Molecular and Cellular Biology, Volume 21, Issue 9 (2001)

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Molecular and Cellular Biology, Volume 21, Issue 9 (2001)

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Transcriptional Regulation

Article
Sequences Flanking Hypersensitive Sites of the β-Globin Locus Control Region Are Required for Synergistic Enhancement
Joseph M. Molete, Hanna Petrykowska, Eric E. Bouhassira, Yong-Qing Feng, Webb Miller & Ross C. Hardison
Pages: 2969-2980
Published online: 28 Mar 2023
AbstractforSequences Flanking Hypersensitive Sites of the β-Globin Locus Control Region Are Required for Synergistic Enhancement | Full Text | References | PDF (713.5 KB)
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Article
Identification of Liver X Receptor-Retinoid X Receptor as an Activator of the Sterol Regulatory Element-Binding Protein 1c Gene Promoter
Tomohiro Yoshikawa, Hitoshi Shimano, Michiyo Amemiya-Kudo, Naoya Yahagi, Alyssa H. Hasty, Takashi Matsuzaka, Hiroaki Okazaki, Yoshiaki Tamura, Yoko Iizuka, Ken Ohashi, Jun-Ichi Osuga, Kenji Harada, Takanari Gotoda, Satoshi Kimura, Shun Ishibashi & Nobuhiro Yamada
Pages: 2991-3000
Published online: 28 Mar 2023
AbstractforIdentification of Liver X Receptor-Retinoid X Receptor as an Activator of the Sterol Regulatory Element-Binding Protein 1c Gene Promoter | Full Text | References | PDF (275.3 KB)
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Article
Two Distinct Domains within CIITA Mediate Self-Association: Involvement of the GTP-Binding and Leucine-Rich Repeat Domains
Michael W. Linhoff, Jonathan A. Harton, Drew E. Cressman, Brian K. Martin & Jenny Pan-Yun Ting
Pages: 3001-3011
Published online: 28 Mar 2023
AbstractforTwo Distinct Domains within CIITA Mediate Self-Association: Involvement of the GTP-Binding and Leucine-Rich Repeat Domains | Full Text | References | PDF (527.1 KB)
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Article
Negative Regulation of CD4 Gene Expression by a HES-1–c-Myb Complex
Robert D. Allen III, Han K. Kim, Sophia D. Sarafova & Gerald Siu
Pages: 3071-3082
Published online: 28 Mar 2023
AbstractforNegative Regulation of CD4 Gene Expression by a HES-1–c-Myb Complex | Full Text | References | PDF (340.7 KB)
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Article
Role of NF-Y in In Vivo Regulation of the γ-Globin Gene
Zhijun Duan, George Stamatoyannopoulos & Qiliang Li
Pages: 3083-3095
Published online: 28 Mar 2023
AbstractforRole of NF-Y in In Vivo Regulation of the γ-Globin Gene | Full Text | References | PDF (714 KB)
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Article
High-Mobility-Group Proteins NHP6A and NHP6B Participate in Activation of the RNA Polymerase IIISNR6 Gene
Sébastien Lopez, Magda Livingstone-Zatchej, Sabine Jourdain, Fritz Thoma, André Sentenac & Marie-Claude Marsolier
Pages: 3096-3104
Published online: 28 Mar 2023
AbstractforHigh-Mobility-Group Proteins NHP6A and NHP6B Participate in Activation of the RNA Polymerase IIISNR6 Gene | Full Text | References | PDF (357.9 KB)
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Article
Unanticipated Repression Function Linked to Erythroid Krüppel-Like Factor
Xiaoyong Chen & James J. Bieker
Pages: 3118-3125
Published online: 28 Mar 2023
AbstractforUnanticipated Repression Function Linked to Erythroid Krüppel-Like Factor | Full Text | References | PDF (188.7 KB)
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Article
RNA Polymerase III Transcription Complexes on Chromosomal 5S rRNA Genes In Vivo: TFIIIB Occupancy and Promoter Opening
G. Costanzo, S. Camier, P. Carlucci, L. Burderi & R. Negri
Pages: 3166-3178
Published online: 28 Mar 2023
AbstractforRNA Polymerase III Transcription Complexes on Chromosomal 5S rRNA Genes In Vivo: TFIIIB Occupancy and Promoter Opening | Full Text | References | PDF (1,010.7 KB)
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Article
Identification of TFII-I as the Endoplasmic Reticulum Stress Response Element Binding Factor ERSF: Its Autoregulation by Stress and Interaction with ATF6
Ronald Parker, Trevor Phan, Peter Baumeister, Binayak Roy, Venugopalan Cheriyath, Ananda L. Roy & Amy S. Lee
Pages: 3220-3233
Published online: 28 Mar 2023
AbstractforIdentification of TFII-I as the Endoplasmic Reticulum Stress Response Element Binding Factor ERSF: Its Autoregulation by Stress and Interaction with ATF6 | Full Text | References | PDF (988.9 KB)
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Article
Hepatic Nuclear Factor 1-α Directs Nucleosomal Hyperacetylation to Its Tissue-Specific Transcriptional Targets
Marcelina Párrizas, Miguel A. Maestro, Sylvia F. Boj, Amaya Paniagua, Roser Casamitjana, Ramon Gomis, Francisca Rivera & Jorge Ferrer
Pages: 3234-3243
Published online: 28 Mar 2023
AbstractforHepatic Nuclear Factor 1-α Directs Nucleosomal Hyperacetylation to Its Tissue-Specific Transcriptional Targets | Full Text | References | PDF (1.2 MB)
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Article
Expression Level-Dependent Contribution of Glucocorticoid Receptor Domains for Functional Interaction with STAT5
Wolfgang Doppler, Michaela Windegger, Claudia Soratroi, Jürgen Tomasi, Judith Lechner, Sandro Rusconi, Andrew C. B. Cato, Tova Almlöf, Johan Liden, Sam Okret, Jan-Åke Gustafsson, Hélène Richard-Foy, D. Barry Starr, Helmut Klocker, Dean Edwards & Sibylle Geymayer
Pages: 3266-3279
Published online: 28 Mar 2023
AbstractforExpression Level-Dependent Contribution of Glucocorticoid Receptor Domains for Functional Interaction with STAT5 | Full Text | References | PDF (537.7 KB)
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Cell Growth and Development

Article
Phosphorylation of Nuclear Phospholipase C β1 by Extracellular Signal-Regulated Kinase Mediates the Mitogenic Action of Insulin-Like Growth Factor I
Aimin Xu, Pann-Ghill Suh, Nelly Marmy-Conus, Richard B. Pearson, Oh Yong Seok, Lucio Cocco & R. Stewart Gilmour
Pages: 2981-2990
Published online: 28 Mar 2023
AbstractforPhosphorylation of Nuclear Phospholipase C β1 by Extracellular Signal-Regulated Kinase Mediates the Mitogenic Action of Insulin-Like Growth Factor I | Full Text | References | PDF (344.3 KB)
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Article
AP-1 Repressor Protein JDP-2: Inhibition of UV-Mediated Apoptosis through p53 Down-Regulation
Fabrice Piu, Ami Aronheim, Sigal Katz & Michael Karin
Pages: 3012-3024
Published online: 28 Mar 2023
AbstractforAP-1 Repressor Protein JDP-2: Inhibition of UV-Mediated Apoptosis through p53 Down-Regulation | Full Text | References | PDF (606.4 KB)
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Article
Caspase Cleavage Enhances the Apoptosis-Inducing Effects of BAD
Fabrizio Condorelli, Paolo Salomoni, Sophie Cotteret, Vincenzo Cesi, Srinivasa M. Srinivasula, Emad S. Alnemri & Bruno Calabretta
Pages: 3025-3036
Published online: 28 Mar 2023
AbstractforCaspase Cleavage Enhances the Apoptosis-Inducing Effects of BAD | Full Text | References | PDF (418 KB)
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Article
Scaffolding Protein Gab2 Mediates Differentiation Signaling Downstream of Fms Receptor Tyrosine Kinase
Yan Liu, Brendan Jenkins, Jung Lim Shin & Larry R. Rohrschneider
Pages: 3047-3056
Published online: 28 Mar 2023
AbstractforScaffolding Protein Gab2 Mediates Differentiation Signaling Downstream of Fms Receptor Tyrosine Kinase | Full Text | References | PDF (311.8 KB)
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Article
Inhibition of Cellular Proliferation through IκB Kinase-Independent and Peroxisome Proliferator-Activated Receptor γ-Dependent Repression of Cyclin D1
Chenguang Wang, Maofu Fu, Mark D'Amico, Chris Albanese, Jian-Nian Zhou, Michael Brownlee, Michael P. Lisanti, V. Krishna K. Chatterjee, Mitchell A. Lazar & Richard G. Pestell
Pages: 3057-3070
Published online: 28 Mar 2023
AbstractforInhibition of Cellular Proliferation through IκB Kinase-Independent and Peroxisome Proliferator-Activated Receptor γ-Dependent Repression of Cyclin D1 | Full Text | References | PDF (457.3 KB)
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Article
Vav-Rac1-Mediated Activation of the c-Jun N-Terminal Kinase/c-Jun/AP-1 Pathway Plays a Major Role in Stimulation of the Distal NFAT Site in the Interleukin-2 Gene Promoter
Osamu Kaminuma, Marcel Deckert, Chris Elly, Yun-Cai Liu & Amnon Altman
Pages: 3126-3136
Published online: 28 Mar 2023
AbstractforVav-Rac1-Mediated Activation of the c-Jun N-Terminal Kinase/c-Jun/AP-1 Pathway Plays a Major Role in Stimulation of the Distal NFAT Site in the Interleukin-2 Gene Promoter | Full Text | References | PDF (483.2 KB)
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Article
Cyclic AMP-Dependent Protein Kinase Controls Virulence of the Fungal Pathogen Cryptococcus neoformans
Cletus A. D'Souza, J. Andrew Alspaugh, Changli Yue, Toshiaki Harashima, Gary M. Cox, John R. Perfect & Joseph Heitman
Pages: 3179-3191
Published online: 28 Mar 2023
AbstractforCyclic AMP-Dependent Protein Kinase Controls Virulence of the Fungal Pathogen Cryptococcus neoformans | Full Text | References | PDF (1.7 MB)
  • 79 Views
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Article
Induction of β3-Integrin Gene Expression by Sustained Activation of the Ras-Regulated Raf–MEK–Extracellular Signal-Regulated Kinase Signaling Pathway
Douglas Woods, Holly Cherwinski, Eleni Venetsanakos, Arun Bhat, Stephan Gysin, Martine Humbert, Paul F. Bray, Vicki L. Saylor & Martin McMahon
Pages: 3192-3205
Published online: 28 Mar 2023
AbstractforInduction of β3-Integrin Gene Expression by Sustained Activation of the Ras-Regulated Raf–MEK–Extracellular Signal-Regulated Kinase Signaling Pathway | Full Text | References | PDF (1.5 MB)
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Article
Control of Spermatogenesis in Mice by the Cyclin D-Dependent Kinase Inhibitors p18Ink4c and p19Ink4d
Frederique Zindy, Willem den Besten, Bo Chen, Jerold E. Rehg, Esther Latres, Mariano Barbacid, Jeffrey W. Pollard, Charles J. Sherr, Paula E. Cohen & Martine F. Roussel
Pages: 3244-3255
Published online: 28 Mar 2023
AbstractforControl of Spermatogenesis in Mice by the Cyclin D-Dependent Kinase Inhibitors p18Ink4c and p19Ink4d | Full Text | References | PDF (3.6 MB)
  • 39 Views
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Article
Accumulation of Cyclin E Is Not a Prerequisite for Passage through the Restriction Point
Susanna V. Ekholm, Peter Zickert, Steven I. Reed & Anders Zetterberg
Pages: 3256-3265
Published online: 28 Mar 2023
AbstractforAccumulation of Cyclin E Is Not a Prerequisite for Passage through the Restriction Point | Full Text | References | PDF (368 KB)
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Gene Expression

Article
A Novel Yeast U2 snRNP Protein, Snu17p, Is Required for the First Catalytic Step of Splicing and for Progression of Spliceosome Assembly
Alexander Gottschalk, Cornelia Bartels, Gitte Neubauer, Reinhard Lührmann & Patrizia Fabrizio
Pages: 3037-3046
Published online: 28 Mar 2023
AbstractforA Novel Yeast U2 snRNP Protein, Snu17p, Is Required for the First Catalytic Step of Splicing and for Progression of Spliceosome Assembly | Full Text | References | PDF (481.1 KB)
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Cell and Organelle Structure and Assembly

Article
Skp1p and the F-Box Protein Rcy1p Form a Non-SCF Complex Involved in Recycling of the SNARE Snc1p in Yeast
Jean-Marc Galan, Andreas Wiederkehr, Jae Hong Seol, Rosine Haguenauer-Tsapis, Raymond J. Deshaies, Howard Riezman & Matthias Peter
Pages: 3105-3117
Published online: 28 Mar 2023
AbstractforSkp1p and the F-Box Protein Rcy1p Form a Non-SCF Complex Involved in Recycling of the SNARE Snc1p in Yeast | Full Text | References | PDF (511.8 KB)
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Mammalian Genetic Models With Minimal Or Complex Phenotypes

Article
Gadd45γ Is Dispensable for Normal Mouse Development and T-Cell Proliferation
Angelika Hoffmeyer, Roland Piekorz, Richard Moriggl & James N. Ihle
Pages: 3137-3143
Published online: 28 Mar 2023
AbstractforGadd45γ Is Dispensable for Normal Mouse Development and T-Cell Proliferation | Full Text | References | PDF (326.4 KB)
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Article
Generation and Analysis of Mice Lacking the Chemokine Fractalkine
Donald N. Cook, Shu-Cheng Chen, Lee M. Sullivan, Denise J. Manfra, Maria T. Wiekowski, Dina M. Prosser, Galya Vassileva & Sergio A. Lira
Pages: 3159-3165
Published online: 28 Mar 2023
AbstractforGeneration and Analysis of Mice Lacking the Chemokine Fractalkine | Full Text | References | PDF (686.5 KB)
  • 47 Views
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Article
Immune System Dysfunction and Autoimmune Disease in Mice Lacking Emk (Par-1) Protein Kinase
Jonathan B. Hurov, Thaddeus S. Stappenbeck, Christian M. Zmasek, Lynn S. White, Sheila H. Ranganath, John H. Russell, Andrew C. Chan, Kenneth M. Murphy & Helen Piwnica-Worms
Pages: 3206-3219
Published online: 28 Mar 2023
AbstractforImmune System Dysfunction and Autoimmune Disease in Mice Lacking Emk (Par-1) Protein Kinase | Full Text | References | PDF (3.6 MB)
  • 47 Views
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Dna Dynamics and Chromosome Structure

Article
Saccharomyces cerevisiae CTF18 and CTF4 Are Required for Sister Chromatid Cohesion
Joseph S. Hanna, Evgueny S. Kroll, Victoria Lundblad & Forrest A. Spencer
Pages: 3144-3158
Published online: 28 Mar 2023
AbstractforSaccharomyces cerevisiae CTF18 and CTF4 Are Required for Sister Chromatid Cohesion | Full Text | References | PDF (637.6 KB)
  • 61 Views
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