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Review

Review on the Structures and Activities of Transthyretin Amyloidogenesis Inhibitors

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Pages 1057-1081 | Published online: 10 Mar 2020

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Bin Zhong, Xianhua Huang, Yizhou Zheng, Xiaohua Guo & Longhuo Wu. (2021) The Discovery and Development of Transthyretin Amyloidogenesis Inhibitors: What are the Lessons?. Future Medicinal Chemistry 13:23, pages 2083-2105.
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Articles from other publishers (14)

Monali B. Patil, Piyush Ghode & Prashant Joshi. (2024) A Comprehensive Review on Chemistry and Biology of Tafamidis in Transthyretin Amyloidosis. Mini-Reviews in Medicinal Chemistry 24:6, pages 571-587.
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Vaishnavi Golatkar & Lokesh Kumar Bhatt. (2023) Emerging therapeutic avenues in cardiac amyloidosis. European Journal of Pharmacology 960, pages 176142.
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Lidia Ciccone, Caterina Camodeca, Nicolò Tonali, Lucia Barlettani, Armando Rossello, Carole Fruchart Gaillard, Julia Kaffy, Giovanni Petrarolo, Concettina La Motta, Susanna Nencetti & Elisabetta Orlandini. (2023) New Hybrid Compounds Incorporating Natural Products as Multifunctional Agents against Alzheimer’s Disease. Pharmaceutics 15:10, pages 2369.
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Seok Beom Lee, Jaeni Yu, Hyunwoo Kim, Kun Woo Kim, Jong Woo Jeong, Yun Lan Kim, Sung Jean Park, Tae-Sung Koo, Changwook Lee, Ki Bum Hong & Sungwook Choi. (2023) Novel Strategy To Inhibit Transthyretin Amyloidosis via the Synergetic Effect of Chemoselective Acylation and Noncovalent Inhibitor Release. Journal of Medicinal Chemistry 66:4, pages 2893-2903.
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Igor Sedov & Diliara Khaibrakhmanova. (2022) Molecular Mechanisms of Inhibition of Protein Amyloid Fibril Formation: Evidence and Perspectives Based on Kinetic Models. International Journal of Molecular Sciences 23:21, pages 13428.
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Tatum Prosswimmer & Valerie Daggett. (2022) The role of α-sheet structure in amyloidogenesis: characterization and implications. Open Biology 12:11.
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Lidia Ciccone, Nicolò Tonali, Carole Fruchart-Gaillard, Lucia Barlettani, Armando Rossello, Alessandra Braca, Elisabetta Orlandini & Susanna Nencetti. (2022) Antioxidant Quercetin 3-O-Glycosylated Plant Flavonols Contribute to Transthyretin Stabilization. Crystals 12:5, pages 638.
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Lidia Ciccone, Susanna Nencetti, Caterina Camodeca, Gabriella Ortore, Doretta Cuffaro, Simone Socci & Elisabetta Orlandini. (2022) Synthesis and Evaluation of Monoaryl Derivatives as Transthyretin Fibril Formation Inhibitors. Pharmaceutical Chemistry Journal 56:1, pages 38-47.
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Emily L. O'Reilly, Anita Horvatić, Josipa Kuleš, Andrea Gelemanović, Vladimir Mrljak, Yixin Huang, Nicola Brady, Christopher C. Chadwick, P. David Eckersall & Alison Ridyard. (2022) Faecal proteomics in the identification of biomarkers to differentiate canine chronic enteropathies. Journal of Proteomics 254, pages 104452.
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Fantao Sun, Jinsheng Liu, Yanan Huang, Xinyin Zhu, Yu Liu, Lei Zhang & Jinwu Yan. (2021) A quinoline derived D-A-D type fluorescent probe for sensing tetrameric transthyretin. Bioorganic & Medicinal Chemistry Letters 52, pages 128408.
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Lidia Ciccone, Nicolò Tonali, William Shepard, Susanna Nencetti & Elisabetta Orlandini. (2021) Physiological Metals Can Induce Conformational Changes in Transthyretin Structure: Neuroprotection or Misfolding Induction?. Crystals 11:4, pages 354.
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Ellen Y. Cotrina, Daniel Blasi, Marta Vilà, Antoni Planas, Cele Abad-Zapatero, Nuria B. Centeno, Jordi Quintana & Gemma Arsequell. (2020) Optimization of kinetic stabilizers of tetrameric transthyretin: A prospective ligand efficiency-guided approach. Bioorganic & Medicinal Chemistry 28:23, pages 115794.
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Natalia Zaręba & Marta Kepinska. (2020) The Function of Transthyretin Complexes with Metallothionein in Alzheimer’s Disease. International Journal of Molecular Sciences 21:23, pages 9003.
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Ellen Y. Cotrina, Ângela Oliveira, José Pedro Leite, Jordi Llop, Luis Gales, Jordi Quintana, Isabel Cardoso & Gemma Arsequell. (2020) Repurposing Benzbromarone for Familial Amyloid Polyneuropathy: A New Transthyretin Tetramer Stabilizer. International Journal of Molecular Sciences 21:19, pages 7166.
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