105
Views
26
CrossRef citations to date
0
Altmetric
Review

Therapeutic potential of positive AMPA receptor modulators in the treatment of neurological disease

Pages 765-777 | Published online: 24 Feb 2005

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Fulvio Gualtieri. (2016) Unifi nootropics from the lab to the web: a story of academic (and industrial) shortcomings. Journal of Enzyme Inhibition and Medicinal Chemistry 31:2, pages 187-194.
Read now
Ruth O'Hara, Christian Derouesné, Konstantinos N. Fountoulakis & Jerome A. Yesavage. (2001) Therapeutic approaches to age-associated neurocognitive disorders. Dialogues in Clinical Neuroscience 3:3, pages 191-213.
Read now
Simon JA Grove, Gary A Rogers & Ming-Qiang Zhang. (2000) Positive modulators of the AMPA receptor. Expert Opinion on Therapeutic Patents 10:10, pages 1539-1548.
Read now

Articles from other publishers (23)

Loïs S. Miraucourt, Michael V. Accardi, Karen E. Asin, Michael K. Pugsley, Michael J. Curtis & Simon Authier. (2020) The application of electrophysiological methods to characterize AMPA receptors in dissociated adult rat and non-human primate cerebellar neurons for use in neuronal safety pharmacology assessments of the central nervous system. Journal of Pharmacological and Toxicological Methods 105, pages 106883.
Crossref
Fanny CF Ip, Wing-Yu Fu, Elaine YL Cheng, Estella PS Tong, Ka-Chun Lok, Yan Liang, Wen-Cai Ye & Nancy Y Ip. (2015) Anemoside A3 Enhances Cognition through the Regulation of Synaptic Function and Neuroprotection. Neuropsychopharmacology 40:8, pages 1877-1887.
Crossref
Maria Soto, Sandrine Andrieu, Fati Nourhashemi, Pierre Jean Ousset, Clive Ballard, Philippe Robert, Bruno Vellas, Constantine G. Lyketsos & Paul B. Rosenberg. (2014) Medication development for agitation and aggression in Alzheimer disease: review and discussion of recent randomized clinical trial design. International Psychogeriatrics 27:2, pages 181-197.
Crossref
Paula T. Trzepacz, Jeffrey Cummings, Thomas Konechnik, Tammy D. Forrester, Curtis Chang, Ellen B. Dennehy, Brian A. Willis, Catherine Shuler, Linda B. Tabas & Constantine Lyketsos. (2012) Mibampator (LY451395) randomized clinical trial for agitation/aggression in Alzheimer's disease. International Psychogeriatrics 25:5, pages 707-719.
Crossref
M Vandesquille, I Carrié, C Louis, D Beracochea & P Lestage. (2011) Effects of positive modulators of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors in a benzodiazepine-induced deficit of spatial discrimination in mice. Journal of Psychopharmacology 26:6, pages 845-856.
Crossref
Marina Boziki, Vassilis Papaliagkas & Magda Tsolaki. 2011. The Handbook of Alzheimer's Disease and Other Dementias. The Handbook of Alzheimer's Disease and Other Dementias 277 300 .
Matthias Vandesquille, Ali Krazem, Caroline Louis, Pierre Lestage & Daniel Béracochéa. (2011) S 18986 reverses spatial working memory impairments in aged mice: comparison with memantine. Psychopharmacology 215:4, pages 709-720.
Crossref
Katy Bernard, Laurence Danober, Jean-Yves Thomas, Cécile Lebrun, Carmen Muñoz, Alex Cordi, Patrice Desos, Pierre Lestage & Philippe Morain. (2010) DRUG FOCUS: S 18986: A Positive Allosteric Modulator of AMPA-Type Glutamate Receptors Pharmacological Profile of a Novel Cognitive Enhancer. CNS Neuroscience & Therapeutics 16:5, pages e193-e212.
Crossref
Eric Schaeffer & Allen Duplantier. 2010. Neurodegenerative Diseases. Neurodegenerative Diseases 91 147 .
Erik B. Bloss, Richard G. Hunter, Elizabeth M. Waters, Carmen Munoz, Katie Bernard & Bruce S. McEwen. (2008) Behavioral and biological effects of chronic S18986, a positive AMPA receptor modulator, during aging. Experimental Neurology 210:1, pages 109-117.
Crossref
John B. Davis, C. Bountra & J. Richardson. 2008. Dementias. Dementias 273 290 .
Edward R. Siuda, Jennifer C. Quirk & Eric S. Nisenbaum. 2007. Patch-Clamp Methods and Protocols. Patch-Clamp Methods and Protocols 37 57 .
Kota Kato, Kiyoshi Noguchi, Toshiko Aoki, Yoshiaki Soeishi & Hidetaka Kamimura. (2006) Simultaneous determination of YM928, a novel noncompetitive AMPA receptor antagonist, and its demethylated metabolite in rat, dog and monkey plasma by high-performance liquid chromatography with ultraviolet detection. Biomedical Chromatography 20:12, pages 1328-1335.
Crossref
Maria-Carmen Fernandez, Ana Casta?o, Esteban Dominguez, Ana Escribano, Delu Jiang, Alma Jimenez, Eric Hong, William J. Hornback, Eric S. Nisenbaum, Nancy Rankl, Eric Tromiczak, Grant Vaught, Hamideh Zarrinmayeh & Dennis M. Zimmerman. (2006) A novel class of AMPA receptor allosteric modulators. Part 1: Design, synthesis, and SAR of 3-aryl-4-cyano-5-substituted-heteroaryl-2-carboxylic acid derivatives. Bioorganic & Medicinal Chemistry Letters 16:19, pages 5057-5061.
Crossref
M. N. Romanelli, N. Galeotti, C. Ghelardini, D. Manetti, E. Martini & F. Gualtieri. (2006) Pharmacological Characterization of DM232 (Unifiram) and DM235 (Sunifiram), New Potent Cognition Enhancers. CNS Drug Reviews 12:1, pages 39-52.
Crossref
Nicholas Jones, Michael J. O’Neill, Mark Tricklebank, Vincenzo Libri & Steve C. R. Williams. (2005) Examining the neural targets of the AMPA receptor potentiator LY404187 in the rat brain using pharmacological magnetic resonance imaging. Psychopharmacology 180:4, pages 743-751.
Crossref
Serena Scapecchi, Elisabetta Martini, Dina Manetti, Carla Ghelardini, Cecilia Martelli, Silvia Dei, Nicoletta Galeotti, Luca Guandalini, Maria Novella Romanelli & Elisabetta Teodori. (2004) Structure–activity relationship studies on unifiram (DM232) and sunifiram (DM235), two novel and potent cognition enhancing drugs. Bioorganic & Medicinal Chemistry 12:1, pages 71-85.
Crossref
Jennifer C. Quirk & Eric S. Nisenbaum. (2003) Multiple Molecular Determinants for Allosteric Modulation of Alternatively Spliced AMPA Receptors. The Journal of Neuroscience 23:34, pages 10953-10962.
Crossref
Philip K. Liu & Tarun Arora. (2002) Transcripts of damaged genes in the brain during cerebral oxidative stress. Journal of Neuroscience Research 70:6, pages 713-720.
Crossref
Jennifer C. Quirk & Eric S. Nisenbaum. (2006) LY404187: A Novel Positive Allosteric Modulator of AMPA Receptors. CNS Drug Reviews 8:3, pages 255-282.
Crossref
Nikolaus Seiler. (2002) Ammonia and Alzheimer’s disease. Neurochemistry International 41:2-3, pages 189-207.
Crossref
Dean Phillips, Jennifer Sonnenberg, Amy C Arai, Rishi Vaswani, Peter O Krutzik, Thomas Kleisli, Markus Kessler, Richard Granger, Gary Lynch & A Richard Chamberlin. (2002) 5?-Alkyl-benzothiadiazides: A New Subgroup of AMPA Receptor Modulators with Improved Affinity. Bioorganic & Medicinal Chemistry 10:5, pages 1229-1248.
Crossref
Wolfgang Fischer, Heike Franke, Peter Scheibler, Clemens Allgaier & Peter Illes. (2002) AMPA-induced Ca2+ influx in cultured rat cortical nonpyramidal neurones: pharmacological characterization using fura-2 microfluorimetry. European Journal of Pharmacology 438:1-2, pages 53-62.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.