272
Views
61
CrossRef citations to date
0
Altmetric
Review

Yeast whole glucan particle (WGP) β-glucan in conjunction with antitumour monoclonal antibodies to treat cancer

, &
Pages 691-702 | Published online: 24 Nov 2005

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Mei Zhang, Liane Chun, Victor Sandoval, Hallie Graor, Jay Myers, Joseph Nthale, Peter Rauhe, Zachary Senders, Kevin Choong, Alex Y. Huang & Julian Kim. (2018) Systemic administration of β-glucan of 200 kDa modulates melanoma microenvironment and suppresses metastatic cancer. OncoImmunology 7:2.
Read now
Joanna Saluk-Juszczak, Karolina Krolewska & Barbara Wachowicz. (2010) β-glucan from Saccharomyces cerevisiae as a blood platelet antioxidant. Platelets 21:6, pages 451-459.
Read now
S. Soltanian, E. Stuyven, E. Cox, P. Sorgeloos & P. Bossier. (2009) Beta-glucans as immunostimulant in vertebrates and invertebrates. Critical Reviews in Microbiology 35:2, pages 109-138.
Read now
Vaclav Vetvicka & Jana Vetvickova. (2009) Effects of yeast-derived β-glucans on blood cholesterol and macrophage functionality. Journal of Immunotoxicology 6:1, pages 30-35.
Read now
Olav Albert Christophersen & Anna Haug. (2007) More about hypervirulent avian influenza: Is the world now better prepared?. Microbial Ecology in Health and Disease 19:2, pages 78-121.
Read now
Kyra A Gelderman, Suzanne Lam & Arko Gorter. (2005) Inhibiting complement regulators in cancer immunotherapy with bispecific mAbs. Expert Opinion on Biological Therapy 5:12, pages 1593-1601.
Read now

Articles from other publishers (55)

Xuemei Zhong, Guoqing Wang, Fu Li, Sixian Fang, Siai Zhou, Akihiro Ishiwata, Alexander G. Tonevitsky, Maxim Shkurnikov, Hui Cai & Feiqing Ding. (2023) Immunomodulatory Effect and Biological Significance of β-Glucans. Pharmaceutics 15:6, pages 1615.
Crossref
Lydia Kalafati, Aikaterini Hatzioannou, George Hajishengallis & Triantafyllos Chavakis. (2022) The role of neutrophils in trained immunity. Immunological Reviews 314:1, pages 142-157.
Crossref
Yalan Deng, Liqing Lu, Huajun Zhang, Ying Fu, Ting Liu & Yongheng Chen. (2023) The role and regulation of Maf proteins in cancer. Biomarker Research 11:1.
Crossref
Shiu-Nan Chen, Fan-Hua Nan, Ming-Wei Liu, Min-Feng Yang, Ya-Chih Chang & Sherwin Chen. (2023) Evaluation of Immune Modulation by β-1,3; 1,6 D-Glucan Derived from Ganoderma lucidum in Healthy Adult Volunteers, A Randomized Controlled Trial. Foods 12:3, pages 659.
Crossref
Sulaiman Binmama, Cong Phi Dang, Peerapat Visitchanakun, Pratsanee Hiengrach, Naraporn Somboonna, Thanya Cheibchalard, Prapaporn Pisitkun, Ariya Chindamporn & Asada Leelahavanichkul. (2022) Beta-Glucan from S. cerevisiae Protected AOM-Induced Colon Cancer in cGAS-Deficient Mice Partly through Dectin-1-Manipulated Macrophage Cell Energy. International Journal of Molecular Sciences 23:18, pages 10951.
Crossref
Ya‐Wen Lo, Alan Yueh‐Luen Lee, Yi‐Ching Liu, Hui‐Hsin Ko, Hsin‐Hui Peng, Hsiang‐Chieh Lee, Pei‐Yao Pan, Chun‐Pin Chiang & Shih‐Jung Cheng. (2021) β‐glucan therapy converts the inhibition of myeloid‐derived suppressor cells in oral cancer patients. Oral Diseases 28:6, pages 1484-1495.
Crossref
Pratsanee Hiengrach, Peerapat Visitchanakun, Malcolm A. Finkelman, Wiwat Chancharoenthana & Asada Leelahavanichkul. (2022) More Prominent Inflammatory Response to Pachyman than to Whole-Glucan Particle and Oat-β-Glucans in Dextran Sulfate-Induced Mucositis Mice and Mouse Injection through Proinflammatory Macrophages. International Journal of Molecular Sciences 23:7, pages 4026.
Crossref
Natthaporn Chotigavin, Wiramsri Sriphochanart, Surachai Yaiyen & Sanya Kudan. (2021) Increasing the Production of β-Glucan from Saccharomyces carlsbergensis RU01 by Using Tannic Acid. Applied Biochemistry and Biotechnology 193:8, pages 2591-2601.
Crossref
Ionut Avramia & Sonia Amariei. (2021) Spent Brewer’s Yeast as a Source of Insoluble β-Glucans. International Journal of Molecular Sciences 22:2, pages 825.
Crossref
Roshanak Sambrani, Jalal Abdolalizadeh, Leila Kohan & Behboud Jafari. (2021) Recent advances in the application of probiotic yeasts, particularly Saccharomyces, as an adjuvant therapy in the management of cancer with focus on colorectal cancer. Molecular Biology Reports 48:1, pages 951-960.
Crossref
Ashok Patidar, Trishna Mahanty, Chandan Raybarman, Aditya Y. Sarode, Surajit Basak, Bhaskar Saha & Surajit Bhattacharjee. (2020) Barley beta‐Glucan and Zymosan induce Dectin‐1 and Toll‐like receptor 2 co‐localization and anti‐leishmanial immune response in Leishmania donovani ‐infected BALB/c mice . Scandinavian Journal of Immunology 92:6.
Crossref
Wenqian Li, Haomin Wang, Xiaoji G. Xu & Yan Yu. (2020) Simultaneous Nanoscale Imaging of Chemical and Architectural Heterogeneity on Yeast Cell Wall Particles. Langmuir 36:22, pages 6169-6177.
Crossref
Alice Tamburrini, Cinzia Colombo & Anna Bernardi. (2020) Design and synthesis of glycomimetics: Recent advances. Medicinal Research Reviews 40:2, pages 495-531.
Crossref
Ambreen Bano, Anmol Gupta, Swati Sharma & Rolee Sharma. 2020. Biogenic Nano-Particles and their Use in Agro-ecosystems. Biogenic Nano-Particles and their Use in Agro-ecosystems 371 391 .
Débora B. Scariot, Hélito Volpato, Nilma S. Fernandes, Danielle Lazarin-Bidóia, Olga Borges, Maria do Céu Sousa, Fernanda A. Rosa, Andrey P. Jacomini, Sueli O. Silva, Tânia Ueda-Nakamura, Adley F. Rubira & Celso V. Nakamura. (2019) Oral treatment with T6-loaded yeast cell wall particles reduces the parasitemia in murine visceral leishmaniasis model. Scientific Reports 9:1.
Crossref
Zuzana Plavcová, Petra Šalamúnová, Ivan Saloň, František Štěpánek, Jaroslav Hanuš & Jan Hošek. (2019) Curcumin encapsulation in yeast glucan particles promotes its anti-inflammatory potential in vitro. International Journal of Pharmaceutics 568, pages 118532.
Crossref
Xinxin Liu, Qixuan Lin, Yuhuan Yan, Feng Peng, Runcang Sun & Junli Ren. (2019) Hemicellulose from Plant Biomass in Medical and Pharmaceutical Application: A Critical Review. Current Medicinal Chemistry 26:14, pages 2430-2455.
Crossref
Débora Botura Scariot, Hélito Volpato, Nilma de Souza Fernandes, Edna Filipa Pais Soares, Tânia Ueda-Nakamura, Benedito Prado Dias-Filho, Zia Ud Din, Edson Rodrigues-Filho, Adley Forti Rubira, Olga Borges, Maria Do Céu Sousa & Celso Vataru Nakamura. (2019) Activity and Cell-Death Pathway in Leishmania infantum Induced by Sugiol: Vectorization Using Yeast Cell Wall Particles Obtained From Saccharomyces cerevisiae. Frontiers in Cellular and Infection Microbiology 9.
Crossref
Edna Soares, Zwier M.A. Groothuismink, André Boonstra & Olga Borges. (2019) Glucan Particles Are a Powerful Adjuvant for the HBsAg, Favoring Antiviral Immunity. Molecular Pharmaceutics 16:5, pages 1971-1981.
Crossref
Ehsan Ghaedi, Nima Rezaei & Maryam Mahmoudi. 2019. Nutrition and Immunity. Nutrition and Immunity 209 281 .
Xiaoxiao Liao, Václav Větvička & David Crich. (2018) Synthesis and Evaluation of 1,5-Dithia- d -laminaribiose, Triose, and Tetraose as Truncated β-(1→3)-Glucan Mimetics . The Journal of Organic Chemistry 83:24, pages 14894-14904.
Crossref
Yoko Ishida, Kouji Ohta, Takako Naruse, Hiroki Kato, Akiko Fukui, Hideo Shigeishi, Hiromi Nishi, Kei Tobiume & Masaaki Takechi. (2018) Candida albicans β-Glucan-Containing Particles Increase HO-1 Expression in Oral Keratinocytes via a Reactive Oxygen Species/p38 Mitogen-Activated Protein Kinase/Nrf2 Pathway. Infection and Immunity 86:4.
Crossref
Carlos Angulo, Erika Alamillo, Felipe Ascencio & Martha Reyes-Becerril. (2018) Characterization of nuclear factor of activated T-cells-c3 (NFATc3) and gene expression of upstream-downstream signaling molecules in response to immunostimulants in Pacific red snapper cells. Developmental & Comparative Immunology 78, pages 149-159.
Crossref
S.N. Chen, C.S. Chang, S. Chen & Madhu Soni. (2017) Subchronic toxicity and genotoxicity studies of Antrodia mushroom β-glucan preparation. Regulatory Toxicology and Pharmacology.
Crossref
Sawsan M Elsonbaty, Walid E Zahran & Fatma SM Moawed. (2017) Gamma-irradiated β-glucan modulates signaling molecular targets of hepatocellular carcinoma in rats. Tumor Biology 39:8, pages 101042831770870.
Crossref
Ashley R. Burg, Laura Quigley, Adam V. Jones, Geraldine M. O’Connor, Kimberly Boelte, Daniel W. McVicar & Selinda J. Orr. (2016) Orally administered β-glucan attenuates the Th2 response in a model of airway hypersensitivity. SpringerPlus 5:1.
Crossref
Ivan Saloň, Jaroslav Hanuš, Pavel Ulbrich & František Štěpánek. (2016) Suspension stability and diffusion properties of yeast glucan microparticles. Food and Bioproducts Processing 99, pages 128-135.
Crossref
Laurent Legentil, Franck Paris, Caroline Ballet, Sophie Trouvelot, Xavier Daire, Vaclav Vetvicka & Vincent Ferrières. (2015) Molecular Interactions of β-(1→3)-Glucans with Their Receptors. Molecules 20:6, pages 9745-9766.
Crossref
Wilsy Wilson, Douglas Lowman, Swapna P. Antony, Jayesh Puthumana, I.S. Bright Singh & Rosamma Philip. (2015) Immune gene expression profile of Penaeus monodon in response to marine yeast glucan application and white spot syndrome virus challenge. Fish & Shellfish Immunology 43:2, pages 346-356.
Crossref
Karl V. Clemons, Michael E. Danielson, Kyle S. Michel, Min Liu, Nadine C. Ottoson, Steven M. Leonardo, Marife Martinez, Vicky Chen, Mary A. Antonysamy & David A. Stevens. (2014) Whole glucan particles as a vaccine against murine aspergillosis. Journal of Medical Microbiology 63:12, pages 1750-1759.
Crossref
Angélique Ferry, Gaëlle Malik, Xavier Guinchard, Václav Vĕtvička & David Crich. (2014) Synthesis and Evaluation of Di- and Trimeric Hydroxylamine-Based β-(1→3)-Glucan Mimetics. Journal of the American Chemical Society 136:42, pages 14852-14857.
Crossref
Miroslav Veverka, Tibor Dubaj, Ján Gallovič, Vladimír Jorík, Eva Veverková, Matej Mičušík & Peter Šimon. (2014) Beta-glucan complexes with selected nutraceuticals: Synthesis, characterization, and stability. Journal of Functional Foods 8, pages 309-318.
Crossref
Sainkhuu Batbayar, Dong-Hee Lee & Ha-Won Kim. (2012) Immunomodulation of Fungal β-Glucan in Host Defense Signaling by Dectin-1. Biomolecules and Therapeutics 20:5, pages 433-445.
Crossref
Jan Fric, Teresa Zelante, Alicia Y. W. Wong, Alexandra Mertes, Hong-Bing Yu & Paola Ricciardi-Castagnoli. (2012) NFAT control of innate immunity. Blood 120:7, pages 1380-1389.
Crossref
S.N. Chen, F.H. Nan, S. Chen, J.F. Wu, C.L. Lu & Madhu G. Soni. (2011) Safety assessment of mushroom β-glucan: Subchronic toxicity in rodents and mutagenicity studies. Food and Chemical Toxicology 49:11, pages 2890-2898.
Crossref
Bret E. Betz, Abul K. Azad, Jessica D. Morris, Murugesan V.S. Rajaram & Larry S. Schlesinger. (2011) ?-Glucans inhibit intracellular growth of Mycobacterium bovis BCG but not virulent Mycobacterium tuberculosis in human macrophages. Microbial Pathogenesis 51:4, pages 233-242.
Crossref
Shinil K. Shah, Peter A. Walker, Stacey D. Moore-Olufemi, Alamelu Sundaresan, Anil D. Kulkarni & Richard J. Andrassy. (2011) An Evidence-Based Review of a Lentinula edodes Mushroom Extract as Complementary Therapy in the Surgical Oncology Patient . Journal of Parenteral and Enteral Nutrition 35:4, pages 449-458.
Crossref
Bing Li, Yihua Cai, Chunjian Qi, Richard Hansen, Chuanlin Ding, Thomas C. Mitchell & Jun Yan. (2010) Orally Administered Particulate β-Glucan Modulates Tumor-Capturing Dendritic Cells and Improves Antitumor T-Cell Responses in Cancer. Clinical Cancer Research 16:21, pages 5153-5164.
Crossref
Wangjian Zhong, Richard Hansen, Bing Li, Yihua Cai, Carolina Salvador, Grace D. Moore & Jun Yan. (2009) Effect of Yeast-derived β-glucan in Conjunction With Bevacizumab for the Treatment of Human Lung Adenocarcinoma in Subcutaneous and Orthotopic Xenograft Models. Journal of Immunotherapy 32:7, pages 703-712.
Crossref
Jingjing Liu, Lacey Gunn, Richard Hansen & Jun Yan. (2009) Combined yeast-derived ?-glucan with anti-tumor monoclonal antibody for cancer immunotherapy. Experimental and Molecular Pathology 86:3, pages 208-214.
Crossref
Gordon D. Brown & David L. Williams. 2009. Chemistry, Biochemistry, and Biology of 1-3 Beta Glucans and Related Polysaccharides. Chemistry, Biochemistry, and Biology of 1-3 Beta Glucans and Related Polysaccharides 579 619 .
Vaclav Vetvicka, Aruna Vashishta, Sujata Saraswat-Ohri & Jana Vetvickova. (2008) Immunological Effects of Yeast- and Mushroom-Derived β -Glucans . Journal of Medicinal Food 11:4, pages 615-622.
Crossref
John Milner & Elaine Trujillo. 2008. Handbook of Nutrition in the Aged, Fourth Edition. Handbook of Nutrition in the Aged, Fourth Edition 189 216 .
Alan B Weitberg. (2008) A phase I/II trial of beta-(1,3)/(1,6) D-glucan in the treatment of patients with advanced malignancies receiving chemotherapy. Journal of Experimental & Clinical Cancer Research 27:1.
Crossref
Daniel E. Cramer, Stephanie Wagner, Bing Li, Jingjing Liu, Richard Hansen, Ryan Reca, Wan Wu, Ewa Zuba Surma, Damian A. Laber, Mariusz Z. Ratajczak & Jun Yan. (2008) Mobilization of Hematopoietic Progenitor Cells by Yeast-Derived β -Glucan Requires Activation of Matrix Metalloproteinase-9 . Stem Cells 26:5, pages 1231-1240.
Crossref
Carolina Salvador, Bing Li, Richard Hansen, Daniel E. Cramer, Maiying Kong & Jun Yan. (2008) Yeast-Derived β-Glucan Augments the Therapeutic Efficacy Mediated by Anti–Vascular Endothelial Growth Factor Monoclonal Antibody in Human Carcinoma Xenograft Models. Clinical Cancer Research 14:4, pages 1239-1247.
Crossref
Jun Yan, Daniel J. Allendorf, Bing Li, Ruowan Yan, Richard Hansen & Rossen Donev. 2008. Current Topics in Complement II. Current Topics in Complement II 152 167 .
Masaki Imai, Rieko Ohta, Juan C. Varela, Hongbin Song & Stephen Tomlinson. (2007) Enhancement of Antibody-Dependent Mechanisms of Tumor Cell Lysis by a Targeted Activator of Complement. Cancer Research 67:19, pages 9535-9541.
Crossref
Bing Li, Daniel J. Allendorf, Richard Hansen, Jose Marroquin, Daniel E. Cramer, Claire L. Harris & Jun Yan. (2007) Combined Yeast β-Glucan and Antitumor Monoclonal Antibody Therapy Requires C5a-Mediated Neutrophil Chemotaxis via Regulation of Decay-Accelerating Factor CD55. Cancer Research 67:15, pages 7421-7430.
Crossref
Bing Li, Daniel Cramer, Stephanie Wagner, Richard Hansen, Chelsea King, Shelly Kakar, Chuanlin Ding & Jun Yan. (2007) Yeast glucan particles activate murine resident macrophages to secrete proinflammatory cytokines via MyD88- and Syk kinase-dependent pathways. Clinical Immunology 124:2, pages 170-181.
Crossref
Jiezhong Chen & Robert Seviour. (2007) Medicinal importance of fungal β-(1→3), (1→6)-glucans. Mycological Research 111:6, pages 635-652.
Crossref
Nadia Reyna-Villasmil, Valmore Bermúdez-Pirela, Edgardo Mengual-Moreno, Nelly Arias, Clímaco Cano-Ponce, Elliuz Leal-Gonzalez, Aida Souki, George E Inglett, Zafar H Israili, Rafael Hernández-Hernández, Manuel Valasco & Naikt Arraiz. (2007) Oat-derived β-Glucan Significantly Improves HDLC and Diminishes LDLC and Non-HDL Cholesterol in Overweight Individuals With Mild Hypercholesterolemia. American Journal of Therapeutics 14:2, pages 203-212.
Crossref
Marco Porcu, Francesco Guarna, Laura Formentini, Giuseppe Faraco, Silvia Fossati, Rita Mencucci, Emilio Rapizzi, Ugo Menchini, Flavio Moroni & Alberto Chiarugi. (2007) Carboxymethyl β-glucan Binds to Corneal Epithelial Cells and Increases Cell Adhesion to Laminin and Resistance to Oxidative Stress. Cornea 26:1, pages 73-79.
Crossref
Bing Li, Daniel J. Allendorf, Richard Hansen, Jose Marroquin, Chuanlin Ding, Daniel E. Cramer & Jun Yan. (2006) Yeast β-Glucan Amplifies Phagocyte Killing of iC3b-Opsonized Tumor Cells via Complement Receptor 3-Syk-Phosphatidylinositol 3-Kinase Pathway. The Journal of Immunology 177:3, pages 1661-1669.
Crossref
. (2006) Current awareness on yeast. Yeast 23:1, pages 67-74.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.