Molecular and Cellular Biology, Volume 22, Issue 10 (2002)

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Molecular and Cellular Biology, Volume 22, Issue 10 (2002)

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Gene Expression

Article
Human U4/U6.U5 and U4atac/U6atac.U5 Tri-snRNPs Exhibit Similar Protein Compositions
Claudia Schneider, Cindy L. Will, Olga V. Makarova, Evgeny M. Makarov & Reinhard Lührmann
Pages: 3219-3229
Published online: 27 Mar 2023
AbstractforHuman U4/U6.U5 and U4atac/U6atac.U5 Tri-snRNPs Exhibit Similar Protein Compositions | Full Text | References | PDF (306.9 KB)
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Mammalian Genetic Models With Minimal Or Complex Phenotypes

Article
Grap Negatively Regulates T-Cell Receptor-Elicited Lymphocyte Proliferation and Interleukin-2 Induction
Randy Shen, Ying-Bin Ouyang, Cheng-Kui Qu, Andres Alonso, Lindsey Sperzel, Tomas Mustelin, Mark H. Kaplan & Gen-Sheng Feng
Pages: 3230-3236
Published online: 27 Mar 2023
AbstractforGrap Negatively Regulates T-Cell Receptor-Elicited Lymphocyte Proliferation and Interleukin-2 Induction | Full Text | References | PDF (233.3 KB)
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Article
A Testicular Germ Cell-Associated Serine-Threonine Kinase, MAK, Is Dispensable for Sperm Formation
Yoichi Shinkai, Hideo Satoh, Naoki Takeda, Mikiko Fukuda, Emiko Chiba, Tomoya Kato, Takashi Kuramochi & Yoshihiko Araki
Pages: 3276-3280
Published online: 27 Mar 2023
AbstractforA Testicular Germ Cell-Associated Serine-Threonine Kinase, MAK, Is Dispensable for Sperm Formation | Full Text | References | PDF (178 KB)
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Article
Generation and Characterization of Smac/DIABLO-Deficient Mice
Hitoshi Okada, Woong-Kyung Suh, Jianping Jin, Minna Woo, Chunying Du, Andrew Elia, Gordon S. Duncan, Andrew Wakeham, Annick Itie, Scott W. Lowe, Xiaodong Wang & Tak W. Mak
Pages: 3509-3517
Published online: 27 Mar 2023
AbstractforGeneration and Characterization of Smac/DIABLO-Deficient Mice | Full Text | References | PDF (461 KB)
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Article
Fliih, a Gelsolin-Related Cytoskeletal Regulator Essential for Early Mammalian Embryonic Development
Hugh D. Campbell, Shelley Fountain, Ian S. McLennan, Leise A. Berven, Michael F. Crouch, Deborah A. Davy, Jane A. Hooper, Kynan Waterford, Ken-Shiung Chen, James R. Lupski, Birgit Ledermann, Ian G. Young & Klaus I. Matthaei
Pages: 3518-3526
Published online: 27 Mar 2023
AbstractforFliih, a Gelsolin-Related Cytoskeletal Regulator Essential for Early Mammalian Embryonic Development | Full Text | References | PDF (624.8 KB)
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Cell Growth and Development

Article
Cyclic AMP-Dependent Kinase Regulates Raf-1 Kinase Mainly by Phosphorylation of Serine 259
Amardeep S. Dhillon, Claire Pollock, Helge Steen, Peter E. Shaw, Harald Mischak & Walter Kolch
Pages: 3237-3246
Published online: 27 Mar 2023
AbstractforCyclic AMP-Dependent Kinase Regulates Raf-1 Kinase Mainly by Phosphorylation of Serine 259 | Full Text | References | PDF (412.1 KB)
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Article
c-Abl Tyrosine Kinase Regulates the Human Rad9 Checkpoint Protein in Response to DNA Damage
Kiyotsugu Yoshida, Kiyoshi Komatsu, Hong-Gang Wang & Donald Kufe
Pages: 3292-3300
Published online: 27 Mar 2023
Abstractforc-Abl Tyrosine Kinase Regulates the Human Rad9 Checkpoint Protein in Response to DNA Damage | Full Text | References | PDF (384.3 KB)
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Article
Poly(A)-Binding Protein Acts in Translation Termination via Eukaryotic Release Factor 3 Interaction and Does Not Influence [PSI+] Propagation
Bertrand Cosson, Anne Couturier, Svetlana Chabelskaya, Denis Kiktev, Sergey Inge-Vechtomov, Michel Philippe & Galina Zhouravleva
Pages: 3301-3315
Published online: 27 Mar 2023
AbstractforPoly(A)-Binding Protein Acts in Translation Termination via Eukaryotic Release Factor 3 Interaction and Does Not Influence [PSI+] Propagation | Full Text | References | PDF (410.5 KB)
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Article
Regulation of Jak2 through the Ubiquitin-Proteasome Pathway Involves Phosphorylation of Jak2 on Y1007 and Interaction with SOCS-1
Daniela Ungureanu, Pipsa Saharinen, Ilkka Junttila, Douglas J. Hilton & Olli Silvennoinen
Pages: 3316-3326
Published online: 27 Mar 2023
AbstractforRegulation of Jak2 through the Ubiquitin-Proteasome Pathway Involves Phosphorylation of Jak2 on Y1007 and Interaction with SOCS-1 | Full Text | References | PDF (418 KB)
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Article
Physical Interaction of Human T-Cell Leukemia Virus Type 1 Tax with Cyclin-Dependent Kinase 4 Stimulates the Phosphorylation of Retinoblastoma Protein
Kerstin Haller, Yalin Wu, Elisabeth Derow, Iris Schmitt, Kuan-Teh Jeang & Ralph Grassmann
Pages: 3327-3338
Published online: 27 Mar 2023
AbstractforPhysical Interaction of Human T-Cell Leukemia Virus Type 1 Tax with Cyclin-Dependent Kinase 4 Stimulates the Phosphorylation of Retinoblastoma Protein | Full Text | References | PDF (614.7 KB)
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Article
mRTVP-1, a Novel p53 Target Gene with Proapoptotic Activities
Chengzhen Ren, Likun Li, Alexei A. Goltsov, Terry L. Timme, Salahaldin A. Tahir, Jianxiang Wang, Laura Garza, A. Craig Chinault & Timothy C. Thompson
Pages: 3345-3357
Published online: 27 Mar 2023
AbstractformRTVP-1, a Novel p53 Target Gene with Proapoptotic Activities | Full Text | References | PDF (951.2 KB)
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Article
Androgen Receptor Acetylation Governs trans Activation and MEKK1-Induced Apoptosis without Affecting In Vitro Sumoylation and trans-Repression Function
Maofu Fu, Chenguang Wang, Jian Wang, Xueping Zhang, Toshiyuki Sakamaki, Y. G. Yeung, Chawnshang Chang, Torsten Hopp, Suzanne A. W. Fuqua, Ellis Jaffray, Ron T. Hay, Jorma J. Palvimo, Olli A. Jänne & Richard G. Pestell
Pages: 3373-3388
Published online: 27 Mar 2023
AbstractforAndrogen Receptor Acetylation Governs trans Activation and MEKK1-Induced Apoptosis without Affecting In Vitro Sumoylation and trans-Repression Function | Full Text | References | PDF (834.8 KB)
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Article
Sequential Activation of the MEK-Extracellular Signal-Regulated Kinase and MKK3/6-p38 Mitogen-Activated Protein Kinase Pathways Mediates Oncogenic ras-Induced Premature Senescence
Weiping Wang, Joan X. Chen, Rong Liao, Qingdong Deng, Jennifer J. Zhou, Shuang Huang & Peiqing Sun
Pages: 3389-3403
Published online: 27 Mar 2023
AbstractforSequential Activation of the MEK-Extracellular Signal-Regulated Kinase and MKK3/6-p38 Mitogen-Activated Protein Kinase Pathways Mediates Oncogenic ras-Induced Premature Senescence | Full Text | References | PDF (823.7 KB)
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Article
Low-Molecular-Weight Protein Tyrosine Phosphatase Is a Positive Component of the Fibroblast Growth Factor Receptor Signaling Pathway
Eui Kyun Park, Neil Warner, Kathleen Mood, Tony Pawson & Ira O. Daar
Pages: 3404-3414
Published online: 27 Mar 2023
AbstractforLow-Molecular-Weight Protein Tyrosine Phosphatase Is a Positive Component of the Fibroblast Growth Factor Receptor Signaling Pathway | Full Text | References | PDF (792.8 KB)
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Article
Hsp72 and Stress Kinase c-jun N-Terminal Kinase Regulate the Bid-Dependent Pathway in Tumor Necrosis Factor-Induced Apoptosis
Vladimir L. Gabai, Katsuhide Mabuchi, Dick D. Mosser & Michael Y. Sherman
Pages: 3415-3424
Published online: 27 Mar 2023
AbstractforHsp72 and Stress Kinase c-jun N-Terminal Kinase Regulate the Bid-Dependent Pathway in Tumor Necrosis Factor-Induced Apoptosis | Full Text | References | PDF (586.6 KB)
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Article
AMP-Activated Kinase Regulates Cytoplasmic HuR
Wengong Wang, Jinshui Fan, Xiaoling Yang, Stefanie Fürer-Galban, Isabel Lopez de Silanes, Cayetano von Kobbe, Jia Guo, Steve N. Georas, Fabienne Foufelle, D. Grahame Hardie, David Carling & Myriam Gorospe
Pages: 3425-3436
Published online: 27 Mar 2023
AbstractforAMP-Activated Kinase Regulates Cytoplasmic HuR | Full Text | References | PDF (685.9 KB)
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Article
Cell Cycle Arrest and Apoptosis Induced by Human Polo-Like Kinase 3 Is Mediated through Perturbation of Microtubule Integrity
Qi Wang, Suqing Xie, Jie Chen, Kenji Fukasawa, Ulhas Naik, Frank Traganos, Zbigniew Darzynkiewicz, Meena Jhanwar-Uniyal & Wei Dai
Pages: 3450-3459
Published online: 27 Mar 2023
AbstractforCell Cycle Arrest and Apoptosis Induced by Human Polo-Like Kinase 3 Is Mediated through Perturbation of Microtubule Integrity | Full Text | References | PDF (969.3 KB)
  • 19 Views
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Article
Oncogenic ras and p53 Cooperate To Induce Cellular Senescence
Gerardo Ferbeyre, Elisa de Stanchina, Athena W. Lin, Emmanuelle Querido, Mila E. McCurrach, Gregory J. Hannon & Scott W. Lowe
Pages: 3497-3508
Published online: 27 Mar 2023
AbstractforOncogenic ras and p53 Cooperate To Induce Cellular Senescence | Full Text | References | PDF (962.7 KB)
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Article
Tyrosine Phosphorylation Regulates Alpha II Spectrin Cleavage by Calpain
Gaël Nicolas, Catherine M. Fournier, Colette Galand, Laurence Malbert-Colas, Odile Bournier, Yolande Kroviarski, Monique Bourgeois, Jacques H. Camonis, Didier Dhermy, Bernard Grandchamp & Marie-Christine Lecomte
Pages: 3527-3536
Published online: 27 Mar 2023
AbstractforTyrosine Phosphorylation Regulates Alpha II Spectrin Cleavage by Calpain | Full Text | References | PDF (450.2 KB)
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Transcriptional Regulation

Article
p53 Binds and Activates the Xeroderma Pigmentosum DDB2 Gene in Humans but Not Mice
Thomas Tan & Gilbert Chu
Pages: 3247-3254
Published online: 27 Mar 2023
Abstractforp53 Binds and Activates the Xeroderma Pigmentosum DDB2 Gene in Humans but Not Mice | Full Text | References | PDF (395 KB)
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Article
ATP-Dependent Mobilization of the Glucocorticoid Receptor during Chromatin Remodeling
Terace M. Fletcher, Nianqing Xiao, Gisele Mautino, Christopher T. Baumann, Ronald Wolford, Barbour S. Warren & Gordon L. Hager
Pages: 3255-3263
Published online: 27 Mar 2023
AbstractforATP-Dependent Mobilization of the Glucocorticoid Receptor during Chromatin Remodeling | Full Text | References | PDF (317.2 KB)
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Article
Essential Roles of Bdp1, a Subunit of RNA Polymerase III Initiation Factor TFIIIB, in Transcription and tRNA Processing
Akira Ishiguro, George A. Kassavetis & E. Peter Geiduschek
Pages: 3264-3275
Published online: 27 Mar 2023
AbstractforEssential Roles of Bdp1, a Subunit of RNA Polymerase III Initiation Factor TFIIIB, in Transcription and tRNA Processing | Full Text | References | PDF (707.3 KB)
  • 34 Views
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Article
Multiple Nucleosome Positioning Sites Regulate the CTCF-Mediated Insulator Function of the H19 Imprinting Control Region†
Meena Kanduri, Chandrasekhar Kanduri, Piero Mariano, Alexander A. Vostrov, Wolfgang Quitschke, Victor Lobanenkov & Rolf Ohlsson
Pages: 3339-3344
Published online: 27 Mar 2023
AbstractforMultiple Nucleosome Positioning Sites Regulate the CTCF-Mediated Insulator Function of the H19 Imprinting Control Region† | Full Text | References | PDF (568.4 KB)
  • 8 Views
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Article
ERAP140, a Conserved Tissue-Specific Nuclear Receptor Coactivator
Wenlin Shao, Shlomit Halachmi & Myles Brown
Pages: 3358-3372
Published online: 27 Mar 2023
AbstractforERAP140, a Conserved Tissue-Specific Nuclear Receptor Coactivator | Full Text | References | PDF (858.8 KB)
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Article
Alteration of Large-Scale Chromatin Structure by Estrogen Receptor
Anne C. Nye, Ramji R. Rajendran, David L. Stenoien, Michael A. Mancini, Benita S. Katzenellenbogen & Andrew S. Belmont
Pages: 3437-3449
Published online: 27 Mar 2023
AbstractforAlteration of Large-Scale Chromatin Structure by Estrogen Receptor | Full Text | References | PDF (1,023.8 KB)
  • 25 Views
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Article
Gene Control in Germinal Differentiation: Rnf6, a Transcription Regulatory Protein in the Mouse Sertoli Cell
Pascal Lopez, Frédérique Vidal, Luc Martin, Luis A. Lopez-Fernandez, Jean-François Rual, Barry S. Rosen, François Cuzin & Minoo Rassoulzadegan
Pages: 3488-3496
Published online: 27 Mar 2023
AbstractforGene Control in Germinal Differentiation: Rnf6, a Transcription Regulatory Protein in the Mouse Sertoli Cell | Full Text | References | PDF (793.8 KB)
  • 2 Views
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Article
Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator Activity by IκB Kinase
Ray-Chang Wu, Jun Qin, Yoshihiro Hashimoto, Jiemin Wong, Jianming Xu, Sophia Y. Tsai, Ming-Jer Tsai & Bert W. O'Malley
Pages: 3549-3561
Published online: 27 Mar 2023
AbstractforRegulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator Activity by IκB Kinase | Full Text | References | PDF (519.1 KB)
  • 54 Views
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Dna Dynamics and Chromosome Structure

Article
Saccharomyces cerevisiae Mer3 Is a DNA Helicase Involved in Meiotic Crossing Over
Takuro Nakagawa & Richard D. Kolodner
Pages: 3281-3291
Published online: 27 Mar 2023
AbstractforSaccharomyces cerevisiae Mer3 Is a DNA Helicase Involved in Meiotic Crossing Over | Full Text | References | PDF (377.8 KB)
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Article
Mutational Analysis of All Conserved Basic Amino Acids in RAG-1 Reveals Catalytic, Step Arrest, and Joining-Deficient Mutants in the V(D)J Recombinase
Leslie E. Huye, Mary M. Purugganan, Ming-Ming Jiang & David B. Roth
Pages: 3460-3473
Published online: 27 Mar 2023
AbstractforMutational Analysis of All Conserved Basic Amino Acids in RAG-1 Reveals Catalytic, Step Arrest, and Joining-Deficient Mutants in the V(D)J Recombinase | Full Text | References | PDF (882 KB)
  • 10 Views
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Article
Targeting Assay To Study the cis Functions of Human Telomeric Proteins: Evidence for Inhibition of Telomerase by TRF1 and for Activation of Telomere Degradation by TRF2
Katia Ancelin, Michele Brunori, Serge Bauwens, Catherine-Elaine Koering, Christine Brun, Michelle Ricoul, Jean-Patrick Pommier, Laure Sabatier & Eric Gilson
Pages: 3474-3487
Published online: 27 Mar 2023
AbstractforTargeting Assay To Study the cis Functions of Human Telomeric Proteins: Evidence for Inhibition of Telomerase by TRF1 and for Activation of Telomere Degradation by TRF2 | Full Text | References | PDF (627.7 KB)
  • 38 Views
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Article
The Schizosaccharomyces pombe rad60 Gene Is Essential for Repairing Double-Strand DNA Breaks Spontaneously Occurring during Replication and Induced by DNA-Damaging Agents
Takashi Morishita, Yasuhiro Tsutsui, Hiroshi Iwasaki & Hideo Shinagawa
Pages: 3537-3548
Published online: 27 Mar 2023
AbstractforThe Schizosaccharomyces pombe rad60 Gene Is Essential for Repairing Double-Strand DNA Breaks Spontaneously Occurring during Replication and Induced by DNA-Damaging Agents | Full Text | References | PDF (623.7 KB)
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Errata

Correction
Enumeration of the Simian Virus 40 Early Region Elements Necessary for Human Cell Transformation
Page: 3562
Published online: 27 Mar 2023
CitationforEnumeration of the Simian Virus 40 Early Region Elements Necessary for Human Cell Transformation | Full Text | PDF (16.7 KB)
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Free Access

Author's Correction

Correction
Role of the 3′ Splice Site in U12-Dependent Intron Splicing
Page: 3563
Published online: 27 Mar 2023
CitationforRole of the 3′ Splice Site in U12-Dependent Intron Splicing | Full Text | PDF (18.4 KB)
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