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James S. Bus, B. Bhaskar Gollapudi & Gordon C. Hard. (2022) Methyl-tert-butyl ether (MTBE): integration of rat and mouse carcinogenicity data with mode of action and human and rodent bioassay dosimetry and toxicokinetics indicates MTBE is not a plausible human carcinogen. Journal of Toxicology and Environmental Health, Part B 25:4, pages 135-161.
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Tingting Zhang, Linlin Pan, Yu Cao, Nanyang Liu, Wei Wei & Hao Li. (2020) Identifying the Mechanisms and Molecular Targets of Yizhiqingxin Formula on Alzheimer’s Disease: Coupling Network Pharmacology with GEO Database. Pharmacogenomics and Personalized Medicine 13, pages 487-502.
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Samuel M. Cohen, Yan Zhongyu & James S. Bus. (2020) Relevance of mouse lung tumors to human risk assessment. Journal of Toxicology and Environmental Health, Part B 23:5, pages 214-241.
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B. H. Neal, J. Bus, M. S. Marty, K. Coady, A. Williams, J. Staveley & J. C. Lamb. (2017) Weight-of-the-evidence evaluation of 2,4-D potential for interactions with the estrogen, androgen and thyroid pathways and steroidogenesis. Critical Reviews in Toxicology 47:5, pages 352-408.
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Lisa M. Sweeney, Janet E. Kester, Christopher R. Kirman, P. Robinan Gentry, Marcy I. Banton, James S. Bus & Michael L. Gargas. (2015) Risk assessments for chronic exposure of children and prospective parents to ethylbenzene (CAS No. 100-41-4). Critical Reviews in Toxicology 45:8, pages 662-726.
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Claire Terry, Reza J. Rasoulpour, Shakil Saghir, Sue Marty, B. Bhaskar Gollapudi & Richard Billington. (2014) Application of a novel integrated toxicity testing strategy incorporating “3R” principles of animal research to evaluate the safety of a new agrochemical sulfoxaflor. Critical Reviews in Toxicology 44:sup2, pages 1-14.
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Joachim
D. Pleil. (2012) Categorizing Biomarkers of the Human Exposome and Developing Metrics for Assessing Environmental Sustainability. Journal of Toxicology and Environmental Health, Part B 15:4, pages 264-280.
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Elaine
A. Cohen Hubal, Ann Richard, Lesa Aylward, Steve Edwards, Jane Gallagher, Michael-Rock Goldsmith, Sastry Isukapalli, Rogelio Tornero-Velez, Eric Weber & Robert Kavlock. (2010) Advancing Exposure Characterization for Chemical Evaluation and Risk Assessment. Journal of Toxicology and Environmental Health, Part B 13:2-4, pages 299-313.
Read now
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Richard Billington, Richard W. Lewis, Jyotigna M. Mehta & Ian Dewhurst. (2010) The mouse carcinogenicity study is no longer a scientifically justifiable core data requirement for the safety assessment of pesticides. Critical Reviews in Toxicology 40:1, pages 35-49.
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Lorenz R. Rhomberg, Karl Baetcke, Jerry Blancato, James Bus, Samuel Cohen, Rory Conolly, Rakesh Dixit, John Doe, Karen Ekelman, Penny Fenner-Crisp, Paul Harvey, Dale Hattis, Abigail Jacobs, David Jacobson-Kram, Tom Lewandowski, Robert Liteplo, Olavi Pelkonen, Jerry Rice, Diana Somers, Angelo Turturro, Webster West & Stephen Olin. (2007) Issues in the Design and Interpretation of Chronic Toxicity and Carcinogenicity Studies in Rodents: Approaches to Dose Selection. Critical Reviews in Toxicology 37:9, pages 729-837.
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Ralph L. Cooper, James C. Lamb$suffix/text()$suffix/text(), Sue M. Barlow, Karin Bentley, Angela M. Brady, Nancy G. Doerrer, David L. Eisenbrandt, Penelope A. Fenner-Crisp, Ronald N. Hines, Lorraine F. H. Irvine, Carole A. Kimmel, Herman Koeter, Abby A. Li, Susan L. Makris, Larry P. Sheets, Gerrit J. A. Speijers & Karen E. Whitby. (2006) A Tiered Approach to Life Stages Testing for Agricultural Chemical Safety Assessment. Critical Reviews in Toxicology 36:1, pages 69-98.
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John E. Doe, Alan R. Boobis, Ann Blacker, Vicki Dellarco, Nancy G. Doerrer, Claire Franklin, Jay I. Goodman, Joel M. Kronenberg, Richard Lewis, Ernest E. McConnell, Thierry Mercier, Angelo Moretto, Canice Nolan, Stephanie Padilla, Whang Phang, Roland Solecki, Lorraine Tilbury, Bennard van Ravenzwaay & Douglas C. Wolf. (2006) A Tiered Approach to Systemic Toxicity Testing for Agricultural Chemical Safety Assessment. Critical Reviews in Toxicology 36:1, pages 37-68.
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Neil G. Carmichael, Hugh A. Barton, Alan R. Boobis, Ralph L. Cooper, Vicki L. Dellarco, Nancy G. Doerrer, Penelope A. Fenner-Crisp, John E. Doe, James C. Lamb$suffix/text()$suffix/text() & Timothy P. Pastoor. (2006) Agricultural Chemical Safety Assessment: A Multisector Approach to the Modernization of Human Safety Requirements. Critical Reviews in Toxicology 36:1, pages 1-7.
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H. A. Barton, J. Tang, H. A. Barton, J. Tang, Y. M. Sey, J. P. Stanko, R. N. Murrell, H. A. Barton, J. Tang, Y. M. Sey, J. P. Stanko, R. N. Murrell, J. C. Rockett, H. A. Barton, J. Tang, Y. M. Sey, J. P. Stanko, R. N. Murrell, J. C. Rockett & D. J. Dix. (2006) Metabolism of myclobutanil and triadimefon by human and rat cytochrome P450 enzymes and liver microsomes. Xenobiotica 36:9, pages 793-806.
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Articles from other publishers (95)
Durgalakshmi Rajendran & Natarajan Chandrasekaran. (2023) Journey of micronanoplastics with blood components. RSC Advances 13:45, pages 31435-31459.
Crossref
Crossref
Tara J. Bowen, Andrew D. Southam, Andrew R. Hall, Ralf J. M. Weber, Gavin R. Lloyd, Ruth Macdonald, Amanda Wilson, Amy Pointon & Mark R. Viant. (2023) Simultaneously discovering the fate and biochemical effects of pharmaceuticals through untargeted metabolomics. Nature Communications 14:1.
Crossref
Crossref
Anne E. Loccisano, Elaine Freeman, Adriana Doi, Markus Frericks, Ivana Fegert, Eric Fabian & Brandy Riffle. (2023) A new approach methodology using kinetically-derived maximum dose levels in risk assessment – A case study with afidopyropen. Regulatory Toxicology and Pharmacology 142, pages 105429.
Crossref
Crossref
Chenglong Cheng, Qiang Wang, Yurong Huang, Qiuyun Xue, Yuting Wang, Peng Wu, Faxue Liao & Chenggui Miao. (2023) Gandouling inhibits hepatic fibrosis in Wilson's disease through Wnt-1/β-catenin signaling pathway. Journal of Ethnopharmacology 311, pages 116445.
Crossref
Crossref
Shakil A. Saghir, Donald H. Ewert & Rais A. Ansari. 2003. Patty's Toxicology. Patty's Toxicology
1
9
.
Douglas C Wolf, Yadvinder Bhuller, Rhian Cope, Marco Corvaro, Richard A Currie, John Doe, Adriana Doi, Gina Hilton, Jyotigna Mehta, David Saltmiras, Fiona Sewell, Maria Trainer & Sandrine E Déglin. (2022) Transforming the evaluation of agrochemicals. Pest Management Science 78:12, pages 5049-5056.
Crossref
Crossref
Joel Salazar-Flores, Sarah M. Lomelí-Martínez, Hazael R. Ceja-Gálvez, Juan H. Torres-Jasso, Luis A. Torres-Reyes & Erandis D. Torres-Sánchez. (2022) Impacts of Pesticides on Oral Cavity Health and Ecosystems: A Review. International Journal of Environmental Research and Public Health 19:18, pages 11257.
Crossref
Crossref
Yisheng Wang, Youjin Xiong, Eduardo Alejandro Lozano Garcia, Yiqing Wang & Christopher J. Butch. (2022) Drug Chemical Space as a Guide for New Herbicide Development: A Cheminformatic Analysis. Journal of Agricultural and Food Chemistry 70:31, pages 9625-9636.
Crossref
Crossref
Gina M. Hilton, Catherine Adcock, Gregory Akerman, James Baldassari, Michael Battalora, Warren Casey, Amy J. Clippinger, Rhian Cope, Amber Goetz, A. Wallace Hayes, Sabitha Papineni, Richard C. Peffer, Deborah Ramsingh, Brandy Williamson Riffle, Mitscheli Sanches da Rocha, Natalia Ryan, Edward Scollon, Nicolo Visconti, Douglas C. Wolf, Zhongyu Yan & Anna Lowit. (2022) Rethinking chronic toxicity and carcinogenicity assessment for agrochemicals project (ReCAAP): A reporting framework to support a weight of evidence safety assessment without long-term rodent bioassays. Regulatory Toxicology and Pharmacology 131, pages 105160.
Crossref
Crossref
Kai Wan, Xunyuan Jiang, Xuemei Tang, Lu Xiao, Yan Chen, Congling Huang, Fuwei Zhu, Fuhua Wang & Hanhong Xu. (2022) Study on Absorption, Distribution, Metabolism, and Excretion Properties of Novel Insecticidal GABA Receptor Antagonist, Pyraquinil, in Diamondback Moth Combining MALDI Mass Spectrometry Imaging and High-Resolution Mass Spectrometry. Journal of Agricultural and Food Chemistry 70:20, pages 6072-6083.
Crossref
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Yang Yuan, Yanghuan Zhang, Runzi Zheng, Hongjun Yuan, Ruoyu Zhou, Shuting Jia & Jing Liu. (2022) Elucidating the anti-aging mechanism of Si Jun Zi Tang by integrating network pharmacology and experimental validation in vivo. Aging 14:9, pages 3941-3955.
Crossref
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Tingting Zhang, Wei Wei, Surui Chang, Nanyang Liu & Hao Li. (2022) Integrated Network Pharmacology and Comprehensive Bioinformatics Identifying the Mechanisms and Molecular Targets of Yizhiqingxin Formula for Treatment of Comorbidity With Alzheimer’s Disease and Depression. Frontiers in Pharmacology 13.
Crossref
Crossref
Peter Jeschke. (2022) Manufacturing Approaches of New Halogenated Agrochemicals. European Journal of Organic Chemistry 2022:12.
Crossref
Crossref
Jie Sun, Mei Li, Tingru Lin, Di Wang, Jingyi Chen, Yu Zhang, Qing Mu, Huiting Su, Na Wu, Aiyu Liu, Yimeng Yu, Yulan Liu, Shaojie Wang, Xin Yu, Jingzhu Guo & Weidong Yu. (2022) Cell cycle arrest is an important mechanism of action of compound Kushen injection in the prevention of colorectal cancer. Scientific Reports 12:1.
Crossref
Crossref
Hao Yuan, Xuelian Wu, Xiaomin Wang & Chengfu Yuan. (2022) Chinese herbal decoction astragalus and angelica exerts its therapeutic effect on renal interstitial fibrosis through the inhibition of MAPK, PI3K-Akt and TNF signaling pathways. Genes & Diseases 9:2, pages 510-521.
Crossref
Crossref
Terry Claire & Hays Sean. (2022) Integrating toxicokinetics into toxicology studies and the human health risk assessment process for chemicals: Reduced uncertainty, better health protection. Regulatory Toxicology and Pharmacology 128, pages 105092.
Crossref
Crossref
Gordon C Hard. (2022) Confounders for kidney carcinogenesis in rodent cancer bioassays. Journal of Toxicologic Pathology 35:1, pages 1-6.
Crossref
Crossref
Shujie Xia, Zhangfeng Zhong, Bizhen Gao, Chi Teng Vong, Xuejuan Lin, Jin Cai, Hanlu Gao, Ging Chan & Candong Li. (2021) The important herbal pair for the treatment of COVID-19 and its possible mechanisms. Chinese Medicine 16:1.
Crossref
Crossref
Yu-Mei Tan, Hugh A. Barton, Alan Boobis, Rachel Brunner, Harvey Clewell, Rhian Cope, Jeffrey Dawson, Jeanne Domoradzki, Peter Egeghy, Pankaj Gulati, Brandall Ingle, Nicole Kleinstreuer, Kelly Lowe, Anna Lowit, Elizabeth Mendez, David Miller, Jeffrey Minucci, James Nguyen, Alicia Paini, Monique Perron, Katherine Phillips, Hua Qian, Tharacad Ramanarayanan, Fiona Sewell, Philip Villanueva, John Wambaugh & Michelle Embry. (2021) Opportunities and challenges related to saturation of toxicokinetic processes: Implications for risk assessment. Regulatory Toxicology and Pharmacology 127, pages 105070.
Crossref
Crossref
Arianna Bassan, Vinicius M. Alves, Alexander Amberg, Lennart T. Anger, Scott Auerbach, Lisa Beilke, Andreas Bender, Mark T.D. Cronin, Kevin P. Cross, Jui-Hua Hsieh, Nigel Greene, Raymond Kemper, Marlene T. Kim, Moiz Mumtaz, Tobias Noeske, Manuela Pavan, Julia Pletz, Daniel P. Russo, Yogesh Sabnis, Markus Schaefer, David T. Szabo, Jean-Pierre Valentin, Joerg Wichard, Dominic Williams, David Woolley, Craig Zwickl & Glenn J. Myatt. (2021) In silico approaches in organ toxicity hazard assessment: Current status and future needs in predicting liver toxicity. Computational Toxicology 20, pages 100187.
Crossref
Crossref
Rajeev K. Singla, Pooja Sharma, Ankit Kumar Dubey, Rohit Gundamaraju, Dinesh Kumar, Suresh Kumar, Reecha Madaan, Richa Shri, Christos Tsagkaris, Salvatore Parisi, Shikha Joon, Shailja Singla, Mohammad Amjad Kamal & Bairong Shen. (2021) Natural Product-Based Studies for the Management of Castration-Resistant Prostate Cancer: Computational to Clinical Studies. Frontiers in Pharmacology 12.
Crossref
Crossref
Anne E. Loccisano, Elaine Freeman, Brandy Riffle, Adriana Doi, Markus Frericks, Ivana Fegert & Eric Fabian. (2021) Afidopyropen: Challenges and impact of a toxicokinetic study designed to identify a point of inflection from dose-proportionality. Regulatory Toxicology and Pharmacology 124, pages 104962.
Crossref
Crossref
Satoshi Machino, Yoko Yokoyama, Toyohiro Egawa, Hiroshi Satoh, Katsuhiro Miyajima, Midori Yoshida, Satoshi Asano & Shogo Ozawa. (2021) Case analysis of kinetics investigations in toxicity studies of pesticides to identify the nonlinearity of internal exposure and the influences of nonlinearity on the toxicological interpretation of pesticide residue. Regulatory Toxicology and Pharmacology 124, pages 104958.
Crossref
Crossref
Jie Zhao, Chao Mo, Wei Shi, LiFeng Meng & Jun Ai. (2021) Network Pharmacology Combined with Bioinformatics to Investigate the Mechanisms and Molecular Targets of Astragalus Radix-Panax notoginseng Herb Pair on Treating Diabetic Nephropathy. Evidence-Based Complementary and Alternative Medicine 2021, pages 1-19.
Crossref
Crossref
Xinjia Cai, Heyu Zhang & Tiejun Li. (2021) Multi-target pharmacological mechanisms of Salvia miltiorrhiza against oral submucous fibrosis: A network pharmacology approach. Archives of Oral Biology 126, pages 105131.
Crossref
Crossref
Fangchen Liu, Ling Li, Jian Chen, Ying Wu, Yongbing Cao & Ping Zhong. (2021) A Network Pharmacology to Explore the Mechanism of Calculus Bovis in the Treatment of Ischemic Stroke. BioMed Research International 2021, pages 1-20.
Crossref
Crossref
Peter Jeschke. 2021. Organofluorine Chemistry. Organofluorine Chemistry
363
395
.
Ren-Yu Qu, Jia-Xu Nan, Yao-Chao Yan, Qiong Chen, Ferdinand Ndikuryayo, Xue-Fang Wei, Wen-Chao Yang, Hong-Yan Lin & Guang-Fu Yang. (2021) Structure-Guided Discovery of Silicon-Containing Subnanomolar Inhibitor of Hydroxyphenylpyruvate Dioxygenase as a Potential Herbicide. Journal of Agricultural and Food Chemistry 69:1, pages 459-473.
Crossref
Crossref
Ashley Roberts. 2021. Nutraceuticals. Nutraceuticals
501
518
.
Wout Slob, Marco J Zeilmaker & Rudolf T Hoogenveen. (2020) The Relationship Between Internal and External Dose: Some General Results Based on a Generic Compartmental Model. Toxicological Sciences 177:1, pages 60-70.
Crossref
Crossref
Minne B. Heringa, Nicole H.P. Cnubben, Wout Slob, Marja E.J. Pronk, Andre Muller, Marjolijn Woutersen & Betty C. Hakkert. (2020) Use of the kinetically-derived maximum dose concept in selection of top doses for toxicity studies hampers proper hazard assessment and risk management. Regulatory Toxicology and Pharmacology 114, pages 104659.
Crossref
Crossref
Anne E. Loccisano, James Bus, Bhaskar Gollapudi, Brandy Riffle, Markus Frericks, Ivana Fegert & Eric Fabian. (2020) Use of toxicokinetic data for afidopyropen to determine the dose levels in developmental toxicity studies. Regulatory Toxicology and Pharmacology 113, pages 104644.
Crossref
Crossref
Yanan Song, Haiyan Wang, Yajing Pan & Tonghua Liu. (2019) Investigating the Multi-Target Pharmacological Mechanism of Hedyotis diffusa Willd Acting on Prostate Cancer: A Network Pharmacology Approach. Biomolecules 9:10, pages 591.
Crossref
Crossref
Sajitha Lulu Sudhakaran, Deepa Madathil, Mohanapriya Arumugam & Vino Sundararajan. 2019. Global Virology III: Virology in the 21st Century. Global Virology III: Virology in the 21st Century
117
129
.
Andrew Van Cott, Markus Frericks, Charles Hastings, Naveed Honarvar, Burkhard Flick, Eric Fabian & Bennard van Ravenzwaay. (2018) Uterine adenocarcinoma in the rat induced by afidopyropen. An analysis of the lesion's induction, progression and its relevance to humans. Regulatory Toxicology and Pharmacology 95, pages 29-51.
Crossref
Crossref
J.C. Lamb. 2018. Comprehensive Toxicology. Comprehensive Toxicology
172
182
.
S.A. Saghir & M.A. Dorato. 2018. Comprehensive Toxicology. Comprehensive Toxicology
95
118
.
Fiona Sewell, Manoj Aggarwal, Gerald Bachler, Alan Broadmeadow, Nichola Gellatly, Emma Moore, Sally Robinson, Martijn Rooseboom, Alexander Stevens, Claire Terry & Natalie Burden. (2017) The current status of exposure-driven approaches for chemical safety assessment: A cross-sector perspective. Toxicology 389, pages 109-117.
Crossref
Crossref
Peter Jeschke. (2017) Latest generation of halogen-containing pesticides. Pest Management Science 73:6, pages 1053-1066.
Crossref
Crossref
Susan J. Borghoff, Caroline Ring, Marcy I. Banton & Teresa L. Leavens. (2017)
Physiologically based pharmacokinetic model for ethyl
tertiary
-butyl ether and
tertiary
-butyl alcohol in rats: Contribution of binding to α2u-globulin in male rats and high-exposure nonlinear kinetics to toxicity and cancer outcomes
. Journal of Applied Toxicology 37:5, pages 621-640.
Crossref
Crossref
Sheelendra Pratap Singh, Nistha Dwivedi, Kanumuri Siva Rama Raju, Isha Taneja & Mohammad Wahajuddin. (2016) Validation of a Rapid and Sensitive UPLC–MS-MS Method Coupled with Protein Precipitation for the Simultaneous Determination of Seven Pyrethroids in 100 µL of Rat Plasma by Using Ammonium Adduct as Precursor Ion. Journal of Analytical Toxicology 40:3, pages 213-221.
Crossref
Crossref
Claire Terry, Sean Hays, Alene T. McCoy, Lisa G. McFadden, Manoj Aggarwal, Reza J. Rasoulpour & Daland R. Juberg. (2016) Implementing a framework for integrating toxicokinetics into human health risk assessment for agrochemicals. Regulatory Toxicology and Pharmacology 75, pages 89-104.
Crossref
Crossref
Peter Jeschke. (2016) Propesticides and their use as agrochemicals. Pest Management Science 72:2, pages 210-225.
Crossref
Crossref
Ashley Roberts. 2016. Nutraceuticals. Nutraceuticals
417
434
.
Kamin J. Johnson, Bethany R. Hannas, Sue Marty, Carol L. Zablotny, Jessica LaRocca, Nicholas Ball & Amanda K. Andrus. 2017. Developmental and Reproductive Toxicology. Developmental and Reproductive Toxicology
117
183
.
Virginie Ducrot, Roman Ashauer, Agnieszka J Bednarska, Silvia Hinarejos, Pernille Thorbek & Gabriel Weyman. (2016) Using toxicokinetic-toxicodynamic modeling as an acute risk assessment refinement approach in vertebrate ecological risk assessment. Integrated Environmental Assessment and Management 12:1, pages 32-45.
Crossref
Crossref
Ayako Takei. (2015) ILSI Health and Environmental Sciences Institute (HESI), global leader in advancing translational science to create science-based solutions for a sustainable, healthier world. Genes and Environment 37:1.
Crossref
Crossref
Esther F.A. Brandon, Petra C.E. van Kesteren, Jan C.H. van Eijkeren, Marc Tienstra, Patricia Lopez Sanchez, Elisa C.M. Tonk, Aldert H. Piersma & Peter M.J. Bos. (2015) Implementation of toxicokinetics in toxicity studies – Toxicokinetics of 4-methylanisole and its metabolites in juvenile and adult rats. Regulatory Toxicology and Pharmacology 73:1, pages 55-64.
Crossref
Crossref
Yuri Dancik, John A. Troutman & Joanna Jaworska. (2015) Estimation of in vivo dose of dermally applied chemicals leading to estrogen/androgen receptor-mediated toxicity from in vitro data—Illustration with four reproductive toxicants. Reproductive Toxicology 55, pages 50-63.
Crossref
Crossref
Shakil Ahmed Saghir. (2015) Rethinking guideline toxicity testing. Regulatory Toxicology and Pharmacology 72:2, pages 423-428.
Crossref
Crossref
Thomas H. Hutchinson, Judith C. Madden, Vinny Naidoo & Colin H. Walker. (2014) Comparative metabolism as a key driver of wildlife species sensitivity to human and veterinary pharmaceuticals. Philosophical Transactions of the Royal Society B: Biological Sciences 369:1656, pages 20130583.
Crossref
Crossref
Chun Liu, Agnieszka J. Bednarska, Richard M. Sibly, Roger C. Murfitt, Peter Edwards & Pernille Thorbek. (2014) Incorporating toxicokinetics into an individual-based model for more realistic pesticide exposure estimates: A case study of the wood mouse. Ecological Modelling 280, pages 30-39.
Crossref
Crossref
Mary Sue Marty, Barbara H. Neal, Carol L. Zablotny, Barry L. Yano, Amanda K. Andrus, Michael R. Woolhiser, Darrell R. Boverhof, Shakil A. Saghir, Adam W. Perala, Julie K. Passage, Marie A. Lawson, James S. Bus, James C. LambIVIV & Larry Hammond. (2013) An F1-Extended One-Generation Reproductive Toxicity Study in Crl:CD(SD) Rats With 2,4-Dichlorophenoxyacetic Acid. Toxicological Sciences 136:2, pages 527-547.
Crossref
Crossref
Shakil A. Saghir, Mary S. Marty, Carol L. Zablotny, Julie K. Passage, Adam W. Perala, Barbara H. Neal, Larry Hammond & James S. Bus. (2013) Life-Stage-, Sex-, and Dose-Dependent Dietary Toxicokinetics and Relationship to Toxicity of 2,4-Dichlorophenoxyacetic Acid (2,4-D) in Rats: Implications for Toxicity Test Dose Selection, Design, and Interpretation. Toxicological Sciences 136:2, pages 294-307.
Crossref
Crossref
Jos G.M. Bessems & Liesbeth Geraets. (2013) Proper knowledge on toxicokinetics improves human hazard testing and subsequent health risk characterisation. A case study approach. Regulatory Toxicology and Pharmacology 67:3, pages 325-334.
Crossref
Crossref
Kathryn L. Chapman, Henry Holzgrefe, Lauren E. Black, Marilyn Brown, Gary Chellman, Christine Copeman, Jessica Couch, Stuart Creton, Sean Gehen, Alan Hoberman, Lewis B. Kinter, Stephen Madden, Charles Mattis, Hugh A. Stemple & Stephen Wilson. (2013) Pharmaceutical toxicology: Designing studies to reduce animal use, while maximizing human translation. Regulatory Toxicology and Pharmacology 66:1, pages 88-103.
Crossref
Crossref
Katherine Coady, Troy Marino, Johnson Thomas, Lindsay Sosinski, Barbara Neal & Larry Hammond. (2013) An evaluation of 2,4-dichlorophenoxyacetic acid in the Amphibian Metamorphosis Assay and the Fish Short-Term Reproduction Assay. Ecotoxicology and Environmental Safety 90, pages 143-150.
Crossref
Crossref
Agnieszka J. Bednarska, Peter Edwards, Richard Sibly & Pernille Thorbek. (2013) A toxicokinetic model for thiamethoxam in rats: implications for higher-tier risk assessment. Ecotoxicology 22:3, pages 548-557.
Crossref
Crossref
Haifang Wang, Sheng-Tao Yang, Aoneng Cao & Yuanfang Liu. (2012)
Quantification of Carbon Nanomaterials
in Vivo
. Accounts of Chemical Research 46:3, pages 750-760.
Crossref
Crossref
I. Fegert, R. Billington, P. Botham, E. Carney, R.E. FitzGerald, T. Hanley, R. Lewis, M.S. Marty, S. Schneider, L.P. Sheets, B. Stahl & B. van Ravenzwaay. (2012) Feasibility of the extended one-generation reproductive toxicity study (OECD 443). Reproductive Toxicology 34:3, pages 331-339.
Crossref
Crossref
Lisa G. McFadden, Michael J. Bartels, David L. Rick, Paul S. Price, Donald D. Fontaine & Shakil A. Saghir. (2012) Statistical methodology to determine kinetically derived maximum tolerated dose in repeat dose toxicity studies. Regulatory Toxicology and Pharmacology 63:2, pages 344-351.
Crossref
Crossref
Shakil A. Saghir, Michael J. Bartels, David L. Rick, Alene T. McCoy, Reza J. Rasoulpour, Robert G. Ellis-Hutchings, M. Sue Marty, Claire Terry, Jason P. Bailey, Richard Billington & James S. Bus. (2012) Assessment of diurnal systemic dose of agrochemicals in regulatory toxicity testing – An integrated approach without additional animal use. Regulatory Toxicology and Pharmacology 63:2, pages 321-332.
Crossref
Crossref
John L. Butenhoff, James A. Bjork, Shu-Ching Chang, David J. Ehresman, George A. Parker, Kaberi Das, Christopher Lau, Paul H. Lieder, François M. van Otterdijk & Kendall B. Wallace. (2012) Toxicological evaluation of ammonium perfluorobutyrate in rats: Twenty-eight-day and ninety-day oral gavage studies. Reproductive Toxicology 33:4, pages 513-530.
Crossref
Crossref
Stuart Creton, Shakil A. Saghir, Michael J. Bartels, Richard Billington, James S. Bus, Will Davies, Matthew P. Dent, Gabrielle M. Hawksworth, Simon Parry & Kim Z. Travis. (2012) Use of toxicokinetics to support chemical evaluation: Informing high dose selection and study interpretation. Regulatory Toxicology and Pharmacology 62:2, pages 241-247.
Crossref
Crossref
Susan L. Makris. 2012. Pediatric Nonclinical Drug Testing. Pediatric Nonclinical Drug Testing
93
113
.
Richard A. Becker, Sean M. Hays, Steven Robison & Lesa L. Aylward. (2012) Development of Screening Tools for the Interpretation of Chemical Biomonitoring Data. Journal of Toxicology 2012, pages 1-10.
Crossref
Crossref
Ronald D. HoodSusan L. Makris. 2011. Developmental and Reproductive Toxicology: A Practical Approach. Developmental and Reproductive Toxicology: A Practical Approach
675
707
.
Lesa L. Aylward, Richard A. Becker, Christopher R. Kirman & Sean M. Hays. (2011) Assessment of margin of exposure based on biomarkers in blood: An exploratory analysis. Regulatory Toxicology and Pharmacology 61:1, pages 44-52.
Crossref
Crossref
Joachim D Pleil, Matthew A Stiegel, Jon R Sobus, Qian Liu & Michael C Madden. (2011) Observing the human exposome as reflected in breath biomarkers: heat map data interpretation for environmental and intelligence research. Journal of Breath Research 5:3, pages 037104.
Crossref
Crossref
Jürgen Angerer, Lesa L. Aylward, Sean M. Hays, Birger Heinzow & Michael Wilhelm. (2011) Human biomonitoring assessment values: Approaches and data requirements. International Journal of Hygiene and Environmental Health 214:5, pages 348-360.
Crossref
Crossref
A.W. Hayes, A.D. Dayan, W.C. Hall, R.L. Kodell, G.M. Williams, W.D. Waddell, R.S. Slesinski & C.L. Kruger. (2011) A review of mammalian carcinogenicity study design and potential effects of alternate test procedures on the safety evaluation of food ingredients. Regulatory Toxicology and Pharmacology 60:1, pages S1-S34.
Crossref
Crossref
Sarah Adler, David Basketter, Stuart Creton, Olavi Pelkonen, Jan van Benthem, Valérie Zuang, Klaus Ejner Andersen, Alexandre Angers-Loustau, Aynur Aptula, Anna Bal-Price, Emilio Benfenati, Ulrike Bernauer, Jos Bessems, Frederic Y. Bois, Alan Boobis, Esther Brandon, Susanne Bremer, Thomas Broschard, Silvia Casati, Sandra Coecke, Raffaella Corvi, Mark Cronin, George Daston, Wolfgang Dekant, Susan Felter, Elise Grignard, Ursula Gundert-Remy, Tuula Heinonen, Ian Kimber, Jos Kleinjans, Hannu Komulainen, Reinhard Kreiling, Joachim Kreysa, Sofia Batista Leite, George Loizou, Gavin Maxwell, Paolo Mazzatorta, Sharon Munn, Stefan Pfuhler, Pascal Phrakonkham, Aldert Piersma, Albrecht Poth, Pilar Prieto, Guillermo Repetto, Vera Rogiers, Greet Schoeters, Michael Schwarz, Rositsa Serafimova, Hanna Tähti, Emanuela Testai, Joost van Delft, Henk van Loveren, Mathieu Vinken, Andrew Worth & José-Manuel Zaldivar. (2011) Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010. Archives of Toxicology 85:5, pages 367-485.
Crossref
Crossref
K. Schroeder, K.D. Bremm, N. Alépée, J.G.M. Bessems, B. Blaauboer, S.N. Boehn, C. Burek, S. Coecke, L. Gombau, N.J. Hewitt, J. Heylings, J. Huwyler, M. Jaeger, M. Jagelavicius, N. Jarrett, H. Ketelslegers, I. Kocina, J. Koester, J. Kreysa, R. Note, A. Poth, M. Radtke, V. Rogiers, J. Scheel, T. Schulz, H. Steinkellner, M. Toeroek, M. Whelan, P. Winkler & W. Diembeck. (2011) Report from the EPAA workshop: In vitro ADME in safety testing used by EPAA industry sectors. Toxicology in Vitro 25:3, pages 589-604.
Crossref
Crossref
Susan L. Makris & Scott Glaberman. 2011. Reproductive and Developmental Toxicology. Reproductive and Developmental Toxicology
219
225
.
Laura M. Plunkett, A. Michael Kaplan & Richard A. Becker. (2010) An enhanced tiered toxicity testing framework with triggers for assessing hazards and risks of commodity chemicals. Regulatory Toxicology and Pharmacology 58:3, pages 382-394.
Crossref
Crossref
Kathleen C. Raffaele, Jess Rowland, Brenda May, Susan L. Makris, Kelly Schumacher & Louis J. Scarano. (2010) The use of developmental neurotoxicity data in pesticide risk assessments. Neurotoxicology and Teratology 32:5, pages 563-572.
Crossref
Crossref
J.D. Pleil, M.A. Stiegel, J.R. Sobus, S. Tabucchi, A.J. Ghio & M.C. Madden. (2010) Cumulative exposure assessment for trace-level polycyclic aromatic hydrocarbons (PAHs) using human blood and plasma analysis. Journal of Chromatography B 878:21, pages 1753-1760.
Crossref
Crossref
Philip Martin, Robert Riley, Paul Thompson, Dominic Williams, David Back & Andrew Owen. (2010) Effect of prototypical inducers on ligand activated nuclear receptor regulated drug disposition genes in rodent hepatic and intestinal cells. Acta Pharmacologica Sinica 31:1, pages 51-65.
Crossref
Crossref
Anthony M. Holmes, Stuart Creton & Kathryn Chapman. (2010) Working in partnership to advance the 3Rs in toxicity testing. Toxicology 267:1-3, pages 14-19.
Crossref
Crossref
R.L. Cooper & N.G. Doerrer. 2010. Comprehensive Toxicology. Comprehensive Toxicology
159
172
.
Stuart Creton, Richard Billington, Will Davies, Matthew P. Dent, Gabrielle M. Hawksworth, Simon Parry & Kim Z. Travis. (2009) Application of toxicokinetics to improve chemical risk assessment: Implications for the use of animals. Regulatory Toxicology and Pharmacology 55:3, pages 291-299.
Crossref
Crossref
Ashley Roberts & Andrew G. Renwick. 2009. General, Applied and Systems Toxicology. General, Applied and Systems Toxicology.
Ralph L. Cooper. (2009) Current developments in reproductive toxicity testing of pesticides. Reproductive Toxicology 28:2, pages 180-187.
Crossref
Crossref
Stuart Creton, Richard Billington, Will Davies, Matthew P. Dent, Gabrielle M. Hawksworth, Simon Parry & Kim Z. Travis. (2009) Improved risk assessment of chemicals through the application of toxicokinetic information: Opportunities for the replacement, reduction and refinement of animal use. Toxicology 262:1, pages 10-11.
Crossref
Crossref
Richard JudsonAnn RichardDavid J. DixKeith HouckMatthew MartinRobert KavlockVicki DellarcoTala Henry, Todd Holderman, Philip Sayre, Shirlee TanThomas CarpenterEdwin Smith. (2009) The Toxicity Data Landscape for Environmental Chemicals. Environmental Health Perspectives 117:5, pages 685-695.
Crossref
Crossref
Sean M. Hays & Lesa L. Aylward. (2008) Using Biomonitoring Equivalents to interpret human biomonitoring data in a public health risk context. Journal of Applied Toxicology 29:4, pages 275-288.
Crossref
Crossref
Allan S. Felsot. 2009. Information Resources in Toxicology. Information Resources in Toxicology
151
165
.
Robert Combes, Christina Grindon, Mark T.D. Cronin, David W. Roberts & John F. Garrod. (2008) Integrated Decision-tree Testing Strategies for Acute Systemic Toxicity and Toxicokinetics with Respect to the Requirements of the EU REACH Legislation. Alternatives to Laboratory Animals 36:1_suppl, pages 91-109.
Crossref
Crossref
Sean M. Hays, Lesa L. Aylward, Judy S. LaKind, Michael J. Bartels, Hugh A. Barton, Peter J. Boogaard, Conrad Brunk, Stephen DiZio, Michael Dourson, Daniel A. Goldstein, John Lipscomb, Michael E. Kilpatrick, Daniel Krewski, Kannan Krishnan, Monica Nordberg, Miles Okino, Yu-Mei Tan, Claude Viau & Janice W. Yager. (2008) Guidelines for the derivation of Biomonitoring Equivalents: Report from the Biomonitoring Equivalents Expert Workshop. Regulatory Toxicology and Pharmacology 51:3, pages S4-S15.
Crossref
Crossref
Miyoung Yoon & Hugh A. Barton. (2008) Predicting Maternal Rat and Pup Exposures: How Different are They?. Toxicological Sciences 102:1, pages 15-32.
Crossref
Crossref
Robert Combes, Christina Grindon, Mark T.D. Cronin, David W. Roberts & John F. Garrod. (2008) Integrated Decision-tree Testing Strategies for Acute Systemic Toxicity and Toxicokinetics with Respect to the Requirements of the EU REACH Legislation. Alternatives to Laboratory Animals 36:1, pages 45-63.
Crossref
Crossref
D. J. MacLachlan & R. Bhula. (2008) Estimating the residue transfer of pesticides in animal feedstuffs to livestock tissues, milk and eggs: a review. Australian Journal of Experimental Agriculture 48:5, pages 589.
Crossref
Crossref
. 2007. Genomics in Regulatory Ecotoxicology. Genomics in Regulatory Ecotoxicology
91
114
.
. (2007) Opinion of the Scientific Panel PPR related to the revision of Annexes II and III to Council Directive 91/414/EEC concerning the placing of plant protection products on the market - Toxicological and metabolism studies. EFSA Journal 5:2, pages 449.
Crossref
Crossref
T.G. Vermeire, A.J. Baars, J.G.M. Bessems, B.J. Blaauboer, W. Slob & J.J.A. Muller. 2007. Risk Assessment of Chemicals. Risk Assessment of Chemicals
227
280
.