Xenobiotica, Volume 48, Issue 1 (2018)

Browse this journal
Sample our Medicine, Dentistry, Nursing & Allied Health journals, sign in here to start your FREE access for 14 days

Xenobiotica, Volume 48, Issue 1 (2018)

See all volumes and issues
Vol 54, 2024 Vol 53, 2023 Vol 52, 2022 Vol 51, 2021 Vol 50, 2020 Vol 49, 2019 Volume 48, 2018 Vol 47, 2017 Vol 46, 2016 Vol 45, 2015 Vol 44, 2014 Vol 43, 2013 Vol 42, 2012 Vol 41, 2011 Vol 40, 2010 Vol 39, 2009 Vol 38, 2008 Vol 37, 2007 Vol 36, 2006 Vol 35, 2005 Vol 34, 2004 Vol 33, 2003 Vol 32, 2002 Vol 31, 2001 Vol 30, 2000 Vol 29, 1999 Vol 28, 1998 Vol 27, 1997 Vol 26, 1996 Vol 25, 1995 Vol 24, 1994 Vol 23, 1993 Vol 22, 1992 Vol 21, 1991 Vol 20, 1990 Vol 19, 1989 Vol 18, 1988 Vol 17, 1987 Vol 16, 1986 Vol 15, 1985 Vol 14, 1984 Vol 13, 1983 Vol 12, 1982 Vol 11, 1981 Vol 10, 1980 Vol 9, 1979 Vol 8, 1978 Vol 7, 1977 Vol 6, 1976 Vol 5, 1975 Vol 4, 1974 Vol 3, 1973 Vol 2, 1972 Vol 1, 1971
Download citations Download PDFs Download issue

General Xenobiochemistry

Article
Consequences of daily corticosteroid dosing with or without pre-treatment with quinidine on the in vivo cytochrome P450 2D (CYP2D) enzyme in rats: effect on O-demethylation activity of dextromethorphan and expression levels of CYP2D1 mRNA
Poonam Giri, Prashant Delvadia, Laxmikant Gupta, Nirmal Patel, Priyal Trivedi, Krishna Lad, Hiren M. Patel & Nuggehally R. Srinivas
Pages: 1-10
Published online: 19 Jan 2017
AbstractforConsequences of daily corticosteroid dosing with or without pre-treatment with quinidine on the in vivo cytochrome P450 2D (CYP2D) enzyme in rats: effect on O-demethylation activity of dextromethorphan and expression levels of CYP2D1 mRNA | Full Text | References | PDF (775.2 KB)
  • 180 Views
  • 2 CrossRef citations
  • 0Altmetric

Animal Pharmacokinetics and Metabolism

Article
Two sulfonate metabolites of physalin A in rats
Hongxia Liu, Kai Wang, Guiyang Xia, Kun Wang, Liwei Chai, Paul Owusu Donkor, Liqin Ding & Feng Qiu
Pages: 11-17
Published online: 08 Feb 2017
AbstractforTwo sulfonate metabolites of physalin A in rats | Full Text | References | PDF (981.1 KB) | Supplemental
  • 134 Views
  • 6 CrossRef citations
  • 0Altmetric
Article
Comparative pharmacokinetics between madecassoside and asiaticoside presented in a standardised extract of Centella asiatica, ECa 233 and their respective pure compound given separately in rats
Patcharaporn Hengjumrut, Tosapol Anukunwithaya, Mayuree H. Tantisira, Boonyong Tantisira & Phisit Khemawoot
Pages: 18-27
Published online: 18 Jan 2017
AbstractforComparative pharmacokinetics between madecassoside and asiaticoside presented in a standardised extract of Centella asiatica, ECa 233 and their respective pure compound given separately in rats | Full Text | References | PDF (635.7 KB)
  • 670 Views
  • 20 CrossRef citations
  • 0Altmetric
Article
Pharmacokinetics and tissue distribution of crotonoside
Peiao Yan, Lan Zhang, Cheng Peng & Ruoqi Zhang
Pages: 28-36
Published online: 19 Jan 2017
AbstractforPharmacokinetics and tissue distribution of crotonoside | Full Text | References | PDF (1.1 MB)
  • 205 Views
  • 9 CrossRef citations
  • 0Altmetric
Article
Influence of acute and chronic kidney failure in rats on the disposition and pharmacokinetics of ZYAN1, a novel prolyl hydroxylase inhibitor, for the treatment of chronic kidney disease-induced anemia
Harilal Patel, Amit Arvind Joharapurkar, Vrajesh Bhaskarbhai Pandya, Vishal Jagjivanbhai Patel, Samadhan Govind Kshirsagar, Prakash Patel, Bhavesh Gevriya, Mukul R. Jain, Nuggehally R. Srinivas, Pankaj Ramanbhai Patel & Ranjit C. Desai
Pages: 37-44
Published online: 19 Jan 2017
AbstractforInfluence of acute and chronic kidney failure in rats on the disposition and pharmacokinetics of ZYAN1, a novel prolyl hydroxylase inhibitor, for the treatment of chronic kidney disease-induced anemia | Full Text | References | PDF (298.4 KB)
  • 286 Views
  • 8 CrossRef citations
  • 0Altmetric
Article
Pharmacokinetic interaction of aconitine, liquiritin and 6-gingerol in a traditional Chinese herbal formula, Sini Decoction
Sen Sun, Qingshan Chen, Jiyun Ge, Xiang Liu, Xinxia Wang, Qi Zhan, Hai Zhang & Guoqing Zhang
Pages: 45-52
Published online: 25 Jan 2017
AbstractforPharmacokinetic interaction of aconitine, liquiritin and 6-gingerol in a traditional Chinese herbal formula, Sini Decoction | Full Text | References | PDF (701.1 KB)
  • 252 Views
  • 8 CrossRef citations
  • 0Altmetric
Article
Altered tolbutamide pharmacokinetics by a decrease in hepatic expression of CYP2C6/11 in rats pretreated with 5-fluorouracil
Shuhei Fukuno, Katsuhito Nagai, Keita Kasahara, Yuki Mizobata, Sachiko Omotani, Yasutoshi Hatsuda, Michiaki Myotoku & Hiroki Konishi
Pages: 53-59
Published online: 31 Jan 2017
AbstractforAltered tolbutamide pharmacokinetics by a decrease in hepatic expression of CYP2C6/11 in rats pretreated with 5-fluorouracil | Full Text | References | PDF (575.5 KB)
  • 155 Views
  • 6 CrossRef citations
  • 0Altmetric

Molecular Toxicology

Article
Contributions of caspase-8 and -9 to liver injury from CYP2E1-produced metabolites of halogenated hydrocarbons
Yoshio Ijiri, Ryuji Kato, Maiko Sadamatsu, Mina Takano, Yuki Yasuda, Fumiaki Tanaka, Chiyo Oishi, Hideki Imano, Yoshikatsu Okada, Kazuhiko Tanaka & Tetsuya Hayashi
Pages: 60-72
Published online: 12 Jan 2017
AbstractforContributions of caspase-8 and -9 to liver injury from CYP2E1-produced metabolites of halogenated hydrocarbons | Full Text | References | PDF (1.5 MB)
  • 241 Views
  • 6 CrossRef citations
  • 0Altmetric

Xenobiotic Transporters

Article
Interactions of crizotinib and gefitinib with organic anion-transporting polypeptides (OATP)1B1, OATP1B3 and OATP2B1: gefitinib shows contradictory interaction with OATP1B3
Toshihiro Sato, Hajime Ito, Ayaka Hirata, Takaaki Abe, Nariyasu Mano & Hiroaki Yamaguchi
Pages: 73-78
Published online: 12 Jan 2017
AbstractforInteractions of crizotinib and gefitinib with organic anion-transporting polypeptides (OATP)1B1, OATP1B3 and OATP2B1: gefitinib shows contradictory interaction with OATP1B3 | Full Text | References | PDF (577.6 KB)
  • 455 Views
  • 13 CrossRef citations
  • 0Altmetric

Pharmacogenetics

Article
A high frequency missense SULT1B1 allelic variant (L145V) selectively expressed in African descendants exhibits altered kinetic properties
Zachary E. Tibbs, Amber L. Guidry, Josie L. Falany, Susan A. Kadlubar & Charles N. Falany
Pages: 79-88
Published online: 05 Feb 2017
AbstractforA high frequency missense SULT1B1 allelic variant (L145V) selectively expressed in African descendants exhibits altered kinetic properties | Full Text | References | PDF (672 KB) | Supplemental
  • 177 Views
  • 5 CrossRef citations
  • 0Altmetric

Topics in Xenobiochemistry

Review
Reappraisal and perspectives of clinical drug–drug interaction potential of α-glucosidase inhibitors such as acarbose, voglibose and miglitol in the treatment of type 2 diabetes mellitus
Ranjeet Prasad Dash, R. Jayachandra Babu & Nuggehally R. Srinivas
Pages: 89-108
Published online: 19 Jan 2017
AbstractforReappraisal and perspectives of clinical drug–drug interaction potential of α-glucosidase inhibitors such as acarbose, voglibose and miglitol in the treatment of type 2 diabetes mellitus | Full Text | References | PDF (342 KB)
  • 513 Views
  • 45 CrossRef citations
  • 0Altmetric

Explore articles