Xenobiotica, Volume 37, Issue 3 (2007)

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Xenobiotica, Volume 37, Issue 3 (2007)

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Research Article

Article
AmineDB: Large scale docking of amines with CYP2D6 and scoring for druglike properties—towards defining the scope of the chemical defense against foreign amines in humans
A. D. Costache, D. Trawick, D. Bohl & D. S. Sem
Pages: 221-245
Published online: 22 Sep 2008
AbstractforAmineDB: Large scale docking of amines with CYP2D6 and scoring for druglike properties—towards defining the scope of the chemical defense against foreign amines in humans | Full Text | References | PDF (1.5 MB)
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Article
Characterization of cytochrome P450s mediating ipriflavone metabolism in human liver microsomes
Y. Moon, S. Y. Kim, H. Y. Ji, Y. K. Kim, H.-J. Chae, S.-W. Chae & H. S. Lee
Pages: 246-259
Published online: 22 Sep 2008
AbstractforCharacterization of cytochrome P450s mediating ipriflavone metabolism in human liver microsomes | Full Text | References | PDF (123.9 KB)
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Article
Nafamostat is hydrolysed by human liver cytosolic long-chain acyl-CoA hydrolase
S. Yamaori, E. Ukena, N. Fujiyama, T. Funahashi, T. Kimura, I. Yamamoto, T. Ohshima, K. Matsumura, M. Oda & K. Watanabe
Pages: 260-270
Published online: 22 Sep 2008
AbstractforNafamostat is hydrolysed by human liver cytosolic long-chain acyl-CoA hydrolase | Full Text | References | PDF (94.6 KB)
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Article
Identification of novel dioxin-responsive genes by representational difference analysis
S. P. Rivera, S. T. Saarikoski, W. Sun & O. Hankinson
Pages: 271-279
Published online: 22 Sep 2008
AbstractforIdentification of novel dioxin-responsive genes by representational difference analysis | Full Text | References | PDF (165.9 KB)
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Article
In vitro metabolite identification of ML3403, a 4-pyridinylimidazole-type p38 MAP kinase inhibitor by LC-Qq-TOF-MS and LC-SPE-cryo-NMR/MS
B. Kammerer, H. Scheible, G. Zurek, M. Godejohann, K.-P. Zeller, C. H. Gleiter, W. Albrecht & S. Laufer
Pages: 280-297
Published online: 22 Sep 2008
AbstractforIn vitro metabolite identification of ML3403, a 4-pyridinylimidazole-type p38 MAP kinase inhibitor by LC-Qq-TOF-MS and LC-SPE-cryo-NMR/MS | Full Text | References | PDF (300.6 KB)
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Article
The pharmacokinetics and tissue distribution of the glucosylceramide synthase inhibitor miglustat in the rat
A. Treiber, O. Morand & M. Clozel
Pages: 298-314
Published online: 22 Sep 2008
AbstractforThe pharmacokinetics and tissue distribution of the glucosylceramide synthase inhibitor miglustat in the rat | Full Text | References | PDF (158.9 KB)
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Article
Association of CYP3A4*18B polymorphisms with the pharmacokinetics of cyclosporine in healthy subjects
Y.-F. Hu, J.-H. Tu, Z.-R. Tan, Z.-Q. Liu, G. Zhou, J. He, D. Wang & H.-H. Zhou
Pages: 315-327
Published online: 22 Sep 2008
AbstractforAssociation of CYP3A4*18B polymorphisms with the pharmacokinetics of cyclosporine in healthy subjects | Full Text | References | PDF (94.2 KB)
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Article
Distribution of radioactivity and metabolite profiling in tumour and plasma following intravenous administration of a colchicine derivative (14C-ZD6126) to tumour-bearing mice
R. A. D'Souza, E. A. Partridge, D. W. Roberts, S. Ashton, A. Ryan, A. B. Patterson, Z. Wilson & C. C. Thurrell
Pages: 328-340
Published online: 22 Sep 2008
AbstractforDistribution of radioactivity and metabolite profiling in tumour and plasma following intravenous administration of a colchicine derivative (14C-ZD6126) to tumour-bearing mice | Full Text | References | PDF (162.5 KB)
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