Molecular and Cellular Biology, Volume 34, Issue 7 (2014)

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Molecular and Cellular Biology, Volume 34, Issue 7 (2014)

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Articles of Significant Interest Selected from This Issue by the Editors
Page: 1187
Published online: 20 Mar 2023
CitationforArticles of Significant Interest Selected from This Issue by the Editors | Full Text | PDF (68.4 KB)
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Article
The Capable ABL: What Is Its Biological Function?
Jean Y. J. Wang
Pages: 1188-1197
Published online: 20 Mar 2023
AbstractforThe Capable ABL: What Is Its Biological Function? | Full Text | References | PDF (828.9 KB)
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Articles

Article
Activation of the Proapoptotic Bcl-2 Protein Bax by a Small Molecule Induces Tumor Cell Apoptosis
Guoping Zhao, Yanglong Zhu, Colins O. Eno, Yanlong Liu, Lynn DeLeeuw, Joseph A. Burlison, Jonathan B. Chaires, John O. Trent & Chi Li
Pages: 1198-1207
Published online: 20 Mar 2023
AbstractforActivation of the Proapoptotic Bcl-2 Protein Bax by a Small Molecule Induces Tumor Cell Apoptosis | Full Text | References | PDF (1.5 MB) | Supplemental
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Article
Loss of von Hippel-Lindau Protein (VHL) Increases Systemic Cholesterol Levels through Targeting Hypoxia-Inducible Factor 2α and Regulation of Bile Acid Homeostasis
Sadeesh K. Ramakrishnan, Matthew Taylor, Aijuan Qu, Sung-Hoon Ahn, Madathilparambil V. Suresh, Krishnan Raghavendran, Frank J. Gonzalez & Yatrik M. Shah
Pages: 1208-1220
Published online: 20 Mar 2023
AbstractforLoss of von Hippel-Lindau Protein (VHL) Increases Systemic Cholesterol Levels through Targeting Hypoxia-Inducible Factor 2α and Regulation of Bile Acid Homeostasis | Full Text | References | PDF (3.4 MB) | Supplemental
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Article
S/T Phosphorylation of DLL1 Is Required for Full Ligand Activity In Vitro but Dispensable for DLL1 Function In Vivo during Embryonic Patterning and Marginal Zone B Cell Development
Eike-Benjamin Braune, Karin Schuster-Gossler, Marcin Lyszkiewicz, Katrin Serth, Kristina Preusse, Johannes Madlung, Boris Macek, Andreas Krueger & Achim Gossler
Pages: 1221-1233
Published online: 20 Mar 2023
AbstractforS/T Phosphorylation of DLL1 Is Required for Full Ligand Activity In Vitro but Dispensable for DLL1 Function In Vivo during Embryonic Patterning and Marginal Zone B Cell Development | Full Text | References | PDF (2.2 MB) | Supplemental
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Article
Ligand Binding Shifts Highly Mobile Retinoid X Receptor to the Chromatin-Bound State in a Coactivator-Dependent Manner, as Revealed by Single-Cell Imaging
Peter Brazda, Jan Krieger, Bence Daniel, David Jonas, Tibor Szekeres, Jörg Langowski, Katalin Tóth, Laszlo Nagy & György Vámosi
Pages: 1234-1245
Published online: 20 Mar 2023
AbstractforLigand Binding Shifts Highly Mobile Retinoid X Receptor to the Chromatin-Bound State in a Coactivator-Dependent Manner, as Revealed by Single-Cell Imaging | Full Text | References | PDF (3 MB) | Supplemental
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Article
Activation of p53 Transcriptional Activity by SMRT: a Histone Deacetylase 3-Independent Function of a Transcriptional Corepressor
Anbu Karani Adikesavan, Sudipan Karmakar, Patricia Pardo, Liguo Wang, Shuang Liu, Wei Li & Carolyn L. Smith
Pages: 1246-1261
Published online: 20 Mar 2023
AbstractforActivation of p53 Transcriptional Activity by SMRT: a Histone Deacetylase 3-Independent Function of a Transcriptional Corepressor | Full Text | References | PDF (1.1 MB)
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Article
The E3 Ubiquitin Ligase MARCH6 Degrades Squalene Monooxygenase and Affects 3-Hydroxy-3-Methyl-Glutaryl Coenzyme A Reductase and the Cholesterol Synthesis Pathway
Noam Zelcer, Laura J. Sharpe, Anke Loregger, Ika Kristiana, Emma C. L. Cook, Lisa Phan, Julian Stevenson & Andrew J. Brown
Pages: 1262-1270
Published online: 20 Mar 2023
AbstractforThe E3 Ubiquitin Ligase MARCH6 Degrades Squalene Monooxygenase and Affects 3-Hydroxy-3-Methyl-Glutaryl Coenzyme A Reductase and the Cholesterol Synthesis Pathway | Full Text | References | PDF (1.4 MB) | Supplemental
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Article
Insulin Stimulates Syntaxin4 SNARE Complex Assembly via a Novel Regulatory Mechanism
Dimitrios Kioumourtzoglou, Gwyn W. Gould & Nia J. Bryant
Pages: 1271-1279
Published online: 20 Mar 2023
AbstractforInsulin Stimulates Syntaxin4 SNARE Complex Assembly via a Novel Regulatory Mechanism | Full Text | References | PDF (1.7 MB) | Supplemental
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Article
Yin Yang 1 Is a Repressor of Glutamate Transporter EAAT2, and It Mediates Manganese-Induced Decrease of EAAT2 Expression in Astrocytes
Pratap Karki, Anton Webb, Keisha Smith, James Johnson Jr., Kyuwon Lee, Deok-Soo Son, Michael Aschner & Eunsook Lee
Pages: 1280-1289
Published online: 20 Mar 2023
AbstractforYin Yang 1 Is a Repressor of Glutamate Transporter EAAT2, and It Mediates Manganese-Induced Decrease of EAAT2 Expression in Astrocytes | Full Text | References | PDF (1.9 MB)
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Article
Deregulation of Pancreas-Specific Oxidoreductin ERO1β in the Pathogenesis of Diabetes Mellitus
Motoharu Awazawa, Takashi Futami, Michinori Sakada, Kazuma Kaneko, Mitsuru Ohsugi, Keizo Nakaya, Ai Terai, Ryo Suzuki, Masato Koike, Yasuo Uchiyama, Takashi Kadowaki & Kohjiro Ueki
Pages: 1290-1299
Published online: 20 Mar 2023
AbstractforDeregulation of Pancreas-Specific Oxidoreductin ERO1β in the Pathogenesis of Diabetes Mellitus | Full Text | References | PDF (4.1 MB)
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Article
Cytoplasmic Poly(A) Binding Protein C4 Serves a Critical Role in Erythroid Differentiation
Hemant K. Kini, Jian Kong & Stephen A. Liebhaber
Pages: 1300-1309
Published online: 20 Mar 2023
AbstractforCytoplasmic Poly(A) Binding Protein C4 Serves a Critical Role in Erythroid Differentiation | Full Text | References | PDF (1,009.6 KB)
  • 188 Views
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Article
Sept6 Is Required for Ciliogenesis in Kupffer's Vesicle, the Pronephros, and the Neural Tube during Early Embryonic Development
Gang Zhai, Qilin Gu, Jiangyan He, Qiyong Lou, Xiaowen Chen, Xia Jin, Erfei Bi & Zhan Yin
Pages: 1310-1321
Published online: 20 Mar 2023
AbstractforSept6 Is Required for Ciliogenesis in Kupffer's Vesicle, the Pronephros, and the Neural Tube during Early Embryonic Development | Full Text | References | PDF (3.8 MB)
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Article
Mechanism Underlying IκB Kinase Activation Mediated by the Linear Ubiquitin Chain Assembly Complex
Hiroaki Fujita, Simin Rahighi, Mariko Akita, Ryuichi Kato, Yoshiteru Sasaki, Soichi Wakatsuki & Kazuhiro Iwai
Pages: 1322-1335
Published online: 20 Mar 2023
AbstractforMechanism Underlying IκB Kinase Activation Mediated by the Linear Ubiquitin Chain Assembly Complex | Full Text | References | PDF (3.3 MB)
  • 98 Views
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Article
Proteasome Failure Promotes Positioning of Lysosomes around the Aggresome via Local Block of Microtubule-Dependent Transport
Nava Zaarur, Anatoli B. Meriin, Eloy Bejarano, Xiaobin Xu, Vladimir L. Gabai, Ana Maria Cuervo & Michael Y. Sherman
Pages: 1336-1348
Published online: 20 Mar 2023
AbstractforProteasome Failure Promotes Positioning of Lysosomes around the Aggresome via Local Block of Microtubule-Dependent Transport | Full Text | References | PDF (2.5 MB) | Supplemental
  • 126 Views
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Article
TRF2-Tethered TIN2 Can Mediate Telomere Protection by TPP1/POT1
David Frescas & Titia de Lange
Pages: 1349-1362
Published online: 20 Mar 2023
AbstractforTRF2-Tethered TIN2 Can Mediate Telomere Protection by TPP1/POT1 | Full Text | References | PDF (5.3 MB)
  • 65 Views
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Article
Stat5 Regulates the Phosphatidylinositol 3-Kinase/Akt1 Pathway during Mammary Gland Development and Tumorigenesis
Jeffrey W. Schmidt, Barbara L. Wehde, Kazuhito Sakamoto, Aleata A. Triplett, Steven M. Anderson, Philip N. Tsichlis, Gustavo Leone & Kay-Uwe Wagner
Pages: 1363-1377
Published online: 20 Mar 2023
AbstractforStat5 Regulates the Phosphatidylinositol 3-Kinase/Akt1 Pathway during Mammary Gland Development and Tumorigenesis | Full Text | References | PDF (5.3 MB)
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Author Correction

Correction
SirT3 Regulates the Mitochondrial Unfolded Protein Response
Page: 1378
Published online: 20 Mar 2023
CitationforSirT3 Regulates the Mitochondrial Unfolded Protein Response | Full Text | PDF (62.1 KB)
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Free Access

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Editorial Board
Page: 1
Published online: 20 Mar 2023
CitationforEditorial Board | Full Text | PDF (62.9 KB)
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