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Current Medical Research and Opinion Volume 24, 2008 - Issue 4
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Review

Topical diclofenac and its role in pain and inflammation: an evidence-based review

J. Zacher Department of Orthopedic Surgery and Orthopedic RheumatologyHELIOS Hospital Group BerlinGermany
,
R. Altman Division of Rheumatology and ImmunologyUniversity of California Los Angeles, CAUSACorrespondence[email protected]
,
N. Bellamy Centre of National Research on Disability and Rehabilitation Medicine, Faculty of Health SciencesUniversity of QueenslandAustralia
,
P. Brühlmann Department of Rheumatology and Institute of Physical MedicineUniversity Hospital ZurichSwitzerland
,
J. Da SilvaUniversity Hospital CoimbraPortugal
,
E. HuskissonThe London Clinic LondonUK
&
R. S. Taylor Peninsula Medical SchoolUniversity of Exeter ExeterUK
 show all
Pages 925-950 | Accepted 04 Jan 2008, Published online: 06 Feb 2008

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Martina Hagen & Mark Baker. (2017) Skin penetration and tissue permeation after topical administration of diclofenac. Current Medical Research and Opinion 33:9, pages 1623-1634.
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Casilda M Balmaceda. (2014) Clinical trial data in support of changing guidelines in osteoarthritis treatment. Journal of Pain Research 7, pages 211-218.
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R.S. Taylor, G. Fotopoulos & H. Maibach. (2011) Safety profile of topical diclofenac: a meta-analysis of blinded, randomized, controlled trials in musculoskeletal conditions. Current Medical Research and Opinion 27:3, pages 605-622.
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David R Lionberger & Michael J Brennan. (2010) Topical nonsteroidal anti-inflammatory drugs for the treatment of pain due to soft tissue injury: diclofenac epolamine topical patch. Journal of Pain Research 3, pages 223-233.
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Tong J. Gan. (2010) Diclofenac: an update on its mechanism of action and safety profile. Current Medical Research and Opinion 26:7, pages 1715-1731.
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Edgar A Mueller, Wilhelm Kirch & Susanne Reiter. (2010) Extent and time course of pain intensity upon treatment with a topical diclofenac sodium patch versus placebo in acute traumatic injury based on a validated end point: post hoc analysis of a randomized placebo-controlled trial. Expert Opinion on Pharmacotherapy 11:4, pages 493-498.
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Rajitkanok Amy Puenpatom & Timothy W. Victor. (2009) Increased Prevalence of Metabolic Syndrome in Individuals with Osteoarthritis: An Analysis of NHANES III Data. Postgraduate Medicine 121:6, pages 9-20.
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Maggi Banning. (2008) Topical diclofenac: clinical effectiveness and current uses in osteoarthritis of the knee and soft tissue injuries. Expert Opinion on Pharmacotherapy 9:16, pages 2921-2929.
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K. D. Rainsford, W. F. Kean & G. E. Ehrlich. (2008) Review of the pharmaceutical properties and clinical effects of the topical NSAID formulation, diclofenac epolamine. Current Medical Research and Opinion 24:10, pages 2967-2992.
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