Xenobiotica, Volume 33, Issue 1 (2003)

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Xenobiotica, Volume 33, Issue 1 (2003)

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Research Article

Article
4-Biphenylaldehyde and 9-anthraldehyde: two fluorescent substrates for determining P450 enzyme activities in rat and human
S. Marini, E. Grasso, V. Longo, P. Puccini, B. Riccardi & P. Giovanni Gervasi
Pages: 1-11
Published online: 22 Sep 2008
Abstractfor4-Biphenylaldehyde and 9-anthraldehyde: two fluorescent substrates for determining P450 enzyme activities in rat and human | References | PDF (169.7 KB)
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Article
Role of specific cytochrome P450 enzymes in the N-oxidation of the antiarrhythmic agent mexiletine
L. LabbÈ, Z. Abolfathi, È. Lessard, H. Pakdel, P. Beaune & J. Turgeon
Pages: 13-25
Published online: 22 Sep 2008
AbstractforRole of specific cytochrome P450 enzymes in the N-oxidation of the antiarrhythmic agent mexiletine | References | PDF (145.4 KB)
  • 106 Views
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Article
Metabolic fate of pitavastatin, a new inhibitor of HMG-CoA reductase: human UDP-glucuronosyltransferase enzymes involved in lactonization
H. Fujino, I. Yamada, S. Shimada, M. Yoneda & J. Kojima
Pages: 27-41
Published online: 22 Sep 2008
AbstractforMetabolic fate of pitavastatin, a new inhibitor of HMG-CoA reductase: human UDP-glucuronosyltransferase enzymes involved in lactonization | References | PDF (245.4 KB)
  • 426 Views
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Article
Catalytic activities of cytochrome P450 enzymes and UDP-glucuronosyltransferases involved in drug metabolism in rat everted sacs and intestinal microsomes
K. Takemoto, H. Yamazaki, Y. Tanaka, M. Nakajima & T. Yokoi
Pages: 43-55
Published online: 22 Sep 2008
AbstractforCatalytic activities of cytochrome P450 enzymes and UDP-glucuronosyltransferases involved in drug metabolism in rat everted sacs and intestinal microsomes | References | PDF (159.5 KB)
  • 140 Views
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Article
Studies on the inhibition of human cytochromes P450 by selenocysteine Se -conjugates
J. Venhorst, M. Rooseboom, N. P. E. Vermeulen & J. N. M. Commandeur
Pages: 57-72
Published online: 22 Sep 2008
AbstractforStudies on the inhibition of human cytochromes P450 by selenocysteine Se -conjugates | References | PDF (251.5 KB)
  • 51 Views
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Article
CYP2A13-catalysed coumarin metabolism: comparison with CYP2A5 and CYP2A6
L. B. VON WEYMARN & S. E. MURPHY
Pages: 73-81
Published online: 22 Sep 2008
AbstractforCYP2A13-catalysed coumarin metabolism: comparison with CYP2A5 and CYP2A6 | References | PDF (192.5 KB)
  • 161 Views
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Article
Sulphoxidation of ethyl methyl sulphide, 4-chlorophenyl methyl sulphide and diphenyl sulphide by purified pig liver flavin-containing monooxygenase
I. P. Nnane & L. A. Damani
Pages: 83-91
Published online: 22 Sep 2008
AbstractforSulphoxidation of ethyl methyl sulphide, 4-chlorophenyl methyl sulphide and diphenyl sulphide by purified pig liver flavin-containing monooxygenase | References | PDF (133.8 KB)
  • 22 Views
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Article
Oxidative activation of acylguanidine prodrugs: intestinal presystemic activation in rats limits absorption and can be inhibited by co-administration of ketoconazole
W. G. Humphreys, M. T. Obermeier, S. Chong, S. D. Kimball, J. Das, P. Chen, R. Moquin, W.-C. Han, R. Gedamke, R. E. White & R. A. Morrison
Pages: 93-106
Published online: 22 Sep 2008
AbstractforOxidative activation of acylguanidine prodrugs: intestinal presystemic activation in rats limits absorption and can be inhibited by co-administration of ketoconazole | References | PDF (232.1 KB)
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