Cancer Biology & Therapy, Volume 7, Issue 11 (2008)

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Cancer Biology & Therapy, Volume 7, Issue 11 (2008)

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Editor's Corner

Editorial
Cover Caption
Page: i
Published online: 01 Nov 2008
AbstractforCover Caption | PDF (10.4 MB)
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News

News
Biochemist Robert Tjian Elected as New Hughes President
Page: 1705
Published online: 01 Nov 2008
AbstractforBiochemist Robert Tjian Elected as New Hughes President | PDF (148.6 KB)
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Review

Review Article
Wnt signaling and senescence: A tug of war in early neoplasia?
Peter D. Adams & Greg H. Enders
Pages: 1706-1711
Published online: 01 Nov 2008
AbstractforWnt signaling and senescence: A tug of war in early neoplasia? | PDF (334.5 KB)
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Review Article
Androgens and epithelial ovarian cancer: What's the connection?
Beth Y. Karlan & Andrew John Li
Pages: 1712-1716
Published online: 01 Nov 2008
AbstractforAndrogens and epithelial ovarian cancer: What's the connection? | PDF (383.1 KB)
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Research Paper

Article
scFv-Mediated delivery of truncated BID suppresses HER2-positive osteosarcoma growth and metastasis
Le-Qun Shan, Xiu-Chun Qiu, Yan-Ming Xu, Zheng-Gang Ji, Tong-Tao Yang, Xiang Chen, Bao-An Ma, Yong Zhou, Qing-Yu Fan & An-Gang Yang
Pages: 1717-1722
Published online: 01 Nov 2008
AbstractforscFv-Mediated delivery of truncated BID suppresses HER2-positive osteosarcoma growth and metastasis | PDF (543.5 KB)
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Commentary

Can you tBID on it?
Şahru Yüksel & Nesrin Özören
Pages: 1723-1725
Published online: 01 Nov 2008
AbstractforCan you tBID on it? | PDF (415.6 KB)
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Research Paper

Article
Proteasome-dependent degradation of Chk1 kinase induced by the topoisomerase II inhibitor R16 contributes to its anticancer activity
Jian-Ming Feng, Hong Zhu, Xiao-Wei Zhang, Jian Ding & Ze-Hong Miao
Pages: 1726-1731
Published online: 01 Nov 2008
AbstractforProteasome-dependent degradation of Chk1 kinase induced by the topoisomerase II inhibitor R16 contributes to its anticancer activity | PDF (404.3 KB)
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Article
Tumorigenic transformation of human breast epithelial cells induced by mitochondrial DNA depletion
Mariola Kulawiec, Alfiya F. Safina, Mohamed M. Desouki, Ivan Still, Sei-Ichi Matsui, Andrei Bakin & Keshav K Singh
Pages: 1732-1743
Published online: 01 Nov 2008
AbstractforTumorigenic transformation of human breast epithelial cells induced by mitochondrial DNA depletion | PDF (2 MB)
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Article
In vitro and in vivo antitumor effect of a trivalent bispecific antibody targeting ErbB2 and CD16
Han Lu, Ming Shi, Mingli Wang, Zhigang Xie, Meiru Hu, Ming Yu, Beifen Shen, Yuanfang Ma & Ning Guo
Pages: 1744-1750
Published online: 01 Nov 2008
AbstractforIn vitro and in vivo antitumor effect of a trivalent bispecific antibody targeting ErbB2 and CD16 | PDF (870.5 KB)
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Commentary

Nature’s design – a blueprint for engineered therapeutic antibodies
Ulrich Rodeck & John C. Williams
Pages: 1751-1752
Published online: 01 Nov 2008
AbstractforNature’s design – a blueprint for engineered therapeutic antibodies | PDF (216.8 KB)
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Research Paper

Article
Establishment and characterization of a bona fide Barrett esophagus-associated adenocarcinoma cell line
Alvarez Hector, Jan-Bart M. Koorstra, Seung-Mo Hong, Jurjen J. Boonstra, Winand N.M. Dinjens, Arlene A. Foratiere, Tsung-Teh Wu, Elizabeth A. Montgomery, James R. Eshleman & Anirban Maitra
Pages: 1753-1755
Published online: 01 Nov 2008
AbstractforEstablishment and characterization of a bona fide Barrett esophagus-associated adenocarcinoma cell line | PDF (1.1 MB)
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Commentary

Cellular biometrics in the postgenomics era
Douglas B. Stairs, Shinya Ohashi & Hiroshi Nakagawa
Pages: 1756-1757
Published online: 01 Nov 2008
AbstractforCellular biometrics in the postgenomics era | PDF (131.5 KB)
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Research Paper

Article
c-Myb oncoprotein is an essential target of the dleu2 tumor suppressor microRNA cluster
Elaine Y. Chung, Michael Dews, Diana Cozma, Duonan Yu, Erik A. Wentzel, Tsung-Cheng Chang, Janell M. Schelter, Michele A. Cleary, Joshua T. Mendell & Andrei Thomas-Tikhonenko
Pages: 1758-1764
Published online: 01 Nov 2008
Abstractforc-Myb oncoprotein is an essential target of the dleu2 tumor suppressor microRNA cluster | PDF (910.5 KB)
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Article
Anti colon cancer components from Lebanese sage (Salvia libanotica) essential oil: Mechanistic basis
Wafica S. Itani, Sarah H. El-Banna, Saadia B. Hassan, Rolf L. Larsson, Ali Bazarbachi & Hala U. Gali-Muhtasib
Pages: 1765-1773
Published online: 01 Nov 2008
AbstractforAnti colon cancer components from Lebanese sage (Salvia libanotica) essential oil: Mechanistic basis | PDF (1.4 MB)
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Article
Comedo-Ductal carcinoma in situ: A paradoxical role for programmed cell death
Malathy P.V. Shekhar, Larry Tait, Robert J. Pauley, Gen Sheng Wu, Steven J. Santner, Pratima Nangia-Makker, Varun Shekhar, Hind Nassar, Daniel W. Visscher, Gloria H. Heppner & Fred R. Miller
Pages: 1774-1782
Published online: 01 Nov 2008
AbstractforComedo-Ductal carcinoma in situ: A paradoxical role for programmed cell death | PDF (1.1 MB)
  • 515 Views
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Article
Deficiency of Bloom syndrome helicase activity is radiomimetic
David P. Horowitz, Ozlem Topaloglu, Yonggang Zhang & Fred Bunz
Pages: 1783-1786
Published online: 01 Nov 2008
AbstractforDeficiency of Bloom syndrome helicase activity is radiomimetic | PDF (390.1 KB)
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Article
Concomitant activation of the JAK/STAT3 and ERK1/2 signaling is involved in leptin-mediated proliferation of renal cell carcinoma Caki-2 cells
Lei Li, Ye Gao, Lin-Lin Zhang & Da-lin He
Pages: 1787-1792
Published online: 01 Nov 2008
AbstractforConcomitant activation of the JAK/STAT3 and ERK1/2 signaling is involved in leptin-mediated proliferation of renal cell carcinoma Caki-2 cells | PDF (681.4 KB)
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Article
Copy number alterations in pancreatic cancer identify recurrent PAK4 amplification
Shuaili Chen, Theresa Auletta, Ostap Dovirak, Christina Hutter, Karen Kuntz, Samyra El-ftesi, Jude Kendall, Haiyong Han, Daniel D. Von Hoff, Raheela Ashfaq, Anirban Maitra, Christine A. Iacobuzio-Donahue, Ralph H. Hruban & Robert Lucito
Pages: 1793-1802
Published online: 01 Nov 2008
Abstractfor Copy number alterations in pancreatic cancer identify recurrent PAK4 amplification | PDF (2.1 MB)
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Commentary

Amplifying Pak kinases
Bettina Dummler & Jeffrey Field
Pages: 1803-1805
Published online: 01 Nov 2008
AbstractforAmplifying Pak kinases | PDF (246.9 KB)
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Research Paper

Article
Stromal SPARC expression and patient survival after chemoradiation for non-resectable pancreatic adenocarcinoma
Tine S. Mantoni, Roy R.E. Schendel, Franz Rödel, Gerald Niedobitek, Osama Al-Assar, Atsuhi Masamune & Thomas B. Brunner
Pages: 1806-1815
Published online: 01 Nov 2008
AbstractforStromal SPARC expression and patient survival after chemoradiation for non-resectable pancreatic adenocarcinoma | PDF (1,018.1 KB)
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Commentary

Tumor: Stroma interactions in pancreatic pancer: Will this sparc prove a raging fire?
Keith A Cengel & Christine Edmonds
Pages: 1816-1817
Published online: 01 Nov 2008
AbstractforTumor: Stroma interactions in pancreatic pancer: Will this sparc prove a raging fire? | PDF (133.1 KB)
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Research Paper

Article
Co-expression of EGFRvIII with ErbB-2 enhances tumorigenesis: EGFRvIII mediated constitutively activated and sustained signaling pathways, whereas EGF-induced a transient effect on EGFR-mediated signaling pathways
Hong Yu, Xiaoqi Gong, Xunyi Luo, Wei Han, Ge Hong, Baljit Singh & Careen K. Tang
Pages: 1818-1828
Published online: 01 Nov 2008
AbstractforCo-expression of EGFRvIII with ErbB-2 enhances tumorigenesis: EGFRvIII mediated constitutively activated and sustained signaling pathways, whereas EGF-induced a transient effect on EGFR-mediated signaling pathways | PDF (1.7 MB)
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Article
Effect of a novel inhibitory mAb antibody against β-subunit of F1F0 ATPase on HCC
Jingbo Wang, Ying Han, Jie Liang, Xin Cheng, Li Yan, Yingmei Wang, Jingmei Liu, Guanhong Luo, Xiong Cheng, Lina Zhao, Xinmin Zhou, Kaichun Wu & Daiming Fan
Pages: 1829-1835
Published online: 01 Nov 2008
AbstractforEffect of a novel inhibitory mAb antibody against β-subunit of F1F0 ATPase on HCC | PDF (712.8 KB)
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Commentary

Targeting cell surface F1F0 ATP synthase in cancer therapy
Yvonne M. Mowery & Salvatore V. Pizzo
Pages: 1836-1838
Published online: 01 Nov 2008
AbstractforTargeting cell surface F1F0 ATP synthase in cancer therapy | PDF (207.8 KB)
  • 473 Views
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Research Paper

Article
Tumor cell-specific blockade of CXCR4/SDF-1 interactions in prostate cancer cells by hTERT promoter induced CXCR4 knockdown: A possible metastasis preventing and minimizing approach
Yifei Xing, Mei Liu, Yuefeng Du, Feng Qu, Yangsheng Li, Qingwei Zhang, Yajun Xiao, Jun Zhao, Fuqing Zeng & Chuanguo Xiao
Pages: 1839-1848
Published online: 01 Nov 2008
AbstractforTumor cell-specific blockade of CXCR4/SDF-1 interactions in prostate cancer cells by hTERT promoter induced CXCR4 knockdown: A possible metastasis preventing and minimizing approach | PDF (1.2 MB)
  • 449 Views
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Commentary

New insights into the role of CXCR4 in prostate cancer metastasis
Candece L. Gladson & Danny R. Welch
Pages: 1849-1851
Published online: 01 Nov 2008
AbstractforNew insights into the role of CXCR4 in prostate cancer metastasis | PDF (246.1 KB)
  • 250 Views
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Research Paper

Article
An investigation of the effects of nanosize delivery system for antisense oligonucleotide on esophageal squamous cancer cells
Huixiang Li, Jin Wang, Tianyang Zhou, Yingge Zhang & Zhenzhong Zhang
Pages: 1852-1859
Published online: 01 Nov 2008
AbstractforAn investigation of the effects of nanosize delivery system for antisense oligonucleotide on esophageal squamous cancer cells | PDF (855.5 KB)
  • 265 Views
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Commentary

Nanosize delivery as an emerging platform for cancer therapy
Chun-Qi Li & Guang-Xian Zhang
Pages: 1860-1862
Published online: 01 Nov 2008
AbstractforNanosize delivery as an emerging platform for cancer therapy | PDF (191.8 KB)
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