Xenobiotica, Volume 37, Issue 8 (2007)

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Xenobiotica, Volume 37, Issue 8 (2007)

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Research Article

Article
In vitro metabolism of eupatilin by multiple cytochrome P450 and UDP-glucuronosyltransferase enzymes
H. S. Lee, H. Y. Ji, E. J. Park & S. Y. Kim
Pages: 803-817
Published online: 22 Sep 2008
AbstractforIn vitro metabolism of eupatilin by multiple cytochrome P450 and UDP-glucuronosyltransferase enzymes | Full Text | References | PDF (252.6 KB)
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Article
Functional involvement of organic cation transporter1 (OCT1/Oct1) in the hepatic uptake of organic cations in humans and rats
K.-I. Umehara, T. Iwatsubo, K. Noguchi & H. Kamimura
Pages: 818-831
Published online: 22 Sep 2008
AbstractforFunctional involvement of organic cation transporter1 (OCT1/Oct1) in the hepatic uptake of organic cations in humans and rats | Full Text | References | PDF (125.1 KB)
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Article
The metabolism of the 5HT3 antagonists ondansetron, alosetron and GR87442 I: A comparison of in vitro and in vivo metabolism and in vitro enzyme kinetics in rat, dog and human hepatocytes, microsomes and recombinant human enzymes
G. I. Somers, A. J. Harris, M. K. Bayliss & J. B. Houston
Pages: 832-854
Published online: 22 Sep 2008
AbstractforThe metabolism of the 5HT3 antagonists ondansetron, alosetron and GR87442 I: A comparison of in vitro and in vivo metabolism and in vitro enzyme kinetics in rat, dog and human hepatocytes, microsomes and recombinant human enzymes | Full Text | References | PDF (161.7 KB)
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Article
The metabolism of the 5HT3 antagonists, ondansetron, alosetron and GR87442 II: Investigation into the in vitro methods used to predict the in vivo hepatic clearance of ondansetron, alosetron and GR87442 in the rat, dog and human
G. I. Somers, M. K. Bayliss & J. B. Houston
Pages: 855-869
Published online: 22 Sep 2008
AbstractforThe metabolism of the 5HT3 antagonists, ondansetron, alosetron and GR87442 II: Investigation into the in vitro methods used to predict the in vivo hepatic clearance of ondansetron, alosetron and GR87442 in the rat, dog and human | Full Text | References | PDF (107.7 KB)
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Article
Use of Freund's Complete Adjuvant (FCA) in inflammatory pain models: Consequences on the metabolism and pharmacokinetics of the non-peptidic delta receptor agonist SNC80 in the rat
D. Projean PhD, E. Lessard, M. P. Ducharme & J. Ducharme
Pages: 870-883
Published online: 22 Sep 2008
AbstractforUse of Freund's Complete Adjuvant (FCA) in inflammatory pain models: Consequences on the metabolism and pharmacokinetics of the non-peptidic delta receptor agonist SNC80 in the rat | Full Text | References | PDF (100.3 KB)
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Article
Disposition and metabolic fate of prasugrel in mice, rats, and dogs
R. L. Smith, T. A. Gillespie, T. J. Rash, A. Kurihara & N. A. Farid
Pages: 884-901
Published online: 22 Sep 2008
AbstractforDisposition and metabolic fate of prasugrel in mice, rats, and dogs | Full Text | References | PDF (423.1 KB)
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