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Laboratory Study

Plasma Indoleamine 2,3-Dioxygenase Concentration is Increased in Hemodialysis Patients and May Contribute to the Pathogenesis of Coronary Heart Disease

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Pages 68-72 | Received 19 May 2011, Accepted 04 Sep 2011, Published online: 21 Oct 2011

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Read on this site (3)

Nigar Yilmaz, Yasemin Ustundag, Seyda Kivrak, Serdar Kahvecioglu, Huseyin Celik, Ibrahim Kivrak & Kağan Huysal. (2016) Serum indoleamine 2,3 dioxygenase and tryptophan and kynurenine ratio using the UPLC-MS/MS method, in patients undergoing peritoneal dialysis, hemodialysis, and kidney transplantation. Renal Failure 38:8, pages 1300-1309.
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Theodoros Eleftheriadis, Efi Yiannaki, Georgia Antoniadi, Vassilios Liakopoulos, Georgios Pissas, Grammati Galaktidou & Ioannis Stefanidis. (2012) Plasma Indoleamine 2,3-Dioxygenase and Arginase Type I May Contribute to Decreased Blood T-Cell Count in Hemodialysis Patients. Renal Failure 34:9, pages 1118-1122.
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Articles from other publishers (10)

Ananda Staats Pires, Shabarni Gupta, Sean A Barton, Roshana Vander Wall, Vanessa Tan, Benjamin Heng, Jacqueline K Phillips & Gilles J Guillemin. (2022) Temporal Profile of Kynurenine Pathway Metabolites in a Rodent Model of Autosomal Recessive Polycystic Kidney Disease. International Journal of Tryptophan Research 15, pages 117864692211260.
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Marta Marszalek-Grabska, Katarzyna Walczak, Kinga Gawel, Katarzyna Wicha-Komsta, Sylwia Wnorowska, Artur Wnorowski & Waldemar A. Turski. (2021) Kynurenine emerges from the shadows – Current knowledge on its fate and function. Pharmacology & Therapeutics 225, pages 107845.
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Alina Podkowińska & Dorota Formanowicz. (2020) Chronic Kidney Disease as Oxidative Stress- and Inflammatory-Mediated Cardiovascular Disease. Antioxidants 9:8, pages 752.
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Rongyi Chen, Jiachang Hu, Fangfang Xiang, Xiao Tan, Bo Shen, Zhonghua Liu, Wenlv Lv, Xiaoqiang Ding, Xuesen Cao & Jianzhou Zou. (2017) Decreased percentage of peripheral naïve T cells is independently associated with ischemic stroke in patients on hemodialysis. International Urology and Nephrology 49:11, pages 2051-2060.
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Yuanhan Chen, Zhen Xie, Chenggen Xiao, Min Zhang, Zhilian Li, Jianteng Xie, Yusheng Zhang, Xingchen Zhao, Pengfei Zeng, Liyi Mo, Xinling Liang & Wei Shi. (2017) Peripheral kynurenine/tryptophan ratio is not a reliable marker of systemic indoleamine 2,3-dioxygenase: A lesson drawn from patients on hemodialysis. Oncotarget 8:15, pages 25261-25269.
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Theodoros Eleftheriadis, Georgios Pissas, Maria Sounidaki, Georgia Antoniadi, Christos Rountas, Vassilios Liakopoulos & loannis Stefanidis. (2017) Tryptophan depletion under conditions that imitate insulin resistance enhances fatty acid oxidation and induces endothelial dysfunction through reactive oxygen species-dependent and independent pathways. Molecular and Cellular Biochemistry 428:1-2, pages 41-56.
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Min Ho Cha, Min Jung Kim, Jeeyoun Jung, Jin Hee Kim, Myeong Soo Lee & Myung-Sunny Kim. (2015) Metabolomic Analysis of Clinical Plasma from Cerebral Infarction Patients Presenting with Blood Stasis. Evidence-Based Complementary and Alternative Medicine 2015, pages 1-7.
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CHENGGEN XIAO, YUANHAN CHEN, XINLING LIANG, ZHEN XIE, MIN ZHANG, RUIZHAO LI, ZHILIAN LI, XIA FU, XIYONG YU & WEI SHI. (2014) A modified HPLC method improves the simultaneous determination of plasma kynurenine and tryptophan concentrations in patients following maintenance hemodialysis. Experimental and Therapeutic Medicine 7:4, pages 907-910.
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Asuka Tanaka, Akihiko Kato, Yuzo Suzuki, Masako Suzuki, Hiromitsu Ohmori, Ryo Sumimoto & Hideki Ohdan. (2014) Association of Increased Indoleamine 2, 3-Dioxygenase With Impaired Natural Killer Cell Activity in Hemodialysis Patients. Therapeutic Apheresis and Dialysis 18:1, pages 19-23.
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Kengo Ogawa, Takeshi Hara, Masahito Shimizu, Soranobu Ninomiya, Junji Nagano, Hiroyasu Sakai, Masato Hoshi, Hiroyasu Ito, Hisashi Tsurumi, Kuniaki Saito, Mitsuru Seishima, Takuji Tanaka & Hisataka Moriwaki. (2012) Suppression of azoxymethane-induced colonic preneoplastic lesions in rats by 1-methyltryptophan, an inhibitor of indoleamine 2,3-dioxygenase. Cancer Science 103:5, pages 951-958.
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