Pharmaceutical Development and Technology, Volume 25, Issue 10 (2020)

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Pharmaceutical Development and Technology, Volume 25, Issue 10 (2020)

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Review Article

Review Article
Polyethylene oxide and its controlled release properties in hydrophilic matrix tablets for oral administration
Jigar D. Vanza, Rashmin B. Patel, Richa R. Dave & Mrunali R. Patel
Pages: 1169-1187
Published online: 20 Aug 2020
AbstractforPolyethylene oxide and its controlled release properties in hydrophilic matrix tablets for oral administration | Full Text | References | PDF (1.9 MB) | EPUB
  • 365 Views
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Short Report

Improved sensory properties of a nanostructured ritonavir suspension with a pediatric administration perspective
Germano Prebianca, Morgana Souza Marques, Mariana Domingues Bianchin, Renata Vidor Contri & Irene Clemes Külkamp-Guerreiro
Pages: 1188-1191
Published online: 25 Aug 2020
AbstractforImproved sensory properties of a nanostructured ritonavir suspension with a pediatric administration perspective | Full Text | References | PDF (588.5 KB) | EPUB
  • 109 Views
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Research Articles

Article
Surface modified nanoliposome formulations provide sustained release for 5-FU and increase cytotoxicity on A431 cell line
Ümran Yaman, Minela Aslan, Sukru Ozturk, Kezban Ulubayram & İpek Eroğlu
Pages: 1192-1203
Published online: 04 Aug 2020
AbstractforSurface modified nanoliposome formulations provide sustained release for 5-FU and increase cytotoxicity on A431 cell line | Full Text | References | PDF (2 MB) | EPUB
  • 327 Views
  • 1 CrossRef citations
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Article
Effects of process parameters on tablet critical quality attributes in continuous direct compression: a case study of integrating data-driven statistical models and mechanistic compaction models
Zhuangrong Huang, Shaun C. Galbraith, Bumjoon Cha, Huolong Liu, Seoyoung Park, Matthew H. Flamm, Matt Metzger, Anthony Tantuccio & Seongkyu Yoon
Pages: 1204-1215
Published online: 18 Aug 2020
AbstractforEffects of process parameters on tablet critical quality attributes in continuous direct compression: a case study of integrating data-driven statistical models and mechanistic compaction models | Full Text | References | PDF (3.3 MB) | EPUB
  • 380 Views
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Article
Preparation, characterization and antimicrobial activity evaluation of electrospun PCL nanofiber composites of resveratrol nanocrystals
Alptug Karakucuk & Serdar Tort
Pages: 1216-1225
Published online: 10 Aug 2020
AbstractforPreparation, characterization and antimicrobial activity evaluation of electrospun PCL nanofiber composites of resveratrol nanocrystals | Full Text | References | PDF (2.1 MB) | EPUB | Supplemental
  • 658 Views
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Article
The preparation of felodipine/zein amorphous solid dispersions and in vitro evaluation using a dynamic gastrointestinal system
Hongwei Zhang, Xu Liu & Xiangyu Ma
Pages: 1226-1237
Published online: 20 Aug 2020
AbstractforThe preparation of felodipine/zein amorphous solid dispersions and in vitro evaluation using a dynamic gastrointestinal system | Full Text | References | PDF (2.7 MB) | EPUB
  • 187 Views
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Article
New therapeutic system based on hydrogels for vaginal candidiasis management: formulation–characterization and in vitro evaluation based on vaginal irritation and direct contact test
Muhammet Davut Arpa, Ayşegül Yoltaş, Ecehan Onay Tarlan, Cemre Şahin Şenyüz, Hande Sipahi, Ahmet Aydın & Neslihan Üstündağ Okur
Pages: 1238-1248
Published online: 28 Aug 2020
AbstractforNew therapeutic system based on hydrogels for vaginal candidiasis management: formulation–characterization and in vitro evaluation based on vaginal irritation and direct contact test | Full Text | References | PDF (2.2 MB) | EPUB
  • 555 Views
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Article
Chlorin e6-loaded sonosensitive magnetic nanoliposomes conjugated with the magnetic field for enhancing anti-tumor effect of sonodynamic therapy
Hai-mei Zhu, Yi He, Su-su Huang, Jin-jie Tian, Li-sheng Wang, Jian-dong Hao, Bo Xie & Jia-jun Ling
Pages: 1249-1259
Published online: 30 Aug 2020
AbstractforChlorin e6-loaded sonosensitive magnetic nanoliposomes conjugated with the magnetic field for enhancing anti-tumor effect of sonodynamic therapy | Full Text | References | PDF (2.9 MB) | EPUB
  • 135 Views
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Article
Prediction of saxagliptin stability using a new approach based on Partial Least Squares and Design of Experiments
Nika Jordan, Jure Zakrajšek, Simona Bohanec, Robert Roškar & Iztok Grabnar
Pages: 1260-1270
Published online: 09 Sep 2020
AbstractforPrediction of saxagliptin stability using a new approach based on Partial Least Squares and Design of Experiments | Full Text | References | PDF (3.5 MB) | EPUB | Supplemental
  • 197 Views
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Article
Safety assessment of a newly synthesized copolymer for micellar delivery of hydrophobic caffeic acid phenethyl ester
Yordan Yordanov, Denitsa Aluani, Virginia Tzankova, Stanislav Rangelov, Feodor Odzhakov, Alexandar Apostolov & Krassimira Yoncheva
Pages: 1271-1280
Published online: 09 Sep 2020
AbstractforSafety assessment of a newly synthesized copolymer for micellar delivery of hydrophobic caffeic acid phenethyl ester | Full Text | References | PDF (2.2 MB) | EPUB
  • 99 Views
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Article
A surfactant-stripped cabazitaxel micelle formulation optimized with accelerated storage stability
Boyang Sun, Huang Jing, Moustafa T. Mabrouk, Yumiao Zhang, Honglin Jin & Jonathan F. Lovell
Pages: 1281-1288
Published online: 16 Sep 2020
AbstractforA surfactant-stripped cabazitaxel micelle formulation optimized with accelerated storage stability | Full Text | References | PDF (1.7 MB) | EPUB | Supplemental
  • 126 Views
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Article
Doxorubicin hydrochloride loaded nanotextured films as a novel drug delivery platform for ovarian cancer treatment
Gökçen Yaşayan, Pınar Mega Tiber, Oya Orun & Emine Alarçin
Pages: 1289-1301
Published online: 23 Sep 2020
AbstractforDoxorubicin hydrochloride loaded nanotextured films as a novel drug delivery platform for ovarian cancer treatment | Full Text | References | PDF (2.7 MB) | EPUB | Supplemental
  • 255 Views
  • 3 CrossRef citations
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Article
Development of freeze-drying cycle via design space approach: a case study on vaccines
Bernadette Scutellà & Erwan Bourlès
Pages: 1302-1313
Published online: 30 Aug 2020
AbstractforDevelopment of freeze-drying cycle via design space approach: a case study on vaccines | Full Text | References | PDF (2.3 MB) | EPUB
  • 365 Views
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