Citations (117)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (37)
Claudiu T. Supuran. (2020) Exploring the multiple binding modes of inhibitors to carbonic anhydrases for novel drug discovery. Expert Opinion on Drug Discovery 15:6, pages 671-686.
Read now
Read now
Jeremie Brichet, Rodrigo Arancibia, Emanuela Berrino & Claudiu T. Supuran. (2020) Bioorganometallic derivatives of 4-hydrazino-benzenesulphonamide as carbonic anhydrase inhibitors: synthesis, characterisation and biological evaluation. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 622-628.
Read now
Read now
Alessio Nocentini & Claudiu T. Supuran. (2019) Advances in the structural annotation of human carbonic anhydrases and impact on future drug discovery. Expert Opinion on Drug Discovery 14:11, pages 1175-1197.
Read now
Read now
Claudiu T. Supuran, Abdulmalik Saleh Alfawaz Altamimi & Fabrizio Carta. (2019) Carbonic anhydrase inhibition and the management of glaucoma: a literature and patent review 2013-2019. Expert Opinion on Therapeutic Patents 29:10, pages 781-792.
Read now
Read now
Claudiu T Supuran. (2019) The management of glaucoma and macular degeneration. Expert Opinion on Therapeutic Patents 29:10, pages 745-747.
Read now
Read now
Claudiu T. Supuran. (2019) Agents for the prevention and treatment of age-related macular degeneration and macular edema: a literature and patent review. Expert Opinion on Therapeutic Patents 29:10, pages 761-767.
Read now
Read now
Silvia Bua & Claudiu T Supuran. (2019) Diagnostic markers for glaucoma: a patent and literature review (2013-2019). Expert Opinion on Therapeutic Patents 29:10, pages 829-839.
Read now
Read now
Andrea Angeli & Claudiu T Supuran. (2019) Prostaglandin receptor agonists as antiglaucoma agents (a patent review 2013 – 2018). Expert Opinion on Therapeutic Patents 29:10, pages 793-803.
Read now
Read now
Paolo Guglielmi, Simone Carradori, Cristina Campestre & Giovanna Poce. (2019) Novel therapies for glaucoma: a patent review (2013-2019). Expert Opinion on Therapeutic Patents 29:10, pages 769-780.
Read now
Read now
Sonia Del Prete, Rosa Merlo, Anna Valenti, Rosanna Mattossovich, Mosè Rossi, Vincenzo Carginale, Claudiu T. Supuran, Giuseppe Perugino & Clemente Capasso. (2019) Thermostability enhancement of the α-carbonic anhydrase from Sulfurihydrogenibium yellowstonense by using the anchoring-and-self-labelling-protein-tag system (ASL). Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 946-954.
Read now
Read now
Claudiu T. Supuran. (2018) Carbonic anhydrase inhibitors as emerging agents for the treatment and imaging of hypoxic tumors. Expert Opinion on Investigational Drugs 27:12, pages 963-970.
Read now
Read now
Claudiu T. Supuran. (2018) Carbonic anhydrase inhibitors and their potential in a range of therapeutic areas. Expert Opinion on Therapeutic Patents 28:10, pages 709-712.
Read now
Read now
Claudiu T. Supuran. (2018) Applications of carbonic anhydrases inhibitors in renal and central nervous system diseases. Expert Opinion on Therapeutic Patents 28:10, pages 713-721.
Read now
Read now
Claudiu T. Supuran & Clemente Capasso. (2018) Biomedical applications of prokaryotic carbonic anhydrases. Expert Opinion on Therapeutic Patents 28:10, pages 745-754.
Read now
Read now
Claudiu T. Supuran. (2018) Carbon- versus sulphur-based zinc binding groups for carbonic anhydrase inhibitors?. Journal of Enzyme Inhibition and Medicinal Chemistry 33:1, pages 485-495.
Read now
Read now
Claudiu T. Supuran. (2017) Advances in structure-based drug discovery of carbonic anhydrase inhibitors. Expert Opinion on Drug Discovery 12:1, pages 61-88.
Read now
Read now
Erol Licsandru, Muhammet Tanc, Istvan Kocsis, Mihail Barboiu & Claudiu T. Supuran. (2017) A class of carbonic anhydrase I – selective activators. Journal of Enzyme Inhibition and Medicinal Chemistry 32:1, pages 37-46.
Read now
Read now
F. Zehra Küçükbay, Hasan Küçükbay, Muhammet Tanc & Claudiu T. Supuran. (2016) Synthesis and carbonic anhydrase I, II, IV and XII inhibitory properties of N-protected amino acid – sulfonamide conjugates. Journal of Enzyme Inhibition and Medicinal Chemistry 31:6, pages 1476-1483.
Read now
Read now
Ozen Ozensoy Guler, Clemente Capasso & Claudiu T. Supuran. (2016) A magnificent enzyme superfamily: carbonic anhydrases, their purification and characterization. Journal of Enzyme Inhibition and Medicinal Chemistry 31:5, pages 689-694.
Read now
Read now
Claudiu T. Supuran. (2016) Carbonic anhydrase inhibition and the management of neuropathic pain. Expert Review of Neurotherapeutics 16:8, pages 961-968.
Read now
Read now
Claudiu T. Supuran. (2016) How many carbonic anhydrase inhibition mechanisms exist?. Journal of Enzyme Inhibition and Medicinal Chemistry 31:3, pages 345-360.
Read now
Read now
Claudiu T. Supuran. (2016) Drug interaction considerations in the therapeutic use of carbonic anhydrase inhibitors. Expert Opinion on Drug Metabolism & Toxicology 12:4, pages 423-431.
Read now
Read now
Murat Bozdag, Fabrizio Carta, Daniela Vullo, Semra Isik, Zeid AlOthman, Sameh M. Osman, Andrea Scozzafava & Claudiu T. Supuran. (2016) Dithiocarbamates with potent inhibitory activity against the Saccharomyces cerevisiae β-carbonic anhydrase. Journal of Enzyme Inhibition and Medicinal Chemistry 31:1, pages 132-136.
Read now
Read now
Namrata Singasane, Prashant S. Kharkar, Mariangela Ceruso, Claudiu T. Supuran & Mrunmayee P. Toraskar. (2015) Inhibition of carbonic anhydrase isoforms I, II, IX and XII with Schiff’s bases incorporating iminoureido moieties. Journal of Enzyme Inhibition and Medicinal Chemistry 30:6, pages 901-907.
Read now
Read now
Daniela Vullo, Semra Isik, Murat Bozdag, Fabrizio Carta & Claudiu T. Supuran. (2015) 7-Amino-3,4-dihydro-1H-quinolin-2-one, a compound similar to the substituted coumarins, inhibits α-carbonic anhydrases without hydrolysis of the lactam ring. Journal of Enzyme Inhibition and Medicinal Chemistry 30:5, pages 773-777.
Read now
Read now
Claudiu T Supuran. (2015) Acetazolamide for the treatment of idiopathic intracranial hypertension. Expert Review of Neurotherapeutics 15:8, pages 851-856.
Read now
Read now
Ahmed M. Alafeefy, Hatem A. Abdel-Aziz, Daniela Vullo, Abdul-Malek S. Al-Tamimi, Amani S. Awaad, Menshawy A. Mohamed, Clemente Capasso & Claudiu T. Supuran. (2015) Inhibition of human carbonic anhydrase isozymes I, II, IX and XII with a new series of sulfonamides incorporating aroylhydrazone-, [1,2,4]triazolo[3,4-b][1,3,4]thiadiazinyl- or 2-(cyanophenylmethylene)-1,3,4-thiadiazol-3(2H)-yl moieties. Journal of Enzyme Inhibition and Medicinal Chemistry 30:1, pages 52-56.
Read now
Read now
Yangbo Feng & Philip V LoGrasso. (2014) Rho kinase inhibitors: a patent review (2012 – 2013). Expert Opinion on Therapeutic Patents 24:3, pages 295-307.
Read now
Read now
Asta Zubrienė, Edita Čapkauskaitė, Joana Gylytė, Miglė Kišonaitė, Sigitas Tumkevičius & Daumantas Matulis. (2014) Benzenesulfonamides with benzimidazole moieties as inhibitors of carbonic anhydrases I, II, VII, XII and XIII. Journal of Enzyme Inhibition and Medicinal Chemistry 29:1, pages 124-131.
Read now
Read now
Giuseppina De Simone, Vincenzo Alterio & Claudiu T Supuran. (2013) Exploiting the hydrophobic and hydrophilic binding sites for designing carbonic anhydrase inhibitors. Expert Opinion on Drug Discovery 8:7, pages 793-810.
Read now
Read now
Emanuela Masini, Fabrizio Carta, Andrea Scozzafava & Claudiu T Supuran. (2013) Antiglaucoma carbonic anhydrase inhibitors: a patent review. Expert Opinion on Therapeutic Patents 23:6, pages 705-716.
Read now
Read now
Fabrizio Carta & Claudiu T Supuran. (2013) Diuretics with carbonic anhydrase inhibitory action: a patent and literature review (2005 – 2013). Expert Opinion on Therapeutic Patents 23:6, pages 681-691.
Read now
Read now
Clemente Capasso & Claudiu T Supuran. (2013) Anti-infective carbonic anhydrase inhibitors: a patent and literature review. Expert Opinion on Therapeutic Patents 23:6, pages 693-704.
Read now
Read now
Claudiu T. Supuran. (2012) Structure-based drug discovery of carbonic anhydrase inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 27:6, pages 759-772.
Read now
Read now
Almudena Crooke, Fernando Huete-Toral, Alejandro Martínez-Águila, Basilio Colligris & Jesus Pintor. (2012) Ocular disorders and the utility of animal models in the discovery of melatoninergic drugs with therapeutic potential. Expert Opinion on Drug Discovery 7:10, pages 989-1001.
Read now
Read now
Claudiu T Supuran. (2012) Amide derivatives of benzene-sulfonanilide, pharmaceutical composition thereof and method for cancer treatment using the same (US20120095092). Expert Opinion on Therapeutic Patents 22:10, pages 1251-1255.
Read now
Read now
Fabrizio Carta, Andrea Scozzafava & Claudiu T Supuran. (2012) Sulfonamides: a patent review (2008 – 2012). Expert Opinion on Therapeutic Patents 22:7, pages 747-758.
Read now
Read now
Articles from other publishers (80)
Nagihan Uğurlu, Ebru Erdal, Soheil Malekghasemi & Murat Demirbilek. (2023) Effectiveness of carbonic anhydrase inhibitor loaded nanoparticles in the treatment of diabetic retinopathy. Biomedical Physics & Engineering Express 10:1, pages 015002.
Crossref
Crossref
Prashant Sharma, Abhinoy Kishore, Indranil De, Swarnima Negi, Gulshan Kumar, Sahil Bhardwaj & Manish Singh. (2023) Mitigating neuroinflammation in Parkinson's disease: Exploring the role of proinflammatory cytokines and the potential of phytochemicals as natural therapeutics. Neurochemistry International, pages 105604.
Crossref
Crossref
Claudiu T. Supuran. (2023) A simple yet multifaceted 90 years old, evergreen enzyme: Carbonic anhydrase, its inhibition and activation. Bioorganic & Medicinal Chemistry Letters 93, pages 129411.
Crossref
Crossref
A. L. Khokhlov, A. A. Shetnev, M. K. Korsakov, V. N. Fedorov, A. N. Tyushina, N. N. Volkhin & V. P. Vdovichenko. (2023) Pharmacological Properties of Sulfonamide Derivatives, New Inhibitors of Carbonic Anhydrase. Bulletin of Experimental Biology and Medicine 175:2, pages 205-209.
Crossref
Crossref
Büşra ÇALIŞKAN, Mine AKSOY, Muhammet Serhat ÖZASLAN & İlknur AKYOL SALMAN. (2023) Investigation of Some Metabolic Enzyme Activities in Samples of Serum and Humor Aqueous of Cataract Cases with Pseudoexfoliation Syndrome. Türk Doğa ve Fen Dergisi 12:1, pages 163-170.
Crossref
Crossref
Davide Moi, Serena Vittorio, Andrea Angeli, Gianfranco Balboni, Claudiu T. Supuran & Valentina Onnis. (2022) Investigation on Hydrazonobenzenesulfonamides as Human Carbonic Anhydrase I, II, IX and XII Inhibitors. Molecules 28:1, pages 91.
Crossref
Crossref
Valentina Gocić, Ana Marković & Jelena Lazarević. (2022) The potential of chalcone derivatives as human carbonic anhydrase inhibitors in the therapy of glaucoma. Medicinal Chemistry Research 31:12, pages 2103-2118.
Crossref
Crossref
Pınar Eraslan‐Elma, Atilla Akdemir, Emanuela Berrino, Murat Bozdağ, Claudiu T. Supuran & Nilgün Karalı. (2022)
New 1
H
‐indole‐2,3‐dione 3‐thiosemicarbazones with 3‐sulfamoylphenyl moiety as selective carbonic anhydrase inhibitors
. Archiv der Pharmazie 355:8.
Crossref
Crossref
Benas Balandis, Tomas Šimkūnas, Vaida Paketurytė-Latvė, Vilma Michailovienė, Aurelija Mickevičiūtė, Elena Manakova, Saulius Gražulis, Sergey Belyakov, Visvaldas Kairys, Vytautas Mickevičius, Asta Zubrienė & Daumantas Matulis. (2022) Beta and Gamma Amino Acid-Substituted Benzenesulfonamides as Inhibitors of Human Carbonic Anhydrases. Pharmaceuticals 15:4, pages 477.
Crossref
Crossref
Pengcheng Lv, Yinyi Cai, Jiayi Luo & Kun Chen. (2022) Recent Advances in the Design and Synthesis of Small Molecule Carbonic
Anhydrase IX Inhibitors. Current Topics in Medicinal Chemistry 22:7, pages 550-560.
Crossref
Crossref
Marko M. Popovic, Matthew B. Schlenker, Deva Thiruchelvam & Donald A. Redelmeier. (2022) Serious Adverse Events of Oral and Topical Carbonic Anhydrase Inhibitors. JAMA Ophthalmology 140:3, pages 235.
Crossref
Crossref
P.A. Bezdetko. (2022) Again about carbonic anhydrase inhibitors: modern aspects of the use of ICA in ophthalmology. Archive of Ukrainian Ophthalmology 9:2, pages 64-71.
Crossref
Crossref
Zhuang Hou, Qiang Cai & Mao-sheng Cheng. (2021) Novel carbohydrate-based sulfonamide derivatives as selective carbonic anhydrase II inhibitors: Synthesis, biological and molecular docking analysis. Bioorganic & Medicinal Chemistry Letters 51, pages 128291.
Crossref
Crossref
Phatsawee Jansook, Hay Marn Hnin, Thorsteinn Loftsson & Einar Stefánsson. (2021) Cyclodextrin-based formulation of carbonic anhydrase inhibitors for ocular delivery – A review. International Journal of Pharmaceutics 606, pages 120955.
Crossref
Crossref
Claudiu T. Supuran. (2021) Emerging role of carbonic anhydrase inhibitors. Clinical Science 135:10, pages 1233-1249.
Crossref
Crossref
Chandra Bhushan Mishra, Shikha Kumari, Andrea Angeli, Silvia Bua, Raj Kumar Mongre, Manisha Tiwari & Claudiu T. Supuran. (2021) Discovery of Potent Carbonic Anhydrase Inhibitors as Effective Anticonvulsant Agents: Drug Design, Synthesis, and In Vitro and In Vivo Investigations. Journal of Medicinal Chemistry 64:6, pages 3100-3114.
Crossref
Crossref
Jing Zhang, Zhi-Peng Lai, Pei Chen, Yang Ying, Jing Zhuang & Ke-Ming Yu. (2021) Glycogen synthase kinase-3β inhibitor SB216763 promotes DNA repair in ischemic retinal neurons. Neural Regeneration Research 16:2, pages 394.
Crossref
Crossref
Claudiu T. Supuran. 2021. New Trends in Macromolecular and Supramolecular Chemistry for Biological Applications. New Trends in Macromolecular and Supramolecular Chemistry for Biological Applications
115
131
.
N. I. Kurysheva. (2020) Carbonic Anhydrase Inhibitors in the Treatment of Glaucoma. Review. Part I. Ophthalmology in Russia 17:3s, pages 542-549.
Crossref
Crossref
Soumajit Ghorai, Sravani Pulya, Kalyan Ghosh, Parthasarathi Panda, Balaram Ghosh & Shovanlal Gayen. (2020) Structure-activity relationship of human carbonic anhydrase-II inhibitors: Detailed insight for future development as anti-glaucoma agents. Bioorganic Chemistry 95, pages 103557.
Crossref
Crossref
Claudiu T. Supuran & Clemente Capasso. 2020. Physiological and Biotechnological Aspects of Extremophiles. Physiological and Biotechnological Aspects of Extremophiles
295
306
.
Liliana Mititelu-Tarțău, Beatrice Rozalina Buca, Paula Alina Fotache, Maria Bogdan, Eliza Grațiela Popa & Carmen Gafițanu. (2019) New insights in the pharmacotherapy of glaucoma. Farmacist.ro 5:1, pages 20-23.
Crossref
Crossref
Clemente Capasso & Mihail Barboiu. 2019. Carbonic Anhydrases. Carbonic Anhydrases
495
514
.
Emanuela Berrino & Fabrizio Carta. 2019. Carbonic Anhydrases. Carbonic Anhydrases
311
329
.
Silvia Bua, Alessio Nocentini & Claudiu T. Supuran. 2019. Carbonic Anhydrases. Carbonic Anhydrases
287
309
.
Emanuela Masini, Silvia Sgambellone & Laura Lucarini. 2019. Carbonic Anhydrases. Carbonic Anhydrases
269
285
.
Chandra Bhushan Mishra, Shikha Kumari, Andrea Angeli, Silvia Bua, Martina Buonanno, Simona Maria Monti, Manisha Tiwari & Claudiu T. Supuran. (2018) Discovery of potent anti-convulsant carbonic anhydrase inhibitors: Design, synthesis, in vitro and in vivo appraisal. European Journal of Medicinal Chemistry 156, pages 430-443.
Crossref
Crossref
Alessio Nocentini, Mariangela Ceruso, Silvia Bua, Carrie L. Lomelino, Jacob T. Andring, Robert McKenna, Cecilia Lanzi, Silvia Sgambellone, Riccardo Pecori, Rosanna Matucci, Luca Filippi, Paola Gratteri, Fabrizio Carta, Emanuela Masini, Silvia Selleri & Claudiu T. Supuran. (2018) Discovery of β-Adrenergic Receptors Blocker–Carbonic Anhydrase Inhibitor Hybrids for Multitargeted Antiglaucoma Therapy. Journal of Medicinal Chemistry 61:12, pages 5380-5394.
Crossref
Crossref
Srinivas Angapelly, Andrea Angeli, Arbaj Jabbar Khan, P. V. Sri Ramya, Claudiu T. Supuran & Mohammed Arifuddin. (2018) Synthesis and Biological Evaluation of 4-Sulfamoylphenyl/Sulfocoumarin Carboxamides as Selective Inhibitors of Carbonic Anhydrase Isoforms hCA II, IX, and XII. ChemMedChem 13:12, pages 1165-1171.
Crossref
Crossref
Chandra Bhushan Mishra, Shikha Kumari, Andrea Angeli, Silvia Bua, Manisha Tiwari & Claudiu T. Supuran. (2018) Discovery of Benzenesulfonamide Derivatives as Carbonic Anhydrase Inhibitors with Effective Anticonvulsant Action: Design, Synthesis, and Pharmacological Evaluation. Journal of Medicinal Chemistry 61:7, pages 3151-3165.
Crossref
Crossref
Srinivas Angapelly, P.V. Sri Ramya, Andrea Angeli, Sonia Del Prete, Clemente Capasso, Mohammed Arifuddin & Claudiu T. Supuran. (2017) Development of sulfonamides incorporating phenylacrylamido functionalities as carbonic anhydrase isoforms I, II, IX and XII inhibitors. Bioorganic & Medicinal Chemistry 25:20, pages 5726-5732.
Crossref
Crossref
Marta Ferraroni, Laura Lucarini, Emanuela Masini, Mikhail Korsakov, Andrea Scozzafava, Claudiu T. Supuran & Mikhail Krasavin. (2017) 1,3-Oxazole-based selective picomolar inhibitors of cytosolic human carbonic anhydrase II alleviate ocular hypertension in rabbits: Potency is supported by X-ray crystallography of two leads. Bioorganic & Medicinal Chemistry 25:17, pages 4560-4565.
Crossref
Crossref
Chun Gwon Park, Young Kook Kim, Se-Na Kim, Seung Ho Lee, Beom Kang Huh, Min-A Park, Hyein Won, Ki Ho Park & Young Bin Choy. (2017) Enhanced ocular efficacy of topically-delivered dorzolamide with nanostructured mucoadhesive microparticles. International Journal of Pharmaceutics 522:1-2, pages 66-73.
Crossref
Crossref
Chandra Bhushan Mishra, Shikha Kumari, Andrea Angeli, Simona Maria Monti, Martina Buonanno, Manisha Tiwari & Claudiu T. Supuran. (2017) Discovery of Benzenesulfonamides with Potent Human Carbonic Anhydrase Inhibitory and Effective Anticonvulsant Action: Design, Synthesis, and Pharmacological Assessment. Journal of Medicinal Chemistry 60:6, pages 2456-2469.
Crossref
Crossref
Yann Le Duc, Erol Licsandru, Daniela Vullo, Mihail Barboiu & Claudiu T. Supuran. (2017) Carbonic anhydrases activation with 3-amino-1H-1,2,4-triazole-1-carboxamides: Discovery of subnanomolar isoform II activators. Bioorganic & Medicinal Chemistry 25:5, pages 1681-1686.
Crossref
Crossref
Srinivas Angapelly, P.V. Sri Ramya, Andrea Angeli, Simona Maria Monti, Martina Buonanno, Mallika Alvala, Cladiu T. Supuran & Mohammed Arifuddin. (2017) Discovery of 4-sulfamoyl-phenyl-β-lactams as a new class of potent carbonic anhydrase isoforms I, II, IV and VII inhibitors: The first example of subnanomolar CA IV inhibitors. Bioorganic & Medicinal Chemistry 25:2, pages 539-544.
Crossref
Crossref
Alessio Nocentini, Marta Ferraroni, Fabrizio Carta, Mariangela Ceruso, Paola Gratteri, Cecilia Lanzi, Emanuela Masini & Claudiu T. Supuran. (2016) Benzenesulfonamides Incorporating Flexible Triazole Moieties Are Highly Effective Carbonic Anhydrase Inhibitors: Synthesis and Kinetic, Crystallographic, Computational, and Intraocular Pressure Lowering Investigations. Journal of Medicinal Chemistry 59:23, pages 10692-10704.
Crossref
Crossref
Samet Mert, Zuhal Alım, Mehmet Mustafa İşgör, Şükrü Beydemir & Rahmi Kasımoğulları. (2016) The synthesis of novel pyrazole-3,4-dicarboxamides bearing 5-amino-1,3,4-thiadiazole-2-sulfonamide moiety with effective inhibitory activity against the isoforms of human cytosolic carbonic anhydrase I and II. Bioorganic Chemistry 68, pages 64-71.
Crossref
Crossref
Daniel A. Ryskamp, Amber M. Frye, Tam T. T. Phuong, Oleg Yarishkin, Andrew O. Jo, Yong Xu, Monika Lakk, Anthony Iuso, Sarah N. Redmon, Balamurali Ambati, Gregory Hageman, Glenn D. Prestwich, Karen Y. Torrejon & David Križaj. (2016) TRPV4 regulates calcium homeostasis, cytoskeletal remodeling, conventional outflow and intraocular pressure in the mammalian eye. Scientific Reports 6:1.
Crossref
Crossref
Fabrizio Carta & Claudiu T. Supuran. 2016. Bioactive Carboxylic Compound Classes: Pharmaceuticals and Agrochemicals. Bioactive Carboxylic Compound Classes: Pharmaceuticals and Agrochemicals
269
279
.
Daniela Vullo, Claudiu T. Supuran, Andrea Scozzafava, Giuseppina De Simone, Simona Maria Monti, Vincenzo Alterio & Fabrizio Carta. (2016) Kinetic and X-ray crystallographic investigations of substituted 2-thio-6-oxo-1,6-dihydropyrimidine–benzenesulfonamides acting as carbonic anhydrase inhibitors. Bioorganic & Medicinal Chemistry 24:16, pages 3643-3648.
Crossref
Crossref
Daniela Vullo, Mariaconcetta Durante, Francesco Saverio Di Leva, Sandro Cosconati, Emanuela Masini, Andrea Scozzafava, Ettore Novellino, Claudiu T. Supuran & Fabrizio Carta. (2016) Monothiocarbamates Strongly Inhibit Carbonic Anhydrases in Vitro and Possess Intraocular Pressure Lowering Activity in an Animal Model of Glaucoma. Journal of Medicinal Chemistry 59:12, pages 5857-5867.
Crossref
Crossref
Yaru Dong, Yu Sawada, Jizhe Cui, Masahiro Hayakawa, Dai Ogino, Makoto Ishikawa & Takeshi Yoshitomi. (2016) Dorzolamide-induced relaxation of isolated rabbit ciliary arteries mediated by inhibition of extracellular calcium influx. Japanese Journal of Ophthalmology 60:2, pages 103-110.
Crossref
Crossref
Elizabeth A. Cairns, William H. Baldridge & Melanie E. M. Kelly. (2016) The Endocannabinoid System as a Therapeutic Target in Glaucoma. Neural Plasticity 2016, pages 1-10.
Crossref
Crossref
Ylenia Cau, Mattia Mori, Claudiu T. Supuran & Maurizio Botta. (2016) Mycobacterial carbonic anhydrase inhibition with phenolic acids and esters: kinetic and computational investigations. Organic & Biomolecular Chemistry 14:35, pages 8322-8330.
Crossref
Crossref
Alex S. Huang, Lilit Minasyan & Robert N. Weinreb. 2017. Pharmacologic Therapy of Ocular Disease. Pharmacologic Therapy of Ocular Disease
181
207
.
Cenzo Congiu, Valentina Onnis, Alessandro Deplano, Gianfranco Balboni, Nurcan Dedeoglu & Claudiu T. Supuran. (2015) Synthesis of sulfonamides incorporating piperazinyl-ureido moieties and their carbonic anhydrase I, II, IX and XII inhibitory activity. Bioorganic & Medicinal Chemistry Letters 25:18, pages 3850-3853.
Crossref
Crossref
Natasha M. Rogers & Jeffrey S. Isenberg. (2015)
Seeing is believing: NO therapy for glaucoma?
Focus on “Role of nitric oxide in murine conventional outflow physiology”
. American Journal of Physiology-Cell Physiology 309:4, pages C203-C204.
Crossref
Crossref
Leo Syrjänen, Marianne Kuuslahti, Martti Tolvanen, Daniela Vullo, Seppo Parkkila & Claudiu T. Supuran. (2015) The β-carbonic anhydrase from the malaria mosquito Anopheles gambiae is highly inhibited by sulfonamides. Bioorganic & Medicinal Chemistry 23:10, pages 2303-2309.
Crossref
Crossref
Fabrizio Carta, Lorenzo Di Cesare Mannelli, Melissa Pinard, Carla Ghelardini, Andrea Scozzafava, Robert McKenna & Claudiu T. Supuran. (2015) A class of sulfonamide carbonic anhydrase inhibitors with neuropathic pain modulating effects. Bioorganic & Medicinal Chemistry 23:8, pages 1828-1840.
Crossref
Crossref
Aiga Grandane, Muhammet Tanc, Raivis Žalubovskis & Claudiu T. Supuran. (2015) Synthesis of 6-aryl-substituted sulfocoumarins and investigation of their carbonic anhydrase inhibitory action. Bioorganic & Medicinal Chemistry 23:7, pages 1430-1436.
Crossref
Crossref
Simone Carradori, Adriano Mollica, Celeste De Monte, Arianna Granese & Claudiu Supuran. (2015) Nitric Oxide Donors and Selective Carbonic Anhydrase Inhibitors: A Dual Pharmacological Approach for the Treatment of Glaucoma, Cancer and Osteoporosis. Molecules 20:4, pages 5667-5679.
Crossref
Crossref
Fernando Huete-Toral, Almudena Crooke, Alejandro Martínez-Águila & Jesús Pintor. (2015) Melatonin Receptors Trigger cAMP Production and Inhibit Chloride Movements in Nonpigmented Ciliary Epithelial Cells. Journal of Pharmacology and Experimental Therapeutics 352:1, pages 119-128.
Crossref
Crossref
V. Alterio, M. Tanc, J. Ivanova, R. Zalubovskis, I. Vozny, S. M. Monti, A. Di Fiore, G. De Simone & C. T. Supuran. (2015) X-ray crystallographic and kinetic investigations of 6-sulfamoyl-saccharin as a carbonic anhydrase inhibitor. Organic & Biomolecular Chemistry 13:13, pages 4064-4069.
Crossref
Crossref
Clemente Capasso & Claudiu T. Supuran. 2015. Carbonic Anhydrases as Biocatalysts. Carbonic Anhydrases as Biocatalysts
275
288
.
Claudiu T. Supuran, Clemente Capasso & Giuseppina De Simone. 2015. Carbonic Anhydrases as Biocatalysts. Carbonic Anhydrases as Biocatalysts
51
90
.
Murat Bozdag, Melissa Pinard, Fabrizio Carta, Emanuela Masini, Andrea Scozzafava, Robert McKenna & Claudiu T. Supuran. (2014) A Class of 4-Sulfamoylphenyl-ω-aminoalkyl Ethers with Effective Carbonic Anhydrase Inhibitory Action and Antiglaucoma Effects. Journal of Medicinal Chemistry 57:22, pages 9673-9686.
Crossref
Crossref
Busra Sarikaya, Mariangela Ceruso, Fabrizio Carta & Claudiu T. Supuran. (2014) Inhibition of carbonic anhydrase isoforms I, II, IX and XII with novel Schiff bases: Identification of selective inhibitors for the tumor-associated isoforms over the cytosolic ones. Bioorganic & Medicinal Chemistry 22:21, pages 5883-5890.
Crossref
Crossref
Claudiu T Supuran & Clemente CapassoSébastien ThibaudeauHélène CarreyreAgnès MingotClaudiu T Supuran. 2014. Targeting Carbonic Anhydrases. Targeting Carbonic Anhydrases
52
67
.
Ahmed M. Alafeefy, Mariangela Ceruso, Abdul-Malek S. Al-Tamimi, Sonia Del Prete, Clemente Capasso & Claudiu T. Supuran. (2014) Quinazoline–sulfonamides with potent inhibitory activity against the α-carbonic anhydrase from Vibrio cholerae. Bioorganic & Medicinal Chemistry 22:19, pages 5133-5140.
Crossref
Crossref
Mohamed-Chiheb Saada, Daniela Vullo, Jean-Louis Montero, Andrea Scozzafava, Claudiu T. Supuran & Jean-Yves Winum. (2014) Mono- and di-halogenated histamine, histidine and carnosine derivatives are potent carbonic anhydrase I, II, VII, XII and XIV activators. Bioorganic & Medicinal Chemistry 22:17, pages 4752-4758.
Crossref
Crossref
Fabrizio Carta, Claudiu T Supuran & Andrea Scozzafava. (2014) Sulfonamides and their isosters as carbonic anhydrase inhibitors. Future Medicinal Chemistry 6:10, pages 1149-1165.
Crossref
Crossref
Cenzo Congiu, Valentina Onnis, Gianfranco Balboni & Claudiu T. Supuran. (2014) Synthesis and carbonic anhydrase I, II, IX and XII inhibition studies of 4-N,N-disubstituted sulfanilamides incorporating 4,4,4-trifluoro-3-oxo-but-1-enyl, phenacylthiourea and imidazol-2(3H)-one/thione moieties. Bioorganic & Medicinal Chemistry Letters 24:7, pages 1776-1779.
Crossref
Crossref
Amrita K. Saluja, Meena Tiwari, Daniela Vullo & Claudiu T. Supuran. (2014) Substituted benzene sulfonamides incorporating 1,3,5-triazinyl moieties potently inhibit human carbonic anhydrases II, IX and XII. Bioorganic & Medicinal Chemistry Letters 24:5, pages 1310-1314.
Crossref
Crossref
Melissa D’Ascenzio, Simone Carradori, Celeste De Monte, Daniela Secci, Mariangela Ceruso & Claudiu T. Supuran. (2014) Design, synthesis and evaluation of N-substituted saccharin derivatives as selective inhibitors of tumor-associated carbonic anhydrase XII. Bioorganic & Medicinal Chemistry 22:6, pages 1821-1831.
Crossref
Crossref
Aiga Grandane, Muhammet Tanc, Raivis Zalubovskis & Claudiu T. Supuran. (2014) Synthesis of 6-tetrazolyl-substituted sulfocoumarins acting as highly potent and selective inhibitors of the tumor-associated carbonic anhydrase isoforms IX and XII. Bioorganic & Medicinal Chemistry 22:5, pages 1522-1528.
Crossref
Crossref
Ahmed M. Alafeefy, Hatem A. Abdel-Aziz, Daniela Vullo, Abdul-Malek S. Al-Tamimi, Nabila A. Al-Jaber, Clemente Capasso & Claudiu T. Supuran. (2014) Inhibition of carbonic anhydrases from the extremophilic bacteria Sulfurihydrogenibium yellostonense (SspCA) and S. azorense (SazCA) with a new series of sulfonamides incorporating aroylhydrazone-, [1,2,4]triazolo[3,4-b][1,3,4]thiadiazinyl- or 2-(cyanophenylmethylene)-1,3,4-thiadiazol-3(2H)-yl moieties. Bioorganic & Medicinal Chemistry 22:1, pages 141-147.
Crossref
Crossref
Andrea Scozzafava & Claudiu T. Supuran. 2014. Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications. Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications
349
359
.
Robert McKenna & Claudiu T. Supuran. 2014. Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications. Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications
291
323
.
Mariangela Ceruso, Daniela Vullo, Andrea Scozzafava & Claudiu T. Supuran. (2013) Inhibition of human carbonic anhydrase isoforms I–XIV with sulfonamides incorporating fluorine and 1,3,5-triazine moieties. Bioorganic & Medicinal Chemistry 21:22, pages 6929-6936.
Crossref
Crossref
Özlen Güzel-Akdemir, Atilla Akdemir, Peiwen Pan, Alane B. Vermelho, Seppo Parkkila, Andrea Scozzafava, Clemente Capasso & Claudiu T. Supuran. (2013)
A Class of Sulfonamides with Strong Inhibitory Action against the α-Carbonic Anhydrase from
Trypanosoma cruzi
. Journal of Medicinal Chemistry 56:14, pages 5773-5781.
Crossref
Crossref
Fabrizio Carta, Atilla Akdemir, Andrea Scozzafava, Emanuela Masini & Claudiu T. Supuran. (2013) Xanthates and Trithiocarbonates Strongly Inhibit Carbonic Anhydrases and Show Antiglaucoma Effects in Vivo. Journal of Medicinal Chemistry 56:11, pages 4691-4700.
Crossref
Crossref
Ana Guzman-AranguezBasilio ColligrisJesús Pintor. (2013) Contact Lenses: Promising Devices for Ocular Drug Delivery. Journal of Ocular Pharmacology and Therapeutics 29:2, pages 189-199.
Crossref
Crossref
Daniel D. Long, Bryan Frieman, Sharath S. Hegde, Craig M. Hill, Lan Jiang, Samuel Kintz, Daniel G. Marquess, Hans Purkey, Jeng-Pyng Shaw, Tod Steinfeld, Michael S. Wilson & Kevin Wrench. (2013) A multivalent approach towards linked dual-pharmacology prostaglandin F receptor agonist/carbonic anhydrase-II inhibitors for the treatment of glaucoma. Bioorganic & Medicinal Chemistry Letters 23:4, pages 939-943.
Crossref
Crossref
Benoît Métayer, Agnès Martin-Mingot, Daniella Vullo, Claudiu. T. Supuran & Sébastien Thibaudeau. (2013) Superacid synthesized tertiary benzenesulfonamides and benzofuzed sultams act as selective hCA IX inhibitors: toward understanding a new mode of inhibition by tertiary sulfonamides. Organic & Biomolecular Chemistry 11:43, pages 7540.
Crossref
Crossref
Benoît Métayer, Agnès Mingot, Daniella Vullo, Claudiu. T. Supuran & Sébastien Thibaudeau. (2013) New superacid synthesized (fluorinated) tertiary benzenesulfonamides acting as selective hCA IX inhibitors: toward a new mode of carbonic anhydrase inhibition by sulfonamides. Chemical Communications 49:54, pages 6015.
Crossref
Crossref
Sara McNally & Colm J. O’Brien. (2013) Drug discovery in glaucoma and the role of animal models. Drug Discovery Today: Disease Models 10:4, pages e207-e214.
Crossref
Crossref
Gianfranco Balboni, Cenzo Congiu, Valentina Onnis, Alfonso Maresca, Andrea Scozzafava, Jean-Yves Winum, Annalisa Maietti & Claudiu T. Supuran. (2012) Flavones and structurally related 4-chromenones inhibit carbonic anhydrases by a different mechanism of action compared to coumarins. Bioorganic & Medicinal Chemistry Letters 22:9, pages 3063-3066.
Crossref
Crossref
Fabrizio Carta, Daniela Vullo, Alfonso Maresca, Andrea Scozzafava & Claudiu T. Supuran. (2012) New chemotypes acting as isozyme-selective carbonic anhydrase inhibitors with low affinity for the offtarget cytosolic isoform II. Bioorganic & Medicinal Chemistry Letters 22:6, pages 2182-2185.
Crossref
Crossref
Fabrizio Carta, Mayank Aggarwal, Alfonso Maresca, Andrea Scozzafava, Robert McKenna, Emanuela Masini & Claudiu T. Supuran. (2012) Dithiocarbamates Strongly Inhibit Carbonic Anhydrases and Show Antiglaucoma Action in Vivo. Journal of Medicinal Chemistry 55:4, pages 1721-1730.
Crossref
Crossref