Xenobiotica, Volume 25, Issue 12 (1995)

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Xenobiotica, Volume 25, Issue 12 (1995)

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Research Article

Article
Prediction of urinary sulphate and glucuronide conjugate excretion for substituted phenols in the rat using quantitative structure-metabolism relationships
E. Holmes, B. C. Sweatman, M. E. Bollard, C. A. Blackledge, C. R. Beddell, I. D. Wilson, J. C. Lindon & J. K. Nicholson
Pages: 1269-1281
Published online: 22 Sep 2008
AbstractforPrediction of urinary sulphate and glucuronide conjugate excretion for substituted phenols in the rat using quantitative structure-metabolism relationships | References | PDF (758 KB)
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Article
S-oxidation of (+)-cis-3,5-dimethyl-2-(3-pyridyl)-thiazolidin-4-one hydrochloride by rat hepatic flavin-containing monooxygenase 1 expressed in yeast
K. Nunoya, T. Yokoi, K. Itoh, S. Itoh, K. Kimura & T. Kamataki
Pages: 1283-1291
Published online: 22 Sep 2008
AbstractforS-oxidation of (+)-cis-3,5-dimethyl-2-(3-pyridyl)-thiazolidin-4-one hydrochloride by rat hepatic flavin-containing monooxygenase 1 expressed in yeast | References | PDF (571.7 KB)
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Article
Saturable binding sites for the coenzyme A ester of nafenopin, a peroxisome proliferator, in rat liver cytosol
C. Morgan & M. Bronfman
Pages: 1293-1300
Published online: 22 Sep 2008
AbstractforSaturable binding sites for the coenzyme A ester of nafenopin, a peroxisome proliferator, in rat liver cytosol | References | PDF (533.2 KB)
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Article
Influence of partial hepatectomy in dogs on trimethadione metabolism and microsomal monooxygenases
E. Tanaka, A. Osada, A. Ishikawa, T. Nakamura, Y. Momose, T. Mikami, K. Fukao & T. Horie
Pages: 1301-1310
Published online: 22 Sep 2008
AbstractforInfluence of partial hepatectomy in dogs on trimethadione metabolism and microsomal monooxygenases | References | PDF (806.9 KB)
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Article
Stereoselective reversible ketone formation from 10-hydroxylated nortriptyline metabolites in human liver
U. Breyer-Pfaff & K. Nill
Pages: 1311-1325
Published online: 22 Sep 2008
AbstractforStereoselective reversible ketone formation from 10-hydroxylated nortriptyline metabolites in human liver | References | PDF (953.7 KB)
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Article
Metabolism of sertindole: identification of the metabolites in the rat and dog, and species comparison of liver microsomal metabolism
K. Sakamoto, Y. Nakamura, S. Aikoh, T. Baba, J. Perregaard, H. Pedersen, E. K. Moltzen, D. J. Mulford & T. Yamaguchi
Pages: 1327-1343
Published online: 22 Sep 2008
AbstractforMetabolism of sertindole: identification of the metabolites in the rat and dog, and species comparison of liver microsomal metabolism | References | PDF (989.7 KB)
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Article
Gliclazide hydroxylation by rat liver microsomes
A. Rieutord, I. Stupans, G. M. Shenfield & A. S. Gross
Pages: 1345-1354
Published online: 22 Sep 2008
AbstractforGliclazide hydroxylation by rat liver microsomes | References | PDF (672.2 KB)
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Article
Molecular orbital-generated QSARs in a homologous series of alkoxyresorufins and studies of their interactive docking with P450s
D. F. V. Lewis, B. G. Lake & D. V. Parke
Pages: 1355-1369
Published online: 22 Sep 2008
AbstractforMolecular orbital-generated QSARs in a homologous series of alkoxyresorufins and studies of their interactive docking with P450s | References | PDF (809.7 KB)
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Article
Pharmacokinetics of the 5-hydroxytryptamine1A agonist 8-hydroxy-2-(N,N-di-n-propylamino)tetralin (8-OHDPAT) in the rat after intravenous and oral administration
J. P. Mason, L. G. Dring & J. Caldwell
Pages: 1371-1380
Published online: 22 Sep 2008
AbstractforPharmacokinetics of the 5-hydroxytryptamine1A agonist 8-hydroxy-2-(N,N-di-n-propylamino)tetralin (8-OHDPAT) in the rat after intravenous and oral administration | References | PDF (530.7 KB)
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Article
Bosentan, a new endothelin receptor antagonist: prediction of the systemic plasma clearance in man from combined in vivo and in vitro data
G. Ubeaud, C. Schmitt, D. Jaeck, T. Lave & Ph. Coassolo
Pages: 1381-1390
Published online: 22 Sep 2008
AbstractforBosentan, a new endothelin receptor antagonist: prediction of the systemic plasma clearance in man from combined in vivo and in vitro data | References | PDF (663.1 KB)
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Article
Fate of dipropyl sulphone in rat
R. M. Nickson, S. C. Mitchell & A. Q. Zhang
Pages: 1391-1398
Published online: 22 Sep 2008
AbstractforFate of dipropyl sulphone in rat | References | PDF (611.1 KB)
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Article
Role of cytochrome P450 in hydrazine toxicity in isolated hepatocytes in vitro
J. Delaney & J. A. Timbrell
Pages: 1399-1410
Published online: 22 Sep 2008
AbstractforRole of cytochrome P450 in hydrazine toxicity in isolated hepatocytes in vitro | References | PDF (665.4 KB)
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