Journal of Toxicology and Environmental Health, Part A, Volume 77, Issue 22-24 (2014)

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Journal of Toxicology and Environmental Health, Part A, Volume 77, Issue 22-24 (2014)

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Molecular Mechanism of Toxic Responses and Risk Assessment

Original Articles

Article
The No-Observed-Adverse-Effect Level (NOAEL) of Baby Aloe Powder (BAP) for Nutraceutical Application Based Upon Toxicological Evaluation
Seung Jun Kwack, Seon-Gil Do, Young Woo Kim, Yeon-Joo Kim, Hyo-Min Gwak, Hyun Jong Park, Taehyun Roh, Min Kyung Shin, Seong Kwang Lim, Hyung Sik Kim & Byung-Mu Lee
Pages: 1319-1331
Published online: 24 Oct 2014
AbstractforThe No-Observed-Adverse-Effect Level (NOAEL) of Baby Aloe Powder (BAP) for Nutraceutical Application Based Upon Toxicological Evaluation | Full Text | References | PDF (268.7 KB)
  • 241 Views
  • 3 CrossRef citations
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Article
Anti-Inflammatory Effect of Glycosaminoglycan Derived From Gryllus bimaculatus (A Type of Cricket, Insect) on Adjuvant-Treated Chronic Arthritis Rat Model
Mi Young Ahn, Jea Woong Han, Jae Sam Hwang, Eun Young Yun & Byung Mu Lee
Pages: 1332-1345
Published online: 24 Oct 2014
AbstractforAnti-Inflammatory Effect of Glycosaminoglycan Derived From Gryllus bimaculatus (A Type of Cricket, Insect) on Adjuvant-Treated Chronic Arthritis Rat Model | Full Text | References | PDF (648.3 KB)
  • 485 Views
  • 36 CrossRef citations
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Article
Nephrotoxic Potential and Toxicokinetics of Melamine Combined with Cyanuric Acid in Rats
Ghee Hwan Kim, Mi Jeong Kang, Keumhan Noh, Do Gyeong Oh, Wonku Kang, Hye Gwang Jeong, Kwang Youl Lee, Hangun Kim, Hyung Sik Kim & Tae Cheon Jeong
Pages: 1346-1358
Published online: 24 Oct 2014
AbstractforNephrotoxic Potential and Toxicokinetics of Melamine Combined with Cyanuric Acid in Rats | Full Text | References | PDF (505.3 KB)
  • 216 Views
  • 9 CrossRef citations
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Article
Determination of Polycyclic Aromatic Hydrocarbon (PAH) Content and Risk Assessment From Edible Oils in Korea
Bomi Kang, Byung-Mu Lee & Han-Seung Shin
Pages: 1359-1371
Published online: 24 Oct 2014
AbstractforDetermination of Polycyclic Aromatic Hydrocarbon (PAH) Content and Risk Assessment From Edible Oils in Korea | Full Text | References | PDF (215.4 KB)
  • 443 Views
  • 32 CrossRef citations
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Article
Negligible Pharmacokinetic Interaction of Red Ginseng and Antihypertensive Agent Amlodipine in Sprague-Dawley Rats
Sung Ha Ryu, Ji Won Kim, Yong Soon Kim, Seung-Ho Lee, Yong-Baik Cho, Hyo Keun Lee, Yoon Gyoon Kim, Woo-Sik Jeong & Kyu-Bong Kim
Pages: 1372-1383
Published online: 24 Oct 2014
AbstractforNegligible Pharmacokinetic Interaction of Red Ginseng and Antihypertensive Agent Amlodipine in Sprague-Dawley Rats | Full Text | References | PDF (380.4 KB)
  • 209 Views
  • 12 CrossRef citations
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Article
Evaluation of Cadmium-Induced Nephrotoxicity Using Urinary Metabolomic Profiles in Sprague-Dawley Male Rats
Yu Kyung Lee, Eun Young Park, Shiwon Kim, Ji Yeon Son, Tae Hyung Kim, Won Gu Kang, Tae Chun Jeong, Kyu-Bong Kim, Seung Jun Kwack, Jaewon Lee, Suhkmann Kim, Byung-Mu Lee & Hyung Sik Kim
Pages: 1384-1398
Published online: 24 Oct 2014
AbstractforEvaluation of Cadmium-Induced Nephrotoxicity Using Urinary Metabolomic Profiles in Sprague-Dawley Male Rats | Full Text | References | PDF (654.6 KB)
  • 596 Views
  • 38 CrossRef citations
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Article
Potential Toxicity of Differential Functionalized Multiwalled Carbon Nanotubes (MWCNT) in Human Cell Line (BEAS2B) and Caenorhabditis elegans
Nivedita Chatterjee, JiSu Yang, Hyun-Mi Kim, Eunhye Jo, Phil-Je Kim, Kyunghee Choi & Jinhee Choi
Pages: 1399-1408
Published online: 24 Oct 2014
AbstractforPotential Toxicity of Differential Functionalized Multiwalled Carbon Nanotubes (MWCNT) in Human Cell Line (BEAS2B) and Caenorhabditis elegans | Full Text | References | PDF (356.8 KB)
  • 575 Views
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Article
Directed-Evolution Analysis of Human Cytochrome P450 2A6 for Enhanced Enzymatic Catalysis
Hwayoun Lee, Joo-Hwan Kim, Songhee Han, Young-Ran Lim, Hyoung-Goo Park, Young-Jin Chun, Sung-Woo Park & Donghak Kim
Pages: 1409-1418
Published online: 24 Oct 2014
AbstractforDirected-Evolution Analysis of Human Cytochrome P450 2A6 for Enhanced Enzymatic Catalysis | Full Text | References | PDF (287.4 KB)
  • 292 Views
  • 3 CrossRef citations
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Article
Enantioselective N-Demethylation and Hydroxylation of Sibutramine in Human Liver Microsomes and Recombinant Cytochrome P-450 Isoforms
Dhananjay D. Shinde, Min-Jung Kim, Eun-Sook Jeong, Yang-Weon Kim, Ji-Woo Lee, Jae-Gook Shin & Dong-Hyun Kim
Pages: 1419-1430
Published online: 24 Oct 2014
AbstractforEnantioselective N-Demethylation and Hydroxylation of Sibutramine in Human Liver Microsomes and Recombinant Cytochrome P-450 Isoforms | Full Text | References | PDF (448 KB)
  • 163 Views
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Article
A One-Generation Reproductive Toxicity Study of 3,4-Methylenedioxy-N-Methamphetamine (MDMA, Ecstasy), an Amphetamine Derivative, in C57BL/6 Mice
Seung Jun Kwack, Kyung Sik Yoon, Seong Kwang Lim, Hyo-min Gwak, Ji Yun Kim, Yoon Mi Um, Jung Dae Lee, Ji Hyeon Hyeon, Yeon Joo Kim, Hyung Sik Kim & Byung-Mu Lee
Pages: 1431-1442
Published online: 24 Oct 2014
AbstractforA One-Generation Reproductive Toxicity Study of 3,4-Methylenedioxy-N-Methamphetamine (MDMA, Ecstasy), an Amphetamine Derivative, in C57BL/6 Mice | Full Text | References | PDF (348.6 KB)
  • 287 Views
  • 6 CrossRef citations
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Article
Knockdown of Clusterin Expression Increases the In Vitro Sensitivity of Human Prostate Cancer Cells to Paclitaxel
Young-Jin Chun
Pages: 1443-1450
Published online: 24 Oct 2014
AbstractforKnockdown of Clusterin Expression Increases the In Vitro Sensitivity of Human Prostate Cancer Cells to Paclitaxel | Full Text | References | PDF (254.9 KB)
  • 173 Views
  • 9 CrossRef citations
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Article
Comparative Efficacy and Bioequivalence of Novel H1-Antihistamine Bepotastine Salts (Nicotinate and Salicylate)
Duck Soo Lim, Yoo Seok Youn, Seung Jun Kwack, Hyo Min Kwak, Seong Kwang Lim, Ji Yun Kim, Yoon Mi Um, Jung Dae Lee, Ji Hyeon Hyeon, Yeon Joo Kim, Hyung Sik Kim & Byung-Mu Lee
Pages: 1451-1466
Published online: 24 Oct 2014
AbstractforComparative Efficacy and Bioequivalence of Novel H1-Antihistamine Bepotastine Salts (Nicotinate and Salicylate) | Full Text | References | PDF (459.4 KB)
  • 217 Views
  • 2 CrossRef citations
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Article
Auranofin Promotes Mitochondrial Apoptosis by Inducing Annexin A5 Expression and Translocation in Human Prostate Cancer Cells
Nahee Park & Young-Jin Chun
Pages: 1467-1476
Published online: 24 Oct 2014
AbstractforAuranofin Promotes Mitochondrial Apoptosis by Inducing Annexin A5 Expression and Translocation in Human Prostate Cancer Cells | Full Text | References | PDF (477.6 KB)
  • 340 Views
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Article
Effects of Environmental Temperature Change on Mercury Absorption in Aquatic Organisms with Respect to Climate Warming
Eun Chul Pack, Chun Huem Kim, Seung Ha Lee, Chae Hee Lim, Dea Gwan Sung, Mee Hye Kim, Ki Hwan Park, Soon-Sun Hong, Kyung Min Lim, Dal Woong Choi & Suhng Wook Kim
Pages: 1477-1490
Published online: 24 Oct 2014
AbstractforEffects of Environmental Temperature Change on Mercury Absorption in Aquatic Organisms with Respect to Climate Warming | Full Text | References | PDF (394.9 KB)
  • 854 Views
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Article
Potential Application of Benzo(a)Pyrene-Associated Adducts (Globin or Lipid) as Blood Biomarkers for Target Organ Exposure and Human Risk Assessment
Seung Jun Kwack, Dae Young Kim, Yeon Joo Kim, Tae Hyun Roh, Seul Min Choi, Duck Soo Lim, Han-Seung Shin, Hyung Sik Kim & Byung-Mu Lee
Pages: 1491-1501
Published online: 24 Oct 2014
AbstractforPotential Application of Benzo(a)Pyrene-Associated Adducts (Globin or Lipid) as Blood Biomarkers for Target Organ Exposure and Human Risk Assessment | Full Text | References | PDF (400.7 KB)
  • 197 Views
  • 7 CrossRef citations
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Article
Risk Assessment of Volatile Organic Compounds Benzene, Toluene, Ethylbenzene, and Xylene (BTEX) in Consumer Products
Seong Kwang Lim, Han Seung Shin, Kyung Sil Yoon, Seung Jun Kwack, Yoon Mi Um, Ji Hyeon Hyeon, Hyo Min Kwak, Ji Yun Kim, Tae Hyung Kim, Yeon Joo Kim, Tae Hyun Roh, Duck Soo Lim, Min Kyung Shin, Seul Min Choi, Hyung Sik Kim & Byung-Mu Lee
Pages: 1502-1521
Published online: 24 Oct 2014
AbstractforRisk Assessment of Volatile Organic Compounds Benzene, Toluene, Ethylbenzene, and Xylene (BTEX) in Consumer Products | Full Text | References | PDF (307.1 KB)
  • 2015 Views
  • 75 CrossRef citations
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Article
Inhibitory Effects of Cedrol, β-Cedrene, and Thujopsene on Cytochrome P450 Enzyme Activities in Human Liver Microsomes
Hyeon-Uk Jeong, Soon-Sang Kwon, Tae Yeon Kong, Ju Hyun Kim & Hye Suk Lee
Pages: 1522-1532
Published online: 24 Oct 2014
AbstractforInhibitory Effects of Cedrol, β-Cedrene, and Thujopsene on Cytochrome P450 Enzyme Activities in Human Liver Microsomes | Full Text | References | PDF (488.7 KB)
  • 562 Views
  • 31 CrossRef citations
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