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Volume 5, Issue 2

Biostatistics & Epidemiology

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Biostatistics & Epidemiology, Volume 5, Issue 2 (2021)

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Biostatistics & Epidemiology, Volume 5, Issue 2 (2021)

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Statistical Methods in Precision Medicine: Diagnostic, Prognostic, Predictive and Therapeutic

Editorial

Special issue introduction: Statistical Methods in Precision Medicine: Diagnostic, Prognostic, Predictive and Therapeutic

Gene Pennello & Xiting Yang

Pages: 93-99

Published online: 19 Oct 2021

First Page PreviewforSpecial issue introduction: Statistical Methods in Precision Medicine: Diagnostic, Prognostic, Predictive and Therapeutic | Full Text | References | PDF (521.2 KB) | EPUB

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Articles

Article

Developments and debates on latent variable modeling in diagnostic studies when there is no gold standard

Zheyu Wang

Pages: 100-117

Published online: 15 Oct 2019

AbstractforDevelopments and debates on latent variable modeling in diagnostic studies when there is no gold standard | Full Text | References | PDF (1.3 MB) | EPUB

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A note on modeling placement values in the analysis of receiver operating characteristic curves

Zhen Chen & Soutik Ghosal

Pages: 118-133

Published online: 22 Mar 2020

AbstractforA note on modeling placement values in the analysis of receiver operating characteristic curves | Full Text | References | PDF (2.1 MB) | EPUB

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Research Article

Article

Number needed to test: quantifying risk stratification provided by diagnostic tests and risk predictions

Hormuzd A. Katki, Rajib Dey & Paramita Saha-Chaudhuri

Pages: 134-148

Published online: 07 Aug 2020

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Article

Classification accuracy goals for diagnostic tests based on risk stratification

Gene Pennello

Pages: 149-168

Published online: 17 Mar 2021

415 Views
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Article

Comparative study of statistical methods for clustered ROC data: nonparametric methods and multiple outputation methods

Zhuang Miao, Liansheng Larry Tang & Ao Yuan

Pages: 169-188

Published online: 17 Mar 2021

AbstractforComparative study of statistical methods for clustered ROC data: nonparametric methods and multiple outputation methods | Full Text | References | PDF (1.7 MB) | EPUB

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Article

Estimating the AUC with a graphical lasso method for high-dimensional biomarkers with LOD

Jirui Wang, Yunpeng Zhao & Liansheng Larry Tang

Pages: 189-206

Published online: 17 Mar 2021

AbstractforEstimating the AUC with a graphical lasso method for high-dimensional biomarkers with LOD | Full Text | References | PDF (1.4 MB) | EPUB

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Article

A bivariate Bayesian framework for simultaneous evaluation of two candidate companion diagnostic assays in a new drug clinical trial

Richard M. Simon & Songbai Wang

Pages: 207-217

Published online: 25 Apr 2021

AbstractforA bivariate Bayesian framework for simultaneous evaluation of two candidate companion diagnostic assays in a new drug clinical trial | Full Text | References | PDF (1.2 MB) | EPUB

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Article

The role of statistics in the design and analysis of companion diagnostic (CDx) studies

Gregory Campbell

Pages: 218-231

Published online: 10 May 2021

AbstractforThe role of statistics in the design and analysis of companion diagnostic (CDx) studies | Full Text | References | PDF (1.1 MB) | EPUB

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Article

Concordance measures and time-dependent ROC methods

Norberto Pantoja-Galicia, Olivia I. Okereke, Deborah Blacker & Rebecca A. Betensky

Pages: 232-249

Published online: 25 May 2021

AbstractforConcordance measures and time-dependent ROC methods | Full Text | References | PDF (1.3 MB) | EPUB

397 Views
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Article

Dynamic prediction using joint models of longitudinal and recurrent event data: a Bayesian perspective

Xuehan Ren, Jue Wang & Sheng Luo

Pages: 250-266

Published online: 22 Nov 2019

AbstractforDynamic prediction using joint models of longitudinal and recurrent event data: a Bayesian perspective | Full Text | References | PDF (1.8 MB) | EPUB

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Research Article

Article

A statistical review: why average weighted accuracy, not accuracy or AUC?

Yunyun Jiang, Qing Pan, Ying Liu & Scott Evans

Pages: 267-286

Published online: 27 Sep 2021

AbstractforA statistical review: why average weighted accuracy, not accuracy or AUC? | Full Text | References | PDF (1.7 MB) | EPUB

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Biostatistics & Epidemiology (Vol.5, Iss.2, 2021)

Statistical Methods in Precision Medicine: Diagnostic, Prognostic, Predictive and Therapeutic

Statistical Methods in Precision Medicine: Diagnostic, Prognostic, Predictive and Therapeutic

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