Cancer Biology & Therapy, Volume 8, Issue 21 (2009)

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Cancer Biology & Therapy, Volume 8, Issue 21 (2009)

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Editor's Corner

Editorial
Cover caption
Page: 0
Published online: 01 Nov 2009
AbstractforCover caption | PDF (521.3 KB)
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News

News
Chad A. Ellis, PhD appointed Deputy Director for Research at Yale Cancer Center
Pages: 1975-1974
Published online: 01 Nov 2009
AbstractforChad A. Ellis, PhD appointed Deputy Director for Research at Yale Cancer Center | PDF (1.6 MB)
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News
Michele Carbone appointed as director of University of Hawaii's Cancer Research Center
Pages: 1975-1980
Published online: 01 Nov 2009
AbstractforMichele Carbone appointed as director of University of Hawaii's Cancer Research Center | PDF (1.6 MB)
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News
Federal stimulus package funds innovative cancer studies
Pages: 1975-1980
Published online: 01 Nov 2009
AbstractforFederal stimulus package funds innovative cancer studies | PDF (1.6 MB)
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News
Using RNAi-based technique, CSHL scientists find new tumor suppressor genes in lymphoma
Pages: 1975-1980
Published online: 01 Nov 2009
AbstractforUsing RNAi-based technique, CSHL scientists find new tumor suppressor genes in lymphoma | PDF (1.6 MB)
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News
NIH awards M.D. Anderson 84 research grants from stimulus funds
Pages: 1975-1980
Published online: 01 Nov 2009
AbstractforNIH awards M.D. Anderson 84 research grants from stimulus funds | PDF (1.6 MB)
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News
Inhibitor of heat shock protein is a potential anticancer drug, Penn study finds
Pages: 1975-1980
Published online: 01 Nov 2009
AbstractforInhibitor of heat shock protein is a potential anticancer drug, Penn study finds | PDF (1.6 MB)
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Meeting Report

Meeting Report
The biology of hormone refractory breast and prostate cancer: An NCI workshop report
Suresh Mohla, Vered Stearns, Neeraja Sathyamoorthy, Michael G Rosenfeld & Peter Nelson
Pages: 1975-1985
Published online: 01 Nov 2009
AbstractforThe biology of hormone refractory breast and prostate cancer: An NCI workshop report | PDF (1.6 MB)
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Review

Review Article
Emerging role of Notch signaling in epidermal differentiation and skin cancer
John Panelos & Daniela Massi
Pages: 1986-1993
Published online: 01 Nov 2009
AbstractforEmerging role of Notch signaling in epidermal differentiation and skin cancer | PDF (2.2 MB)
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Review Article
Modulating the tumor microenvironment to increase radiation responsiveness
Jayashree Karar & Amit Maity
Pages: 1994-2001
Published online: 01 Nov 2009
AbstractforModulating the tumor microenvironment to increase radiation responsiveness | PDF (1.9 MB)
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Journal Club

A genomic strategy for predicting androgen receptor activity in prostate tumors
Johann G. Jonsson, Tristan Sissung & William D. Figg
Pages: 2002-2003
Published online: 01 Nov 2009
AbstractforA genomic strategy for predicting androgen receptor activity in prostate tumors | PDF (1.3 MB)
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Clinical Study

Article
Immunohistochemical detection of poly(ADP-ribose) polymerase inhibition by ABT-888 in patients with refractory solid tumors and lymphomas
Sherry X. Yang, Shivaani Kummar, Seth M. Steinberg, Anthony J. Murgo, Martin Gutierrez, Larry Rubinstein, Dat Nguyen, Gurmeet Kaur, Alice P. Chen, Vincent L Giranda, Joseph E. Tomaszewski, James H. Doroshow & The National Cancer Institute Phase 0 Working Group
Pages: 2004-2009
Published online: 01 Nov 2009
AbstractforImmunohistochemical detection of poly(ADP-ribose) polymerase inhibition by ABT-888 in patients with refractory solid tumors and lymphomas | PDF (2.5 MB)
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Commentary

Target validation using Phase 0 clinical trials: Promises and pitfalls
Laura S. Angelo & Razelle Kurzrock
Pages: 2010-2012
Published online: 01 Nov 2009
Abstractfor Target validation using Phase 0 clinical trials: Promises and pitfalls | PDF (1.4 MB)
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Research Paper

Article
A resource for analysis of microRNA expression and function in pancreatic ductal adenocarcinoma cells
Oliver A. Kent, Michael E. Mullendore, Eric A. Wentzel, Pedro López-Romero, Aik Choon Tan, Alvarez Hector, Kristen West, Michael F. Ochs, Manuel Hidalgo, Dan E. Arking, Anirban Maitra & Joshua T. Mendell
Pages: 2013-2024
Published online: 01 Nov 2009
AbstractforA resource for analysis of microRNA expression and function in pancreatic ductal adenocarcinoma cells | PDF (1.6 MB) | Supplemental
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Article
Identification of HLA-A11-restricted CTL epitopes derived from HPV type 18 using DNA immunization
Hsin-Wei Chen, Chih-Hsiang Leng, Hsin-Yu Liu, Wen-Fang Cheng, Yu-Wen Chang, Pin-Yi Wu, Shu-Pei Lien, Tzu-Yi Huang, Sheng-Kuo Chiang, Min-Han Lin, Mi-Hua Tao, Pele Chong & Shih-Jen Liu
Pages: 2025-2032
Published online: 01 Nov 2009
AbstractforIdentification of HLA-A11-restricted CTL epitopes derived from HPV type 18 using DNA immunization | PDF (2 MB)
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Article
Somatostatin receptor scintigraphy screening in advanced hepatocarcinoma: A multicenter French study
Eric Nguyen-Khac, Isabelle Ollivier, Thomas Aparicio, Véronique Moullart, Alexis Hugentobler, Rachida Lebtahi, Céline Lobry, Christiane Susini, Christian Duhamel, Séverine Hommel, Jean François Cadranel, Jean-paul Joly, Jean Claude Barbare, Blaise Tramier & Jean Louis Dupas
Pages: 2033-2039
Published online: 01 Nov 2009
Abstractfor Somatostatin receptor scintigraphy screening in advanced hepatocarcinoma: A multicenter French study | PDF (2 MB)
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Commentary

Somatostatin analogs and hepatocellular carcinoma; not dead yet?
Laura Raftery & Bert H. O’Neil
Pages: 2040-2041
Published online: 01 Nov 2009
AbstractforSomatostatin analogs and hepatocellular carcinoma; not dead yet? | PDF (1.3 MB)
  • 57 Views
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Research Paper

Article
Amplification of chromosomal segment 4q12 in non-small cell lung cancer
Alex H. Ramos, Amit Dutt, Craig Mermel, Sven Perner, Jeonghee Cho, Christopher J. LaFargue, Laura A. Johnson, Ann-Cathrin Stiedl, Kumiko E. Tanaka, Adam Bass, Jordi Barretina, Barbara A. Weir, Rameen Beroukhim, Roman K. Thomas, John D. Minna, Lucian R. Chirieac, Neal I. Lindeman, Thomas J. Giordano, David G. Beer, Patrick Wagner, Ignacio Wistuba, Mark A. Rubin & Matthew Meyerson
Pages: 2042-2050
Published online: 01 Nov 2009
AbstractforAmplification of chromosomal segment 4q12 in non-small cell lung cancer | PDF (2.2 MB)
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Commentary

Advances in personalised therapeutics in non-small cell lung cancer: 4q12 amplification, PDGFRA oncogene addiction and sunitinib sensitivity
Rebecca A. Burrell & Charles Swanton
Pages: 2051-2053
Published online: 01 Nov 2009
AbstractforAdvances in personalised therapeutics in non-small cell lung cancer: 4q12 amplification, PDGFRA oncogene addiction and sunitinib sensitivity | PDF (1.6 MB)
  • 277 Views
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Research Paper

Article
Triptolide: An inhibitor of a disintegrin and metalloproteinase 10 (ADAM10) in cancer cells
Ramani Soundararajan, Ria Sayat, George S. Robertson & Paola A. Marignani
Pages: 2054-2062
Published online: 01 Nov 2009
AbstractforTriptolide: An inhibitor of a disintegrin and metalloproteinase 10 (ADAM10) in cancer cells | PDF (2 MB)
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Commentary

Ancient drugs, modern targets
Fred Bunz
Pages: 2063-2064
Published online: 01 Nov 2009
AbstractforAncient drugs, modern targets | PDF (1.4 MB)
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Research Paper

Article
Uniquely modified RNA oligonucleotides targeting STAT3 suppress melanoma growth both in vitro and in vivo
Lifang Yang, Ma Xiaoqian, Xiao Lanbo, Tang Min, Weng Xinxiang, Sun Lunquan & Cao Ya
Pages: 2065-2072
Published online: 01 Nov 2009
Abstractfor Uniquely modified RNA oligonucleotides targeting STAT3 suppress melanoma growth both in vitro and in vivo | PDF (1.3 MB)
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Article
High level of AKT activity is associated with resistance to MEK inhibitor AZD6244 (ARRY-142886)
Jieru Meng, Henry Peng, Bingbing Dai, Wei Guo, Li Wang, Lin Ji, John D. Minna, Christine M. Chresta, Paul D. Smith, Bingliang Fang & Jack A. Roth
Pages: 2073-2080
Published online: 01 Nov 2009
AbstractforHigh level of AKT activity is associated with resistance to MEK inhibitor AZD6244 (ARRY-142886) | PDF (2.4 MB)
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Commentary

Lung cancer profiling: genetic and molecular predictors of MEK-dependence.
Aphrothiti J. Hanrahan & David B. Solit
Pages: 2081-2083
Published online: 01 Nov 2009
AbstractforLung cancer profiling: genetic and molecular predictors of MEK-dependence. | PDF (1.5 MB)
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Research Paper

Article
Inhibition of MCL-1 enhances Lapatinib toxicity and overcomes lapatinib resistance via BAK-dependent autophagy
Aditi Pandya Martin, Clint Mitchell, Mohammed Rahmani, Kenneth P. Nephew, Steven Grant & Paul Dent
Pages: 2084-2096
Published online: 01 Nov 2009
AbstractforInhibition of MCL-1 enhances Lapatinib toxicity and overcomes lapatinib resistance via BAK-dependent autophagy | PDF (2.9 MB)
  • 209 Views
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Commentary

Autophagy can contribute to cell death when combining targeted therapy
Ravi Amaravadi
Pages: 2097-2100
Published online: 01 Nov 2009
AbstractforAutophagy can contribute to cell death when combining targeted therapy | PDF (1.5 MB)
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