Citations (185)
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Nora Astrain-Redin, Niccolò Paoletti, Daniel Plano, Alessandro Bonardi, Paola Gratteri, Andrea Angeli, Carmen Sanmartin & Claudiu T. Supuran. (2023) Selenium-analogs based on natural sources as cancer-associated carbonic anhydrase isoforms IX and XII inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1.
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Francesco Fiorentino, Alessio Nocentini, Dante Rotili, Claudiu T. Supuran & Antonello Mai. (2023) Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1.
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Morteza Abdoli, Claudiu T. Supuran & Raivis Žalubovskis. (2023) 2-((1H-Benzo[d]imidazol-2-yl)amino)benzo[d]thiazole-6-sulphonamides: a class of carbonic anhydrase II and VII-selective inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1.
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Ashok Aspatwar, Alessandro Bonardi, Heidi Aisala, Ksenia Zueva, Craig R Primmer, Jaakko Lumme, Seppo Parkkila & Claudiu T. Supuran. (2023) Sulphonamide inhibition studies of the β-carbonic anhydrase GsaCAβ present in the salmon platyhelminth parasite Gyrodactylus salaris. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1.
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Andrea Angeli & Claudiu T. Supuran. (2023) Click chemistry approaches for developing carbonic anhydrase inhibitors and their applications. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1.
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Morteza Abdoli, Alessandro Bonardi, Claudiu T. Supuran & Raivis Žalubovskis. (2023) 4-Cyanamidobenzenesulfonamide derivatives: a novel class of human and bacterial carbonic anhydrase inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1, pages 156-165.
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Amina Merabti, Sébastien Richeter, Claudiu T. Supuran, Sébastien Clement & Jean-Yves Winum. (2023) Are tumour-associated carbonic anhydrases genuine therapeutic targets for photodynamic therapy?. Expert Opinion on Therapeutic Targets 0:0, pages 1-10.
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Varun Chahal & Rita Kakkar. (2023) A combination strategy of structure-based virtual screening, MM-GBSA, cross docking, molecular dynamics and metadynamics simulations used to investigate natural compounds as potent and specific inhibitors of tumor linked human carbonic anhydrase IX. Journal of Biomolecular Structure and Dynamics 41:12, pages 5465-5480.
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Claudiu T Supuran. (2023) Targeting carbonic anhydrases for the management of hypoxic metastatic tumors. Expert Opinion on Therapeutic Patents 0:0, pages 1-20.
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Xiaojuan Wang, Deyin Zhang, Weiming Wang, Feng Lv, Xin Pang, Guohua Liu, Fadi Li & Xiaoxue Zhang. (2023) Transcriptome profiling reveals differential gene expression in the rumen of Hu lambs at different developmental stages. Animal Biotechnology 34:3, pages 471-481.
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Andrea Angeli, Linda J Urbański, Clemente Capasso, Seppo Parkkila & Claudiu T. Supuran. (2022) Activation studies with amino acids and amines of a β-carbonic anhydrase from Mammaliicoccus (Staphylococcus) sciuri previously annotated as Staphylococcus aureus (SauBCA) carbonic anhydrase. Journal of Enzyme Inhibition and Medicinal Chemistry 37:1, pages 2786-2792.
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Ashok Aspatwar, Harlan Barker, Heidi Aisala, Ksenia Zueva, Marianne Kuuslahti, Martti Tolvanen, Craig R. Primmer, Jaakko Lumme, Alessandro Bonardi, Amit Tripathi, Seppo Parkkila & Claudiu T. Supuran. (2022) Cloning, purification, kinetic and anion inhibition studies of a recombinant β-carbonic anhydrase from the Atlantic salmon parasite platyhelminth Gyrodactylus salaris. Journal of Enzyme Inhibition and Medicinal Chemistry 37:1, pages 1577-1586.
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Mateusz Kciuk, Adrianna Gielecińska, Somdutt Mujwar, Mariusz Mojzych, Beata Marciniak, Rafał Drozda & Renata Kontek. (2022) Targeting carbonic anhydrase IX and XII isoforms with small molecule inhibitors and monoclonal antibodies. Journal of Enzyme Inhibition and Medicinal Chemistry 37:1, pages 1278-1298.
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Mona F. Said, Riham F. George, Andrea Petreni, Claudiu T. Supuran & Nada M. Mohamed. (2022) Synthesis, molecular modelling and QSAR study of new N-phenylacetamide-2-oxoindole benzensulfonamide conjugates as carbonic anhydrase inhibitors with antiproliferative activity. Journal of Enzyme Inhibition and Medicinal Chemistry 37:1, pages 701-717.
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Wagdy M. Eldehna, Mohammed S. Taghour, Tarfah Al-Warhi, Alessio Nocentini, Mostafa M. Elbadawi, Hazem A. Mahdy, Mohamed A. Abdelrahman, Ohoud J. Alotaibi, Nada Aljaeed, Diaaeldin M. Elimam, Kamyar Afarinkia, Hatem A. Abdel-Aziz & Claudiu T. Supuran. (2022) Discovery of 2,4-thiazolidinedione-tethered coumarins as novel selective inhibitors for carbonic anhydrase IX and XII isoforms. Journal of Enzyme Inhibition and Medicinal Chemistry 37:1, pages 531-541.
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Muhammad Umair Amin, Sajid Ali, Muhammad Yasir Ali, Dominik C. Fuhrmann, Imran Tariq, Benjamin S. Seitz, Eduard Preis, Jana Brüßler, Bernhard Brüne & Udo Bakowsky. (2022) Co-delivery of carbonic anhydrase IX inhibitor and doxorubicin as a promising approach to address hypoxia-induced chemoresistance. Drug Delivery 29:1, pages 2072-2085.
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Amarjyoti Das Mahapatra, Aarfa Queen, Mohd Yousuf, Parvez Khan, Afzal Hussain, Md. Tabish Rehman, Mohamed F. Alajmi, Bhaskar Datta & Md. Imtaiyaz Hassan. (2022) Design and development of 5-(4H)-oxazolones as potential inhibitors of human carbonic anhydrase VA: towards therapeutic management of diabetes and obesity. Journal of Biomolecular Structure and Dynamics 40:7, pages 3144-3154.
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Claudiu T. Supuran. (2021) Carbonic anhydrase inhibitors: an update on experimental agents for the treatment and imaging of hypoxic tumors. Expert Opinion on Investigational Drugs 30:12, pages 1197-1208.
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Francesco Mincione, Alessio Nocentini & Claudiu T. Supuran. (2021) Advances in the discovery of novel agents for the treatment of glaucoma. Expert Opinion on Drug Discovery 16:10, pages 1209-1225.
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Anne E.G. Lenferink, Paul C. McDonald, Christiane Cantin, Suzanne Grothé, Mylene Gosselin, Jason Baardsnes, Myriam Banville, Paul Lachance, Alma Robert, Yuneivy Cepero-Donates, Stevo Radinovic, Patrick Salois, Marie Parat, Hafida Oamari, Annie Dulude, Mehul Patel, Martin Lafrance, Andrea Acel, Nathalie Bousquet-Gagnon, Denis L’Abbé, Alex Pelletier, Félix Malenfant, Maria Jaramillo, Maureen O’Connor-Mccourt, Cunle Wu, Yves Durocher, Mélanie Duchesne, Christine Gadoury, Anne Marcil, Yves Fortin, Beatrice Paul-Roc, Maurizio Acchione, Shawn C. Chafe, Oksana Nemirovsky, Joseph Lau, Francois Bénard & Shoukat Dedhar. (2021) Isolation and characterization of monoclonal antibodies against human carbonic anhydrase-IX. mAbs 13:1.
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Livio Racané, Valentina Rep, Sandra Kraljević Pavelić, Petra Grbčić, Iva Zonjić, Marijana Radić Stojković, Martin C. Taylor, John M. Kelly & Silvana Raić-Malić. (2021) Synthesis, antiproliferative and antitrypanosomal activities, and DNA binding of novel 6-amidino-2-arylbenzothiazoles. Journal of Enzyme Inhibition and Medicinal Chemistry 36:1, pages 1952-1967.
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Claudiu T. Supuran. (2021) Multitargeting approaches involving carbonic anhydrase inhibitors: hybrid drugs against a variety of disorders. Journal of Enzyme Inhibition and Medicinal Chemistry 36:1, pages 1702-1714.
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Chandra Bhushan Mishra, Raj Kumar Mongre, Amresh Prakash, Raok Jeon, Claudiu T. Supuran & Myeong-Sok Lee. (2021) Anti-breast cancer action of carbonic anhydrase IX inhibitor 4-[4-(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1-yl)-benzylidene-hydrazinocarbonyl]-benzenesulfonamide (BSM-0004): in vitro and in vivo studies. Journal of Enzyme Inhibition and Medicinal Chemistry 36:1, pages 954-963.
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Gustavo Provensi, Alessio Nocentini, Maria Beatrice Passani, Patrizio Blandina & Claudiu T. Supuran. (2021) Activation of carbonic anhydrase isoforms involved in modulation of emotional memory and cognitive disorders with histamine agonists, antagonists and derivatives. Journal of Enzyme Inhibition and Medicinal Chemistry 36:1, pages 719-726.
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Heping Zhu, Shilong Ying, Bingluo Zhou, Xinyang Hu, Xiao Liang, Wangyu Li, Dungai Wang, Hongchuan Jin & Yuanjiang Pan. (2021) Design, synthesis, and evaluation of novel coumarin-dithiocarbamate derivatives (IDs) as anti-colorectal cancer agents. Journal of Enzyme Inhibition and Medicinal Chemistry 36:1, pages 593-604.
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Claudiu T Supuran. (2020) Experimental Carbonic Anhydrase Inhibitors for the Treatment of Hypoxic Tumors. Journal of Experimental Pharmacology 12, pages 603-617.
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Yanjie Hu, Jisong Zhang, Huihui Hu, Shan Xu, Li Xu & Enguo Chen. (2020) Gefitinib encapsulation based on nano-liposomes for enhancing the curative effect of lung cancer. Cell Cycle 19:24, pages 3581-3594.
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Claudiu T. Supuran. (2020) Exploring the multiple binding modes of inhibitors to carbonic anhydrases for novel drug discovery. Expert Opinion on Drug Discovery 15:6, pages 671-686.
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Claudiu T. Supuran. (2020) An update on drug interaction considerations in the therapeutic use of carbonic anhydrase inhibitors. Expert Opinion on Drug Metabolism & Toxicology 16:4, pages 297-307.
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Claudiu T. Supuran. (2020) Coumarin carbonic anhydrase inhibitors from natural sources. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 1462-1470.
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Bilal A. Al-Jaidi, Pran Kishore Deb, Soha Taher Telfah, Abdel Naser Dakkah, Yazan A. Bataineh, Qutaiba Ahmed Al Khames Aga, Mohammad A. Al-dhoun, Ala’ Ali Ahmad Al-Subeihi, Haifa’a Marouf Odetallah, Sanaa K. Bardaweel, Raghuprasad Mailavaram, Katharigatta N. Venugopala & Anroop B. Nair. (2020) Synthesis and evaluation of 2,4,5-trisubstitutedthiazoles as carbonic anhydrase-III inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 1483-1490.
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Alejandro I. Lorenzo-Pouso, Mercedes Gallas-Torreira, Mario Pérez-Sayáns, Cintia M. Chamorro-Petronacci, Oscar Alvarez-Calderon, Bahi Takkouche, Claudiu T. Supuran & Abel García-García. (2020) Prognostic value of CAIX expression in oral squamous cell carcinoma: a systematic review and meta-analysis. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 1258-1266.
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Patrizio Blandina, Gustavo Provensi, Maria Beatrice Passani, Clemente Capasso & Claudiu T. Supuran. (2020) Carbonic anhydrase modulation of emotional memory. Implications for the treatment of cognitive disorders. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 1206-1214.
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Mehmet Oguz, Erbay Kalay, Suleyman Akocak, Alessio Nocentini, Nebih Lolak, Mehmet Boga, Mustafa Yilmaz & Claudiu T. Supuran. (2020) Synthesis of calix[4]azacrown substituted sulphonamides with antioxidant, acetylcholinesterase, butyrylcholinesterase, tyrosinase and carbonic anhydrase inhibitory action. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 1215-1223.
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Silvia Peppicelli, Elena Andreucci, Jessica Ruzzolini, Francesca Bianchini, Chiara Nediani, Claudiu T. Supuran & Lido Calorini. (2020) The Carbonic Anhydrase IX inhibitor SLC-0111 as emerging agent against the mesenchymal stem cell-derived pro-survival effects on melanoma cells. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 1185-1193.
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Aleksandrs Pustenko, Alessio Nocentini, Paola Gratteri, Alessandro Bonardi, Igor Vozny, Raivis Žalubovskis & Claudiu T. Supuran. (2020) The antibiotic furagin and its derivatives are isoform-selective human carbonic anhydrase inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 1011-1020.
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Hasan Küçükbay, Zeynep Gönül, F. Zehra Küçükbay, Andrea Angeli, Gianluca Bartolucci & Claudiu T. Supuran. (2020) Preparation, carbonic anhydrase enzyme inhibition and antioxidant activity of novel 7-amino-3,4-dihydroquinolin-2(1H)-one derivatives incorporating mono or dipeptide moiety. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 1021-1026.
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Mustafa Durgun, Cüneyt Türkeş, Mesut Işık, Yeliz Demir, Ali Saklı, Ali Kuru, Abdussamat Güzel, Şükrü Beydemir, Suleyman Akocak, Sameh M. Osman, Zeid AlOthman & Claudiu T. Supuran. (2020) Synthesis, characterisation, biological evaluation and in silico studies of sulphonamide Schiff bases. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 950-962.
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Jeremie Brichet, Rodrigo Arancibia, Emanuela Berrino & Claudiu T. Supuran. (2020) Bioorganometallic derivatives of 4-hydrazino-benzenesulphonamide as carbonic anhydrase inhibitors: synthesis, characterisation and biological evaluation. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 622-628.
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Aleksandrs Pustenko, Alessio Nocentini, Anastasija Balašova, Mikhail Krasavin, Raivis Žalubovskis & Claudiu T. Supuran. (2020) 7-Acylamino-3H-1,2-benzoxathiepine 2,2-dioxides as new isoform-selective carbonic anhydrase IX and XII inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 650-656.
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Rakia Abd Alhameed, Emanuela Berrino, Zainab Almarhoon, Ayman El-Faham & Claudiu T. Supuran. (2020) A class of carbonic anhydrase IX/XII – selective carboxylate inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 549-554.
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Hasan Küçükbay, Nesrin Buğday, F. Zehra Küçükbay, Andrea Ageli, Gianluca Bartolucci & Claudiu T. Supuran. (2020) Synthesis and human carbonic anhydrase I, II, VA, and XII inhibition with novel amino acid–sulphonamide conjugates. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 489-497.
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Nabih Lolak, Mehmet Boga, Muhammed Tuneg, Gulcin Karakoc, Suleyman Akocak & Claudiu T. Supuran. (2020) Sulphonamides incorporating 1,3,5-triazine structural motifs show antioxidant, acetylcholinesterase, butyrylcholinesterase, and tyrosinase inhibitory profile. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 424-431.
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Jessica Ruzzolini, Anna Laurenzana, Elena Andreucci, Silvia Peppicelli, Francesca Bianchini, Fabrizio Carta, Claudiu T. Supuran, Maria Novella Romanelli, Chiara Nediani & Lido Calorini. (2020) A potentiated cooperation of carbonic anhydrase IX and histone deacetylase inhibitors against cancer. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 391-397.
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Giulio Poli, Salvatore Galati, Adriano Martinelli, Claudiu T. Supuran & Tiziano Tuccinardi. (2020) Development of a cheminformatics platform for selectivity analyses of carbonic anhydrase inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 365-371.
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Sinan Bilginer, Baris Gonder, Halise Inci Gul, Ruya Kaya, Ilhami Gulcin, Baris Anil & Claudiu T. Supuran. (2020) Novel sulphonamides incorporating triazene moieties show powerful carbonic anhydrase I and II inhibitory properties. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 325-329.
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Ali Irfan, Fozia Batool, Syeda Andleeb Zahra Naqvi, Amjad Islam, Sameh M. Osman, Alessio Nocentini, Siham A. Alissa & Claudiu T. Supuran. (2020) Benzothiazole derivatives as anticancer agents. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 265-279.
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Ozen Ozensoy Guler, Claudiu. T. Supuran & Clemente Capasso. (2020) Carbonic anhydrase IX as a novel candidate in liquid biopsy. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 255-260.
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Mohamed A. Abdelrahman, Wagdy M. Eldehna, Alessio Nocentini, Hany S. Ibrahim, Hadia Almahli, Hatem A. Abdel-Aziz, Sahar M. Abou-Seri & Claudiu T. Supuran. (2020) Novel benzofuran-based sulphonamides as selective carbonic anhydrases IX and XII inhibitors: synthesis and in vitro biological evaluation. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 298-305.
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Aleksandrs Pustenko, Alessio Nocentini, Anastasija Balašova, Ahmed Alafeefy, Mikhail Krasavin, Raivis Žalubovskis & Claudiu T. Supuran. (2020) Aryl derivatives of 3H-1,2-benzoxathiepine 2,2-dioxide as carbonic anhydrase inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 245-254.
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Manuel A. Llanos, María L. Sbaraglini, María L. Villalba, María D. Ruiz, Carolina Carrillo, Catalina Alba Soto, Alan Talevi, Andrea Angeli, Seppo Parkkila, Claudiu T. Supuran & Luciana Gavernet. (2020) A structure-based approach towards the identification of novel antichagasic compounds: Trypanosoma cruzi carbonic anhydrase inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 21-30.
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Alessio Nocentini & Claudiu T. Supuran. (2019) Advances in the structural annotation of human carbonic anhydrases and impact on future drug discovery. Expert Opinion on Drug Discovery 14:11, pages 1175-1197.
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Claudiu T. Supuran. (2019) Agents for the prevention and treatment of age-related macular degeneration and macular edema: a literature and patent review. Expert Opinion on Therapeutic Patents 29:10, pages 761-767.
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Ciro Milite, Giorgio Amendola, Alessio Nocentini, Silvia Bua, Alessandra Cipriano, Elisabetta Barresi, Alessandra Feoli, Ettore Novellino, Federico Da Settimo, Claudiu T. Supuran, Sabrina Castellano, Sandro Cosconati & Sabrina Taliani. (2019) Novel 2-substituted-benzimidazole-6-sulfonamides as carbonic anhydrase inhibitors: synthesis, biological evaluation against isoforms I, II, IX and XII and molecular docking studies. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 1697-1710.
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Mohammad M. Al-Sanea, Ahmed Elkamhawy, Sora Paik, Silvia Bua, So Ha Lee, Mohamed A. Abdelgawad, Eun Joo Roh, Wagdy M. Eldehna & Claudiu T. Supuran. (2019) Synthesis and biological evaluation of novel 3-(quinolin-4-ylamino)benzenesulfonamides as carbonic anhydrase isoforms I and II inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 1457-1464.
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Giulia Rotondi, Paolo Guglielmi, Simone Carradori, Daniela Secci, Celeste De Monte, Barbara De Filippis, Cristina Maccallini, Rosa Amoroso, Roberto Cirilli, Atilla Akdemir, Andrea Angeli & Claudiu T. Supuran. (2019) Design, synthesis and biological activity of selective hCAs inhibitors based on 2-(benzylsulfinyl)benzoic acid scaffold. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 1400-1413.
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Baijayantimala Swain, Andrea Angeli, Srinivas Angapelly, Pavitra S. Thacker, Priti Singh, Claudiu T. Supuran & Mohammed Arifuddin. (2019) Synthesis of a new series of 3-functionalised-1-phenyl-1,2,3-triazole sulfamoylbenzamides as carbonic anhydrase I, II, IV and IX inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 1199-1209.
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Articles from other publishers (128)
Noushaba Nusrat Mafy, Dorothea B. Hudson & Emily L. Que. (2024) Control of metalloenzyme activity using photopharmacophores. Coordination Chemistry Reviews 499, pages 215485.
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Claudiu T. Supuran. 2024. Metalloenzymes. Metalloenzymes
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Cüneyt Türkeş. (2023) Carbonic anhydrase inhibition by antiviral drugs in vitro and in silico. Journal of Molecular Recognition 36:12.
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Kiran Siwach, Manishita Rani, Lalit Vats, Simone Giovannuzzi, Avijit Kumar Paul, Mettle Brahma, Neetu Kumari, Mulaka Maruthi, Neera Raghav, Claudiu T. Supuran & Pawan K. Sharma. (2023) 1,2,3‐Triazole‐based esters and carboxylic acids as nonclassical carbonic anhydrase inhibitors capable of cathepsin B inhibition. Archiv der Pharmazie.
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Toni C. Denner, Andrea Angeli, Marta Ferraroni, Claudiu T. Supuran & René Csuk. (2023) Ureidobenzenesulfonamides as Selective Carbonic Anhydrase I, IX, and XII Inhibitors. Molecules 28:23, pages 7782.
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Gilberto Gastelum, Jeffry Kraut, Mysore Veena, Alisher Baibussinov, Christopher Lamb, Kylee Lyons, Eric Y. Chang & Patrick Frost. (2023) Acidification of intracellular pH in MM tumor cells overcomes resistance to hypoxia-mediated apoptosis in vitro and in vivo. Frontiers in Oncology 13.
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Samaa Saied, Moataz Shaldam, Mostafa M. Elbadawi, Simone Giovannuzzi, Alessio Nocentini, Hadia Almahli, Rofaida Salem, Tamer M. Ibrahim, Claudiu T. Supuran & Wagdy M. Eldehna. (2023) Discovery of indolinone-bearing benzenesulfonamides as new dual carbonic anhydrase and VEGFR-2 inhibitors possessing anticancer and pro-apoptotic properties. European Journal of Medicinal Chemistry 259, pages 115707.
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Lalit Vats, Priyanka Arya, Rajiv Kumar, Simone Giovannuzzi, Neera Raghav, Claudiu T Supuran & Pawan K Sharma. (2023) Keto-bridged dual triazole-linked benzenesulfonamides as potent carbonic anhydrase and cathepsin B inhibitors. Future Medicinal Chemistry.
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Zainab Kifah Abbas, Noor H. Naser & Rana Neama Atiya. (2023) IN SILICO STUDY OF NOVEL SULFONAMIDE DERIVATIVES BEARING A 1, 2, 4-TRIAZOLE MOIETY ACT AS CARBONIC ANHYDRASE INHIBITORS WITH PROMISING ANTI-CANCER ACTIVITY. Polski Merkuriusz Lekarski 51:5, pages 527-532.
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Yuewei Xu, Sarah Spear, Yurui Ma, Marc P. Lorentzen, Michael Gruet, Flora McKinney, Yitao Xu, Chiharu Wickremesinghe, Madelen R. Shepherd, Iain McNeish, Hector C. Keun & Anke Nijhuis. (2023) Pharmacological depletion of RNA splicing factor RBM39 by indisulam synergizes with PARP inhibitors in high-grade serous ovarian carcinoma. Cell Reports 42:10, pages 113307.
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Claudiu T. Supuran. (2023) A simple yet multifaceted 90 years old, evergreen enzyme: Carbonic anhydrase, its inhibition and activation. Bioorganic & Medicinal Chemistry Letters 93, pages 129411.
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Samir Bondock, Tallah Albarqi, Mohamed Abboud, Tamer Nasr, Nada M. Mohamed & Moaz M. Abdou. (2023) Tail-approach based design, synthesis, and cytotoxic evaluation of novel disubstituted and trisubstituted 1,3-thiazole benzenesulfonamide derivatives with suggested carbonic anhydrase IX inhibition mechanism. RSC Advances 13:34, pages 24003-24022.
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Yaru Li, Meiyu Feng, Tao Guo, Zheng Wang & Yanjun Zhao. (2023) Tailored Beta‐Lapachone Nanomedicines for Cancer‐Specific Therapy. Advanced Healthcare Materials 12:20.
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Wen Zhou, Chunping Wang, Bin Zhang & Shaohua Gou. (2023) Hybrids of carbonic anhydrase and cyclooxygenase inhibitors attenuate cardiac hypoxic inflammatory injuries. European Journal of Pharmacology 950, pages 175751.
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Weidong Cao, Jianqiong Yang, Chunrong Zhu, Zuhua Zeng, Chenwu Yang, Tianwu Chen & Jiang Zhu. (2023) Carbonic Anhydrase IX Targeting Mn(II)-Based Magnetic Resonance Molecular Imaging Probe for Hypoxia Tumors. Bioconjugate Chemistry 34:6, pages 1166-1175.
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Aditi Redij, Simone Carradori, Andrea Petreni, Claudiu T. Supuran & Mrunmayee P. Toraskar. (2023) Coumarin-pyrazoline Hybrids as Selective Inhibitors of the Tumor-associated
Carbonic Anhydrase IX and XII. Anti-Cancer Agents in Medicinal Chemistry 23:10, pages 1217-1223.
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Guang Huang, Tomasz Cierpicki & Jolanta Grembecka. (2023) 2-Aminobenzothiazoles in anticancer drug design and discovery. Bioorganic Chemistry 135, pages 106477.
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Jekateri̅na Ivanova, Alessio Nocentini, Kaspars Ta̅rs, Ja̅nis Leita̅ns, Elviss Dvinskis, Andris Kazaks, Ilona Domračeva, Claudiu T. Supuran & Raivis Žalubovskis. (2023) Atropo/Tropo Flexibility: A Tool for Design and Synthesis of Self-Adaptable Inhibitors of Carbonic Anhydrases and Their Antiproliferative Effect. Journal of Medicinal Chemistry 66:8, pages 5703-5718.
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Gonçalo A. Marcelo, David Montpeyó, Joana Galhano, Ramón Martínez-Máñez, José Luis Capelo-Martínez, Julia Lorenzo, Carlos Lodeiro & Elisabete Oliveira. (2023) Development of New Targeted Nanotherapy Combined with Magneto-Fluorescent Nanoparticles against Colorectal Cancer. International Journal of Molecular Sciences 24:7, pages 6612.
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Marta Venturella, Alessandro Falsini, Federica Coppola, Gaia Giuntini, Fabio Carraro, Davide Zocco, Antonio Chiesi & Antonella Naldini. (2023) CA-IX-Expressing Small Extracellular Vesicles (sEVs) Are Released by Melanoma Cells under Hypoxia and in the Blood of Advanced Melanoma Patients. International Journal of Molecular Sciences 24:7, pages 6122.
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Rui Han, Jiayin Li, Jing Hony, Zhiwei Xiao, Jinghui wang, Man Yao, Shufang Liang & Lingeng Lu. (2023) CAXII inhibitors: Potential sensitizers for immune checkpoint inhibitors in HCC treatment. Frontiers in Immunology 14.
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Morteza Abdoli, Viviana De Luca, Clemente Capasso, Claudiu T. Supuran & Raivis Žalubovskis. (2023) Inhibition Studies on Carbonic Anhydrase Isoforms I, II, IX, and XII with a Series of Sulfaguanidines. ChemMedChem 18:6.
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Seong-Ki Lee, Walter F. Boron & Rossana Occhipinti. (2023) Potential Novel Role of Membrane-Associated Carbonic Anhydrases in the Kidney. International Journal of Molecular Sciences 24:4, pages 4251.
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Atukuri Dorbabu. (2023) Pyrazole/pyrazoline as an excellent pharmacophore in the design of carbonic anhydrase inhibitors (2018–2022). Archiv der Pharmazie.
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Suzy Scholl, Diana Bello Roufai, Linda Larbi ChérifMaud Kamal. (2023) RAIDS atlas of significant genetic and protein biomarkers in cervical cancer. Journal of Gynecologic Oncology 34:5.
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Chnar Kakakhan, Cüneyt Türkeş, Özcan Güleç, Yeliz Demir, Mustafa Arslan, Gizem Özkemahlı & Şükrü Beydemir. (2023) Exploration of 1,2,3-triazole linked benzenesulfonamide derivatives as isoform selective inhibitors of human carbonic anhydrase. Bioorganic & Medicinal Chemistry 77, pages 117111.
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Claudiu T. Supuran. 2023. Nitric Oxide in Health and Disease. Nitric Oxide in Health and Disease
305
317
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Bich Phuong Bui, Phuong Linh Nguyen, Kyeong Lee & Jungsook Cho. (2022) Hypoxia-Inducible Factor-1: A Novel Therapeutic Target for the Management of Cancer, Drug Resistance, and Cancer-Related Pain. Cancers 14:24, pages 6054.
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Krishna N. Mishra & Harish C. Upadhyay. (2022) Coumarin-1,2,3-triazole hybrids as leading-edge anticancer agents. Frontiers in Drug Discovery 2.
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Claudiu T. Supuran. 2022. Flavonoids and Phenolics. Flavonoids and Phenolics
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329
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Annachiara Sarnella, Ylenia Ferrara, Luigi Auletta, Sandra Albanese, Laura Cerchia, Vincenzo Alterio, Giuseppina De Simone, Claudiu T. Supuran & Antonella Zannetti. (2022) Inhibition of carbonic anhydrases IX/XII by SLC-0111 boosts cisplatin effects in hampering head and neck squamous carcinoma cell growth and invasion. Journal of Experimental & Clinical Cancer Research 41:1.
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Shoaib Manzoor, Andrea Angeli, Susi Zara, Simone Carradori, Md Ataur Rahman, Md Kausar Raza, Claudiu T. Supuran & Nasimul Hoda. (2022) Development of benzene and benzothiazole-sulfonamide analogues as selective inhibitors of the tumor-associated carbonic anhydrase IX. European Journal of Medicinal Chemistry 243, pages 114793.
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Pavitra S. Thacker, Vaishnavi Newaskar, Andrea Angeli, Dilep Kumar Sigalapalli, Nerella Sridhar Goud, Hepsibha Chirra, Afzal B. Shaik, Mohammed Arifuddin & Claudiu T. Supuran. (2022) Synthesis and biological evaluation of coumarin‐thiazole hybrids as selective carbonic anhydrase IX and XII inhibitors. Archiv der Pharmazie 355:12.
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Laura Braconi, Elisabetta Teodori, Chiara Riganti, Marcella Coronnello, Alessio Nocentini, Gianluca Bartolucci, Marco Pallecchi, Marialessandra Contino, Dina Manetti, Maria Novella Romanelli, Claudiu T. Supuran & Silvia Dei. (2022) New Dual P-Glycoprotein (P-gp) and Human Carbonic Anhydrase XII (hCA XII) Inhibitors as Multidrug Resistance (MDR) Reversers in Cancer Cells. Journal of Medicinal Chemistry 65:21, pages 14655-14672.
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Jingjing Wang, Zhaoli Sun, Shuren Wang, Chenyang Zhao, Junjie Xu, Shen Gao, Meng Yang, Fugeng Sheng, Song Gao & Yanglong Hou. (2022) Biodegradable Ferrous Sulfide-Based Nanocomposites for Tumor Theranostics through Specific Intratumoral Acidosis-Induced Metabolic Symbiosis Disruption. Journal of the American Chemical Society 144:43, pages 19884-19895.
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Xinyang Zhong, Xuefeng He, Yaxian Wang, Zijuan Hu, Huixia Huang, Senlin Zhao, Ping Wei & Dawei Li. (2022) Warburg effect in colorectal cancer: the emerging roles in tumor microenvironment and therapeutic implications. Journal of Hematology & Oncology 15:1.
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Wen Zhou, Chunping Wang, Zhikun Liu & Shaohua Gou. (2022) Hypoxia-Activated Prodrugs with Dual COX-2/CA Inhibitory Effects on Attenuating Cardiac Inflammation under Hypoxia. Journal of Medicinal Chemistry 65:19, pages 13436-13451.
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Amit Kumar, Kiran Siwach, Claudiu T. Supuran & Pawan K. Sharma. (2022) A decade of tail-approach based design of selective as well as potent tumor associated carbonic anhydrase inhibitors. Bioorganic Chemistry 126, pages 105920.
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Phuong Linh Nguyen, Ahmed Elkamhawy, Young Hee Choi, Chang Hoon Lee, Kyeong Lee & Jungsook Cho. (2022) Suppression of Tumor Growth and Cell Migration by Indole-Based Benzenesulfonamides and Their Synergistic Effects in Combination with Doxorubicin. International Journal of Molecular Sciences 23:17, pages 9903.
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Özlen Güzel-Akdemir, Kübra Demir-Yazıcı, Daniela Vullo, Claudiu T. Supuran & Atilla Akdemir. (2022) New Pyridinium Salt Derivatives of 2-(Hydrazinocarbonyl)-3-phenyl-1H-indole-5-
sulfonamide as Selective Inhibitors of Tumour-Related Human Carbonic Anhydrase
Isoforms IX and XII. Anti-Cancer Agents in Medicinal Chemistry 22:14, pages 2637-2646.
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Qian Gao, Lirong Chen, Chenshuang Jia, Yue Yuan, Xinyao Li, Zheng Lu, Yang Feng, Ruixia Zhao, Xuewei Zhao, Yiwen Wang, Sinan Cheng, Caixia Zhang, Jie Xu, Zhan Shu, Wei Duan, Guochao Nie, Li Xiao & Yingchun Hou. (2022) Selection and identification of a specific peptide binding to ovarian cancer cells from a phage-displayed peptide library. Biotechnology Letters 44:8, pages 951-960.
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Lisa Hiepp, Doris Mayr, Kathrin Gärtner, Elisa Schmoeckel, Frederick Klauschen, Alexander Burges, Sven Mahner, Reinhard Zeidler & Bastian Czogalla. (2022) Carbonic anhydrase XII as biomarker and therapeutic target in ovarian carcinomas. PLOS ONE 17:7, pages e0271630.
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Simone Giovannuzzi, Clemente Capasso, Alessio Nocentini & Claudiu T. Supuran. (2022) Continued Structural Exploration of Sulfocoumarin as Selective Inhibitor of Tumor-Associated Human Carbonic Anhydrases IX and XII. Molecules 27:13, pages 4076.
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Yuewei Xu, Anke Nijhuis & Hector C. Keun. (2021) RNA‐binding motif protein 39 (RBM39): An emerging cancer target. British Journal of Pharmacology 179:12, pages 2795-2812.
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Moritz J. Strowitzki, Ross Nelson, Mario P. Garcia, Christopher Tuffs, Marc B. Bleul, Stephen Fitzsimons, Javier Navas, Ilona Uzieliene, Alina S. Ritter, David Phelan, Sarah J. Kierans, Alfonso Blanco, Eiva Bernotiene, Orina Belton, Martin Schneider, Eoin P. Cummins & Cormac T. Taylor. (2022) Carbon Dioxide Sensing by Immune Cells Occurs through Carbonic Anhydrase 2–Dependent Changes in Intracellular pH. The Journal of Immunology 208:10, pages 2363-2375.
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Pengcheng Lv, Yinyi Cai, Jiayi Luo & Kun Chen. (2022) Recent Advances in the Design and Synthesis of Small Molecule Carbonic
Anhydrase IX Inhibitors. Current Topics in Medicinal Chemistry 22:7, pages 550-560.
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Yuejia Dang, Yi Wei, Wajjiha Batool, Xicen Sun, Xiaoqian Li & Shi-Hong Zhang. (2022) Contribution of the Mitochondrial Carbonic Anhydrase (MoCA1) to Conidiogenesis and Pathogenesis in Magnaporthe oryzae. Frontiers in Microbiology 13.
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Ali Bahadur, Shahid Iqbal, Saiqa Muneer, Hashem O. Alsaab, Nasser S. Awwad & Hala A. Ibrahium. (2022) RETRACTED: Synthesis, carbonic anhydrase enzyme inhibition evaluations, and anticancer studies of sulfonamide based thiadiazole derivatives. Bioorganic & Medicinal Chemistry Letters 57, pages 128520.
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Simone Giovannuzzi, Mario D’Ambrosio, Cristina Luceri, Sameh Mohamed Osman, Marco Pallecchi, Gianluca Bartolucci, Alessio Nocentini & Claudiu T. Supuran. (2021) Aromatic Sulfonamides including a Sulfonic Acid Tail: New Membrane Impermeant Carbonic Anhydrase Inhibitors for Targeting Selectively the Cancer-Associated Isoforms. International Journal of Molecular Sciences 23:1, pages 461.
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Stanislav Kalinin, Anna Malkova, Tatiana Sharonova, Vladimir Sharoyko, Alexander Bunev, Claudiu T. Supuran & Mikhail Krasavin. (2021) Carbonic Anhydrase IX Inhibitors as Candidates for Combination Therapy of Solid Tumors. International Journal of Molecular Sciences 22:24, pages 13405.
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Andrea Petreni, Sameh M. Osman, Fatmah A. Alasmary, Tahani M. Almutairi, Alessio Nocentini & Claudiu T. Supuran. (2021) Binding site comparison for coumarin inhibitors and amine/amino acid activators of human carbonic anhydrases. European Journal of Medicinal Chemistry 226, pages 113875.
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Diaaeldin M. Elimam, Abdullah A. Elgazar, Alessandro Bonardi, Mohamed Abdelfadil, Alessio Nocentini, Ramadan A. El-Domany, Hatem A. Abdel-Aziz, Farid A. Badria, Claudiu T. Supuran & Wagdy M. Eldehna. (2021) Natural inspired piperine-based sulfonamides and carboxylic acids as carbonic anhydrase inhibitors: Design, synthesis and biological evaluation. European Journal of Medicinal Chemistry 225, pages 113800.
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Andrea Angeli, Victor Kartsev, Anthi Petrou, Mariana Pinteala, Volodymyr Brovarets, Roman Vydzhak, Svitlana Panchishin, Athina Geronikaki & Claudiu T. Supuran. (2021) Carbonic Anhydrase Inhibition with Sulfonamides Incorporating Pyrazole- and Pyridazinecarboxamide Moieties Provides Examples of Isoform-Selective Inhibitors. Molecules 26:22, pages 7023.
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Dmitry Dar'in, Grigory Kantin, Stanislav Kalinin, Tatiana Sharonova, Alexander Bunev, Gennady I. Ostapenko, Alessio Nocentini, Vladimir Sharoyko, Claudiu T. Supuran & Mikhail Krasavin. (2021) Investigation of 3-sulfamoyl coumarins against cancer-related IX and XII isoforms of human carbonic anhydrase as well as cancer cells leads to the discovery of 2-oxo-2H-benzo[h]chromene-3-sulfonamide – A new caspase-activating proapoptotic agent. European Journal of Medicinal Chemistry 222, pages 113589.
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Ziwei Jing, Xiaohui Wang, Na Li, Zhi Sun, Dingding Zhang, Lin Zhou, Fanxiang Yin, Qingquan Jia, Mengli Wang, Yaojuan Chu, Shuzhang Du, Yaping He, Qiuzheng Du & Xiaojian Zhang. (2021) Ultrasound‐guided percutaneous metal‐organic frameworks based codelivery system of doxorubicin/acetazolamide for hepatocellular carcinoma therapy. Clinical and Translational Medicine 11:10.
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Dilara Fatma AKIN & Rahsan ILIKCI. (2021) Mutations and expression profile of EDIL3 and correlation with HIF1A and tumor-associated carbonic anhydrases in pancreatic cancer. Clinical and Experimental Health Sciences 11:3, pages 418-425.
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Yassine Aimene, Romain Eychenne, Frédéric Rodriguez, Sonia Mallet-Ladeira, Nathalie Saffon-Merceron, Jean-Yves Winum, Alessio Nocentini, Claudiu T. Supuran, Eric Benoist & Achour Seridi. (2021) Synthesis, Crystal Structure, Inhibitory Activity and Molecular Docking of Coumarins/Sulfonamides Containing Triazolyl Pyridine Moiety as Potent Selective Carbonic Anhydrase IX and XII Inhibitors. Crystals 11:9, pages 1076.
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Mudasir Nabi Peerzada, Ernest Hamel, Ruoli Bai, Claudiu T. Supuran & Amir Azam. (2021) Deciphering the key heterocyclic scaffolds in targeting microtubules, kinases and carbonic anhydrases for cancer drug development. Pharmacology & Therapeutics 225, pages 107860.
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Iryna Antal, Martina Koneracka, Martina Kubovcikova, Vlasta Zavisova, Alena Jurikova, Iryna Khmara, Maria Omastova, Matej Micusik, Monika Barathova, Lenka Jelenska, Ivana Kajanova, Miriam Zatovicova & Silvia Pastorekova. (2021) Targeting of carbonic anhydrase IX-positive cancer cells by glycine-coated superparamagnetic nanoparticles. Colloids and Surfaces B: Biointerfaces 205, pages 111893.
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Silvia A. Teixeira, Mariano S. Viapiano, Augusto F. Andrade, Mohan S. Nandhu, Julia A. Pezuk, Lucas T. Bidinotto, Veridiana K. Suazo, Luciano Neder, Carlos G. Carlotti, Aline P. Becker, Luiz Gonzaga Tone & Carlos A. Scrideli. (2021) The Carbonic Anhydrase Inhibitor E7070 Sensitizes Glioblastoma Cells to Radio- and Chemotherapy and Reduces Tumor Growth. Molecular Neurobiology 58:9, pages 4520-4534.
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Andrea Angeli, Victor Kartsev, Anthi Petrou, Mariana Pinteala, Roman M. Vydzhak, Svitlana Y. Panchishin, Volodymyr Brovarets, Viviana De Luca, Clemente Capasso, Athina Geronikaki & Claudiu T. Supuran. (2021) New Sulfanilamide Derivatives Incorporating Heterocyclic Carboxamide Moieties as Carbonic Anhydrase Inhibitors. Pharmaceuticals 14:8, pages 828.
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Andrea Angeli, Mariana Pinteala, Stelian S. Maier, Alessandra Toti, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Silvia Selleri, Fabrizio Carta & Claudiu T. Supuran. (2021) Tellurides bearing benzensulfonamide as carbonic anhydrase inhibitors with potent antitumor activity. Bioorganic & Medicinal Chemistry Letters 45, pages 128147.
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Kalyan Sethi, KM Mishra, Saurabh Verma, Daniela Vullo, Fabrizio Carta & Claudiu Supuran. (2021) Synthesis and Human Carbonic Anhydrase I, II, IX, and XII Inhibition Studies of Sulphonamides Incorporating Mono-, Bi- and Tricyclic Imide Moieties. Pharmaceuticals 14:7, pages 693.
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Gilberto Gastelum, Mysore Veena, Kylee Lyons, Christopher Lamb, Nicole Jacobs, Alexandra Yamada, Alisher Baibussinov, Martin Sarafyan, Rebeka Shamis, Jeffry Kraut & Patrick Frost. (2021) Can Targeting Hypoxia-Mediated Acidification of the Bone Marrow Microenvironment Kill Myeloma Tumor Cells?. Frontiers in Oncology 11.
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Tatiana Sharonova, Polina Paramonova, Stanislav Kalinin, Alexander Bunev, Rovshan Е. Gasanov, Alessio Nocentini, Vladimir Sharoyko, Tatiana B. Tennikova, Dmitry Dar’in, Claudiu T. Supuran & Mikhail Krasavin. (2021) Insertion of metal carbenes into the anilinic N–H bond of unprotected aminobenzenesulfonamides delivers low nanomolar inhibitors of human carbonic anhydrase IX and XII isoforms. European Journal of Medicinal Chemistry 218, pages 113352.
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Elmas Begum Cakmak, Belma Zengin Kurt, Dilek Ozturk Civelek, Andrea Angeli, Atilla Akdemir, Fatih Sonmez, Claudiu T. Supuran & Mustafa Kucukislamoglu. (2021) Quinoline-sulfamoyl carbamates/sulfamide derivatives: Synthesis, cytotoxicity, carbonic anhydrase activity, and molecular modelling studies. Bioorganic Chemistry 110, pages 104778.
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Moataz Shaldam, Wagdy M. Eldehna, Alessio Nocentini, Zainab M. Elsayed, Tamer M. Ibrahim, Rofaida Salem, Ramadan A. El-Domany, Clemente Capasso, Hatem A. Abdel-Aziz & Claudiu T. Supuran. (2021) Development of novel benzofuran-based SLC-0111 analogs as selective cancer-associated carbonic anhydrase isoform IX inhibitors. European Journal of Medicinal Chemistry 216, pages 113283.
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Peijie Wu, Wei Gao, Miao Su, Edouard C. Nice, Wenhui Zhang, Jie Lin & Na Xie. (2021) Adaptive Mechanisms of Tumor Therapy Resistance Driven by Tumor Microenvironment. Frontiers in Cell and Developmental Biology 9.
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Valeria Burianova, Stanislav Kalinin, Claudiu T. Supuran & Mikhail Krasavin. (2021) Radiotracers for positron emission tomography (PET) targeting tumour-associated carbonic anhydrase isoforms. European Journal of Medicinal Chemistry 213, pages 113046.
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Carolina Bernauer, Y. K. Stella Man, Julia C. Chisholm, Elise Y. Lepicard, Simon P. Robinson & Janet M. Shipley. (2020) Hypoxia and its therapeutic possibilities in paediatric cancers. British Journal of Cancer 124:3, pages 539-551.
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Tuna DEMİRCİ, Oğuzhan ÖZDEMİR, Mustafa Oğuzhan KAYA & Mustafa ARSLAN. (2021) Synthesis and Biological Evaluation of Novel Dihydro [2,3D] Pyridine Substituted Enaminosulfonamide Compounds as Potent Human Erythrocyte Carbonic Anhydrase II (hCAII). Sakarya University Journal of Science 25:1, pages 200-211.
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Eva Havránková, E.M. Peña-Méndez, Jozef Csöllei & Josef Havel. (2021) Prediction of biological activity of compounds containing a 1,3,5-triazinyl sulfonamide scaffold by artificial neural networks using simple molecular descriptors. Bioorganic Chemistry 107, pages 104565.
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Andrea Angeli, Fabrizio Carta, Alessio Nocentini, Jean-Yves Winum, Raivis Zalubovskis, Valentina Onnis, Wagdy M. Eldehna, Clemente Capasso, Simone Carradori, William A. Donald, Shoukat Dedhar & Claudiu T. Supuran. (2021) Response to Perspectives on the Classical Enzyme Carbonic Anhydrase and the Search for Inhibitors. Biophysical Journal 120:1, pages 178-181.
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Simone Carradori & Claudiu T. Supuran. 2021. pH-Interfering Agents as Chemosensitizers in Cancer Therapy. pH-Interfering Agents as Chemosensitizers in Cancer Therapy
79
94
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Fabrizio Carta, Daniela Vullo & Andrea Angeli. 2021. pH-Interfering Agents as Chemosensitizers in Cancer Therapy. pH-Interfering Agents as Chemosensitizers in Cancer Therapy
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78
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Jean-Yves Winum. 2021. pH-Interfering Agents as Chemosensitizers in Cancer Therapy. pH-Interfering Agents as Chemosensitizers in Cancer Therapy
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Claudiu T. Supuran. 2021. The Carbonic Anhydrases: Current and Emerging Therapeutic Targets. The Carbonic Anhydrases: Current and Emerging Therapeutic Targets
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Claudiu T. Supuran. 2021. New Trends in Macromolecular and Supramolecular Chemistry for Biological Applications. New Trends in Macromolecular and Supramolecular Chemistry for Biological Applications
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131
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Tomas Koltai. (2020) Targeting the pH Paradigm at the Bedside: A Practical Approach. International Journal of Molecular Sciences 21:23, pages 9221.
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Geetha Venkateswaran & Shoukat Dedhar. (2020) Interplay of Carbonic Anhydrase IX With Amino Acid and Acid/Base Transporters in the Hypoxic Tumor Microenvironment. Frontiers in Cell and Developmental Biology 8.
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Lisa Annabel Weber, Anne Funtan, Reinhard Paschke, Julien Delarocque, Jutta Kalbitz, Jessica Meißner, Karsten Feige, Manfred Kietzmann & Jessika-Maximiliane V. Cavalleri. (2020) In vitro assessment of triterpenoids NVX-207 and betulinyl-bis-sulfamate as a topical treatment for equine skin cancer. PLOS ONE 15:11, pages e0241448.
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Lilia Clima, Bogdan Florin Craciun, Andrea Angeli, Andrea Petreni, Alessandro Bonardi, Alessio Nocentini, Fabrizio Carta, Paola Gratteri, Mariana Pinteala & Claudiu T. Supuran. (2020)
Synthesis, Computational Studies and Assessment of
in Vitro
Activity of Squalene Derivatives as Carbonic Anhydrase Inhibitors
. ChemMedChem 15:21, pages 2052-2057.
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Chandra B. Mishra, Manisha Tiwari & Claudiu T. Supuran. (2020) Progress in the development of human carbonic anhydrase inhibitors and their pharmacological applications: Where are we today?. Medicinal Research Reviews 40:6, pages 2485-2565.
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Baptiste Gouyou, Jacopo Millul, Alessandra Villa, Samuele Cazzamalli, Dario Neri & Mattia Matasci. (2020) Sortase-Mediated Site-Specific Modification of Interleukin-2 for the Generation of a Tumor-Targeting Acetazolamide–Cytokine Conjugate. ACS Omega 5:40, pages 26077-26083.
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Suleyman Akocak, Özlen Güzel-Akdemir, Rajesh Kishore Kumar Sanku, Samson S. Russom, Bogdan I. Iorga, Claudiu T. Supuran & Marc A. Ilies. (2020) Pyridinium derivatives of 3-aminobenzenesulfonamide are nanomolar-potent inhibitors of tumor-expressed carbonic anhydrase isozymes CA IX and CA XII. Bioorganic Chemistry 103, pages 104204.
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Yosselin Huentupil, Patricio Chung, Néstor Novoa, Rodrigo Arancibia, Pascal Roussel, Juan Oyarzo, A. Hugo Klahn, Carlos Silva, Carme Calvis, Ramon Messeguer, Ramón Bosque & Concepción López. (2020)
Novel multifunctional and multitarget homo- (Fe
2
) and heterobimetallic [(Fe,M) with M = Re or Mn] sulfonyl hydrazones
. Dalton Transactions 49:35, pages 12249-12265.
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Shirley Genah, Andrea Angeli, Claudiu T. Supuran & Lucia Morbidelli. (2020) Effect of Carbonic Anhydrase IX inhibitors on human endothelial cell survival. Pharmacological Research 159, pages 104964.
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Costanza Ceni, Daniela Catarzi, Flavia Varano, Diego Dal Ben, Gabriella Marucci, Michela Buccioni, Rosaria Volpini, Andrea Angeli, Alessio Nocentini, Paola Gratteri, Claudiu T. Supuran & Vittoria Colotta. (2020) Discovery of first-in-class multi-target adenosine A2A receptor antagonists-carbonic anhydrase IX and XII inhibitors. 8-Amino-6-aryl-2-phenyl-1,2,4-triazolo [4,3-a]pyrazin-3-one derivatives as new potential antitumor agents. European Journal of Medicinal Chemistry 201, pages 112478.
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Aiga Grandāne, Alessio Nocentini, Ilona Domračeva, Raivis Žalubovskis & Claudiu T. Supuran. (2020) Development of oxathiino[6,5-b]pyridine 2,2-dioxide derivatives as selective inhibitors of tumor-related carbonic anhydrases IX and XII. European Journal of Medicinal Chemistry 200, pages 112300.
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Baijayantimala Swain, Andrea Angeli, Priti Singh, Claudiu T. Supuran & Mohammed Arifuddin. (2020) New coumarin/sulfocoumarin linked phenylacrylamides as selective transmembrane carbonic anhydrase inhibitors: Synthesis and in-vitro biological evaluation. Bioorganic & Medicinal Chemistry 28:15, pages 115586.
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Tianyu Zheng, Marja Jäättelä & Bin Liu. (2020) pH gradient reversal fuels cancer progression. The International Journal of Biochemistry & Cell Biology 125, pages 105796.
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Gábor Méhes, Orsolya Matolay, Lívia Beke, Marianna Czenke, Róbert Pórszász, Edit Mikó, Péter Bai, Ervin Berényi & György Trencsényi. (2020) Carbonic Anhydrase Inhibitor Acetazolamide Enhances CHOP Treatment Response and Stimulates Effector T-Cell Infiltration in A20/BalbC Murine B-Cell Lymphoma. International Journal of Molecular Sciences 21:14, pages 5001.
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Shen-Han Lee & John R. Griffiths. (2020) How and Why Are Cancers Acidic? Carbonic Anhydrase IX and the Homeostatic Control of Tumour Extracellular pH. Cancers 12:6, pages 1616.
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Mária Bodnár Mikulová, Dáša Kružlicová, Daniel Pecher, Claudiu T. Supuran & Peter Mikuš. (2020) Synthetic Strategies and Computational Inhibition Activity Study for Triazinyl-Substituted Benzenesulfonamide Conjugates with Polar and Hydrophobic Amino Acids as Inhibitors of Carbonic Anhydrases. International Journal of Molecular Sciences 21:10, pages 3661.
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Emilie Anduran, Ashok Aspatwar, Nanda-Kumar Parvathaneni, Dennis Suylen, Silvia Bua, Alessio Nocentini, Seppo Parkkila, Claudiu T. Supuran, Ludwig Dubois, Philippe Lambin & Jean-Yves Winum. (2020) Hypoxia-Activated Prodrug Derivatives of Carbonic Anhydrase Inhibitors in Benzenesulfonamide Series: Synthesis and Biological Evaluation. Molecules 25:10, pages 2347.
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Wagdy M. Eldehna, Alessio Nocentini, Zainab M. Elsayed, Tarfah Al-Warhi, Nada Aljaeed, Ohoud J. Alotaibi, Mohammad M. Al-Sanea, Hatem A. Abdel-Aziz & Claudiu T. Supuran. (2020) Benzofuran-Based Carboxylic Acids as Carbonic Anhydrase Inhibitors and Antiproliferative Agents against Breast Cancer. ACS Medicinal Chemistry Letters 11:5, pages 1022-1027.
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Andrea Angeli, Fabrizio Carta, Selene Donnini, Antonella Capperucci, Marta Ferraroni, Damiano Tanini & Claudiu T. Supuran. (2020) Selenolesterase enzyme activity of carbonic anhydrases. Chemical Communications 56:32, pages 4444-4447.
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Enrico Luchinat, Letizia Barbieri, Matteo Cremonini, Alessio Nocentini, Claudiu T. Supuran & Lucia Banci. (2020) Drug Screening in Human Cells by NMR Spectroscopy Allows the Early Assessment of Drug Potency. Angewandte Chemie International Edition 59:16, pages 6535-6539.
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Enrico Luchinat, Letizia Barbieri, Matteo Cremonini, Alessio Nocentini, Claudiu T. Supuran & Lucia Banci. (2020) Drug Screening in Human Cells by NMR Spectroscopy Allows the Early Assessment of Drug Potency. Angewandte Chemie 132:16, pages 6597-6601.
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Elisabetta Teodori, Laura Braconi, Silvia Bua, Andrea Lapucci, Gianluca Bartolucci, Dina Manetti, Maria Novella Romanelli, Silvia Dei, Claudiu T. Supuran & Marcella Coronnello. (2020) Dual P-Glycoprotein and CA XII Inhibitors: A New Strategy to Reverse the P-gp Mediated Multidrug Resistance (MDR) in Cancer Cells. Molecules 25:7, pages 1748.
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Melissa D’Ascenzio, Daniela Secci, Simone Carradori, Susi Zara, Paolo Guglielmi, Roberto Cirilli, Marco Pierini, Giulio Poli, Tiziano Tuccinardi, Andrea Angeli & Claudiu T. Supuran. (2020) 1,3-Dipolar Cycloaddition, HPLC Enantioseparation, and Docking Studies of Saccharin/Isoxazole and Saccharin/Isoxazoline Derivatives as Selective Carbonic Anhydrase IX and XII Inhibitors. Journal of Medicinal Chemistry 63:5, pages 2470-2488.
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Daniela Vullo, Ronny Lehneck, William A. Donald, Stefanie Pöggeler & Claudiu T. Supuran. (2020) Sulfonamide Inhibition Studies of the β-Class Carbonic Anhydrase CAS3 from the Filamentous Ascomycete Sordaria macrospora. Molecules 25:5, pages 1036.
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Nerella Sridhar Goud, Raman Kumar Joshi, Rose Dawn Bharath & Pardeep Kumar. (2020) Fluorine-18: A radionuclide with diverse range of radiochemistry and synthesis strategies for target based PET diagnosis. European Journal of Medicinal Chemistry 187, pages 111979.
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Holger M. Becker. (2019) Carbonic anhydrase IX and acid transport in cancer. British Journal of Cancer 122:2, pages 157-167.
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Akhila Mettu, Venu Talla, Soujanya Thumma & Subhashini Naikal James Prameela. (2020) Mechanistic investigations on substituted benzene sulphonamides as apoptosis inducing anticancer agents. Bioorganic Chemistry 95, pages 103539.
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Fátima Baltazar, Diana Valente, Julieta Afonso, Odília Queirós & Sara Granja. 2020. An Innovative Approach to Understanding and Treating Cancer: Targeting pH. An Innovative Approach to Understanding and Treating Cancer: Targeting pH
417
450
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Tomas Koltai, Stephan J. Reshkin & Salvador Harguindey. 2020. An Innovative Approach to Understanding and Treating Cancer: Targeting pH. An Innovative Approach to Understanding and Treating Cancer: Targeting pH
157
176
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Narayan Sugandha, Lovika Mittal, Amit Awasthi & Shailendra Asthana. 2020. Cancer Cell Metabolism: A Potential Target for Cancer Therapy. Cancer Cell Metabolism: A Potential Target for Cancer Therapy
103
126
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Reza Bayat Mokhtari, Narges Baluch, Evgeniya Morgatskaya, Sushil Kumar, Angelo Sparaneo, Lucia Anna Muscarella, Sheyun Zhao, Hai-Ling Cheng, Bikul Das & Herman Yeger. (2019) Human bronchial carcinoid tumor initiating cells are targeted by the combination of acetazolamide and sulforaphane. BMC Cancer 19:1.
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Hatem E. Gaffer. (2019) Antimicrobial sulphonamide azo dyes. Coloration Technology 135:6, pages 484-500.
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Damiano Tanini, Lorenzo Ricci, Antonella Capperucci, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Thomas S. Peat, Fabrizio Carta, Andrea Angeli & Claudiu T. Supuran. (2019) Synthesis of novel tellurides bearing benzensulfonamide moiety as carbonic anhydrase inhibitors with antitumor activity. European Journal of Medicinal Chemistry 181, pages 111586.
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