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Laboratory Studies

Nephroprotective Effect of Withania somnifera: A Dose-Dependent Study

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Pages 814-821 | Received 23 Feb 2009, Accepted 29 Jun 2009, Published online: 19 Nov 2009

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T. Jeyanthi, P. Subramanian, R. Sivaperumal & P. Kumaravel. (2014) Influence of Withania somnifera on 24 h oscillations of biomarkers in gentamicin induced nephrotoxicity. Biological Rhythm Research 45:2, pages 267-275.
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K.J Bibu, A.D Joy, MammenJ. Abraham & K.A Mercey. (2011) Evaluation of therapeutic effect of aqueous extract of stem bark of Mangifera indica Linn. on gentamicin-induced nephrotoxicity. Journal of Applied Animal Research 39:3, pages 252-256.
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Articles from other publishers (27)

Adrián Gómez Afonso, Diego Fernandez-Lazaro, David P. Adams, Aniol Monserdà-Vilaró & Cesar I. Fernandez-Lazaro. (2023) Effects of Withania somnifera (Ashwagandha) on Hematological and Biochemical Markers, Hormonal Behavior, and Oxidant Response in Healthy Adults: A Systematic Review. Current Nutrition Reports.
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Kristina August. 2023. Hospice and Palliative Care for Companion Animals. Hospice and Palliative Care for Companion Animals 265 277 .
Heba M. A. Khalil, Islam A. Khalil, Asmaa K. Al-Mokaddem, Marwa Hassan, Riham A. El-Shiekh, Hesham A. Eliwa, Azza M. Tawfek & Walaa H. El-Maadawy. (2022) Ashwagandha-loaded nanocapsules improved the behavioral alterations, and blocked MAPK and induced Nrf2 signaling pathways in a hepatic encephalopathy rat model. Drug Delivery and Translational Research 13:1, pages 252-274.
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Heba M. Salem, Mohamed T. El-Saadony, Taia A. Abd El-Mageed, Soliman M. Soliman, Asmaa F. Khafaga, Ahmed M. Saad, Ayman A. Swelum, Sameh A. Korma, Clara Mariana Gonçalves Lima, Samy Selim, Ahmad O. Babalghith, Mohamed E. Abd El-Hack, Fatima A. Omer, Synan F. AbuQamar, Khaled A. El-Tarabily & Carlos Adam Conte-Junior. (2022) Promising prospective effects of Withania somnifera on broiler performance and carcass characteristics: A comprehensive review. Frontiers in Veterinary Science 9.
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Welela Meka Kedir, Abebe Dukassa Dubiwak & Ebsa Tofik Ahmed. (2022) Nephroprotective Effect of Asparagus africanus Lam. Root Extract against Gentamicin-Induced Nephrotoxicity in Swiss Albino Mice. Journal of Toxicology 2022, pages 1-8.
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Pulok K Mukherjee, Thomas Efferth, Bhaskar Das, Amit Kar, Suparna Ghosh, Seha Singha, Pradip Debnath, Nanaocha Sharma, Pardeep Kumar Bhardwaj & Pallab Kanti Haldar. (2022) Role of medicinal plants in inhibiting SARS-CoV-2 and in the management of post-COVID-19 complications. Phytomedicine 98, pages 153930.
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Parakh Basist, Bushra Parveen, Sultan Zahiruddin, Gaurav Gautam, Rabea Parveen, Mohammad Ahmed Khan, Anuja Krishnan, Mohd Shahid & Sayeed Ahmad. (2022) Potential nephroprotective phytochemicals: Mechanism and future prospects. Journal of Ethnopharmacology 283, pages 114743.
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Pulok K. Mukherjee, Subhadip Banerjee, Sayan Biswas, Bhaskar Das, Amit Kar & C.K. Katiyar. (2021) Withania somnifera (L.) Dunal - Modern perspectives of an ancient Rasayana from Ayurveda. Journal of Ethnopharmacology 264, pages 113157.
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Vijay K. Bharti, Jitendra K. Malik & Ramesh C. Gupta. 2021. Nutraceuticals. Nutraceuticals 865 880 .
Renu Wadhwa, Sukant Garg, Mallika Khurana & Sunil C. Kaul. 2021. Nutrition, Food and Diet in Ageing and Longevity. Nutrition, Food and Diet in Ageing and Longevity 589 615 .
SmithaSyamala Vasavan, Vijayakumar Jagadesan, Senthilkumar Sivanesan & Vijayaraghavan Rajagopalan. (2020) Protective effect of Withania somnifera on nandrolone decanoate-induced biochemical alterations and hepatorenal toxicity in wistar rats. Pharmacognosy Magazine 16:68, pages 218.
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Shahid AkbarShahid Akbar. 2020. Handbook of 200 Medicinal Plants. Handbook of 200 Medicinal Plants 1933 1950 .
Prem Kumar Govindappa, Vidhi Gautam, Syamantak Mani Tripathi, Yash Pal Sahni & Hallur Lakshmana Shetty Raghavendra. (2019) Effect of Withania somnifera on gentamicin induced renal lesions in rats. Revista Brasileira de Farmacognosia 29:2, pages 234-240.
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Tamara Shearer & Kristina August. 2017. Hospice and Palliative Care for Companion Animals. Hospice and Palliative Care for Companion Animals 181 198 .
Vijay K. Bharti, Jitendra K. Malik & Ramesh C. Gupta. 2016. Nutraceuticals. Nutraceuticals 717 733 .
Elizabeth Grunz-Borgmann, Valeri Mossine, Kevin Fritsche & Alan R. Parrish. (2015) Ashwagandha attenuates TNF-α- and LPS-induced NF-κB activation and CCL2 and CCL5 gene expression in NRK-52E cells. BMC Complementary and Alternative Medicine 15:1.
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Sukhbir Kaur, Kalpana Chauhan & Heena Sachdeva. (2014) Protection against experimental visceral leishmaniasis by immunostimulation with herbal drugs derived from Withania somnifera and Asparagus racemosus. Journal of Medical Microbiology 63:10, pages 1328-1338.
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Ali A. El Gamal, Mansour S. AlSaid, Mohammad Raish, Mohammed Al-Sohaibani, Shaza M. Al-Massarani, Ajaz Ahmad, Mohamed Hefnawy, Mohammed Al-Yahya, Omer A. Basoudan & Syed Rafatullah. (2014) Beetroot ( Beta vulgaris L.) Extract Ameliorates Gentamicin-Induced Nephrotoxicity Associated Oxidative Stress, Inflammation, and Apoptosis in Rodent Model . Mediators of Inflammation 2014, pages 1-12.
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Biswa Mohan Biswal, Siti Amrah Sulaiman, Hasanah Che Ismail, Hasmat Zakaria & Kamarul Imran Musa. (2012) Effect of Withania somnifera (Ashwagandha) on the Development of Chemotherapy-Induced Fatigue and Quality of Life in Breast Cancer Patients . Integrative Cancer Therapies 12:4, pages 312-322.
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Heena Sachdeva, Rakesh Sehgal & Sukhbir Kaur. (2013) Studies on the protective and immunomodulatory efficacy of Withania somnifera along with cisplatin against experimental visceral leishmaniasis. Parasitology Research 112:6, pages 2269-2280.
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Tadiwos Feyissa, Kaleab Asres & Ephrem Engidawork. (2013) Renoprotective effects of the crude extract and solvent fractions of the leaves of Euclea divinorum Hierns against gentamicin-induced nephrotoxicity in rats. Journal of Ethnopharmacology 145:3, pages 758-766.
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R. Arora, J. Sharma, W. Selvamurthy, A.R. Shivashankara, N. Mathew & M.S. Baliga. 2013. Bioactive Food as Dietary Interventions for the Aging Population. Bioactive Food as Dietary Interventions for the Aging Population 305 320 .
Saleh Alqasoumi. (2011) Protective effect of Basella alba L. on nephrotoxicity induced by gentamycin in rats . Clinical and Experimental Medical Journal 5:4, pages 225-233.
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Badreldin H. Ali, Mohammed Al Za’abi, Gerald Blunden & Abderrahim Nemmar. (2011) Experimental Gentamicin Nephrotoxicity and Agents that Modify it: A Mini-Review of Recent Research. Basic & Clinical Pharmacology & Toxicology 109:4, pages 225-232.
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Arunachalam MUTHURAMAN, Sumeet Kumar SINGLA, Ajay RANA, Atinderjeet SINGH & Shailja SOOD. (2011) Reno-protective Role of Flunarizine (Mitochondrial Permeability Transition Pore Inactivator) against Gentamicin Induced Nephrotoxicity in Rats. YAKUGAKU ZASSHI 131:3, pages 437-443.
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Aaron R. Jex, Huw V. Smith, Matthew J. Nolan, Bronwyn E. Campbell, Neil D. Young, Cinzia Cantacessi & Robin B. Gasser. 2011. Advances in Parasitology Volume 77. Advances in Parasitology Volume 77 141 173 .

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