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Inhalation Toxicology
International Forum for Respiratory Research
Volume 25, 2013 - Issue 14
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Research Article

Estimating safe human exposure levels for lunar dust using benchmark dose modeling of data from inhalation studies in rats

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Pages 785-793 | Received 02 Aug 2013, Accepted 24 Sep 2013, Published online: 04 Dec 2013

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Chiu-wing Lam, Vincent Castranova, Patti C. Zeidler-Erdely, Roger Renne, Robert Hunter, Richard McCluskey, Robert R. Scully, William T. Wallace, Ye Zhang, Valerie E. Ryder, Bonnie Cooper, David McKay, Roger O. McClellan, Kevin E. Driscoll, Donald E. Gardner, Mark Barger, Terence Meighan & John T. James. (2022) Comparative pulmonary toxicities of lunar dusts and terrestrial dusts (TiO2 & SiO2) in rats and an assessment of the impact of particle-generated oxidants on the dusts’ toxicities. Inhalation Toxicology 34:3-4, pages 51-67.
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Articles from other publishers (15)

Christopher N. Nguyen & Emmanuel Urquieta. (2023) Contemporary review of dermatologic conditions in space flight and future implications for long-duration exploration missions. Life Sciences in Space Research 36, pages 147-156.
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Jon Rask. 2023. Encyclopedia of Lunar Science. Encyclopedia of Lunar Science 566 568 .
A. O. Pastukhov, N. V. Krisanova, O. O. Pylypchuk, N. G. Pozdnyakova, R. V. Sivko, A. G. Nazarova, L. M. Kalynovska & Т. O. Borisova. (2022) Development of neuroprotection approaches for long-term space missions. Kosmìčna nauka ì tehnologìâ 28:6, pages 52-62.
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Michael Pohlen, Danielle Carroll, G. Kim Prisk & Aenor J. Sawyer. (2022) Overview of lunar dust toxicity risk. npj Microgravity 8:1.
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Vladimir A. Barinov & Igor B. Ushakov. (2022) Toxicology of lunar dust in the aspect of possible occupational pathology of astronauts participating in an expedition to the Moon (review). Russian Journal of Occupational Health and Industrial Ecology 62:2, pages 72-90.
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Martin Braddock. 2021. The Human Factor in the Settlement of the Moon. The Human Factor in the Settlement of the Moon 141 157 .
Robert J. Reynolds. 2019. Lunar Science. Lunar Science.
Yan Sun, Lu Zhang, Jinguo Liu, Xiaoping Zhang, Yan Su, Quanling Yin & Shuangxi He. (2019) Effects of lunar dust simulant on cardiac function and fibrosis in rats. Toxicology Research 8:4, pages 499-508.
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Tatiana Borisova. (2019) Express assessment of neurotoxicity of particles of planetary and interstellar dust. npj Microgravity 5:1.
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John T. James & Valerie E. Ryder. 2019. Principles of Clinical Medicine for Space Flight. Principles of Clinical Medicine for Space Flight 153 174 .
Jon Rask. 2018. Encyclopedia of Lunar Science. Encyclopedia of Lunar Science 1 3 .
Jasmeet Kaur, Douglas Rickman & Martin A. Schoonen. (2016) Reactive Oxygen Species (ROS) generation by lunar simulants. Acta Astronautica 122, pages 196-208.
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John T. James. 2016. Space Physiology and Medicine. Space Physiology and Medicine 137 153 .
James T.F. WiseHong XieJohn Pierce WiseJr.Jr., Michael MasonAntony JeevarajanWilliam Wallace & John Pierce WiseSr.Sr.. (2015) Comparative Toxicity of Lunar, Martian Dust Simulants, and Urban Dust in Human Skin Fibroblast Cells. Gravitational and Space Research 3:1, pages 51-58.
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Chantal DarquenneMaria G. Borja, Jessica M. Oakes, Ellen C. BreenI. Mark OlfertMiriam Scadeng & G. Kim Prisk. (2014) Increase in relative deposition of fine particles in the rat lung periphery in the absence of gravity. Journal of Applied Physiology 117:8, pages 880-886.
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