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Targeting the Fc receptor in autoimmune disease

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Karelle Ménochet, Hongbin Yu, Bonnie Wang, Jay Tibbitts, Cheng-Pang Hsu, Amrita V. Kamath, Wolfgang F. Richter & Andreas Baumann. (2022) Non-human primates in the PKPD evaluation of biologics: Needs and options to reduce, refine, and replace. A BioSafe White Paper. mAbs 14:1.
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Brian C. Mackness, Julie A. Jaworski, Ekaterina Boudanova, Anna Park, Delphine Valente, Christine Mauriac, Olivier Pasquier, Thorsten Schmidt, Mostafa Kabiri, Abdullah Kandira, Katarina Radošević & Huawei Qiu. (2019) Antibody Fc engineering for enhanced neonatal Fc receptor binding and prolonged circulation half-life. mAbs 11:7, pages 1276-1288.
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Gargi Roy, Tom Martin, Arnita Barnes, Jihong Wang, Rod Brian Jimenez, Megan Rice, Lina Li, Hui Feng, Shu Zhang, Raghothama Chaerkady, Herren Wu, Marcello Marelli, Diane Hatton, Jie Zhu & Michael A. Bowen. (2018) A novel bicistronic gene design couples stable cell line selection with a fucose switch in a designer CHO host to produce native and afucosylated glycoform antibodies. mAbs 10:3, pages 416-430.
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Divya Shankar, Giovanna Merchand-Reyes, Nathaniel J. Buteyn, Ramasamy Santhanam, Huiqing Fang, Krishan Kumar, Xiaokui Mo, Latha P. Ganesan, Wael Jarjour, Jonathan P. Butchar & Susheela Tridandapani. (2023) Inhibition of BET Proteins Regulates Fcγ Receptor Function and Reduces Inflammation in Rheumatoid Arthritis. International Journal of Molecular Sciences 24:8, pages 7623.
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Yuko Nakajima-Kato, Masato Komai, Tadashi Yoshida & Akiko Kanai. (2023) A novel monoclonal antibody with improved FcγR blocking ability demonstrated non-inferior efficacy compared to IVIG in cynomolgus monkey ITP model at considerably lower dose. Clinical and Experimental Immunology 211:1, pages 23-30.
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John S. Thompson, Alice C. Thornton, Timothy Ainger & Beth A. Garvy. (2023) Long-term high-dose immunoglobulin successfully treats Long COVID patients with pulmonary, neurologic, and cardiologic symptoms. Frontiers in Immunology 13.
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Anaïs Makos, J. H. Kuiper, O. Kehoe & R. Amarasena. (2022) Psoriatic arthritis: review of potential biomarkers predicting response to TNF inhibitors. Inflammopharmacology 31:1, pages 77-87.
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Sahar Abdel-Rahman Elsayed, Heba Maher Kamaly & Mohamed Ali Esmail. (2022) Co-positivity of anti-dsDNA, anti-nucleosome, and anti-smith autoantibodies as serological biomarkers for disease activity in systemic lupus erythematosus. Egyptian Rheumatology and Rehabilitation 49:1.
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Ion G. Motofei. (2022) Biology of cancer; from cellular and molecular mechanisms to developmental processes and adaptation. Seminars in Cancer Biology 86, pages 600-615.
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Saranya B Gomathy, Ayush Agarwal & Venugopalan Y Vishnu. (2022) Molecular Therapy in Myasthenia Gravis. Neurology 18:1, pages 49.
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Jinglan Jin, Yuwei Liu, Xiaotong Xu, Zhongfeng Wang & Junqi Niu. (2021) The association between Fc gamma RIIb expression levels and chronic hepatitis B virus infection progression. BMC Infectious Diseases 21:1.
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Roya Ramezankhani, Neda Minaei, Mahnaz Haddadi, Roya Solhi & Sara Taleahmad. (2021) The impact of sex on susceptibility to systemic lupus erythematosus and rheumatoid arthritis; a bioinformatics point of view. Cellular Signalling 88, pages 110171.
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Annalee W. Nguyen & Jennifer A. Maynard. 2021. Protein Engineering. Protein Engineering 317 351 .
Jin Kim, Ji Young Lee, Han Gil Kim, Min Woo Kwak & Tae Hyun Kang. (2021) Fc Receptor Variants and Disease: A Crucial Factor to Consider in the Antibody Therapeutics in Clinic. International Journal of Molecular Sciences 22:17, pages 9489.
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Pranay Bharadwaj & Margaret E. Ackerman. 2021. Antibody Glycosylation. Antibody Glycosylation 565 587 .
Katja Linher-Melville, Anita Shah & Gurmit Singh. (2020) Sex differences in neuro(auto)immunity and chronic sciatic nerve pain. Biology of Sex Differences 11:1.
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Deepak Menon, Carolina Barnett & Vera Bril. (2020) Novel Treatments in Myasthenia Gravis. Frontiers in Neurology 11.
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Justyna Gornowicz-Porowska, Michał J. Kowalczyk, Agnieszka Seraszek-Jaros, Monika Bowszyc-Dmochowska, Elżbieta Kaczmarek, Ryszard Żaba & Marian Dmochowski. (2020) A Comparative Analysis of CD32A and CD16A Polymorphisms in Relation to Autoimmune Responses in Pemphigus Diseases and Subepithelial Autoimmune Blistering Disorders. Genes 11:4, pages 371.
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Thamer A. Hamdan, Philipp A. Lang & Karl S. Lang. (2020) The Diverse Functions of the Ubiquitous Fcγ Receptors and Their Unique Constituent, FcRγ Subunit. Pathogens 9:2, pages 140.
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Bin Ma, Chaomin Li, Brian T. Hopkins, Lloyd Franklin, Robbie Chen, Tamera Mack, Daniel Patience, William F. Kiesman & Erin M. O’Brien. 2020. Complete Accounts of Integrated Drug Discovery and Development: Recent Examples from the Pharmaceutical Industry Volume 3. Complete Accounts of Integrated Drug Discovery and Development: Recent Examples from the Pharmaceutical Industry Volume 3 313 337 .
M. Eugenia Delgado & Thomas Brunner. (2019) The many faces of tumor necrosis factor signaling in the intestinal epithelium. Genes & Immunity 20:8, pages 609-626.
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Paola Cavalcante, Tehila Mizrachi, Claudia Barzago, Letizia Scandiffio, Federica Bortone, Silvia Bonanno, Rita Frangiamore, Renato Mantegazza, Pia Bernasconi, Talma Brenner, Adi Vaknin-Dembinsky & Carlo Antozzi. (2019) MicroRNA signature associated with treatment response in myasthenia gravis: a further step towards precision medicine. Pharmacological Research, pages 104388.
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Prakash Babu NarasimhanPaola MarcovecchioAnouk A.J. HamersCatherine C. Hedrick. (2019) Nonclassical Monocytes in Health and Disease. Annual Review of Immunology 37:1, pages 439-456.
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Elisabeth A. van Erp, Willem Luytjes, Gerben Ferwerda & Puck B. van Kasteren. (2019) Fc-Mediated Antibody Effector Functions During Respiratory Syncytial Virus Infection and Disease. Frontiers in Immunology 10.
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Jessica C. Anania, Alicia M. Chenoweth, Bruce D. Wines & P. Mark Hogarth. (2019) The Human FcγRII (CD32) Family of Leukocyte FcR in Health and Disease. Frontiers in Immunology 10.
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Kashyap R. Patel, Jacob T. Roberts & Adam W. Barb. (2019) Multiple Variables at the Leukocyte Cell Surface Impact Fc γ Receptor-Dependent Mechanisms. Frontiers in Immunology 10.
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Bo Chen, Katherine A Vousden, Brian Naiman, Sean Turman, Hong Sun, Shu Wang, Lisa M K Vinall, Benjamin P Kemp, Srinath Kasturiangan, D Gareth Rees, Ethan Grant, Mary Jane Hinrichs, Steven Eck, Antonio DiGiandomenico, M Jack Borrok, Neang Ly, Ximing Xiong, Carlos Gonzalez, Christopher Morehouse, Yue Wang, Yebin Zhou, Jennifer Cann, Weiguang Zhao, Holly Koelkebeck, Koshu Okubo, Tanya N Mayadas, David Howe, Janet Griffiths, Roland Kolbeck, Ronald Herbst & Gary P Sims. (2019) Humanised effector-null FcγRIIA antibody inhibits immune complex-mediated proinflammatory responses. Annals of the Rheumatic Diseases 78:2, pages 228-237.
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Elien Grajchen, Jerome J. A. Hendriks & Jeroen F. J. Bogie. (2018) The physiology of foamy phagocytes in multiple sclerosis. Acta Neuropathologica Communications 6:1.
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Tania F. Rowley, Shirley J. Peters, Mike Aylott, Robert Griffin, Nicola L. Davies, Louise J. Healy, Rona M. Cutler, Alison Eddleston, Thomas L. Pither, Joshua M. Sopp, Oliver Zaccheo, Gianluca Fossati, Katharine Cain, Andrew M. Ventom, Hanna Hailu, Eleanor J. Ward, John Sherington, Frank R. Brennan, Farnaz Fallah-Arani & David P. Humphreys. (2018) Engineered hexavalent Fc proteins with enhanced Fc-gamma receptor avidity provide insights into immune-complex interactions. Communications Biology 1:1.
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Yoshiki Nakamura, Kazumasa Yokoyama, Keiko Igaki & Noboru Tsuchimori. (2018) Role of Malt1 protease activity in pathogenesis of inflammatory disorders mediated by FcγR signaling. International Immunopharmacology 56, pages 193-196.
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Alan H. Lazarus. 2018. Antibody Therapy. Antibody Therapy 73 83 .
O. S. Qureshi, T. F. Rowley, F. Junker, S. J. Peters, S. Crilly, J. Compson, A. Eddleston, H. Björkelund, K. Greenslade, M. Parkinson, N. L. Davies, R. Griffin, T. L. Pither, K. Cain, L. Christodoulou, L. Staelens, E. Ward, J. Tibbitts, A. Kiessling, B. Smith, F. R. Brennan, M. Malmqvist, F. Fallah-Arani & D. P. Humphreys. (2017) Multivalent Fcγ-receptor engagement by a hexameric Fc-fusion protein triggers Fcγ-receptor internalisation and modulation of Fcγ-receptor functions. Scientific Reports 7:1.
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A Dokala & S S Thakur. (2016) Extracellular region of epidermal growth factor receptor: a potential target for anti-EGFR drug discovery. Oncogene 36:17, pages 2337-2344.
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Daniel F. OrtizJonathan C. LansingLaura RutitzkyElma KurtagicThomas Prod’hommeAmit ChoudhuryNathaniel WashburnNaveen BhatnagarChristopher BeneduceKimberly HolteRobert PrenovitzMatthew ChildJason KilloughSteven TylerJulia BrownStephanie NguyenInessa SchwabMaurice HainsRobin MeccarielloLynn MarkowitzJing WangRadouane ZouaouiAllison SimpsonBirgit SchultesIshan CapilaLeona LingFalk NimmerjahnAnthony M. ManningCarlos J. Bosques. (2016) Elucidating the interplay between IgG-Fc valency and FcγR activation for the design of immune complex inhibitors. Science Translational Medicine 8:365.
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R Salerno-Goncalves, F Safavie, A Fasano & M B Sztein. (2016) Free and complexed-secretory immunoglobulin A triggers distinct intestinal epithelial cell responses. Clinical and Experimental Immunology 185:3, pages 338-347.
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SunAh Kang, Jennifer L. Rogers, Andrew J. Monteith, Chuancang Jiang, John Schmitz, Stephen H. Clarke, Teresa K. Tarrant, Young K. Truong, Marilyn Diaz, Yuri Fedoriw & Barbara J. Vilen. (2016) Apoptotic Debris Accumulates on Hematopoietic Cells and Promotes Disease in Murine and Human Systemic Lupus Erythematosus. The Journal of Immunology 196:10, pages 4030-4039.
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Xing Li, Yanping Han & Erwei Sun. (2016) Sniping the scout: Targeting the key molecules in dendritic cell functions for treatment of autoimmune diseases. Pharmacological Research 107, pages 27-41.
Crossref
Barbara Dema & Nicolas Charles. (2016) Autoantibodies in SLE: Specificities, Isotypes and Receptors. Antibodies 5:1, pages 2.
Crossref
Mark H. Wener. 2016. Systemic Lupus Erythematosus. Systemic Lupus Erythematosus 223 229 .
T. Ernandez, G. Saggu & T.N. Mayadas. 2016. Systemic Lupus Erythematosus. Systemic Lupus Erythematosus 159 184 .
Shiang-Jong Tzeng, Wan-Yu Li & Hui-Ying Wang. (2015) Fc?RIIB mediates antigen-independent inhibition on human B lymphocytes through Btk and p38 MAPK. Journal of Biomedical Science 22:1.
Crossref
Shannon J. Beasley & Judith M. Greer. (2015) Autoantibodies and their potential roles in diseases of the nervous system. Clinical and Experimental Neuroimmunology 6:4, pages 370-386.
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Lijuan Guan, Loris Rizzello & Giuseppe Battaglia. (2015) Polymersomes and their applications in cancer delivery and therapy. Nanomedicine 10:17, pages 2757-2780.
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Masato Kiyoshi, Jose M.M. Caaveiro, Takeaki Kawai, Shinya Tashiro, Teruhiko Ide, Yoshiharu Asaoka, Kouta Hatayama & Kouhei Tsumoto. (2015) Structural basis for binding of human IgG1 to its high-affinity human receptor FcγRI. Nature Communications 6:1.
Crossref

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