Pharmaceutical Development and Technology, Volume 24, Issue 9 (2019)

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Pharmaceutical Development and Technology, Volume 24, Issue 9 (2019)

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Research Articles

Article
Elucidating spray-dried dispersion dissolution mechanisms with focused beam reflectance measurement: contribution of polymer chemistry and particle properties to performance
Clare Frances Rawlinson-Malone, Ana Patricia Ferreira, Daniel Nicholls & Sarah Nicholson
Pages: 1055-1062
Published online: 26 Jun 2019
AbstractforElucidating spray-dried dispersion dissolution mechanisms with focused beam reflectance measurement: contribution of polymer chemistry and particle properties to performance | Full Text | References | PDF (1.1 MB) | EPUB
  • 223 Views
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Article
Pegylated magnetic mesoporous silica nanoparticles decorated with AS1411 Aptamer as a targeting delivery system for cytotoxic agents
Ramin Sakhtianchi, Behrad Darvishi, Zahra Mirzaie, Farid Dorkoosh, Saeed Shanehsazzadeh & Rassoul Dinarvand
Pages: 1063-1075
Published online: 08 Aug 2019
AbstractforPegylated magnetic mesoporous silica nanoparticles decorated with AS1411 Aptamer as a targeting delivery system for cytotoxic agents | Full Text | References | PDF (2.9 MB) | EPUB
  • 331 Views
  • 31 CrossRef citations
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Article
Effect of Soluplus on the supersaturation and absorption of tacrolimus formulated as inclusion complex with dimethyl-β-cyclodextrin
Chun Tao, Taotao Huo, Qian Zhang & Hongtao Song
Pages: 1076-1082
Published online: 08 Jul 2019
AbstractforEffect of Soluplus on the supersaturation and absorption of tacrolimus formulated as inclusion complex with dimethyl-β-cyclodextrin | Full Text | References | PDF (1.5 MB) | EPUB
  • 203 Views
  • 9 CrossRef citations
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Article
Intranasal Tadalafil nanoemulsions: formulation, characterization and pharmacodynamic evaluation
Bassant Elbardisy, Sally Galal, Doaa A. Abdelmonsif & Nabila Boraie
Pages: 1083-1094
Published online: 29 Jul 2019
AbstractforIntranasal Tadalafil nanoemulsions: formulation, characterization and pharmacodynamic evaluation | Full Text | References | PDF (1.4 MB) | EPUB
  • 339 Views
  • 15 CrossRef citations
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Article
Intratumoral delivery and therapeutic efficacy of nanoparticle-encapsulated anti-tumor siRNA following intrapulmonary administration for potential treatment of lung cancer
Yukimune Kanehira, Kohei Togami, Kiyomi Ishizawa, Shingo Sato, Hitoshi Tada & Sumio Chono
Pages: 1095-1103
Published online: 27 Jun 2019
AbstractforIntratumoral delivery and therapeutic efficacy of nanoparticle-encapsulated anti-tumor siRNA following intrapulmonary administration for potential treatment of lung cancer | Full Text | References | PDF (3 MB) | EPUB
  • 204 Views
  • 6 CrossRef citations
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Article
Development and characterization of PLGA nanoparticles containing 1,3-dihydroxy-2-methylxanthone with improved antitumor activity on a human breast cancer cell line
Maribel Teixeira, Madalena Pedro, Maria São José Nascimento, Madalena M. M. Pinto & Carlos Maurício Barbosa
Pages: 1104-1114
Published online: 29 Jul 2019
AbstractforDevelopment and characterization of PLGA nanoparticles containing 1,3-dihydroxy-2-methylxanthone with improved antitumor activity on a human breast cancer cell line | Full Text | References | PDF (1.8 MB) | EPUB
  • 130 Views
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Article
Preparation and physicochemical characterization of binary and ternary ground mixtures of carvedilol with PVP and SLS aimed to improve the drug dissolution
Noushin Bolourchian, Zohreh Talamkhani & Ali Nokhodchi
Pages: 1115-1124
Published online: 29 Jul 2019
AbstractforPreparation and physicochemical characterization of binary and ternary ground mixtures of carvedilol with PVP and SLS aimed to improve the drug dissolution | Full Text | References | PDF (1.8 MB) | EPUB
  • 122 Views
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Article
Dihydroartemisinin and doxorubicin co-loaded Soluplus®-TPGS mixed micelles: formulation characterization, cellular uptake, and pharmacodynamic studies
Yutong Wang, Yanfang Ding, Jing Zhao, Changyuan Wang, Meng Gao, Xinming Chi, Baojing Zhang, Xiaodong Ma & Lei Li
Pages: 1125-1132
Published online: 02 Aug 2019
AbstractforDihydroartemisinin and doxorubicin co-loaded Soluplus®-TPGS mixed micelles: formulation characterization, cellular uptake, and pharmacodynamic studies | Full Text | References | PDF (2.4 MB) | EPUB
  • 188 Views
  • 13 CrossRef citations
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Article
Sustained release of a model water-soluble compound via dry powder aerosolizable acetalated dextran microparticles
Nishan K. Shah, Zimeng Wang, Sweta K. Gupta, Andrew Le Campion & Samantha A. Meenach
Pages: 1133-1143
Published online: 22 Jul 2019
AbstractforSustained release of a model water-soluble compound via dry powder aerosolizable acetalated dextran microparticles | Full Text | References | PDF (1.9 MB) | EPUB | Supplemental
  • 141 Views
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Article
Gel network comprising UV crosslinked PLGA-b-PEG-MA nanoparticles for ibuprofen topical delivery
Ipek Eroglu, Merve Gultekinoglu, Cem Bayram, Acelya Erikci, Samiye Yabanoglu Ciftci, Eda Ayse Aksoy & Kezban Ulubayram
Pages: 1144-1154
Published online: 08 Aug 2019
AbstractforGel network comprising UV crosslinked PLGA-b-PEG-MA nanoparticles for ibuprofen topical delivery | Full Text | References | PDF (2.1 MB) | EPUB
  • 545 Views
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Article
Development and in vivo evaluation of baicalin-loaded W/O nanoemulsion for lymphatic absorption
Qian Xu, An Zhou, Hongfei Wu & Yujie Bi
Pages: 1155-1163
Published online: 08 Aug 2019
AbstractforDevelopment and in vivo evaluation of baicalin-loaded W/O nanoemulsion for lymphatic absorption | Full Text | References | PDF (1.7 MB) | EPUB
  • 167 Views
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Article
Development and characterization of octreotide-modified curcumin plus docetaxel micelles for potential treatment of non-small-cell lung cancer
Quan An, Chen-Xiao Shi, Hao Guo, Shi-Min Xie, Ying-Ying Yang, Ying-Nan Liu, Zi-Hao Liu, Chang-Zheng Zhou & Feng-Ju Niu
Pages: 1164-1174
Published online: 08 Aug 2019
AbstractforDevelopment and characterization of octreotide-modified curcumin plus docetaxel micelles for potential treatment of non-small-cell lung cancer | Full Text | References | PDF (2.6 MB) | EPUB
  • 175 Views
  • 14 CrossRef citations
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Short Reports

Report
Two new polymorphs and one dihydrate of lenalidomide: solid-state characterization study
Lina Jia, Zhonghua Li & Junbo Gong
Pages: 1175-1180
Published online: 22 Jul 2019
AbstractforTwo new polymorphs and one dihydrate of lenalidomide: solid-state characterization study | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
  • 203 Views
  • 5 CrossRef citations
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Report
Key production parameters for the development of solid lipid nanoparticles by high shear homogenization
Eliana B. Souto, Slavomira Doktorovova, Aleksandra Zielinska & Amélia M. Silva
Pages: 1181-1185
Published online: 08 Aug 2019
AbstractforKey production parameters for the development of solid lipid nanoparticles by high shear homogenization | Full Text | References | PDF (1.3 MB) | EPUB
  • 345 Views
  • 33 CrossRef citations
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