Xenobiotica, Volume 37, Issue 1 (2007)

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Xenobiotica, Volume 37, Issue 1 (2007)

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Research Article

Article
Effects of ertiprotafib on hepatic cytochrome P450 and peroxisomal enzymes in rats and dogs, and in rat and human primary hepatocytes
Z. Tong, A. Chandrasekaran, R. Jordan, V. Markiewicz, H. Li, Q. Xiang, L. Shen & J. Scatina
Pages: 1-18
Published online: 22 Sep 2008
AbstractforEffects of ertiprotafib on hepatic cytochrome P450 and peroxisomal enzymes in rats and dogs, and in rat and human primary hepatocytes | Full Text | References | PDF (127.8 KB)
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Article
Inhibition and recovery of maternal and foetal cholinesterase enzymes following fenitrothion administration in CD rats
M. A. Sochaski, B. M. McManus, M. F. Struve, D. G. Wallace & D. C. Dorman
Pages: 19-29
Published online: 22 Sep 2008
AbstractforInhibition and recovery of maternal and foetal cholinesterase enzymes following fenitrothion administration in CD rats | Full Text | References | PDF (257.2 KB)
  • 49 Views
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Article
CYP2C76-mediated species difference in drug metabolism: A comparison of pitavastatin metabolism between monkeys and humans
Y. Uno, T. Kumano, G. Kito, R. Nagata, T. Kamataki & H. Fujino
Pages: 30-43
Published online: 22 Sep 2008
AbstractforCYP2C76-mediated species difference in drug metabolism: A comparison of pitavastatin metabolism between monkeys and humans | Full Text | References | PDF (105 KB)
  • 191 Views
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Article
Metabolism of [14C]-5-chloro-1,3-benzodioxol-4-amine in male Wistar-derived rats following intraperitoneal administration
T. J. Athersuch, C. J. Duckett, J. Castro-Perez, C. Rodgers, J. K. Nicholson & I. D. Wilson
Pages: 44-58
Published online: 22 Sep 2008
AbstractforMetabolism of [14C]-5-chloro-1,3-benzodioxol-4-amine in male Wistar-derived rats following intraperitoneal administration | Full Text | References | PDF (466.2 KB)
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Article
Stereoselective pharmacokinetics of oxybutynin and N-desethyloxybutynin in vitro and in vivo
H. Mizushima, K. Takanaka, K. Abe, I. Fukazawa & H. Ishizuka
Pages: 59-73
Published online: 22 Sep 2008
AbstractforStereoselective pharmacokinetics of oxybutynin and N-desethyloxybutynin in vitro and in vivo | Full Text | References | PDF (136.2 KB)
  • 216 Views
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Article
Pharmacokinetic study of darbepoetin alfa: Absorption, distribution, and excretion after a single intravenous and subcutaneous administration to rats
E. Yoshioka, K. Kato, H. Shindo, C. Mitsuoka, S.-I. Kitajima, H. Ogata & T. Misaizu
Pages: 74-90
Published online: 22 Sep 2008
AbstractforPharmacokinetic study of darbepoetin alfa: Absorption, distribution, and excretion after a single intravenous and subcutaneous administration to rats | Full Text | References | PDF (335.4 KB)
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Original

Article
Prediction of pharmacokinetics of CS-023 (RO4908463), a novel parenteral carbapenem antibiotic, in humans using animal data
T. Shibayama, Y. Matsushita, A. Kurihara, T. Hirota & T. Ikeda
Pages: 91-102
Published online: 12 Jul 2010
AbstractforPrediction of pharmacokinetics of CS-023 (RO4908463), a novel parenteral carbapenem antibiotic, in humans using animal data | Full Text | References | PDF (150.1 KB)
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Research Article

Article
Genetic polymorphisms involved in toxicant-metabolizing enzymes and the risk of chronic benzene poisoning in Chinese occupationally exposed populations
Y. Chen, G. Li, S. Yin, J. Xu, Z. Ji, X. Xiu, L. Liu & D. Ma
Pages: 103-112
Published online: 22 Sep 2008
AbstractforGenetic polymorphisms involved in toxicant-metabolizing enzymes and the risk of chronic benzene poisoning in Chinese occupationally exposed populations | Full Text | References | PDF (67 KB)
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