Cancer Biology & Therapy, Volume 8, Issue 5 (2009)

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Cancer Biology & Therapy, Volume 8, Issue 5 (2009)

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Editor's Corner

Editorial
Cover caption
Page: i
Published online: 01 Mar 2009
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News

News
Researchers discover metabolite linked to aggressive prostate cancer: Finding could lead to test to help guide treatment decisions
Pages: 397-401
Published online: 01 Mar 2009
AbstractforResearchers discover metabolite linked to aggressive prostate cancer: Finding could lead to test to help guide treatment decisions | PDF (185.5 KB)
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News
UNC study: New genomic test may guide breast cancer treatment choices
Pages: 397-401
Published online: 01 Mar 2009
AbstractforUNC study: New genomic test may guide breast cancer treatment choices | PDF (185.5 KB)
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News
Mechanism identified that increases effectiveness of therapy against leukemia drug combination is five times more effective than individual drugs alone
Pages: 397-401
Published online: 01 Mar 2009
AbstractforMechanism identified that increases effectiveness of therapy against leukemia drug combination is five times more effective than individual drugs alone | PDF (185.5 KB)
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News
Targeted nanospheres find, penetrate, then fuel burning of melanoma peptide-guided hollow gold spheres gather inside tumors, where light heats them to kill
Pages: 397-401
Published online: 01 Mar 2009
AbstractforTargeted nanospheres find, penetrate, then fuel burning of melanoma peptide-guided hollow gold spheres gather inside tumors, where light heats them to kill | PDF (185.5 KB)
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News
New tool to predict how a chemotherapy drug will work on individual tumor
Pages: 397-401
Published online: 01 Mar 2009
AbstractforNew tool to predict how a chemotherapy drug will work on individual tumor | PDF (185.5 KB)
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News
Non-Profit Gives $800,000 for Melanoma Research in 2009
Pages: 397-401
Published online: 01 Mar 2009
AbstractforNon-Profit Gives $800,000 for Melanoma Research in 2009 | PDF (185.5 KB)
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Review

Review Article
Historical perspective and recent insights into our understanding of the molecular and biochemical basis of the antitumor properties of mda-7/IL-24
Luni Emdad, Irina V. Lebedeva, Zhao-zhong Su, Pankaj Gupta, Moira Sauane, Rupesh Dash, Steven Grant, Paul Dent, David T. Curiel, Devanand Sarkar & Paul B. Fisher
Pages: 402-411
Published online: 01 Mar 2009
AbstractforHistorical perspective and recent insights into our understanding of the molecular and biochemical basis of the antitumor properties of mda-7/IL-24 | PDF (498.5 KB)
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Review Article
The role of SMARCB1/INI1 in the development of rhabdoid tumors
Charles Roberts & Jaclyn Biegel
Pages: 412-416
Published online: 01 Mar 2009
AbstractforThe role of SMARCB1/INI1 in the development of rhabdoid tumors | PDF (210.8 KB)
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Clinical Case Report

Case Report
Case report of extrarenal rhabdoid tumor of pelvic retroperitoneum: Molecular profile of angiogenesis and its implication in new treatment strategy
Guioxiang Cai, Xiaoli Zhu, Ye Xu, Xiang Du, Zhen Zhang, Yingjian Zhang, Tongzhen Chen, Xiaoyan Zhou, Zuqing Guan & Sanjun Cai
Pages: 417-421
Published online: 01 Mar 2009
AbstractforCase report of extrarenal rhabdoid tumor of pelvic retroperitoneum: Molecular profile of angiogenesis and its implication in new treatment strategy | PDF (535.9 KB)
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Research Paper

Article
Ectopic expression of Histone H2AX mutants reveal a role for its post-translational modifications
Jonathan Rios-Doria, Aneliya Velkova, Virna Dapic, José M. Galán-Caridad, Vesna Dapic, Marcelo A. Carvalho, Johana Melendez & Alvaro N. A. Monteiro
Pages: 422-434
Published online: 01 Mar 2009
AbstractforEctopic expression of Histone H2AX mutants reveal a role for its post-translational modifications | PDF (4.4 MB)
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Article
Systemic administration of radiation-potentiated anti-angiogenic gene therapy against primary and metastatic cancer based on transcriptionally controlled HSV-TK
Israel Hodish, Reshef Tal, Aviv Shaish, Nira Varda-Bloom, Shoshana Greenberger, Ariela Rauchwerger, Eyal Breitbart, Livnat Bangio, Dikla Ben-Shushan, Raphael Pfeffer, Bela Feder, Ana Waitsman, Iris Barshack, Iris Goldberg, Shaly Mazaki-Tovi, Michael Peled & Dror Harats
Pages: 435-443
Published online: 01 Mar 2009
AbstractforSystemic administration of radiation-potentiated anti-angiogenic gene therapy against primary and metastatic cancer based on transcriptionally controlled HSV-TK | PDF (1.8 MB)
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Article
Inactivation of RASSF1A, RARβ2 and DAP-kinase by promoter methylation correlates with lymph node metastasis in nasopharyngeal carcinoma
Ali Fendri, Asma Masmoudi, Abdelmajid Khabir, Tahia Sellami-Boudawara, Jamel Daoud, Mounir Frikha, Abdelmonem Ghorbel, Ali Gargouri & Raja Mokdad-Gargouri
Pages: 444-451
Published online: 01 Mar 2009
AbstractforInactivation of RASSF1A, RARβ2 and DAP-kinase by promoter methylation correlates with lymph node metastasis in nasopharyngeal carcinoma | PDF (1.3 MB)
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Article
Diversity of DNA damage response of astrocytes and glioblastoma cell lines with various p53 status to treatment with etoposide and temozolomide
Yuichi Sato, Akira Kurose, Akira Ogawa, Kuniaki Ogasawara, Frank Traganos, Zbigniew Darzynkiewicz & Takashi Sawai
Pages: 452-457
Published online: 01 Mar 2009
AbstractforDiversity of DNA damage response of astrocytes and glioblastoma cell lines with various p53 status to treatment with etoposide and temozolomide | PDF (561.3 KB)
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Article
Discovery of a novel quinoxalinhydrazide with a broad-spectrum anticancer activity
Carmen Plasencia, Fedora Grande, Takashi Oshima, Xuefei Cao, Roppei Yamada, Tino Sanchez, Francesca Aiello, Antonio Garofalo & Nouri Neamati
Pages: 458-465
Published online: 01 Mar 2009
AbstractforDiscovery of a novel quinoxalinhydrazide with a broad-spectrum anticancer activity | PDF (2.5 MB)
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Article
Combined endostatin and TRAIL gene transfer suppresses human hepatocellular carcinoma growth and angiogenesis in nude mice
Yan Zhang, Zhong-Hua Qu, Min Cui, Chun Guo, Xiu-Mei Zhang, Chun-Hong Ma & Wen-Sheng Sun
Pages: 466-473
Published online: 01 Mar 2009
Abstractfor Combined endostatin and TRAIL gene transfer suppresses human hepatocellular carcinoma growth and angiogenesis in nude mice | PDF (5.8 MB)
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Commentary

A one, two punch for liver cancer: Anti-angiogenesis with a death receptor agonist
John P. Plastaras & Kevin R. Kozak
Pages: 474-475
Published online: 01 Mar 2009
AbstractforA one, two punch for liver cancer: Anti-angiogenesis with a death receptor agonist | PDF (103.2 KB)
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