Cancer Biology & Therapy, Volume 6, Issue 10 (2007)

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Cancer Biology & Therapy, Volume 6, Issue 10 (2007)

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Editor's Corner

Editorial
Cover Image
Page: i
Published online: 01 Oct 2007
AbstractforCover Image | PDF (792.2 KB)
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News

News
p53 Responds to Blocked Transcription
Page: 1516
Published online: 01 Oct 2007
Abstractforp53 Responds to Blocked Transcription | PDF (90.5 KB)
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News
Targeting brain tumor stem cells extends mouse survival
Pages: 1516-1517
Published online: 01 Oct 2007
AbstractforTargeting brain tumor stem cells extends mouse survival | PDF (90.5 KB)
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News
HIPPO-Yap, cell size and cancer therapy
Pages: 1516-1517
Published online: 01 Oct 2007
AbstractforHIPPO-Yap, cell size and cancer therapy | PDF (90.5 KB)
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News
BioCurex and Abbott Jointly Present RECAF Results at International Cancer Congress
Page: 1516
Published online: 01 Oct 2007
AbstractforBioCurex and Abbott Jointly Present RECAF Results at International Cancer Congress | PDF (90.5 KB)
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News
Cedars-Sinai's Beth Karlan, M.D., Named Editor-in-Chief of Society of Gynecologic Oncologists' Medical Journal
Page: 1516
Published online: 01 Oct 2007
AbstractforCedars-Sinai's Beth Karlan, M.D., Named Editor-in-Chief of Society of Gynecologic Oncologists' Medical Journal | PDF (90.5 KB)
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News
Association of American Cancer Institutes Elects Caligiuri
Page: 1516
Published online: 01 Oct 2007
AbstractforAssociation of American Cancer Institutes Elects Caligiuri | PDF (90.5 KB)
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Journal Club

Prostaglandin E2: At the crossroads between stem cell development, Inflammation and cancer
Caitlin Marie Logan, Antonio Giordano, Andrew Puca & Marco Cassone
Pages: 1517-1520
Published online: 01 Oct 2007
AbstractforProstaglandin E2: At the crossroads between stem cell development, Inflammation and cancer | PDF (102 KB)
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Following the tracks of AKT1 gene
Paraskevi Vogiatzi & Antonio Giordano
Pages: 1521-1524
Published online: 01 Oct 2007
AbstractforFollowing the tracks of AKT1 gene | PDF (186.7 KB)
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Bedside to Bench Report

Article
Childhood ALL and second neoplasms
Tapan N. Maniar, Inbal Braunstein, Stephen Keefe, Sofia Hussen, Tara Abrams, Angela De Michele & Wafik S. El-Deiry
Pages: 1525-1531
Published online: 01 Oct 2007
AbstractforChildhood ALL and second neoplasms | PDF (308.3 KB)
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Research Paper

Article
Identification of Candidate Biomarkers for Hepatocellular Carcinoma Through Pre-Cancerous Expression Analysis in an HBx Transgenic Mouse
Qiang Sun, Yingai Zhang, Fang Liu, Xiaohang Zhao & Xiao Yang
Pages: 1532-1538
Published online: 01 Oct 2007
AbstractforIdentification of Candidate Biomarkers for Hepatocellular Carcinoma Through Pre-Cancerous Expression Analysis in an HBx Transgenic Mouse | PDF (674.7 KB)
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Article
CIAPIN1 inhibits gastric cancer cell proliferation and cell cycle progression by downregulating cyclyinD1 and upregulating p27
Xiaohua Li, Zhiming Hao, Rui Fan, Xue Zou, Haifeng Jin, Yanglin Pan, Lijie He, Rui Du, Lin Gao, Jie Liu & Daiming Fan
Pages: 1539-1545
Published online: 01 Oct 2007
AbstractforCIAPIN1 inhibits gastric cancer cell proliferation and cell cycle progression by downregulating cyclyinD1 and upregulating p27 | PDF (576.6 KB)
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Article
Evaluation of GATA-4 and GATA-5 methylation profiles in human pancreatic cancers indicate promoter methylation patterns distinct from other human tumor types
Baojin Fu, Mingzhou Guo, Shelun Wang, Domenico Campagna, Mingde Luo, James G. Herman & Christine A. Iacobuzio-Donahue
Pages: 1546-1552
Published online: 01 Oct 2007
AbstractforEvaluation of GATA-4 and GATA-5 methylation profiles in human pancreatic cancers indicate promoter methylation patterns distinct from other human tumor types | PDF (527.4 KB)
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Article
Influence of apoptosis (BCL2, FAS), Cell cycle (CCND1) and growth factor (EGF, EGFR) genetic polymorphisms on survival outcome: An exploratory study in squamous cell esophageal cancer
Meenu Jain, Rohit Upadhyay, Shaleen Kumar, Puneeta Lal, Anu Tiwari, Uday C. Ghoshal & Balraj Mittal
Pages: 1553-1558
Published online: 01 Oct 2007
AbstractforInfluence of apoptosis (BCL2, FAS), Cell cycle (CCND1) and growth factor (EGF, EGFR) genetic polymorphisms on survival outcome: An exploratory study in squamous cell esophageal cancer | PDF (262.6 KB)
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Article
A naturally occurring truncated β3 integrin in tumor cells: Native anti-integrin involved in tumor cell motility
Rongxian Jin, Mohit Trikha, Yinlong Cai, David Grignon & Kenneth V. Honn
Pages: 1559-1568
Published online: 01 Oct 2007
AbstractforA naturally occurring truncated β3 integrin in tumor cells: Native anti-integrin involved in tumor cell motility | PDF (1.2 MB)
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Article
Tumor COX-2 expression and prognosis of patients with resectable pancreatic cancer
Hiroyuki Matsubayashi, Jeffrey R. Infante, Jordan M. Winter, Alison P. Klein, Richard Schulick, Ralph Hruban, Kala Visvanathan, Kala Visvanathan & Michael Goggins
Pages: 1569-1575
Published online: 01 Oct 2007
AbstractforTumor COX-2 expression and prognosis of patients with resectable pancreatic cancer | PDF (322.4 KB)
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Article
The tetramerization domain of p53 is required for efficient BAK oligomerization
E. Christine Pietsch, J. I-Ju Leu, Amanda K. Frank, Patrick Dumont, Donna L. George & Maureen E. Murphy
Pages: 1576-1583
Published online: 01 Oct 2007
AbstractforThe tetramerization domain of p53 is required for efficient BAK oligomerization | PDF (485.5 KB)
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Article
The pilot study of anti-tumor effects versus immunosuppression of staphylococcal enterotoxin C
Ke-Ge Jie, Hua Jiang, Lei Sun, Hai-Rong Wang, Yu-Ling Zheng, Yong-Qiang Jiang & Yi Li
Pages: 1584-1591
Published online: 01 Oct 2007
AbstractforThe pilot study of anti-tumor effects versus immunosuppression of staphylococcal enterotoxin C | PDF (432.3 KB)
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Article
Copy-number variants in patients with a strong family history of pancreatic cancer
Robert Lucito, Shubha Suresh, Kimberly Walter, Akhilesh Pandey, B. Lakshmi, Alex Krasnitz, Jonathan Sebat, Michael Wigler, Alison P. Klein, Kieran Brune, Emily Palmisano, Anirban Maitra, Michael Goggins & Ralph H. Hruban
Pages: 1592-1599
Published online: 01 Oct 2007
AbstractforCopy-number variants in patients with a strong family history of pancreatic cancer | PDF (150.8 KB)
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Article
Human recombinant erythropoietin does not promote cancer growth in presence of functional receptors expressed in cancer cells
Cristóbal Belda-Iniesta, Rosario Perona, Javier de Castro Carpeño, Paloma Cejas, Enrique Casado, Cristina Manguan-García, Inmaculada Ibanez de Caceres, Isabel Sanchez-Perez, Francisco Bernabeu Andreu, Javier Alves Ferreira, Alfredo Aguilera, Javier de la Peña, Elia Perez-Sánchez, Rosario Madero, Jaime Feliu, María Sereno & Manuel González-Barón
Pages: 1600-1605
Published online: 01 Oct 2007
AbstractforHuman recombinant erythropoietin does not promote cancer growth in presence of functional receptors expressed in cancer cells | PDF (321.3 KB)
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Article
Carnitine palmitoyltransferase I in human carcinomas: A novel role in histone deacetylation?
Paola Mazzarelli, Sabina Pucci, Elena Bonanno, Fabiola Sesti, Menotti Calvani & Luigi Giusto Spagnoli
Pages: 1606-1613
Published online: 01 Oct 2007
AbstractforCarnitine palmitoyltransferase I in human carcinomas: A novel role in histone deacetylation? | PDF (601.3 KB)
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Article
c-FLIP downregulation contributes to apoptosis induction by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate (CDDO-Me) in human lung cancer cells
Wei Zou, Shuzhen Chen, Xiangguo Liu, Ping Yue, Michael B. Sporn, Fadlo R. Khuri & Shi-Yong Sun
Pages: 1614-1620
Published online: 01 Oct 2007
Abstractforc-FLIP downregulation contributes to apoptosis induction by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate (CDDO-Me) in human lung cancer cells | PDF (540.1 KB)
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Article
Suppression of azoxymethane-induced colon cancer development in rats by dietary resistant starch
Richard K. Le Leu, Ian L Brown, Ying Hu, Adrian Esterman & Graeme P. Young
Pages: 1621-1626
Published online: 01 Oct 2007
AbstractforSuppression of azoxymethane-induced colon cancer development in rats by dietary resistant starch | PDF (214.7 KB)
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Article
Novel splice isoforms of STRADα differentially affect LKB1 activity, complex assembly and subcellular localization.
Paola A. Marignani, Kristine Scott, Rosanna Bagnulo, Domenico Cannone, Eleonora Ferrari, Alessandro Stella, Ginevra Guanti, Cristiano Simone & Nicoletta Resta
Pages: 1627-1631
Published online: 01 Oct 2007
AbstractforNovel splice isoforms of STRADα differentially affect LKB1 activity, complex assembly and subcellular localization. | PDF (489.3 KB)
  • 392 Views
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Article
Pre-clinical evaluation of 1-nitroacridine derived chemotherapeutic agent that has preferential cytotoxic activity towards prostate cancer
Kiranmayi Tadi, Badithe T. Ashok, Yuangen Chen, Debabrata Banerjee, Barbara Wysocka-Skrzela, Jerzy Konopa, Zbigniew Darzynkiewicz & Raj K. Tiwari
Pages: 1632-1637
Published online: 01 Oct 2007
AbstractforPre-clinical evaluation of 1-nitroacridine derived chemotherapeutic agent that has preferential cytotoxic activity towards prostate cancer | PDF (374.4 KB)
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Article
Aberrant activation of γ-catenin promotes genomic instability and oncogenic effects during tumor progression
Hongjie Pan, Fangming Gao, Panagiotis Papageorgis, Hamid Mostafavi Abdolmaleky, Douglas V. Faller & Sam Thiagalingam
Pages: 1638-1643
Published online: 01 Oct 2007
AbstractforAberrant activation of γ-catenin promotes genomic instability and oncogenic effects during tumor progression | PDF (434 KB)
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Article
Activation of polyamine catabolism by N1, N11-diethylnorspermine alters the cellular localization of mTOR and downregulates mTOR protein level in glioblastoma cells
Rongcai Jiang, Woonyoung Choi, Limei Hu, Eugene W. Gerner, Stanley R. Hamilton & Wei Zhang
Pages: 1644-1648
Published online: 01 Oct 2007
AbstractforActivation of polyamine catabolism by N1, N11-diethylnorspermine alters the cellular localization of mTOR and downregulates mTOR protein level in glioblastoma cells | PDF (374.6 KB)
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Article
Multimodality optical imaging and 18F-FDG uptake in wild-type p53-containing and p53-null human colon tumor xenografts
Shulin Wang, Akiva Mintz, Kenjiro Mochizuki, Jay F. Dorsey, Joseph M. Ackermann, Abass Alavi & Wafik S. El-Deiry
Pages: 1649-1653
Published online: 01 Oct 2007
AbstractforMultimodality optical imaging and 18F-FDG uptake in wild-type p53-containing and p53-null human colon tumor xenografts | PDF (591.1 KB)
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Profiles and Legacies

Editorial
Success and failure on the ras pathway
Frank McCormick
Pages: 1654-1659
Published online: 01 Oct 2007
First Page PreviewforSuccess and failure on the ras pathway | PDF (174.4 KB)
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