Cancer Biology & Therapy, Volume 7, Issue 1 (2008)

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Cancer Biology & Therapy, Volume 7, Issue 1 (2008)

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Editor's Corner

Editorial
Cover Image
Page: i
Published online: 01 Jan 2008
AbstractforCover Image | PDF (1 MB)
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Review

Review Article
Biology of breast cancer bone metastasis
Mojtaba Akhtari, Junaid Mansuri, Kam A. Newman, Theresa M. Guise & Prem Seth
Pages: 3-9
Published online: 01 Jan 2008
AbstractforBiology of breast cancer bone metastasis | PDF (182.1 KB)
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Journal Club

HIF-1α and STAT3 client proteins interacting with the cancer chaperone Hsp90: Therapeutic considerations
Hanna Leah Kim, Marco Cassone, Laszlo Otvos Jr.Paraskevi Vogiatzi
Pages: 10-14
Published online: 01 Jan 2008
AbstractforHIF-1α and STAT3 client proteins interacting with the cancer chaperone Hsp90: Therapeutic considerations | PDF (393.8 KB)
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Clinical Study

Article
Circulating biomarkers of bevacizumab activity in patients with breast cancer
Neelima Denduluri, Sherry X. Yang, Arlene W. Berman, Diana Nguyen, David J. Liewehr, Seth M. Steinberg & Sandra M. Swain
Pages: 15-20
Published online: 01 Jan 2008
AbstractforCirculating biomarkers of bevacizumab activity in patients with breast cancer | PDF (236.5 KB)
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Commentary

Biomarkers in breast cancer
Heather McArthur & Maura Dickler
Pages: 21-22
Published online: 01 Jan 2008
AbstractforBiomarkers in breast cancer | PDF (65.5 KB)
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Research Paper

Article
Genetic polymorphisms in OGG1 and their association with angiomyolipoma, a benign kidney tumor in patients with tuberous sclerosis
Samy L. Habib, Elaine Danial, Subrata Nath, Jennifer Schneider, Christopher P. Jenkinson, Ravindranath Duggirala, Hanna E. Abboud & Farook Thameem
Pages: 23-27
Published online: 01 Jan 2008
AbstractforGenetic polymorphisms in OGG1 and their association with angiomyolipoma, a benign kidney tumor in patients with tuberous sclerosis | PDF (304.1 KB)
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Article
The role of histamine in human mammary carcinogenesis: H3 and H4 receptors as potential therapeutic targets for breast cancer treatment.
Vanina Medina, Máximo Croci, Ernesto Crescenti, Nora Mohamad, Francisca Sanchez-Jiménez, Noelia Massari, Mariel Nuñez, Graciela Cricco, Gabriela Martin, Rosa Bergoc & Elena S. Rivera
Pages: 28-35
Published online: 01 Jan 2008
AbstractforThe role of histamine in human mammary carcinogenesis: H3 and H4 receptors as potential therapeutic targets for breast cancer treatment. | PDF (425.5 KB)
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Commentary

Histamine in cancer: The dual faces of the coin
Fabio Cianchi, Maria Cristina Vinci & Emanuela Masini
Pages: 36-37
Published online: 01 Jan 2008
AbstractforHistamine in cancer: The dual faces of the coin | PDF (64.7 KB)
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Research Paper

Article
MDM2 displays differential activities dependent upon the activation status of NFκB
Misty D. Cheney, Pamela P. McKenzie, Erin L. Volk, Liying Fan & Linda C. Harris
Pages: 38-44
Published online: 01 Jan 2008
AbstractforMDM2 displays differential activities dependent upon the activation status of NFκB | PDF (765.5 KB)
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Article
Expression and significance of HERG protein in gastric cancer
Xiao-Dong Shao, Kai-Chun Wu, Xiao-Zhong Guo, Man-Jiang Xie, Jing Zhang & Dai-Ming Fan
Pages: 45-50
Published online: 01 Jan 2008
AbstractforExpression and significance of HERG protein in gastric cancer | PDF (477.6 KB)
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Article
Synergistic cytotoxicity of Bcl-xL inhibitor, gossypol and chemotherapeutic agents in non-Hodgkin’s lymphoma cells
Zhi-Ming Li, Wen-Qi Jiang, Zhen-Yu Zhu, Xiao-Feng Zhu, Jun-Min Zhou, Zong-Chao Liu, Da-Jun Yang & Zhong-Zhen Guan
Pages: 51-60
Published online: 01 Jan 2008
AbstractforSynergistic cytotoxicity of Bcl-xL inhibitor, gossypol and chemotherapeutic agents in non-Hodgkin’s lymphoma cells | PDF (800.3 KB)
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Commentary

Targeting Bcl-xL enhances the cytotoxicity of chemotherapeutics
Shulin Wang
Pages: 61-62
Published online: 01 Jan 2008
AbstractforTargeting Bcl-xL enhances the cytotoxicity of chemotherapeutics | PDF (134.4 KB)
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Research Paper

Article
The role of p53 in the trafficking of copper-64 to tumor cell nuclei
Martin Eiblmaier, Laura A. Meyer & Carolyn J. Anderson
Pages: 63-69
Published online: 01 Jan 2008
AbstractforThe role of p53 in the trafficking of copper-64 to tumor cell nuclei | PDF (224 KB)
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Article
Downregulation of IgG Fc binding protein (FcγBP) in prostate cancer
Mozammel H. Gazi, MeiLan He, John C. Cheville & Charles Y.F. Young
Pages: 70-75
Published online: 01 Jan 2008
AbstractforDownregulation of IgG Fc binding protein (FcγBP) in prostate cancer | PDF (360.8 KB)
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Article
Bismuth-213 radioimmunotherapy with C595 anti–MUC1 monoclonal antibody in an ovarian cancer ascites model
Emma Y. Song, Chang F Qu, Syed M.A. Rizvi, Chand Raja, Julia Beretov, Alfred Morgenstern, Christos Apostolidis, Frank Bruchertseifer, Alan Perkins & Barry J Allen
Pages: 76-80
Published online: 01 Jan 2008
AbstractforBismuth-213 radioimmunotherapy with C595 anti–MUC1 monoclonal antibody in an ovarian cancer ascites model | PDF (461.5 KB)
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Commentary

Targeting the human MUC1 oncoprotein: A tale of two proteins
Donald W. Kufe
Pages: 81-84
Published online: 01 Jan 2008
AbstractforTargeting the human MUC1 oncoprotein: A tale of two proteins | PDF (201.6 KB)
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Research Paper

Article
Modulation in the activity of lactate dehydrogenase and level of c-Myc and c-Fos by modified base queuine in cancer
Chandramani Pathak, Yogesh K. Jaiswal & Manjula Vinayak
Pages: 85-91
Published online: 01 Jan 2008
AbstractforModulation in the activity of lactate dehydrogenase and level of c-Myc and c-Fos by modified base queuine in cancer | PDF (338.1 KB)
  • 594 Views
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Article
The effectiveness of retinoic acid treatment in bladder cancer: Impact on recurrence, survival and TGFα and VEGF as end-point biomarkers.
Diaa A. Hameed & Tarek H. El-Metwally
Pages: 92-100
Published online: 01 Jan 2008
AbstractforThe effectiveness of retinoic acid treatment in bladder cancer: Impact on recurrence, survival and TGFα and VEGF as end-point biomarkers. | PDF (389.1 KB)
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Commentary

Prevention of bladder cancer recurrence by retinoic acid-ketoconazole: A promising strategy?
Yair Lotan & Rueben Lotan
Pages: 101-102
Published online: 01 Jan 2008
AbstractforPrevention of bladder cancer recurrence by retinoic acid-ketoconazole: A promising strategy? | PDF (68.3 KB)
  • 155 Views
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Research Paper

Article
Development of Ad-mda7/IL-24-resistant lung cancer cell lines
Abujiang Pataer, Sunil Chada, Jack A. Roth, Kelly K. Hunt & Stephen G. Swisher
Pages: 103-108
Published online: 01 Jan 2008
AbstractforDevelopment of Ad-mda7/IL-24-resistant lung cancer cell lines | PDF (679.5 KB)
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Commentary

Acquired and innate resistance to the cancer-specific apoptosis-inducing Cytokine, mda-7/IL-24: Not insurmountable therapeutic problems
Devanand Sarkar, Paul Dent, David T. Curiel & Paul B. Fisher
Pages: 109-112
Published online: 01 Jan 2008
AbstractforAcquired and innate resistance to the cancer-specific apoptosis-inducing Cytokine, mda-7/IL-24: Not insurmountable therapeutic problems | PDF (231.6 KB)
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Research Paper

Article
Ciprofloxacin-induced G2 arrest and apoptosis in TK6 lymphoblastoid cells is not dependent on DNA double-strand break formation
Daniel J. Smart, H. Dorota Halicka, Frank Traganos, Zbigniew Darzynkiewicz & Gary M. Williams
Pages: 113-119
Published online: 01 Jan 2008
AbstractforCiprofloxacin-induced G2 arrest and apoptosis in TK6 lymphoblastoid cells is not dependent on DNA double-strand break formation | PDF (607.8 KB)
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Article
hADA2a and hADA3 are required for acetylation, transcriptional activity and proliferative effects of beta-catenin
Min Yang, Marian L. Waterman & Rainer K. Brachmann
Pages: 120-128
Published online: 01 Jan 2008
AbstractforhADA2a and hADA3 are required for acetylation, transcriptional activity and proliferative effects of beta-catenin | PDF (827.2 KB)
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Commentary

hADA2a and hADA3: new players in ß-catenin signaling
Charles Lopez, Joshi Alumkal & Katy Van Hook
Pages: 129-130
Published online: 01 Jan 2008
AbstractforhADA2a and hADA3: new players in ß-catenin signaling | PDF (62.1 KB)
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Research Paper

Article
The effect of fatty acid-CoA ligase 4 on the growth of hepatic cancer cells
Chuangying Hu, Liang Chen, Yong Jiang, Yi Li & Shaofeng Wang
Pages: 131-134
Published online: 01 Jan 2008
AbstractforThe effect of fatty acid-CoA ligase 4 on the growth of hepatic cancer cells | PDF (125.5 KB)
  • 270 Views
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Article
Allele-specific expression in the germline of patients with familial pancreatic cancer: An unbiased approach to cancer gene discovery
Aik Choon Tan, Jian-Bing Fan, Collins Karikari, Marina Bibikova, Eliza Wickham Garcia, Lixin Zhou, David Barker, David Serre, Georg Feldmann, Ralph H. Hruban, Alison P. Klein, Michael Goggins, Fergus J. Couch, Thomas J. Hudson, Raimond L. Winslow, Anirban Maitra & Aravinda Chakravarti
Pages: 135-144
Published online: 01 Jan 2008
AbstractforAllele-specific expression in the germline of patients with familial pancreatic cancer: An unbiased approach to cancer gene discovery | PDF (717.5 KB) | Supplemental
  • 470 Views
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Article
Oral administration of attenuated S. typhimurium carrying shRNA-expressing vectors as a cancer therapeutic
Nan Yang, Xiangying Zhu, Lishan Chen, Shenghua Li & Daming Ren
Pages: 145-151
Published online: 01 Jan 2008
AbstractforOral administration of attenuated S. typhimurium carrying shRNA-expressing vectors as a cancer therapeutic | PDF (619.1 KB)
  • 702 Views
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Commentary

Salmonella typhimurium as a novel RNA interference vector for cancer gene therapy
Meenhard Herlyn & Devraj Basu
Pages: 152-153
Published online: 01 Jan 2008
AbstractforSalmonella typhimurium as a novel RNA interference vector for cancer gene therapy | PDF (73 KB)
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