1,336
Views
110
CrossRef citations to date
0
Altmetric
Reviews

Biological activities of guanidine compounds

&
Pages 1417-1448 | Published online: 28 Sep 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Wafa Tachoua, Mohamed Kabrine, Mamona Mushtaq, Ahmed Selmi & Zaheer Ul-Haq. (2023) Highlights in TMPRSS2 inhibition mechanism with guanidine derivatives approved drugs for COVID-19 treatment. Journal of Biomolecular Structure and Dynamics 41:22, pages 12908-12922.
Read now
Mei Lu, Haonan Xing, Lin Cheng, Hui Liu, Lang Lang, Tianzhi Yang, Xiaoyun Zhao, Hui Xu & Pingtian Ding. (2020) A dual-functional buformin-mimicking poly(amido amine) for efficient and safe gene delivery. Journal of Drug Targeting 28:9, pages 923-932.
Read now
Bo Wu, Hongwei Yang, Yongxing Tang, Zhixin Wang, Chunxu Lu & Guangbin Cheng. (2015) New Energetic Derivatives of 1-Amino-3-Nitroguanidine. Journal of Energetic Materials 33:3, pages 180-190.
Read now
Muhammad Khawar Rauf, Imtiaz-ud-Din & Amin Badshah. (2014) Novel approaches to screening guanidine derivatives. Expert Opinion on Drug Discovery 9:1, pages 39-53.
Read now
Franciszek Sączewski & Łukasz Balewski. (2013) Biological activities of guanidine compounds, 2008 – 2012 update. Expert Opinion on Therapeutic Patents 23:8, pages 965-995.
Read now
SophiaK. Philip & K.N. Rajasekharan. (2011) Ecofriendly Synthesis of Novel Benzo-1,2,3-triazol-1-yl-(N-aryl)amidines and Their Conversion to Guanidines. Synthetic Communications 41:11, pages 1593-1602.
Read now

Articles from other publishers (104)

Andreea Dumitrescu, Catalin Maxim, Mihaela Badea, Arpad Mihai Rostas, Alexandra Ciorîță, Alina Tirsoaga & Rodica Olar. (2023) Decavanadate-Bearing Guanidine Derivatives Developed as Antimicrobial and Antitumor Species. International Journal of Molecular Sciences 24:24, pages 17137.
Crossref
Almudena del Campo-Balguerías, Blanca Parra-Cadenas, Cristina Nieto-Jimenez, Iván Bravo, Consuelo Ripoll, Elisa Poyatos-Racionero, Pawel Gancarski, Fernando Carrillo-Hermosilla, Carlos Alonso-Moreno & Alberto Ocaña. (2023) Guanylation Reactions for the Rational Design of Cancer Therapeutic Agents. International Journal of Molecular Sciences 24:18, pages 13820.
Crossref
Natalia C. S. Costa, Luana Ribeiro dos Anjos, João Victor Marcelino de Souza, Maria Carolina Oliveira de Arruda Brasil, Vitor Partite Moreira, Marcia A. S. Graminha, Gert Lubec, Eduardo Rene P. Gonzalez & Eduardo Maffud Cilli. (2023) Development of New Leishmanicidal Compounds via Bioconjugation of Antimicrobial Peptides and Antileishmanial Guanidines. ACS Omega.
Crossref
Ana R. Gomes, Carla L. Varela, Ana S. Pires, Elisiário J. Tavares-da-Silva & Fernanda M.F. Roleira. (2023) Synthetic and natural guanidine derivatives as antitumor and antimicrobial agents: A review. Bioorganic Chemistry 138, pages 106600.
Crossref
Martha C. Rosales-Hernández, Jessica E. Mendieta-Wejebe, Feliciano Tamay-Cach & Alejandro Cruz. (2023) Synthetic Procedures to Access 2-Guanidinobenzazoles of Biological Interest. Current Organic Synthesis 20:5, pages 504-522.
Crossref
R. Durga Priyadharshini, P. N. Sathishkumar, M. Bensingh, N. Bhuvanesh, K. N. Vennila, R. Karvembu & Kuppanagounder P. Elango. (2023) N , N ′, N ′′-Trisubstituted guanidine derivatives as DNA-intercalators: synthesis, crystal structures and biophysical investigations . New Journal of Chemistry 47:30, pages 14185-14194.
Crossref
Ratna Babu Gunturu, Prasanna Babu Racheeti, Srinivasa Rao Pinapati, Anitha Kowthalam, Ramana Tamminana & Rameshraju Rudraraju. (2023) Iron-promoted environmentally benign construction of 2-iodo aroylguanidines and 2-iodo aroyltetrazoles. Journal of Chemical Sciences 135:3.
Crossref
Ivana Antol, Zoran Glasovac & Davor Margetić. (2023) Mechanistic DFT Study of 1,3-Dipolar Cycloadditions of Azides with Guanidine. Molecules 28:5, pages 2342.
Crossref
Nathan P. Bessen, Alexander S. Ivanov, Dia̅na Stamberga, Vyacheslav S. Bryantsev & Bruce A. Moyer. (2023) Lipophilic Guanidine with Enhanced Stability for Use in Cesium Separation from Legacy High-Level Nuclear Waste. Industrial & Engineering Chemistry Research 62:8, pages 3684-3694.
Crossref
Zohreh Esam, Malihe Akhavan, Maryam Lotfi, Saeed Pourmand & Ahmadreza Bekhradnia. (2022) In silico investigation of the therapeutic and prophylactic potential of medicinal substances bearing guanidine moieties against COVID-19. Chemical Papers 77:2, pages 1129-1148.
Crossref
Martha Cecilia Rosales-Hernández, Alejandro Cruz, Jessica Elena Mendieta-Wejebe & Feliciano Tamay-Cach. (2023) 2-Guanidinobenzazoles as Building Blocks to Afford Biologically Active Derivatives. Current Organic Chemistry 27:1, pages 38-54.
Crossref
Nirali Pandya, Reshma Rani, Vinit Kumar & Amit Kumar. (2023) Discovery of a potent Guanidine derivative that selectively binds and stabilizes the human BCL-2 G-quadruplex DNA and downregulates the transcription. Gene 851, pages 146975.
Crossref
Nirali Pandya, Mamta Singh, Reshma Rani, Vinit Kumar & Amit Kumar. (2023) G-quadruplex-mediated specific recognition, stabilization and transcriptional repression of bcl-2 by small molecule. Archives of Biochemistry and Biophysics 734, pages 109483.
Crossref
Petar Štrbac, Anamarija Briš & Davor Margetić. (2022) N,N′-Di-Boc-2H-Isoindole-2-carboxamidine—First Guanidine-Substituted Isoindole. Molecules 27:24, pages 8954.
Crossref
Kushal Singh, Aswathy N. Muttathukattil, Prashant Chandra Singh & Govardhan Reddy. (2022) pH Regulates Ligand Binding to an Enzyme Active Site by Modulating Intermediate Populations. The Journal of Physical Chemistry B 126:47, pages 9759-9770.
Crossref
Michael Tapera, Hüseyin Kekeçmuhammed, Kader Sahin, Vagolu Siva Krishna, Christian Lherbet, Håvard Homberset, Mélina Chebaiki, Tone Tønjum, Lionel Mourey, Yunus Zorlu, Serdar Durdagi & Emin Sarıpınar. (2022) Synthesis, characterization, anti-tuberculosis activity and molecular modeling studies of thiourea derivatives bearing aminoguanidine moiety. Journal of Molecular Structure 1270, pages 133899.
Crossref
Jing Li, Ru Si, Qingqing Zhang, Yanchen Li, Jie Zhang & Yuanyuan Shan. (2022) Novel indole-guanidine hybrids as potential anticancer agents: Design, synthesis and biological evaluation. Chemico-Biological Interactions 368, pages 110242.
Crossref
Simon D. P. Baugh. (2022) Guanidine-Containing Antifungal Agents against Human-Relevant Fungal Pathogens (2004–2022)—A Review. Journal of Fungi 8:10, pages 1085.
Crossref
Renata Paprocka, Małgorzata Wiese-Szadkowska, Tomasz Kosmalski, Daria Frisch, Magdalena Ratajczak, Bożena Modzelewska-Banachiewicz & Renata Studzińska. (2022) A Review of the Biological Activity of Amidrazone Derivatives. Pharmaceuticals 15:10, pages 1219.
Crossref
Jinchao Lou, Megan L. Qualls, Macy M. Hudson, Dillon P. McBee, Joshua A. Baccile & Michael D. Best. (2022) Reactive Oxygen Species (ROS) Activated Liposomal Cell Delivery using a Boronate‐Caged Guanidine Lipid. Chemistry – A European Journal 28:46.
Crossref
Andreia Fortuna, Rita Gonçalves‐Pereira, Paulo J. Costa, Radek Jorda, Veronika Vojáčková, Gabriel Gonzalez, Niels V. Heise, René Csuk, M. Conceição Oliveira & Nuno M. Xavier. (2022) Synthesis and Exploitation of the Biological Profile of Novel Guanidino Xylofuranose Derivatives**. ChemMedChem 17:14.
Crossref
Yu-Tong Ye, Hai Zhang, Jun-Ling Deng, Mi-Zhuan Li & Zhong-Xiu Chen. (2022) l-Arginine inhibits the activity of α-amylase: Rapid kinetics, interaction and functional implications. Food Chemistry 380, pages 131836.
Crossref
Arruje Hameed, Muhammad Abdul Qayyum, Abdur Rehman, Touseef Ur Rehman, Anwar Ahmad & Tahir Farooq. 2022. More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles. More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles 671 687 .
Endri Karaj, Samkeliso Dlamini, Radhika Koranne, Shaimaa H. Sindi, Lalith Perera, William R. Taylor & L.M. Viranga Tillekeratne. (2022) Pharmacophore optimization of imidazole chalcones to modulate microtubule dynamics. Bioorganic Chemistry 122, pages 105700.
Crossref
Moorthy Maruthapandi, Arumugam Saravanan, Akanksha Gupta, John H. T. Luong & Aharon Gedanken. (2022) Antimicrobial Activities of Conducting Polymers and Their Composites. Macromol 2:1, pages 78-99.
Crossref
Fatima Doganc, Ismail Celik, Gokcen Eren, Marcel Kaiser, Reto Brun & Hakan Goker. (2021) Synthesis, in vitro antiprotozoal activity, molecular docking and molecular dynamics studies of some new monocationic guanidinobenzimidazoles. European Journal of Medicinal Chemistry 221, pages 113545.
Crossref
Fei Wang, Abulimiti Yumaier & Abudureheman Wusiman. (2021) Facile one-pot synthesis of tetrasubstituted N-sulfonylguanidines from sulfonamides and ureas. Monatshefte für Chemie - Chemical Monthly 152:8, pages 993-999.
Crossref
Nikos Kühl, Mila M. Leuthold, Mira A. M. Behnam & Christian D. Klein. (2021) Beyond Basicity: Discovery of Nonbasic DENV-2 Protease Inhibitors with Potent Activity in Cell Culture. Journal of Medicinal Chemistry 64:8, pages 4567-4587.
Crossref
Valentina Albanese, Chiara Ruzza, Erika Marzola, Tatiana Bernardi, Martina Fabbri, Anna Fantinati, Claudio Trapella, Rainer K. Reinscheid, Federica Ferrari, Chiara Sturaro, Girolamo Calò, Giorgio Amendola, Sandro Cosconati, Salvatore Pacifico, Remo Guerrini & Delia Preti. (2021) Structure–Activity Relationship Studies on Oxazolo[3,4- a ]pyrazine Derivatives Leading to the Discovery of a Novel Neuropeptide S Receptor Antagonist with Potent In Vivo Activity . Journal of Medicinal Chemistry 64:7, pages 4089-4108.
Crossref
Seong-Heun Kim, Dorothy Semenya & Daniele Castagnolo. (2021) Antimicrobial drugs bearing guanidine moieties: A review. European Journal of Medicinal Chemistry 216, pages 113293.
Crossref
Patricia B. Gratal, Julia G. Quero, Adrián Pérez-Redondo, Zoila Gándara & Lourdes Gude. (2021) PhenQE8, a Novel Ligand of the Human Telomeric Quadruplex. International Journal of Molecular Sciences 22:2, pages 749.
Crossref
Shao-Hua Wang, Kuan Wang, Ke Zhao, Shu-Cheng Hua & Juan Du. (2020) The Structure, Function, and Mechanisms of Action of Enterovirus Non-structural Protein 2C. Frontiers in Microbiology 11.
Crossref
S. N. K. Kurtar, F. Koçer & M. Kose. (2020) MONOMERIC AND 1D POLYMERIC Cu(II) COMPLEXES DERIVED FROM DICYANAMIDE: STRUCTURAL CHARACTERIZATION AND ANTIBACTERIAL PROPERTIES. Journal of Structural Chemistry 61:8, pages 1296-1305.
Crossref
Tom Baladi, Nedra Hamouda‐Tekaya, Leticia Christina Pires Gonçalves, Stéphane Rocchi, Cyril Ronco & Rachid Benhida. (2020) Sulfonylguanidine Derivatives as Potential Antimelanoma Agents. ChemMedChem 15:13, pages 1113-1117.
Crossref
Raghunandan Yendapally, Donald Sikazwe, Subin S. Kim, Sushma Ramsinghani, Rheaclare Fraser‐Spears, Amy P. Witte & Brittany La‐Viola. (2020) A review of phenformin, metformin, and imeglimin. Drug Development Research 81:4, pages 390-401.
Crossref
Roman Blaszczyk, Joanna Brzezinska, Barbara Dymek, Paulina S. Stanczak, Marcin Mazurkiewicz, Jacek Olczak, Julita Nowicka, Karolina Dzwonek, Agnieszka Zagozdzon, Jakub Golab & Adam Golebiowski. (2020) Discovery and Pharmacokinetics of Sulfamides and Guanidines as Potent Human Arginase 1 Inhibitors. ACS Medicinal Chemistry Letters 11:4, pages 433-438.
Crossref
Gang Yan, Bereket L. Zekarias, Xiaoyu Li, Victor A. Jaffett, Ilia A. Guzei & Jennifer E. Golden. (2020) Divergent 2‐Chloroquinazolin‐4(3 H )‐one Rearrangement: Twisted‐Cyclic Guanidine Formation or Ring‐Fused N ‐Acylguanidines via a Domino Process . Chemistry – A European Journal 26:11, pages 2486-2492.
Crossref
Anna Yu. Spivak, Rezeda R. Khalitova, Darya A. Nedopekina & Rinat R. Gubaidullin. (2020) Antimicrobial properties of amine- and guanidine-functionalized derivatives of betulinic, ursolic and oleanolic acids: Synthesis and structure/activity evaluation. Steroids 154, pages 108530.
Crossref
Angela Mesias-Salazar, Oleksandra S. Trofymchuk, Constantin G. Daniliuc, Antonio Antiñolo, Fernando Carrillo-Hermosilla, Fabiane M. Nachtigall, Leonardo S. Santos & René S. Rojas. (2020) Copper (II) as catalyst for intramolecular cyclization and oxidation of (1,4-phenylene)bisguanidines to benzodiimidazole-diylidenes. Journal of Catalysis 382, pages 150-154.
Crossref
Christopher Llynard D. Ortiz, Gladys C. Completo, Ruel C. Nacario & Ricky B. Nellas. (2019) Potential Inhibitors of Galactofuranosyltransferase 2 (GlfT2): Molecular Docking, 3D-QSAR, and In Silico ADMETox Studies. Scientific Reports 9:1.
Crossref
Aswathy N. Muttathukattil, Sriraksha Srinivasan, Antarip Halder & Govardhan Reddy. (2019) Role of Guanidinium-Carboxylate Ion Interaction in Enzyme Inhibition with Implications for Drug Design. The Journal of Physical Chemistry B 123:44, pages 9302-9311.
Crossref
P. R. Petrova, A. V. Koval’skaya, A. N. Lobov & I. P. Tsypysheva. (2019) Synthesis of Guanidine Derivatives of Methylcytisine. Chemistry of Natural Compounds 55:6, pages 1110-1114.
Crossref
Bo Zhao & Runping Jia. (2019) Preparation of super-hydrophobic films based on waterborne polyurethane and their hydrophobicity characteristics. Progress in Organic Coatings 135, pages 440-448.
Crossref
Haonan Xing, Lin Cheng, Mei Lu, Hui Liu, Lang Lang, Tianzhi Yang, Xiaoyun Zhao, Hui Xu, Li Yang & Pingtian Ding. (2019) A biodegradable poly(amido amine) based on the antimicrobial polymer polyhexamethylene biguanide for efficient and safe gene delivery. Colloids and Surfaces B: Biointerfaces 182, pages 110355.
Crossref
Manchugondanahalli S. Krishna, Zhenzhang Wang, Liangzhen Zheng, Jogesh BowryAlan Ann Lerk Ong, Yuguang Mu, Mookkan Prabakaran & Gang Chen. (2019) Incorporating G-C Pair-Recognizing Guanidinium into PNAs for Sequence and Structure Specific Recognition of dsRNAs over dsDNAs and ssRNAs. Biochemistry 58:36, pages 3777-3788.
Crossref
Ying-Hua Gao, Vanda Lovreković, Akmaral Kussayeva, Dan-Ye Chen, Davor Margetić & Zhi-Long Chen. (2019) The photodynamic activities of dimethyl 131-[2-(guanidinyl)ethylamino] chlorin e6 photosensitizers in A549 tumor. European Journal of Medicinal Chemistry 177, pages 144-152.
Crossref
Keyvan Nosratzadegan, Mohammad Mahdavi, Kamal Ghani & Kazem Barati. (2019) New Energetic Complex of Copper(II) Dinitramide Based Nitrogen‐rich Ligand Aminoguanidine(CH 6 N 4 ): Synthesis, Structural and Energetic Properties . Propellants, Explosives, Pyrotechnics 44:7, pages 830-836.
Crossref
Ting Shu, Tianyu Gan, Peng Bai, Xiaotong Wang, Qi Qian, Hui Zhou, Qi Cheng, Yang Qiu, Lei Yin, Jin Zhong & Xi Zhou. (2019) Ebola virus VP35 has novel NTPase and helicase-like activities. Nucleic Acids Research 47:11, pages 5837-5851.
Crossref
Joydev Hatai & Carsten Schmuck. (2019) Diverse Properties of Guanidiniocarbonyl Pyrrole-Based Molecules: Artificial Analogues of Arginine. Accounts of Chemical Research 52:6, pages 1709-1720.
Crossref
Nor Fadhilah Kamaruzzaman, Li Peng Tan, Ruhil Hayati Hamdan, Siew Shean Choong, Weng Kin Wong, Amanda Jane Gibson, Alexandru Chivu & Maria de Fatima Pina. (2019) Antimicrobial Polymers: The Potential Replacement of Existing Antibiotics?. International Journal of Molecular Sciences 20:11, pages 2747.
Crossref
Rafael Dias do Espírito Santo, Ángela María Arenas Velásquez, Luana Vitorino Gushiken Passianoto, Alex Arbey Lopera Sepulveda, Leandro da Costa Clementino, Renata Pires Assis, Amanda Martins Baviera, Predrag Kalaba, Fábio Neves dos Santos, Marcos Nogueira Éberlin, Gil Valdo José da Silva, Martin Zehl, Gert Lubec, Márcia Aparecida Silva Graminha & Eduardo René Pérez González. (2019) N, N′, N″-trisubstituted guanidines: Synthesis, characterization and evaluation of their leishmanicidal activity. European Journal of Medicinal Chemistry 171, pages 116-128.
Crossref
Haonan Xing, Mei Lu, Tianzhi Yang, Hui Liu, Yanping Sun, Xiaoyun Zhao, Hui Xu, Li Yang & Pingtian Ding. (2019) Structure-function relationships of nonviral gene vectors: Lessons from antimicrobial polymers. Acta Biomaterialia 86, pages 15-40.
Crossref
Sung Min Cho, Hyung Keun Lee, Qing Liu, Ming-Wei Wang & Ho Jeong Kwon. (2018) A Guanidine-Based Synthetic Compound Suppresses Angiogenesis via Inhibition of Acid Ceramidase . ACS Chemical Biology 14:1, pages 11-19.
Crossref
Edeildo F. da Silva-Júnior, Tanja Schirmeister & João X. de Araújo-Júnior. 2019. Discovery and Development of Therapeutics from Natural Products Against Neglected Tropical Diseases. Discovery and Development of Therapeutics from Natural Products Against Neglected Tropical Diseases 165 217 .
Anna Spivak, Rezeda Khalitova, Darya Nedopekina, Lilya Dzhemileva, Milyausha Yunusbaeva, Victor Odinokov, Vladimir D’yakonov & Usein Dzhemilev. (2018) Synthesis and Evaluation of Anticancer Activities of Novel C-28 Guanidine-Functionalized Triterpene Acid Derivatives. Molecules 23:11, pages 3000.
Crossref
Mitsue Fujita & Yoshio Furusho. (2018) Ultrasound-assisted synthesis of substituted guanidines using 1H-pyrazole-1-carboxamidine and S-methylisothiouronium sulfate under solvent-free conditions. Tetrahedron 74:32, pages 4339-4342.
Crossref
András Demjén, Anikó Angyal, János Wölfling, László G. Puskás & Iván Kanizsai. (2018) One-pot synthesis of diverse N , N ′-disubstituted guanidines from N -chlorophthalimide, isocyanides and amines via N -phthaloyl-guanidines . Organic & Biomolecular Chemistry 16:12, pages 2143-2149.
Crossref
Teng-Feng Li, Myra Hosmillo, Hella Schwanke, Ting Shu, Zhaowei Wang, Lei Yin, Stephen Curry, Ian G. Goodfellow & Xi Zhou. (2018) Human Norovirus NS3 Has RNA Helicase and Chaperoning Activities. Journal of Virology 92:5.
Crossref
Henrique Esteves, Tiago Oliveira Brito, Renato Ribeiro-Viana, Ângelo de Fátima & Fernando MacedoJr.Jr.. (2017) Tert -butyl hydroperoxide-promoted guanylation of amines with benzoylthioureas: Mechanistic insights by HRMS and 1 H NMR . Journal of Physical Organic Chemistry 30:12, pages e3698.
Crossref
R. Gul, A. Badshah, A. Ali Altaf, S. Tabassum & M. Zia. (2017) New ferrocenyl guanidines as potent antioxidants, protein kinase inhibitors and cytotoxic agents against human leukemia THP-1 cell line. Russian Journal of General Chemistry 87:11, pages 2684-2689.
Crossref
Gabriel Glotz, René Lebl, Doris Dallinger & C. Oliver Kappe. (2017) Integration of Bromine and Cyanogen Bromide Generators for the Continuous-Flow Synthesis of Cyclic Guanidines. Angewandte Chemie International Edition 56:44, pages 13786-13789.
Crossref
Gabriel Glotz, René Lebl, Doris Dallinger & C. Oliver Kappe. (2017) Integration of Bromine and Cyanogen Bromide Generators for the Continuous‐Flow Synthesis of Cyclic Guanidines. Angewandte Chemie 129:44, pages 13974-13977.
Crossref
Sirilak Wangngae, Mookda Pattarawarapan & Wong Phakhodee. (2017) Ph 3 P/I 2 -Mediated Synthesis of N,N ′ ,N ″-Substituted Guanidines and 2-Iminoimidazolin-4-ones from Aryl Isothiocyanates . The Journal of Organic Chemistry 82:19, pages 10331-10340.
Crossref
Irena Matulková, Hana Charvátová, Ivana Císařová & Petr Štěpnička. (2017) The crystal structure of the inner salt of 2-[(aminoiminomethyl)amino]ethylcarbamic acid [systematic name: (2-((diaminomethylene)ammonio)ethyl)carbamate], C 4 H 10 N 4 O 2 . Zeitschrift für Kristallographie - New Crystal Structures 232:4, pages 685-687.
Crossref
Aleksej Turočkin, William Raven & Philipp Selig. (2017) Synthesis of Bicyclic and Tricyclic Chiral Guanidinium Salts by an Intramolecular Alkylation Approach. European Journal of Organic Chemistry 2017:2, pages 296-305.
Crossref
A. V. Lysytsya, Y. M. Mandygra & A. A. Vysotsky. (2017) Future directions for use guanidine derivatives in veterinary medicine and agricultural production (review). Bulletin "Veterinary biotechnology" 30, pages 133-145.
Crossref
Cai Li, Kwok-Wa Ip, Wai-Lun Man, Dan Song, Ming-Liang He, Shek-Man Yiu, Tai-Chu Lau & Guangyu Zhu. (2017) Cytotoxic (salen)ruthenium( iii ) anticancer complexes exhibit different modes of cell death directed by axial ligands . Chemical Science 8:10, pages 6865-6870.
Crossref
Ligia F. Martins, Juliana T. Mesquita, Erika G. Pinto, Thais A. Costa-Silva, Samanta E. T. Borborema, Andres J. Galisteo Junior, Bruno J. Neves, Carolina H. Andrade, Zainab Al Shuhaib, Elliot L. Bennett, Gregory P. Black, Philip M. Harper, Daniel M. Evans, Hisham S. Fituri, John P. Leyland, Claire Martin, Terence D. Roberts, Andrew J. Thornhill, Stephen A. Vale, Andrew Howard-Jones, Dafydd A. Thomas, Harri L. Williams, Larry E. Overman, Roberto G. S. Berlinck, Patrick J. Murphy & Andre G. Tempone. (2016) Analogues of Marine Guanidine Alkaloids Are in Vitro Effective against Trypanosoma cruzi and Selectively Eliminate Leishmania ( L .) infantum Intracellular Amastigotes . Journal of Natural Products 79:9, pages 2202-2210.
Crossref
Yurii V. Koshchienko, Tatyana A. Kuz’menko, Anatolii S. Morkovnik, Mikhail A. Kiskin & Grigorii G. Alexandrov. (2016) Unexpected domino reaction of 3-alkyl-1,2,4-triazolo[1,5-a]benzimidazoles with butylmagnesium bromide leading to benzimidazolyl guanidines. Mendeleev Communications 26:4, pages 320-322.
Crossref
Simon Pape, Pablo Wessig & Heiko Brunner. (2016) Iron Trichloride and Air Mediated Guanylation of Acylthioureas. An Ecological Route to Acylguanidines: Scope and Mechanistic Insights. The Journal of Organic Chemistry 81:11, pages 4701-4712.
Crossref
Rebecca J. Abraham, Andrew J. Stevens, Kelly A. Young, Cecilia Russell, Anastasia Qvist, Manouchehr Khazandi, Hui San Wong, Sam Abraham, Abiodun D. Ogunniyi, Stephen W. Page, Ryan O’Handley, Adam McCluskey & Darren J. Trott. (2016) Robenidine Analogues as Gram-Positive Antibacterial Agents. Journal of Medicinal Chemistry 59:5, pages 2126-2138.
Crossref
Mookda Pattarawarapan, Subin Jaita, Sirilak Wangngae & Wong Phakhodee. (2016) Ultrasound-assisted synthesis of substituted guanidines from thioureas. Tetrahedron Letters 57:12, pages 1354-1358.
Crossref
Kenji Mishiro, Fanghao Hu, Daniel W. Paley, Wei Min & Tristan H. Lambert. (2016) Macrosteres: The Deltic Guanidin­ium Ion. European Journal of Organic Chemistry 2016:9, pages 1655-1659.
Crossref
Andrés G. Santana, Sandra G. Zárate, Juan Luis Asensio, Julia Revuelta & Agatha Bastida. (2016) Selective modification of the 3′′-amino group of kanamycin prevents significant loss of activity in resistant bacterial strains. Organic & Biomolecular Chemistry 14:2, pages 516-525.
Crossref
Tayyebeh Panahi, Douglas J. Weaver, John D. Lamb & Roger G. Harrison. (2016) A new approach for trace analysis of guanidine compounds in surface water with resorcinarene-based ion chromatography columns. The Analyst 141:3, pages 939-946.
Crossref
Henrique Esteves, Ângelo de Fátima, Rosane de P. Castro, José R. Sabino, Fernando MacedoJr.Jr. & Tiago Oliveira Brito. (2015) A simple one-pot methodology for the synthesis of substituted benzoylguanidines from benzoylthioureas using tert-butyl hydroperoxide. Tetrahedron Letters 56:49, pages 6872-6874.
Crossref
Yang Yang, Zhijian Xu, Zhengyan Zhang, Zhuo Yang, Yingtao Liu, Jinan Wang, Tingting Cai, Shujin Li, Kaixian Chen, Jiye Shi & Weiliang Zhu. (2015) Like-Charge Guanidinium Pairing between Ligand and Receptor: An Unusual Interaction for Drug Discovery and Design?. The Journal of Physical Chemistry B 119:36, pages 11988-11997.
Crossref
Yuanchao Xie, Dongqing Xu, Junhua Wang, Weidong Xiao & Wenfang Xu. (2014) Synthesis of cis-4-guanidino-l-proline and 1-carbamimidoyl-l-proline derivatives as influenza neuraminidase inhibitors. Medicinal Chemistry Research 24:3, pages 1013-1017.
Crossref
Simon Pape, Pablo Wessig & Heiko Brunner. (2015) A new and environmentally benign synthesis of aroylguanidines using iron trichloride. RSC Advances 5:123, pages 101408-101411.
Crossref
Julian W. Shaw, David H. Grayson & Isabel Rozas. 2017. Guanidines as Reagents and Catalysts I. Guanidines as Reagents and Catalysts I 1 51 .
Priya Saxena, Natesan Thirupathi & Munirathinam Nethaji. (2014) Depalladation of Neutral Monoalkyne- and Dialkyne-Inserted Palladacycles and Alkyne Insertion/Depalladation Reactions of Cationic Palladacycles Derived from N , N ′, N ″-Triarylguanidines as Facile Routes for Guanidine-Containing Heterocycles/Carbocycles: Synthetic, Structural, and Mechanistic Aspects . Organometallics 33:19, pages 5554-5565.
Crossref
Rukhsana Gul, Muhammad Khawar Rauf, Amin Badshah, Syed Sikander Azam, Muhammad Nawaz Tahir & Azim Khan. (2014) Ferrocene-based guanidine derivatives: In vitro antimicrobial, DNA binding and docking supported urease inhibition studies. European Journal of Medicinal Chemistry 85, pages 438-449.
Crossref
Konstantin Andreev, Christopher Bianchi, Jonas S. Laursen, Linda Citterio, Line Hein-Kristensen, Lone Gram, Ivan Kuzmenko, Christian A. Olsen & David Gidalevitz. (2014) Guanidino groups greatly enhance the action of antimicrobial peptidomimetics against bacterial cytoplasmic membranes. Biochimica et Biophysica Acta (BBA) - Biomembranes 1838:10, pages 2492-2502.
Crossref
Fouad H. Darras, Beata Kling, Edgar Sawatzky, Jörg Heilmann & Michael Decker. (2014) Cyclic acyl guanidines bearing carbamate moieties allow potent and dirigible cholinesterase inhibition of either acetyl- or butyrylcholinesterase. Bioorganic & Medicinal Chemistry 22:17, pages 5020-5034.
Crossref
Ahmed M. Soliman, Shaaban K. Mohamed, Mahmoud. Abd El Aleem. Ali. Ali. El-Remaily & H. Abdel-Ghany. (2014) Synthesis of Novel Modified Guanidines: Reaction of Dicyandiamide with Amino Acids, Amides, and Amines in Aqueous Medium. Journal of Heterocyclic Chemistry 51:5, pages 1322-1326.
Crossref
Grigor'eva Maria Nikolaevna, Stel'makh Sergey Aleksandrovich, Astakhova Svetlana Aleksandrovna, Tsenter Irina Mihaylovna, Bazaron Larisa Ulzitovna, Batoev Valeriy Babudorjievich & Mognonov Dmitry Markovich. (2014) Biocidal action of copolymers based on aliphatic diamines and guanidine hydrochloride. Journal of Applied Polymer Science 131:11, pages n/a-n/a.
Crossref
Johannes Christian Haenle, Manuel M. Neidhardt, Stuart Beardsworth, Jochen Kirres, Angelika Baro & Sabine Laschat. (2014) Cyanobiphenyl versus Alkoxybiphenyl: Which Mesogenic Unit Governs the Mesomorphic Properties of Guanidinium Ionic Liquid Crystals?. Australian Journal of Chemistry 67:7, pages 1088.
Crossref
Niko Fischer, Manuel Joas, Thomas M. Klapötke & Jörg Stierstorfer. (2013) Transition Metal Complexes of 3-Amino-1-nitroguanidine as Laser Ignitible Primary Explosives: Structures and Properties. Inorganic Chemistry 52:23, pages 13791-13802.
Crossref
Rakesh Kumar, Denis S. Ermolat’ev & Erik V. Van der Eycken. (2013) Synthesis of Differentially Substituted 2-Aminoimidazolidines via a Microwave-Assisted Tandem Staudinger/Aza-Wittig Cyclization. The Journal of Organic Chemistry 78:11, pages 5737-5743.
Crossref
Claudia Mattheis, Hui Wang, Claus Meister & Seema Agarwal. (2013) Effect of Guanidinylation on the Properties of Poly(2-aminoethylmethacrylate)-Based Antibacterial Materials. Macromolecular Bioscience 13:2, pages 242-255.
Crossref
Adam J. Rosenberg, Theresa M. Williams, Abraham J. Jordan & Daniel A. Clark. (2013) Synthesis of 2-amino-imidazo[4,5-b]pyridines. Organic & Biomolecular Chemistry 11:18, pages 3064.
Crossref
Claudia Mattheis, Hui Wang, Martin C. Schwarzer, Gernot Frenking & Seema Agarwal. (2013) Exploring suitable oligoamines for phantom ring-closing condensation polymerization with guanidine hydrochloride. Polym. Chem. 4:3, pages 707-716.
Crossref
Tjøstil Vlaar, Razvan C. Cioc, Pieter Mampuys, Bert U. W. Maes, Romano V. A. Orru & Eelco Ruijter. (2012) Sustainable Synthesis of Diverse Privileged Heterocycles by Palladium‐Catalyzed Aerobic Oxidative Isocyanide Insertion. Angewandte Chemie International Edition 51:52, pages 13058-13061.
Crossref
Tjøstil Vlaar, Razvan C. Cioc, Pieter Mampuys, Bert U. W. Maes, Romano V. A. Orru & Eelco Ruijter. (2012) Sustainable Synthesis of Diverse Privileged Heterocycles by Palladium‐Catalyzed Aerobic Oxidative Isocyanide Insertion. Angewandte Chemie 124:52, pages 13235-13238.
Crossref
Jana Plsikova, Ladislav Janovec, Jan Koval, Jan Ungvarsky, Jaromir Mikes, Rastislav Jendzelovsky, Peter Fedorocko, Jan Imrich, Pavol Kristian, Jana Kasparkova, Viktor Brabec & Maria Kozurkova. (2012) 3,6-Bis(3-alkylguanidino)acridines as DNA-intercalating antitumor agents. European Journal of Medicinal Chemistry 57, pages 283-295.
Crossref
Najoua Derbel, Igor Clarot, Maxime Mourer, Jean-Bernard Regnouf-de-Vains & Manuel F. Ruiz-López. (2012) Intramolecular Interactions versus Hydration Effects on p -Guanidinoethyl-phenol Structure and p K a Values . The Journal of Physical Chemistry A 116:37, pages 9404-9411.
Crossref
Paula López-Senín, Gerard Artigas & Vicente Marchán. (2012) Exploring the effect of aminoglycoside guanidinylation on ligands for Tau exon 10 splicing regulatory element RNA. Organic & Biomolecular Chemistry 10:46, pages 9243.
Crossref
Zhongxin Zhou, Dafu Wei, Yong Guan, Anna Zheng & Jian-Jiang Zhong. (2011) Extensive in vitro activity of guanidine hydrochloride polymer analogs against antibiotics-resistant clinically isolated strains. Materials Science and Engineering: C 31:8, pages 1836-1843.
Crossref
Zhongxin Zhou, Anna Zheng & Jianjiang Zhong. (2011) Interactions of biocidal guanidine hydrochloride polymer analogs with model membranes: a comparative biophysical study. Acta Biochimica et Biophysica Sinica 43:9, pages 729-737.
Crossref
Jos H.M. Lange, Stefan Verhoog, Hans J. Sanders, Arnold van Loevezijn & Chris G. Kruse. (2011) A novel atom-efficient, one-pot synthesis of sulfonylguanidines and sulfamoylguanidines. Tetrahedron Letters 52:25, pages 3198-3200.
Crossref
Jos H.M. Lange, Hans J. Sanders & Jeroen van Rheenen. (2011) An expedient atom-efficient synthesis of the cannabinoid CB1 receptor inverse agonist ibipinabant. Tetrahedron Letters 52:12, pages 1303-1305.
Crossref
Roland Kleinmaier & Ruth M. Gschwind. (2010) Chemical shift assignment and conformational analysis of monoalkylated acylguanidines. Magnetic Resonance in Chemistry 48:9, pages 678-684.
Crossref
Roland Kleinmaier, Max Keller, Patrick Igel, Armin Buschauer & Ruth M. Gschwind. (2010) Conformations, Conformational Preferences, and Conformational Exchange of N′-Substituted N -Acylguanidines: Intermolecular Interactions Hold the Key . Journal of the American Chemical Society 132:32, pages 11223-11233.
Crossref
Roberto G. S. Berlinck, Antonio Carlos B. Burtoloso, Amaro E. Trindade-Silva, Stelamar Romminger, Raquel P. Morais, Karin Bandeira & Carolina M. Mizuno. (2010) The chemistry and biology of organic guanidine derivatives. Natural Product Reports 27:12, pages 1871.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.