLennan, James Armitage & Dennis D. Weisenburger
Pages: 1311-1317
Published online: 13 Mar 2012
AbstractforNon-Hodgkin lymphoma in Chile: a review of 207 consecutive adult cases by a panel of five expert hematopathologists | Full Text | References | PDF (209.5 KB) | Supplemental
  • 298 Views
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Article
Efficacy of lenalidomide plus dexamethasone in patients older than 75 years with relapsed multiple myeloma
Cyrille Touzeau, Nicolas Blin, Aline Clavert, Virginie Roland, Marion Loirat, Benoit Tessoulin, Steven Le Gouill, Lucie Planche, Martine Pennetier, Beatrice Mahe, Mohamad Mohty, Florent Malard, Pierre Peterlin, Viviane Dubruille & Philippe Moreau
Pages: 1318-1320
Published online: 31 Jan 2012
AbstractforEfficacy of lenalidomide plus dexamethasone in patients older than 75 years with relapsed multiple myeloma | Full Text | References | PDF (174.1 KB) | Supplemental
  • 630 Views
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Article
Long-term follow-up of patients with chronic myeloid leukemia in chronic phase developing sudden blast phase on imatinib therapy
Adisak Tantiworawit, Maryse M. Power, Michael J. Barnett, Donna E. Hogge, Stephen H. Nantel, Thomas J. Nevill, John D. Shepherd, Kevin W. Song, Heather J. Sutherland, Cynthia L. Toze, Yasser R. Abou-Mourad, Sujaatha Narayanan, Raewyn C. Broady & Donna L. Forrest
Pages: 1321-1326
Published online: 05 Mar 2012
AbstractforLong-term follow-up of patients with chronic myeloid leukemia in chronic phase developing sudden blast phase on imatinib therapy | Full Text | References | PDF (204.7 KB) | Supplemental
  • 367 Views
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Article
Association between methylenetetrahydrofolate reductase polymorphism C677T and risk of chronic myeloid leukemia in Serbian population
Ksenija Jakovljevic, Emina Malisic, Milena Cavic, Sinisa Radulovic & Radmila Jankovic
Pages: 1327-1330
Published online: 03 Jan 2012
AbstractforAssociation between methylenetetrahydrofolate reductase polymorphism C677T and risk of chronic myeloid leukemia in Serbian population | Full Text | References | PDF (160.9 KB) | Supplemental
  • 90 Views
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Article
A phase I dose-escalation study of clofarabine in combination with fractionated gemtuzumab ozogamicin in patients with refractory or relapsed acute myeloid leukemia
Matthew C. Foster, Chirag Amin, Peter M. Voorhees, Hendrik W. van Deventer, Kristy L. Richards, Anastasia Ivanova, Jennifer Whitman, Wingkeung Michael Chiu, Nathan D. Barr & Thomas Shea
Pages: 1331-1337
Published online: 31 Jan 2012
AbstractforA phase I dose-escalation study of clofarabine in combination with fractionated gemtuzumab ozogamicin in patients with refractory or relapsed acute myeloid leukemia | Full Text | References | PDF (205.5 KB) | Supplemental
  • 414 Views
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Article
Systemic mastocytosis is uncommon in KIT D816V mutation positive core-binding factor acute myeloid leukemia
Thomas Kristensen, Birgitte Preiss, Sigurd Broesby-Olsen, Hanne Vestergaard, Lone Friis & Michael Boe Møller
Pages: 1338-1344
Published online: 31 Jan 2012
AbstractforSystemic mastocytosis is uncommon in KIT D816V mutation positive core-binding factor acute myeloid leukemia | Full Text | References | PDF (346.5 KB) | Supplemental
  • 301 Views
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Article
Thymidylate synthase polymorphisms and hematological cancer risk: a meta-analysis
Yu Weng, Jun Zhang, Xue Tang, Xinyou Xie & Guangdi Chen
Pages: 1345-1351
Published online: 31 Jan 2012
AbstractforThymidylate synthase polymorphisms and hematological cancer risk: a meta-analysis | Full Text | References | PDF (187.2 KB) | Supplemental
  • 176 Views
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Article
Intensive care unit management of patients with newly diagnosed acute myeloid leukemia with no organ failure
Etienne Lengliné, Emmanuel Raffoux, Virginie Lemiale, Michael Darmon, Emmanuel Canet, Nicolas Boissel, Benoît Schlemmer, Hervé Dombret & Elie Azoulay
Pages: 1352-1359
Published online: 13 Feb 2012
AbstractforIntensive care unit management of patients with newly diagnosed acute myeloid leukemia with no organ failure | Full Text | References | PDF (263.5 KB) | Supplemental
  • 686 Views
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Article
Functional polymorphisms in FAS, FASL and CASP8 genes and risk of childhood acute lymphoblastic leukemia: a case–control study
Na Tong, Limei Zhang, Xiaojing Sheng, Meilin Wang, Zhizhong Zhang, Yongjun Fang, Yao Xue, Jie Li & Zhengdong Zhang
Pages: 1360-1366
Published online: 31 Jan 2012
AbstractforFunctional polymorphisms in FAS, FASL and CASP8 genes and risk of childhood acute lymphoblastic leukemia: a case–control study | Full Text | References | PDF (192.4 KB) | Supplemental
  • 159 Views
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Original Articles Research

Article
The Hsp90 inhibitor SNX-7081 synergizes with and restores sensitivity to fludarabine in chronic lymphocytic leukemia cells with lesions in the TP53 pathway: a potential treatment strategy for fludarabine refractory disease
O. Giles Best, Yiping Che, Nisha Singh, Cecily Forsyth, Richard I. Christopherson & Stephen P. Mulligan
Pages: 1367-1375
Published online: 31 Jan 2012
AbstractforThe Hsp90 inhibitor SNX-7081 synergizes with and restores sensitivity to fludarabine in chronic lymphocytic leukemia cells with lesions in the TP53 pathway: a potential treatment strategy for fludarabine refractory disease | Full Text | References | PDF (428 KB) | Supplemental
  • 276 Views
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Research Article

Article
Curcumin potentiates antitumor activity of l-asparaginase via inhibition of the AKT signaling pathway in acute lymphoblastic leukemia
Hua Wang, Qi-Rong Geng, Liang Wang & Yue Lu
Pages: 1376-1382
Published online: 25 Jan 2012
AbstractforCurcumin potentiates antitumor activity of l-asparaginase via inhibition of the AKT signaling pathway in acute lymphoblastic leukemia | Full Text | References | PDF (482.3 KB) | Supplemental
  • 333 Views
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Article
Effect of phosphatase and tensin homology deleted on chromosome 10 (PTEN) gene transfection on reversal of multidrug resistance in K562/ADM cells
Zhiyong Cheng, Ning Yang, Wentong Liang, Xiaoyan Yan, Lin Li & Ling Pan
Pages: 1383-1389
Published online: 31 Jan 2012
AbstractforEffect of phosphatase and tensin homology deleted on chromosome 10 (PTEN) gene transfection on reversal of multidrug resistance in K562/ADM cells | Full Text | References | PDF (310.8 KB) | Supplemental
  • 278 Views
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Article
CD40 ligand is necessary and sufficient to support primary diffuse large B-cell lymphoma cells in culture: a tool for in vitro preclinical studies with primary B-cell malignancies
Daisuke Ito, Aric M. Frantz, Christina Williams, Rachael Thomas, Robert C. Burnett, Anne C. Avery, Matthew Breen, Nicola J. Mason, Timothy D. O’Brien & Jaime F. Modiano
Pages: 1390-1398
Published online: 03 Feb 2012
AbstractforCD40 ligand is necessary and sufficient to support primary diffuse large B-cell lymphoma cells in culture: a tool for in vitro preclinical studies with primary B-cell malignancies | Full Text | References | PDF (486.3 KB) | Supplemental
  • 594 Views
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Article
Importance of inducible multidrug resistance 1 expression in HL-60 cells resistant to gemtuzumab ozogamicin
Taichi Matsumoto, Shiro Jimi, Shuuji Hara, Yasushi Takamatsu, Junji Suzumiya & Kazuo Tamura
Pages: 1399-1405
Published online: 13 Feb 2012
AbstractforImportance of inducible multidrug resistance 1 expression in HL-60 cells resistant to gemtuzumab ozogamicin | Full Text | References | PDF (346.8 KB) | Supplemental
  • 276 Views
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Letters to the Editor

Letter
Induction by lenalidomide and dexamethasone combination increases regulatory cells of patients with previously untreated multiple myeloma
Karthick Raja Muthu Raja, Lucie Kovarova & Roman Hajek
Pages: 1406-1408
Published online: 31 Jan 2012
First Page PreviewforInduction by lenalidomide and dexamethasone combination increases regulatory cells of patients with previously untreated multiple myeloma | Full Text | References | PDF (145.7 KB) | Supplemental
  • 382 Views
  • 27 CrossRef citations
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Letter

Letter
Clarithromycin potentiates tyrosine kinase inhibitor treatment in patients with resistant chronic myeloid leukemia
Angelo Michele Carella, Germana Beltrami, Gianmatteo Pica, Andrea Carella & Gioacchino Catania
Pages: 1409-1411
Published online: 13 Feb 2012
First Page PreviewforClarithromycin potentiates tyrosine kinase inhibitor treatment in patients with resistant chronic myeloid leukemia | Full Text | References | PDF (141.3 KB) | Supplemental
  • 346 Views
  • 17 CrossRef citations
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Letter
Sustained complete molecular response of chronic myeloid leukemia after discontinuation of second-generation tyrosine kinase inhibitors
Jun Aoki, Kazuteru Ohashi, Takeshi Kobayashi, Kazuhiko Kakihana, Yuka Hirashima & Hisashi Sakamaki
Pages: 1412-1414
Published online: 31 Jan 2012
First Page PreviewforSustained complete molecular response of chronic myeloid leukemia after discontinuation of second-generation tyrosine kinase inhibitors | Full Text | References | PDF (218.4 KB) | Supplemental
  • 254 Views
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Letter
Impact of palifermin on mucosal toxicity in autologous stem cell transplants using busulfan–melphalan conditioning chemotherapy for Hodgkin and non-Hodgkin lymphoma
Philip Campbell, Adam Friebe, Paul Foulstone, Andrew Grigg, Jennifer Hempton & Ashish Bajel
Pages: 1415-1416
Published online: 31 Jan 2012
CitationforImpact of palifermin on mucosal toxicity in autologous stem cell transplants using busulfan–melphalan conditioning chemotherapy for Hodgkin and non-Hodgkin lymphoma | Full Text | References | PDF (139.2 KB) | Supplemental
  • 248 Views
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Letter
First-line treatment with imatinib mesylate in patients with chronic phase chronic myeloid leukemia: experience of a public hospital in a developing country of South America
Carlos Alberto Pinto da Silveira & Iris Ferrari
Pages: 1417-1419
Published online: 31 Jan 2012
First Page PreviewforFirst-line treatment with imatinib mesylate in patients with chronic phase chronic myeloid leukemia: experience of a public hospital in a developing country of South America | Full Text | References | PDF (165.3 KB) | Supplemental
  • 84 Views
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Letter
No evidence for DNA methylation of the ATM promoter CpG island in chronic lymphocytic leukemia
Thomas Mikeska, Dennis A. Carney, John F. Seymour & Alexander Dobrovic
Pages: 1420-1422
Published online: 31 Jan 2012
First Page PreviewforNo evidence for DNA methylation of the ATM promoter CpG island in chronic lymphocytic leukemia | Full Text | References | PDF (184.7 KB) | Supplemental
  • 186 Views
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Letter
Helicobacter pylori-induced thrombocytosis clinically indistinguishable from essential thrombocythemia
Toyotaka Kawamata & Arinobu Tojo
Pages: 1423-1424
Published online: 31 Jan 2012
CitationforHelicobacter pylori-induced thrombocytosis clinically indistinguishable from essential thrombocythemia | Full Text | References | PDF (155.1 KB) | Supplemental
  • 127 Views
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Letter
Immunoglobulin/T-cell receptor gene rearrangements in the diagnostic paradigm of pediatric patients with T-cell acute lymphoblastic leukemia
Monika D. Kraszewska, Małgorzata Dawidowska, Maria Kosmalska, Łukasz Sędek, Władysław Grzeszczak, Tomasz Szczepański, Michał Witt & The Polish Pediatric Leukemia Lymphoma Study Group(PPLLSG)
Pages: 1425-1428
Published online: 16 Mar 2012
First Page PreviewforImmunoglobulin/T-cell receptor gene rearrangements in the diagnostic paradigm of pediatric patients with T-cell acute lymphoblastic leukemia | Full Text | References | PDF (154.3 KB) | Supplemental
  • 219 Views
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Letter
Paroxysmal nocturnal hemoglobinuria-myelodysplastic syndrome associated with marked thrombocytosis and acquired clonal cytogenetic abnormality of t(3;12)(q28;q15)
Eun-Jeong Won, Hye-Ran Kim, Seung-Yeob Lee, Hyun-Jung Choi, Stephanie Jane Won, Jong-Hee Shin, Soon-Pal Suh, Dong-Wook Ryang & Myung-Geun Shin
Pages: 1429-1432
Published online: 31 Jan 2012
First Page PreviewforParoxysmal nocturnal hemoglobinuria-myelodysplastic syndrome associated with marked thrombocytosis and acquired clonal cytogenetic abnormality of t(3;12)(q28;q15) | Full Text | References | PDF (408.9 KB) | Supplemental
  • 214 Views
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Letter
Anti-Hu-associated paraneoplastic limbic encephalitis in Hodgkin lymphoma
Muriel Laffon, Caroline Giordana, Fabien Almairac, Maxime Benchetrit & Pierre Thomas
Pages: 1433-1434
Published online: 11 Jan 2012
CitationforAnti-Hu-associated paraneoplastic limbic encephalitis in Hodgkin lymphoma | Full Text | References | PDF (241.6 KB) | Supplemental
  • 187 Views
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