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Jeffrey Gudin & Jeffrey Fudin. (2020) Peripheral Opioid Receptor Antagonists for Opioid-Induced Constipation: A Primer on Pharmacokinetic Variabilities with a Focus on Drug Interactions. Journal of Pain Research 13, pages 447-456.
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Wojciech Leppert, Renata Zajaczkowska & Jerzy Wordliczek. (2019) The role of oxycodone/naloxone in the management of patients with pain and opioid-induced constipation. Expert Opinion on Pharmacotherapy 20:5, pages 511-522.
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Carsten Bantel, Shiva S Tripathi, David Molony, Tony Heffernan, Susmita Oomman, Vivek Mehta & Sara Dickerson. (2018) Prolonged-release oxycodone/naloxone reduces opioid-induced constipation and improves quality of life in laxative-refractory patients: results of an observational study. Clinical and Experimental Gastroenterology 11, pages 57-67.
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Joanne Patel, Catherine J. Lucas, Maxwell Margalit & Jennifer H. Martin. (2018) Laxative Use in Inpatients on Oxycodone/Naloxone Prolonged Release and Oxycodone Prolonged Release for Cancer and Non-cancer Pain. Journal of Pain & Palliative Care Pharmacotherapy 32:2-3, pages 116-123.
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Joseph V Pergolizzi$suffix/text()$suffix/text(), Robert B Raffa, Marco Pappagallo, Charles Fleischer, Joseph Pergolizzi$suffix/text()$suffix/text(), Gianpietro Zampogna, Elizabeth Duval, Janan Hishmeh, Jo Ann LeQuang & Robert Taylor$suffix/text()$suffix/text(). (2017) Peripherally acting μ-opioid receptor antagonists as treatment options for constipation in noncancer pain patients on chronic opioid therapy. Patient Preference and Adherence 11, pages 107-119.
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Gineke Koopmans-Klein, Joeri Van Op den Bosch, Yvonne van Megen, Hans Prenen, Frank Huygen & Isabelle Mancini. (2017) Prolonged release oxycodone and naloxone treatment counteracts opioid-induced constipation in patients with severe pain compared to previous analgesic treatment. Current Medical Research and Opinion 33:12, pages 2217-2227.
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Emiliano Petrò, Elena Ruffini, Melania Cappuccio, Valeria Guerini, Gloria Belotti, Sara Fascendini, Cristina Licini & Claudio Marcassa. (2016) Low-dose oral prolonged-release oxycodone/naloxone for chronic pain in elderly patients with cognitive impairment: an efficacy–tolerability pilot study. Neuropsychiatric Disease and Treatment 12, pages 559-569.
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Stefano de Biase, Mariarosaria Valente & Gian Luigi Gigli. (2016) Intractable restless legs syndrome: role of prolonged-release oxycodone–naloxone. Neuropsychiatric Disease and Treatment 12, pages 417-425.
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Fabio Guerriero, Anna Roberto, Maria Teresa Greco, Carmelo Sgarlata, Marco Rollone & Oscar Corli. (2016) Long-term efficacy and safety of oxycodone–naloxone prolonged release in geriatric patients with moderate-to-severe chronic noncancer pain: a 52-week open-label extension phase study. Drug Design, Development and Therapy 10, pages 1515-1523.
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Stefano de Biase, Giovanni Merlino, Mariarosaria Valente & Gian Luigi Gigli. (2016) Opioids in the treatment of restless legs syndrome: pharmacological and clinical aspects. Expert Opinion on Drug Metabolism & Toxicology 12:9, pages 1035-1045.
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Gineke Koopmans-Klein, Michel F.M. Wagemans, Hans C.H. Wartenberg, Yvonne J.B. Van Megen & Frank J.P.M. Huygen. (2016) The efficacy of standard laxative use for the prevention and treatment of opioid induced constipation during oxycodone use: a small Dutch observational pilot study. Expert Review of Gastroenterology & Hepatology 10:4, pages 547-553.
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Ron Goeree & Jeff Goeree. (2016) Cost-effectiveness analysis of oxycodone with naloxone versus oxycodone alone for the management of moderate-to-severe pain in patients with opioid-induced constipation in Canada. Journal of Medical Economics 19:3, pages 277-291.
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Marzia Lazzari, Claudio Marcassa, Silvia Natoli, Roberta Carpenedo, Clarissa Caldarulo, Maria B Silvi & Mario Dauri. (2016) Switching to low-dose oral prolonged-release oxycodone/naloxone from WHO-Step I drugs in elderly patients with chronic pain at high risk of early opioid discontinuation. Clinical Interventions in Aging 11, pages 641-649.
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Michael A Ueberall & Gerhard HH Mueller-Schwefe. (2015) Development of opioid-induced constipation: post hoc analysis of data from a 12-week prospective, open-label, blinded-endpoint streamlined study in low-back pain patients treated with prolonged-release WHO step III opioids. Journal of Pain Research 8, pages 459-475.
Read now
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Marzia Lazzari, Maria Teresa Greco, Claudio Marcassa, Simona Finocchi, Clarissa Caldarulo & Oscar Corli. (2015) Efficacy and tolerability of oral oxycodone and oxycodone/naloxone combination in opioid-naïve cancer patients: a propensity analysis. Drug Design, Development and Therapy 9, pages 5863-5872.
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Guido Fanelli & Andrea Fanelli. (2015) Developments in managing severe chronic pain: role of oxycodone–naloxone extended release. Drug Design, Development and Therapy 9, pages 3811-3816.
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Wojciech Leppert. (2015) Emerging therapies for patients with symptoms of opioid-induced bowel dysfunction. Drug Design, Development and Therapy 9, pages 2215-2231.
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Michael A. Ueberall & Gerhard H. H. Mueller-Schwefe. (2015) Safety and efficacy of oxycodone/naloxone vs. oxycodone vs. morphine for the treatment of chronic low back pain: results of a 12 week prospective, randomized, open-label blinded endpoint streamlined study with prolonged-release preparations. Current Medical Research and Opinion 31:7, pages 1413-1429.
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Fabio Guerriero, Niccolo Maurizi, Matthew Francis, Carmelo Sgarlata, Giovanni Ricevuti, Mariangela Rondanelli, Simone Perna & Marco Rollone. (2015) Is oxycodone/naloxone effective and safe in managing chronic pain of a fragile elderly patient with multiple skin ulcers of the lower limbs? A case report. Clinical Interventions in Aging 10, pages 1283-1287.
Read now
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Fabio Guerriero, Carmelo Sgarlata, Claudio Marcassa, Giovanni Ricevuti & Marco Rollone. (2015) Efficacy and tolerability of low-dose oral prolonged-release oxycodone/naloxone for chronic nononcological pain in older patients. Clinical Interventions in Aging 10, pages 1-11.
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Waldemar Siemens, Jan Gaertner & Gerhild Becker. (2015) Advances in pharmacotherapy for opioid-induced constipation – a systematic review. Expert Opinion on Pharmacotherapy 16:4, pages 515-532.
Read now
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Sabine Hesselbarth, Kai Hermanns & Petra Oepen. (2015) Prolonged-release oxycodone/naloxone in opioid-naïve patients – subgroup analysis of a prospective observational study. Expert Opinion on Pharmacotherapy 16:4, pages 457-464.
Read now
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Carmelo Scarpignato & Luigi Gatta. (2015) Comparing tapentadol to oxycodone/naloxone combination: building castles in the air. Current Medical Research and Opinion 31:2, pages 335-338.
Read now
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Thomas Nolte, Ulf Schutter & Oliver Loewenstein. (2014) Cancer pain therapy with a fixed combination of prolonged-release oxycodone/naloxone: results from a non-interventional study. Pragmatic and Observational Research 5, pages 1-13.
Read now
Read now
Karin S Coyne, Robert J LoCasale, Catherine J Datto, Chris C Sexton, Karen Yeomans & Jan Tack. (2014) Opioid-induced constipation in patients with chronic noncancer pain in the USA, Canada, Germany, and the UK: descriptive analysis of baseline patient-reported outcomes and retrospective chart review. ClinicoEconomics and Outcomes Research 6, pages 269-281.
Read now
Read now
Gineke Koopmans, Karen Simpson, Javier De Andrés, Eberhard Albert Lux, Michel Wagemans & Yvonne Van Megen. (2014) Fixed ratio (2:1) prolonged-release oxycodone/naloxone combination improves bowel function in patients with moderate-to-severe pain and opioid-induced constipation refractory to at least two classes of laxatives. Current Medical Research and Opinion 30:11, pages 2389-2396.
Read now
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Flaminia Coluzzi & Matteo Ruggeri. (2014) Clinical and economic evaluation of tapentadol extended release and oxycodone/naloxone extended release in comparison with controlled release oxycodone in musculoskeletal pain. Current Medical Research and Opinion 30:6, pages 1139-1151.
Read now
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Mellar Davis, Harold W Goforth & Pam Gamier. (2013) Oxycodone combined with opioid receptor antagonists: efficacy and safety. Expert Opinion on Drug Safety 12:3, pages 389-402.
Read now
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Sabine Bader, Thorsten Dürk & Gerhild Becker. (2013) Methylnaltrexone for the treatment of opioid-induced constipation. Expert Review of Gastroenterology & Hepatology 7:1, pages 13-26.
Read now
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Sebastiano Mercadante & Antonello Giarratano. (2013) Combined oral prolonged-release oxycodone and naloxone in chronic pain management. Expert Opinion on Investigational Drugs 22:1, pages 161-166.
Read now
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Kai Hermanns, Uwe Junker & Thomas Nolte. (2012) Prolonged-release oxycodone/naloxone in the treatment of neuropathic pain – results from a large observational study. Expert Opinion on Pharmacotherapy 13:3, pages 299-311.
Read now
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William Dunlop, Reiner Uhl, Iftekhar Khan, Anna Taylor & Garry Barton. (2012) Quality of life benefits and cost impact of prolonged release oxycodone/naloxone versus prolonged release oxycodone in patients with moderate-to-severe non-malignant pain and opioid-induced constipation: a UK cost-utility analysis. Journal of Medical Economics 15:3, pages 564-575.
Read now
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Laura Diego, Rabia Atayee, Pieter Helmons, Grace Hsiao & Charles F von Gunten. (2011) Novel opioid antagonists for opioid-induced bowel dysfunction. Expert Opinion on Investigational Drugs 20:8, pages 1047-1056.
Read now
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Karsten Ahlbeck. (2011) Opioids: a two-faced Janus. Current Medical Research and Opinion 27:2, pages 439-448.
Read now
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Katri Elina Clemens & Gerd Mikus. (2010) Combined oral prolonged-release oxycodone and naloxone in opioid-induced bowel dysfunction: review of efficacy and safety data in the treatment of patients experiencing chronic pain. Expert Opinion on Pharmacotherapy 11:2, pages 297-310.
Read now
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Joanne Droney & Julia Riley. (2009) Recent advances in the use of opioids for cancer pain. Journal of Pain Research 2, pages 135-155.
Read now
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Articles from other publishers (94)
Rob Hill & Meritxell Canals. (2022) Experimental considerations for the assessment of in vivo and in vitro opioid pharmacology. Pharmacology & Therapeutics 230, pages 107961.
Crossref
Crossref
. 2022. Arzneimitteltherapie in der Palliativmedizin. Arzneimitteltherapie in der Palliativmedizin
511
774
.
Michael Camilleri. 2022. Comprehensive Pharmacology. Comprehensive Pharmacology
76
99
.
Patrice Forget & Mathieu Vermeersch. (2020) To what extent are we confident that tapentadol induces less constipation and other side effects than the other opioids in chronic pain patients? a confidence evaluation in network meta-analysis. British Journal of Pain 15:4, pages 380-387.
Crossref
Crossref
Matteo Ruggeri, Alessandro Signorini, Silvia Caravaggio, Costanza Santori, Francesco Rosiello & Flaminia Coluzzi. (2021) Cost-Effectiveness Analysis of Tapentadol Versus Oxycodone/Naloxone in both Branded and Generic Formulations in Patients with Musculoskeletal Pain. Clinical Drug Investigation 41:10, pages 875-883.
Crossref
Crossref
Rong Ouyang, Zhongzhuan Li, Shijiang Huang, Jun Liu & Jiean Huang. (2020) Efficacy and Safety of Peripherally Acting Mu-Opioid Receptor Antagonists for the Treatment of Opioid-Induced Constipation: A Bayesian Network Meta-analysis. Pain Medicine 21:11, pages 3224-3232.
Crossref
Crossref
Priya Vijayvargiya, Michael Camilleri, Pooja Vijayvargiya, Patricia Erwin & M. Hassan Murad. (2020) Systematic review with meta-analysis: efficacy and safety of treatments for opioid-induced constipation. Alimentary Pharmacology & Therapeutics 52:1, pages 37-53.
Crossref
Crossref
Katherine ClarkPaul G. ByrneJane HuntLinda BrownDebra RowettGareth WattsMelanie LovellDavid C. Currow. (2020) Pharmacovigilance in Hospice/Palliative Care: De-Prescribing Combination Controlled Release Oxycodone-Naloxone. Journal of Palliative Medicine 23:5, pages 656-661.
Crossref
Crossref
Xiaomei Leng, Fengxiao Zhang, Shanglong Yao, Xisheng Weng, Kaizhi Lu, Gouzhong Chen, Ming Huang, Yuguang Huang, Xiaofeng Zeng, Michael Hopp & Guodong Lu. (2020) Prolonged-Release (PR) Oxycodone/Naloxone Improves Bowel Function Compared with Oxycodone PR and Provides Effective Analgesia in Chinese Patients with Non-malignant Pain: A Randomized, Double-Blind Trial. Advances in Therapy 37:3, pages 1188-1202.
Crossref
Crossref
Namisha Thapa, Matthew Kappus, Ryan Hurt & Sarah Diamond. (2019) Implications of the Opioid Epidemic for the Clinical Gastroenterology Practice. Current Gastroenterology Reports 21:9.
Crossref
Crossref
Nicholas E Burr & Alexander C Ford. (2019) Assessing the efficacy of peripherally acting µ-opioid receptor antagonists (PAMORAs) in the treatment of opioid-induced constipation: authors reply. Gut 68:8, pages 1530-1531.
Crossref
Crossref
Victor Chedid & Michael Camilleri. (2019) Assessing the efficacy of peripherally acting mu-opioid receptor antagonists (PAMORAs) in the treatment of opioid-induced constipation. Gut 68:6, pages 1133-1134.
Crossref
Crossref
Ammar A.H. Azzam, John McDonald & David G. Lambert. (2019) Hot topics in opioid pharmacology: mixed and biased opioids. British Journal of Anaesthesia 122:6, pages e136-e145.
Crossref
Crossref
Anne Leuppi-Taegtmeyer, Urs Duthaler, Felix Hammann, Yasmin Schmid, Michael Dickenmann, Patricia Amico, Andreas W Jehle, Stefan Kalbermatter, Christoph Lenherr, Henriette E Meyer zu Schwabedissen, Manuel Haschke, Matthias E Liechti & Stephan Krähenbühl. (2019) Pharmacokinetics of oxycodone/naloxone and its metabolites in patients with end-stage renal disease during and between haemodialysis sessions. Nephrology Dialysis Transplantation 34:4, pages 692-702.
Crossref
Crossref
Pavit Luthra, Nicholas E Burr, Darren M Brenner & Alexander C Ford. (2019) Efficacy of pharmacological therapies for the treatment of opioid-induced constipation: systematic review and network meta-analysis. Gut 68:3, pages 434-444.
Crossref
Crossref
Adam D Farmer, Asbjørn M Drewes, Giuseppe Chiarioni, Roberto De Giorgio, Tony O'Brien, Bart Morlion & Jan Tack. (2019) Pathophysiology and management of opioid‐induced constipation: European expert consensus statement. United European Gastroenterology Journal 7:1, pages 7-20.
Crossref
Crossref
Salman Nusrat, Taseen Syed, Rabia Saleem, Shari Clifton & Klaus Bielefeldt. (2018) Pharmacological Treatment of Opioid-Induced Constipation Is Effective but Choice of Endpoints Affects the Therapeutic Gain. Digestive Diseases and Sciences 64:1, pages 39-49.
Crossref
Crossref
Jasper Pannemans, Tim Vanuytsel & Jan Tack. (2018) New developments in the treatment of opioid‐induced gastrointestinal symptoms. United European Gastroenterology Journal 6:8, pages 1126-1135.
Crossref
Crossref
Judy Nee, Mohammed Zakari, Michael A. Sugarman, Julia Whelan, William Hirsch, Shahnaz Sultan, Sarah Ballou, Johanna Iturrino & Anthony Lembo. (2018) Efficacy of Treatments for Opioid-Induced Constipation: Systematic Review and Meta-analysis. Clinical Gastroenterology and Hepatology 16:10, pages 1569-1584.e2.
Crossref
Crossref
Dan Turner, Frank M. Ruemmele, Esther Orlanski-Meyer, Anne M. Griffiths, Javier Martin de Carpi, Jiri Bronsky, Gabor Veres, Marina Aloi, Caterina Strisciuglio, Christian P. Braegger, Amit Assa, Claudio Romano, Séamus Hussey, Michael Stanton, Mikko Pakarinen, Lissy de Ridder, Konstantinos H. Katsanos, Nick Croft, Víctor Manuel Navas-López, David C. Wilson, Sally Lawrence & Richard K. Russell. (2018) Management of Paediatric Ulcerative Colitis, Part 2: Acute Severe Colitis—An Evidence-based Consensus Guideline From the European Crohn's and Colitis Organization and the European Society of Paediatric Gastroenterology, Hepatology and Nutrition. Journal of Pediatric Gastroenterology & Nutrition 67:2, pages 292-310.
Crossref
Crossref
Bart J. Morlion, Stefan A. Mueller‐Lissner, Renato Vellucci, Wojciech Leppert, Benoît C. Coffin, Sara L. Dickerson & Tony O'Brien. (2017) Oral Prolonged‐Release Oxycodone/Naloxone for Managing Pain and Opioid‐Induced Constipation: A Review of the Evidence. Pain Practice 18:5, pages 647-665.
Crossref
Crossref
J. Nee, V. Rangan & A. Lembo. (2018) Reduction in pain: Is it worth the gain? The effect of opioids on the GI tract. Neurogastroenterology & Motility 30:5, pages e13367.
Crossref
Crossref
Chang Ju HwangSung Soo ChungKyu-Yeol LeeJae Hyup LeeSeong-Hwan MoonJin-Hyok KimKyu-Jung ChoJae-Sung AhnDong-Soo KimYe-Soo ParkHye-Jeong Park. (2018) Analgesic Efficacy and Safety of Prolonged-Release Oxycodone/Naloxone in Korean Patients with Chronic Pain from Spinal Disorders. Clinics in Orthopedic Surgery 10:1, pages 33.
Crossref
Crossref
. 2018. Arzneimitteltherapie in der Palliativmedizin. Arzneimitteltherapie in der Palliativmedizin
447
696
.
Esther S. Kim. (2017) Oxycodone/Naloxone Prolonged Release: A Review in Severe Chronic Pain. Clinical Drug Investigation 37:12, pages 1191-1201.
Crossref
Crossref
Lang Huang, Jian-Guo Zhou, Yu Zhang, Fei Wang, Yi Wang, Da-Hai Liu, Xin-Juan Li, Shui-Ping Lv, Su-Han Jin, Yu-Ju Bai & Hu Ma. (2017) Opioid-Induced Constipation Relief From Fixed-Ratio Combination Prolonged-Release Oxycodone/Naloxone Compared With Oxycodone and Morphine for Chronic Nonmalignant Pain: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Journal of Pain and Symptom Management 54:5, pages 737-748.e3.
Crossref
Crossref
D. Dupoiron, A. Stachowiak, O. Loewenstein, A. Ellery, W. Kremers, B. Bosse & M. Hopp. (2017) A phase III randomized controlled study on the efficacy and improved bowel function of prolonged-release (PR) oxycodone-naloxone (up to 160/80 mg daily) vs oxycodone PR. European Journal of Pain 21:9, pages 1528-1537.
Crossref
Crossref
D. Dupoiron, A. Stachowiak, O. Loewenstein, A. Ellery, W. Kremers, B. Bosse & M. Hopp. (2017) Long-term efficacy and safety of oxycodone-naloxone prolonged-release formulation (up to 180/90 mg daily) - results of the open-label extension phase of a phase III multicenter, multiple-dose, randomized, controlled study. European Journal of Pain 21:9, pages 1485-1494.
Crossref
Crossref
Michael Camilleri, Anthony Lembo & David A. Katzka. (2017) Opioids in Gastroenterology: Treating Adverse Effects and Creating Therapeutic Benefits. Clinical Gastroenterology and Hepatology 15:9, pages 1338-1349.
Crossref
Crossref
Jung Hoon Kim, Haana Song, Gyeong-Won Lee & Jung Hun Kang. (2017) Opioid Withdrawal Symptoms after Conversion to Oral Oxycodone/Naloxone in Advanced Cancer Patients Receiving Strong Opioids. The Korean Journal of Hospice and Palliative Care 20:2, pages 131-135.
Crossref
Crossref
Magdalena Kocot-KępskaRenata ZajączkowskaAnna Przeklasa-MuszyńskaJan Dobrogowski. (2017) The role of oxycodone/naloxone in pain management. BÓL 17:4, pages 26-40.
Crossref
Crossref
T. O'Brien, L.L. Christrup, A.M. Drewes, M.T. Fallon, H.G. Kress, H.J. McQuay, G. Mikus, B.J. Morlion, J. Perez-Cajaraville, E. Pogatzki-Zahn, G. Varrassi & J.C.D. Wells. (2017) European Pain Federation position paper on appropriate opioid use in chronic pain management. European Journal of Pain 21:1, pages 3-19.
Crossref
Crossref
Stefan Müller-Lissner, Gabrio Bassotti, Benoit Coffin, Asbjørn Mohr Drewes, Harald Breivik, Elon Eisenberg, Anton Emmanuel, Françoise Laroche, Winfried Meissner & Bart Morlion. (2016) Opioid-Induced Constipation and Bowel Dysfunction: A Clinical Guideline. Pain Medicine, pages pnw255.
Crossref
Crossref
Frida Hjalte, Gunnel Ragnarson Tennvall, Karl-Olof Welin & Dagmar Westerling. (2016) Treatment of Severe Pain and Opioid-induced Constipation: An Observational Study of Quality of Life, Resource Use, and Costs in Sweden. Pain and Therapy 5:2, pages 227-236.
Crossref
Crossref
Helen Gaskell, Sheena Derry, Cathy Stannard & R Andrew Moore. (2016) Oxycodone for neuropathic pain in adults. Cochrane Database of Systematic Reviews 2016:7.
Crossref
Crossref
Nalini Vadivelu, Erika Schermer, Gopal Kodumudi & Jack M. Berger. (2016) The Clinical Applications of Extended-Release Abuse-Deterrent Opioids. CNS Drugs 30:7, pages 637-646.
Crossref
Crossref
Karin S. Coyne, Chris Sexton, Robert J. LoCasale, Frederic R. King, Mary Kay Margolis & Sam H. Ahmedzai. (2016) Opioid-Induced Constipation among a Convenience Sample of Patients with Cancer Pain. Frontiers in Oncology 6.
Crossref
Crossref
Gareth P. Jones & Shiva S. Tripathi. (2016) Oxycodone and Naloxone Combination: A 12-Week Follow-up in 20 Patients Shows Effective Analgesia Without Opioid-Induced Bowel Dysfunction. Pain and Therapy 5:1, pages 107-113.
Crossref
Crossref
Asbjørn M. Drewes, Pia Munkholm, Magnus Simrén, Harald Breivik, Ulf E. Kongsgaard, Jan G. Hatlebakk, Lars Agreus, Maria Friedrichsen & Lona L. Christrup. (2016) Definition, diagnosis and treatment strategies for opioid-induced bowel dysfunction–Recommendations of the Nordic Working Group. Scandinavian Journal of Pain 11:1, pages 111-122.
Crossref
Crossref
Alfred D. Nelson & Michael Camilleri. (2016) Opioid-induced constipation: advances and clinical guidance. Therapeutic Advances in Chronic Disease 7:2, pages 121-134.
Crossref
Crossref
Shareen A. Iqbal, Joshua D. Wallach, Muin J. Khoury, Sheri D. Schully & John P. A. Ioannidis. (2016) Reproducible Research Practices and Transparency across the Biomedical Literature. PLOS Biology 14:1, pages e1002333.
Crossref
Crossref
Michael G. O’Neil & Justin G. Kullgren. 2016. A Worldwide Yearly Survey of New Data in Adverse Drug Reactions. A Worldwide Yearly Survey of New Data in Adverse Drug Reactions
71
76
.
Charles E. Argoff, Michael J. Brennan, Michael Camilleri, Andrew Davies, Jeffrey Fudin, Katherine E. Galluzzi, Jeffrey Gudin, Anthony Lembo, Steven P. Stanos & Lynn R. Webster. (2015) Consensus Recommendations on Initiating Prescription Therapies for Opioid-Induced Constipation. Pain Medicine 16:12, pages 2324-2337.
Crossref
Crossref
Claudia Trenkwalder, K Ray Chaudhuri, Pablo Martinez-Martin, Olivier Rascol, Reinhard Ehret, Martin Vališ, Maria Sátori, Anna Krygowska-Wajs, Maria J Marti, Karen Reimer, Alexander Oksche, Mark Lomax, Julia DeCesare & Michael Hopp. (2015) Prolonged-release oxycodone–naloxone for treatment of severe pain in patients with Parkinson's disease (PANDA): a double-blind, randomised, placebo-controlled trial. The Lancet Neurology 14:12, pages 1161-1170.
Crossref
Crossref
Mellar Davis & Pamela Gamier. (2015) New Options in Constipation Management. Current Oncology Reports 17:12.
Crossref
Crossref
Jakob Lykke Poulsen, Christina Brock, Anne Estrup Olesen, Matias Nilsson & Asbjørn Mohr Drewes. (2015) Evolving paradigms in the treatment of opioid-induced bowel dysfunction. Therapeutic Advances in Gastroenterology 8:6, pages 360-372.
Crossref
Crossref
MA Ueberall. (2015) Differential Gastrointestinal Effects of Who-Step III Opioids in Low Back Pain Patients with vs. Without Constipation: Post-Hoc Analysis of Data from a 12-Week Prospective, Open-Label Blinded Endpoint Streamlined Study. Global Journal of Anesthesiology, pages 037-051.
Crossref
Crossref
Graziella Madeo, Tommaso Schirinzi, Silvia Natoli, Mariangela Pierantozzi, Alessandro Stefani, Mario Dauri & Antonio Pisani. (2015) Efficacy and safety profile of prolonged release oxycodone in combination with naloxone (OXN PR) in Parkinson’s disease patients with chronic pain. Journal of Neurology 262:9, pages 2164-2170.
Crossref
Crossref
Adeleke Afolayan Joel, Iyabo Oyeleye Deborah, Omowumi Adebiyi Falilat, Omowumi Durojaiye Abiola & Bitrus Donald. (2015) Factors influencing perception of pain among clients attending a Nigeria teaching hospital. International Journal of Nursing and Midwifery 7:8, pages 133-140.
Crossref
Crossref
Alfred D. Nelson & Michael Camilleri. (2015) Chronic opioid induced constipation in patients with nonmalignant pain: challenges and opportunities. Therapeutic Advances in Gastroenterology 8:4, pages 206-220.
Crossref
Crossref
Borja Mugabure Bujedo. (2015) Treatment of Failed Back Surgery Syndrome in a Forty-Three-Year-Old Man With High-Dose Oxycodone/Naloxone. Anesthesiology and Pain Medicine 5:2.
Crossref
Crossref
Jan Poelaert, Gineke Koopmans-Klein, Alioune Dioh, Frédéric Louis, Mayken Gorissen, David Logé, Joeri Van Op den bosch & Yvonne J.B. van Megen. (2015) Treatment With Prolonged-Release Oxycodone/Naloxone Improves Pain Relief and Opioid-Induced Constipation Compared With Prolonged-Release Oxycodone in Patients With Chronic Severe Pain and Laxative-Refractory Constipation. Clinical Therapeutics 37:4, pages 784-792.
Crossref
Crossref
Sam H. Ahmedzai, Wojciech Leppert, Marcin Janecki, Artur Pakosz, Mark Lomax, Heike Duerr & Michael Hopp. (2014) Long-term safety and efficacy of oxycodone/naloxone prolonged-release tablets in patients with moderate-to-severe chronic cancer pain. Supportive Care in Cancer 23:3, pages 823-830.
Crossref
Crossref
Deepika Thakur, Sara Dickerson, Mohit Kumar Bhutani & Rod Junor. (2015) Impact of Prolonged-release Oxycodone/Naloxone on Outcomes Affecting Patients' Daily Functioning in Comparison With Extended-release Tapentadol: A Systematic Review. Clinical Therapeutics 37:1, pages 212-224.
Crossref
Crossref
. 2015. Arzneimitteltherapie in der Palliativmedizin. Arzneimitteltherapie in der Palliativmedizin
417
651
.
Bart Morlion, Katri Elina Clemens & Will Dunlop. (2014) Quality of Life and Healthcare Resource in Patients Receiving Opioids for Chronic Pain: A Review of the Place of Oxycodone/Naloxone. Clinical Drug Investigation 35:1, pages 1-11.
Crossref
Crossref
Jana Jeyakumar & David J. Feuer. 2015. Urological Oncology. Urological Oncology
311
322
.
Arturo Cuomo, Gennaro Russo, Gennaro Esposito, Cira Antonietta Forte, Marianna Connola & Claudio Marcassa. (2013) Efficacy and Gastrointestinal Tolerability of Oral Oxycodone/Naloxone Combination for Chronic Pain in Outpatients With Cancer. American Journal of Hospice and Palliative Medicine® 31:8, pages 867-876.
Crossref
Crossref
M. Blagden, J. Hafer, H. Duerr, M. Hopp & B. Bosse. (2014) Long‐term evaluation of combined prolonged‐release oxycodone and naloxone in patients with moderate‐to‐severe chronic pain: pooled analysis of extension phases of two Phase III trials. Neurogastroenterology & Motility 26:12, pages 1792-1801.
Crossref
Crossref
Michael Zimmermann & Ute Richarz. (2014) End-of-Dose Pain in Chronic Pain: Does it Vary with the Use of Different Long-Acting Opioids?. Pain Practice 14:8, pages 757-769.
Crossref
Crossref
V. C. P. C. Dongen, P. J. L. Vanelderen, G. Koopmans‐Klein, Y. J. B. Megen, J. Van Zundert & F. J. P. M. Huygen. (2014)
Patient preference with respect to QoL and reduction in opioid‐induced constipation (
OIC
) after treatment with prolonged‐release (
PR
) oxycodone/naloxone compared with previous analgesic therapy [
PREFER
study]
. International Journal of Clinical Practice 68:11, pages 1364-1375.
Crossref
Crossref
Eva Szigethy, Marc Schwartz & Douglas Drossman. (2014) Narcotic Bowel Syndrome and Opioid-Induced Constipation. Current Gastroenterology Reports 16:10.
Crossref
Crossref
Helen Gaskell, R Andrew Moore, Sheena Derry & Cathy Stannard. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
Anne Z. DePriest & Katie Miller. (2014) Oxycodone/Naloxone: Role in Chronic Pain Management, Opioid-Induced Constipation, and Abuse Deterrence. Pain and Therapy 3:1, pages 1-15.
Crossref
Crossref
Sabine Hesselbarth, Oliver Löwenstein & Thomas Cegla. (2014) Effects of prolonged-release oxycodone/naloxone on pain control, bowel function and quality of life: A prospective observational study. Scandinavian Journal of Pain 5:2, pages 75-81.
Crossref
Crossref
Celeste B. Burness & Gillian M. Keating. (2014) Oxycodone/Naloxone Prolonged-Release: A Review of Its Use in the Management of Chronic Pain While Counteracting Opioid-Induced Constipation. Drugs 74:3, pages 353-375.
Crossref
Crossref
Lalit Kumar, Chris Barker & Anton Emmanuel. (2014) Opioid-Induced Constipation: Pathophysiology, Clinical Consequences, and Management. Gastroenterology Research and Practice 2014, pages 1-6.
Crossref
Crossref
R. Viganò, A. Fanelli, D. Ghisi, G. Danelli & S. E. De Martinis. (2013) Il controllo del dolore nelle protesi totali di ginocchioManagement of pain after total knee replacement. LO SCALPELLO-OTODI Educational 27:3, pages 147-152.
Crossref
Crossref
Alexander C Ford, Darren M Brenner & Philip S Schoenfeld. (2013) Efficacy of Pharmacological Therapies for the Treatment of Opioid-Induced Constipation: Systematic Review and Meta-Analysis. American Journal of Gastroenterology 108:10, pages 1566-1574.
Crossref
Crossref
M. COMELON, K. WISLOEFF-AASE, J. RAEDER, T. DRAEGNI, H. UNDERSRUD, E. QVIGSTAD, C. E. BJERKELUND & H. LENZ. (2013) A comparison of oxycodone prolonged-release vs. oxycodone + naloxone prolonged-release after laparoscopic hysterectomy. Acta Anaesthesiologica Scandinavica 57:4, pages 509-517.
Crossref
Crossref
Jan Gaertner & Christine Schiessl. (2013) Cancer Pain Management: What’s New?. Current Pain and Headache Reports 17:4.
Crossref
Crossref
Antonio Gatti, Manuela Casali, Marzia Lazzari, Giuseppe Tufaro, Paolo Gafforio, Claudia Silvestri, Claudio Marcassa & Alessandro F. Sabato. (2012) Prolonged-Release Oxycodone/Naloxone in Nonmalignant Pain: Single-Center Study in Patients with Constipation. Advances in Therapy 30:1, pages 41-59.
Crossref
Crossref
Pascale Vergne-Salle, Françoise Laroche, Anne Bera-Louville, Marc Marty, Rose-Marie Javier & Serge Perrot. (2012) Les opioïdes forts dans les douleurs ostéo-articulaires non cancéreuses : revue de la littérature et recommandations pour la pratique clinique : « Les recommandations de Limoges 2010 ». Douleurs : Evaluation - Diagnostic - Traitement 13:6, pages 259-275.
Crossref
Crossref
F. Hoffmann, G. Glaeske & R. Windt. (2012) Verordnung von starken Opioiden im Jahr 2011Prescription of high-potency opioids in 2011. Der Schmerz 26:6, pages 707-714.
Crossref
Crossref
K Kuusniemi, J Zöllner, S Sjövall, J Huhtala, P Karjalainen, M Kokki, J Lemken, J Oppermann & H Kokki. (2012) Prolonged-release Oxycodone/Naloxone in Postoperative Pain Management: From a Randomized Clinical Trial to Usual Clinical Practice. Journal of International Medical Research 40:5, pages 1775-1793.
Crossref
Crossref
Christian Compagnone, Fernanda Tagliaferri & Andrea Ramelli. (2011) Some concerns about the article: "High doses of oxycodone–naloxone combination may provide poor analgesia.". Supportive Care in Cancer 20:5, pages 889-890.
Crossref
Crossref
Gálvez Rafael, Provencio Mariano, Sanz-Ortiz Jaime, Ribera Ma Victoria, Esteban Emilio, Collado Francisco, Vara Francisco, Díaz Pilar, Rocafort Javier, Cobo Manuel, Traseira Susana & Brosa Max. (2013) Análisis económico de oxicodona LP/ naloxona LP en el manejo del dolor intenso y el estreñimiento asociado al tratamiento con opioides en España. PharmacoEconomics Spanish Research Articles 9:1, pages 23-34.
Crossref
Crossref
Sam H Ahmedzai, Friedemann Nauck, Gil Bar-Sela, Björn Bosse, Petra Leyendecker & Michael Hopp. (2011) A randomized, double-blind, active-controlled, double-dummy, parallel-group study to determine the safety and efficacy of oxycodone/naloxone prolonged-release tablets in patients with moderate/severe, chronic cancer pain. Palliative Medicine 26:1, pages 50-60.
Crossref
Crossref
Bernhard Hess, Marco Bernardi & Hans-Peter Klotz. (2011) Attitude of Swiss physicians towards opioid-induced constipation: A national survey. European Journal of Internal Medicine 22:5, pages 527-531.
Crossref
Crossref
K. E. Clemens, I. Quednau & E. Klaschik. (2011) Bowel function during pain therapy with oxycodone/naloxone prolonged-release tablets in patients with advanced cancer. International Journal of Clinical Practice 65:4, pages 472-478.
Crossref
Crossref
Dan Turner, Simon P L Travis, Anne M Griffiths, Frank M Ruemmele, Arie Levine, Eric I Benchimol, Marla Dubinsky, George Alex, Robert N Baldassano, Jacob C Langer, Robert Shamberger, Jeffrey S Hyams, Salvatore Cucchiara, Athos Bousvaros, Johanna C Escher, James Markowitz, David C Wilson, Gert van Assche & Richard K Russell. (2011) Consensus for Managing Acute Severe Ulcerative Colitis in Children: A Systematic Review and Joint Statement From ECCO, ESPGHAN, and the Porto IBD Working Group of ESPGHAN. American Journal of Gastroenterology 106:4, pages 574-588.
Crossref
Crossref
MA Ueberall, S Müller-Lissner, C Buschmann-Kramm & B Bosse. (2011) The Bowel Function Index for Evaluating Constipation in Pain Patients: Definition of a Reference Range for a Non-Constipated Population of Pain Patients. Journal of International Medical Research 39:1, pages 41-50.
Crossref
Crossref
Oliver Löwenstein, Petra Leyendecker, Eberhard A Lux, Mark Blagden, Karen H Simpson, Michael Hopp, Björn Bosse & Karen Reimer. (2010) Efficacy and safety of combined prolonged-release oxycodone and naloxone in the management of moderate/severe chronic non-malignant pain: results of a prospectively designed pooled analysis of two randomised, double-blind clinical trials. BMC Clinical Pharmacology 10:1.
Crossref
Crossref
. (2010) Current World Literature. Current Opinion in Anaesthesiology 23:5, pages 671-678.
Crossref
Crossref
Peter Holzer. (2010) Opioid antagonists for prevention and treatment of opioid-induced gastrointestinal effects. Current Opinion in Anaesthesiology 23:5, pages 616-622.
Crossref
Crossref
Wojciech Leppert. (2010) The role of opioid receptor antagonists in the treatment of opioid-induced constipation: a review. Advances in Therapy 27:10, pages 714-730.
Crossref
Crossref
Stefan Mueller-Lissner. (2010) Fixed combination of oxycodone with naloxone: a new way to prevent and treat opioid-induced constipation. Advances in Therapy 27:9, pages 581-590.
Crossref
Crossref
N. Béziaud, J.-M. Pellat, V. Granger & M. Baudrant-Boga. (2010) Antagonistes opioïdes et constipationOpioids antagonists and constipation. Douleur et Analgésie 23:3, pages 182-188.
Crossref
Crossref
Wojciech Leppert. (2010) Role of oxycodone and oxycodone/naloxone in cancer pain management. Pharmacological Reports 62:4, pages 578-591.
Crossref
Crossref
A. Sandner-Kiesling, P. Leyendecker, M. Hopp, L. Tarau, J. Lejcko, W. Meissner, P. Sevcik, M. Hakl, R. Hrib, R. Uhl, H. Dürr & K. Reimer. (2010) Long-term efficacy and safety of combined prolonged-release oxycodone and naloxone in the management of non-cancer chronic pain. International Journal of Clinical Practice 64:6, pages 763-774.
Crossref
Crossref
Winfried Meissner, Müller‐Lissner, Joachim Nadstawek, Michael Hopp, Christian Ruckes, Stefan Wirz, Wolfgang Fleischer, Karen Reimer & Petra Leyendecker. (2012) Dr. Meissner and colleagues reply to the Letter to the Editor from Andrew Wilcock entitled ‘Prolonged‐release naloxone can cause systemic opioid withdrawal’. European Journal of Pain 13:9, pages 1002-1003.
Crossref
Crossref
Florentin Clère. (2009) Constipation induite par les opioïdes : état des lieux et nouvelles approches. Douleurs : Evaluation - Diagnostic - Traitement 10:5, pages 237-243.
Crossref
Crossref
Howard S Smith. (2009) Future of minimizing opioid adverse effects while maintaining or improving opioid-related analgesia. Therapy 6:5, pages 667-683.
Crossref
Crossref
D. Rothstein & M. Zenz. (2009) Therapie chronischer SchmerzenChronic pain management. Der Internist 50:9, pages 1161-1168.
Crossref
Crossref