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Editorial

Subcellular G-protein coupled receptor signaling hints at greater therapeutic selectivity

, MD PhD, & , MD PhD

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Vikrant K. Bhosle, José Carlos Rivera & Sylvain Chemtob. (2019) New insights into mechanisms of nuclear translocation of G-protein coupled receptors. Small GTPases 10:4, pages 254-263.
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Articles from other publishers (21)

Yuh‐Jiin I. Jong, Steven K. Harmon & Karen L. O'Malley. 2022. GPCRs as Therapeutic Targets. GPCRs as Therapeutic Targets 216 298 .
Kyle Pemberton, Martina Rosato, Cass Dedert, Chelsea DeLeon, Christopher Arnatt & Fenglian Xu. (2022) Differential Effects of the G-Protein-Coupled Estrogen Receptor (GPER) on Rat Embryonic (E18) Hippocampal and Cortical Neurons. eneuro 9:4, pages ENEURO.0475-21.2022.
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Guangchun Fan, Zhengxin Tao, Shang Chen, Huahua Zhang & Rongjie Yu. (2022) Positive allosteric regulation of PAC1-R up-regulates<?A3B2 ACK?>PAC1-R and its specific ligand PACAP. Acta Biochimica et Biophysica Sinica 54:5, pages 657-672.
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Olga A. Sukocheva, Dong Gui Hu, Robyn Meech & Anupam Bishayee. (2021) Divergence of Intracellular Trafficking of Sphingosine Kinase 1 and Sphingosine-1-Phosphate Receptor 3 in MCF-7 Breast Cancer Cells and MCF-7-Derived Stem Cell-Enriched Mammospheres. International Journal of Molecular Sciences 22:9, pages 4314.
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Mohammad Ali Mohammad Nezhady, José Carlos Rivera & Sylvain Chemtob. (2020) Location Bias as Emerging Paradigm in GPCR Biology and Drug Discovery. iScience 23:10, pages 101643.
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Xin Zhang, Shaohua Fan, Lihui Zhang & Yawei Shi. (2020) Glucagon‐like peptide‐1 receptor undergoes importin‐α‐dependent nuclear localization in rat aortic smooth muscle cells. FEBS Letters 594:10, pages 1506-1516.
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Surinder M. Soond & Andrey A. ZamyatninJr.Jr.. 2020. GPCR Signaling in Cancer. GPCR Signaling in Cancer 49 97 .
A. Aouiss, D. Anka Idrissi, M. Kabine & Y. Zaid. (2019) Update of inflammatory proliferative retinopathy: Ischemia, hypoxia and angiogenesis. Current Research in Translational Medicine 67:2, pages 62-71.
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Céléna Dubuc, Martin Savard, Veronica Bovenzi, Andrée Lessard, Jérôme Côté, Witold Neugebauer, Sameh Geha, Sylvain Chemtob & Fernand GobeilJr.Jr.. (2018) Antitumor activity of cell‐penetrant kinin B1 receptor antagonists in human triple‐negative breast cancer cells. Journal of Cellular Physiology 234:3, pages 2851-2865.
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Yuh-Jiin I Jong, Steven K Harmon & Karen L O'Malley. (2018) GPCR signalling from within the cell. British Journal of Pharmacology 175:21, pages 4026-4035.
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Yuh-Jiin I. Jong, Steven K. Harmon & Karen L. O’Malley. (2018) Intracellular GPCRs Play Key Roles in Synaptic Plasticity. ACS Chemical Neuroscience 9:9, pages 2162-2172.
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Muhammad M. Rahman, Allon Hazan, Joanne L. Selway, Dimalee S. Herath, Catherine A. Harwood, Muhammad S. Pirzado, Ravinder Atkar, David P. Kelsell, Kenneth J. Linton, Mike P. Philpott & Graham W. Neill. (2018) A Novel Mechanism for Activation of GLI1 by Nuclear SMO That Escapes Anti-SMO Inhibitors. Cancer Research 78:10, pages 2577-2588.
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Jean-Sébastien Joyal, Marin L. Gantner & Lois E.H. Smith. (2018) Retinal energy demands control vascular supply of the retina in development and disease: The role of neuronal lipid and glucose metabolism. Progress in Retinal and Eye Research 64, pages 131-156.
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Wenjing Wang, Yuhui Qiao & Zijian Li. (2018) New Insights into Modes of GPCR Activation. Trends in Pharmacological Sciences 39:4, pages 367-386.
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Céléna Dubuc, Martin Savard, Veronica Bovenzi, Andrée Lessard, Audrey Fortier, Jérôme Côté, Witold Neugebauer, Flavio Rizzolio, Sameh Geha, Antonio Giordano, Sylvain Chemtob & Fernand Gobeil. (2018) Targeting intracellular B2 receptors using novel cell-penetrating antagonists to arrest growth and induce apoptosis in human triple-negative breast cancer. Oncotarget 9:11, pages 9885-9906.
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Olga Sukocheva. (2018) Expansion of Sphingosine Kinase and Sphingosine-1-Phosphate Receptor Function in Normal and Cancer Cells: From Membrane Restructuring to Mediation of Estrogen Signaling and Stem Cell Programming. International Journal of Molecular Sciences 19:2, pages 420.
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Marco Pupo, Alexandre Bodmer, Melissa Berto, Marcello Maggiolini, Pierre-Yves Dietrich & Didier Picard. (2017) A genetic polymorphism repurposes the G-protein coupled and membrane-associated estrogen receptor GPER to a transcription factor-like molecule promoting paracrine signaling between stroma and breast carcinoma cells. Oncotarget 8:29, pages 46728-46744.
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Sathya Narayanan Patmanathan, Wei Wang, Lee Fah Yap, Deron R. Herr & Ian C. Paterson. (2017) Mechanisms of sphingosine 1-phosphate receptor signalling in cancer. Cellular Signalling 34, pages 66-75.
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Justyna M. Wierzbicka, Michał A. Żmijewski, Jakub Antoniewicz, Michal Sobjanek & Andrzej T. Slominski. (2017) Differentiation of Keratinocytes Modulates Skin HPA Analog. Journal of Cellular Physiology 232:1, pages 154-166.
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Vikrant K Bhosle, José Carlos Rivera, Tianwei Zhou, Samy Omri, Melanie Sanchez, David Hamel, Tang Zhu, Raphael Rouget, Areej Al Rabea, Xin Hou, Isabelle Lahaie, Alfredo Ribeiro-da-Silva & Sylvain Chemtob. (2016) Nuclear localization of platelet-activating factor receptor controls retinal neovascularization. Cell Discovery 2:1.
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Kimberly Regna, Peri T. Kurshan, Benjamin N. Harwood, Adam M. Jenkins, Chao-Qiang Lai, Marc A.T. Muskavitch, Alan S. Kopin & Isabelle Draper. (2016) A critical role for the Drosophila dopamine D1-like receptor Dop1R2 at the onset of metamorphosis. BMC Developmental Biology 16:1.
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