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Articles

The biology and mechanism of action of suppressor of cytokine signaling 3

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Pages 207-219 | Received 02 Feb 2012, Accepted 18 Apr 2012, Published online: 11 May 2012

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Edmond M. Linossi, Dale J. Calleja & Sandra E. Nicholson. (2018) Understanding SOCS protein specificity. Growth Factors 36:3-4, pages 104-117.
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T Gui, BS He, Q Gan & C Yang. (2017) Enhanced SOCS3 in osteoarthiritis may limit both proliferation and inflammation. Biotechnic & Histochemistry 92:2, pages 107-114.
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R. Elkaim, I. M. Bugueno-Valdebenito, N. Benkirane-Jessel & H. Tenenbaum. (2017) Porphyromonas gingivalis and its lipopolysaccharide differently modulate epidermal growth factor–dependent signaling in human gingival epithelial cells. Journal of Oral Microbiology 9:1.
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Omar Ali, Diana Cerjak, Jack W. Kent$suffix/text()$suffix/text(), Roland James, John Blangero, Melanie A. Carless & Yi Zhang. (2016) Methylation of SOCS3 is inversely associated with metabolic syndrome in an epigenome-wide association study of obesity. Epigenetics 11:9, pages 699-707.
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Clara Degos, Aurélie Gagnaire, Romain Banchereau, Ignacio Moriyón & Jean-Pierre Gorvel. (2015) Brucella CβG induces a dual pro- and anti-inflammatory response leading to a transient neutrophil recruitment. Virulence 6:1, pages 19-28.
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Nadia J. Kershaw, Artem Laktyushin, Nicos A. Nicola & Jeffrey J. Babon. (2014) Reconstruction of an active SOCS3-based E3 ubiquitin ligase complex in vitro: identification of the active components and JAK2 and gp130 as substrates. Growth Factors 32:1, pages 1-10.
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Christine A White & Nicos A Nicola. (2013) SOCS3. JAK-STAT 2:4.
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Yong Tang & Xiuchun (Cindy) Tian. (2013) JAK-STAT3 and somatic cell reprogramming. JAK-STAT 2:4.
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Zhaoli Liu, Mariella Arcos, David R Martin & Xiang Xue. (2023) Myeloid FTH1 Deficiency Protects Mice From Colitis and Colitis-associated Colorectal Cancer via Reducing DMT1-Imported Iron and STAT3 Activation. Inflammatory Bowel Diseases 29:8, pages 1285-1296.
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Xueyan Li, Rong Hu, Haizhou Wang & Wen Xu. (2023) SOCS3 Silencing Promotes Activation of Vocal Fold Fibroblasts via JAK2/STAT3 Signaling Pathway. Inflammation 46:4, pages 1318-1331.
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Tadashi Matsuda. (2023) The Physiological and Pathophysiological Role of IL-6/STAT3-Mediated Signal Transduction and STAT3 Binding Partners in Therapeutic Applications. Biological and Pharmaceutical Bulletin 46:3, pages 364-378.
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Tao Li, Hong Ge, Qingyan Yang, Junmei Wang, Qian Yin, Hongbin Wang & Gaolei Hou. (2022) Oncogenic role of microRNA-19b-3p-mediated SOCS3 in glioma through activation of JAK-STAT pathway. Metabolic Brain Disease 38:3, pages 945-960.
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Xueyan Li, Rong Hu, Haizhou Wang & Wen Xu. (2022) Effect of SOCS3 on vocal fold fibroblast activation by regulating the JAK2/STAT3 signalling pathway. Tissue and Cell 79, pages 101965.
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Tsuyoshi Isojima, Emma C Walker, Ingrid J Poulton, Narelle E McGregor, Ian P Wicks, Jonathan H Gooi, T John Martin & Natalie A Sims. (2022) G‐CSF Receptor Deletion Amplifies Cortical Bone Dysfunction in Mice With STAT3 Hyperactivation in Osteocytes . Journal of Bone and Mineral Research 37:10, pages 1876-1890.
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Sungjin David Park, Apryl S. Saunders, Megan A. Reidy, Dawn E. Bender, Shari Clifton & Katherine T. Morris. (2022) A review of granulocyte colony-stimulating factor receptor signaling and regulation with implications for cancer. Frontiers in Oncology 12.
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Emira Bousoik, Parvin Mahdipoor, Abdulelah Alhazza & Hamidreza Montazeri Aliabadi. (2022) Combinational silencing of components involved in JAK/STAT signaling pathway. European Journal of Pharmaceutical Sciences 175, pages 106233.
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Chen Gao, Xiaolan Qi, Xin Gao, Jin Li, Yumin Qin, Yunjun Yin, Fei Gao, Tao Feng, Sen Wu & Xuguang Du. (2022) A Genome-Wide CRISPR Screen Identifies Factors Regulating Pluripotency Exit in Mouse Embryonic Stem Cells. Cells 11:15, pages 2289.
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Huailin Wang & Yan Fu. (2021) NR1D1 suppressed the growth of ovarian cancer by abrogating the JAK/STAT3 signaling pathway. BMC Cancer 21:1.
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Xiaohan Luan, Wenxian Yang, Xiaoyuan Bai, Heqiao Li, Huizi Li, Wenhui Fan, He Zhang, Wenjun Liu & Lei Sun. (2021) Cyclophilin A is a key positive and negative feedback regulator within interleukin‐6 trans‐signaling pathway. The FASEB Journal 35:11.
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Xinling Qian, Xiaotian Liu, Zhenxing Mao, Tanko Abdulai, Xiaokang Dong, Runqi Tu, Yan Wang, Xue Liu, Zhicheng Luo, Dou Qiao, Chongjian Wang & Yuqian Li. (2020) Fruit and vegetable intake modifies the associations between suppressor of cytokine signaling 3 genetic variants and type 2 diabetes. European Journal of Nutrition 59:8, pages 3441-3449.
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Wenjing Xu, Jingwei Fu, Hao Wu & Weijian Sun. (2018) Human epidermal growth factor receptor 2 expressions and Janus-activated kinase/signal transducer and activator of transcription 3-suppressor of cytokine signaling 3 pathway may be associated with clinicopathological features and prognosis of gastric cancer. Journal of Cancer Research and Therapeutics 14:Suppl 2, pages S311-S318.
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Snahlata Singh, Surbhi Chouhan, Naoshad Mohammad & Manoj Kumar Bhat. (2017) Resistin causes G1 arrest in colon cancer cells through upregulation of SOCS3. FEBS Letters 591:10, pages 1371-1382.
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Chang-ying Xing, De-xiang Zhang, Sui-qi Gui & Min-fang Tao. (2017) Kidney-Replenishing Herb Induces SOCS-3 Expression via ERK/MAPK Pathway and Improves Growth of the First-Trimester Human Trophoblast Cells. Evidence-Based Complementary and Alternative Medicine 2017, pages 1-12.
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R. Mahony, S. Ahmed, C. Diskin & N. J. Stevenson. (2016) SOCS3 revisited: a broad regulator of disease, now ready for therapeutic use?. Cellular and Molecular Life Sciences 73:17, pages 3323-3336.
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Vivianne B.C. Kokje, Gabor Gäbel, Dave Koole, Bernd H. Northoff, Lesca M. Holdt, Jaap F. Hamming & Jan H.N. Lindeman. (2016) IL-6: A Janus-like factor in abdominal aortic aneurysm disease. Atherosclerosis 251, pages 139-146.
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M. van de Vyver, C. Niesler, K.H. Myburgh & W.F. Ferris. (2016) Delayed wound healing and dysregulation of IL6/STAT3 signalling in MSCs derived from pre-diabetic obese mice. Molecular and Cellular Endocrinology 426, pages 1-10.
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Ling-Hsuan Wu, Chingju Lin, Hsiao-Yun Lin, Yu-Shu Liu, Caren Yu-Ju Wu, Cheng-Fang Tsai, Pei-Chun Chang, Wei-Lan Yeh & Dah-Yuu Lu. (2015) Naringenin Suppresses Neuroinflammatory Responses Through Inducing Suppressor of Cytokine Signaling 3 Expression. Molecular Neurobiology 53:2, pages 1080-1091.
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Bei-ge Jiang, Yuan Yang, Hui Liu, Fang-ming Gu, Yun Yang, Lin-Hao Zhao, Sheng-xian Yuan, Ruo-yu Wang, Jin Zhang & Wei-ping Zhou. (2015) SOCS3 Genetic Polymorphism Is Associated With Clinical Features and Prognosis of Hepatocellular Carcinoma Patients Receiving Hepatectomy. Medicine 94:40, pages e1344.
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X. Liu, R. Liu, B.A. Croker, K.E. Lawlor, G.K. Smyth & I.P. Wicks. (2015) Distinctive pro-inflammatory gene signatures induced in articular chondrocytes by oncostatin M and IL-6 are regulated by Suppressor of Cytokine Signaling-3. Osteoarthritis and Cartilage 23:10, pages 1743-1754.
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Chunguang Yan, Yanlan Liu, Hongwei Gao & Ximo Wang. (2015) Suppressors of cytokine signaling 3 is essential for FcγR-mediated inflammatory response via enhancing CCAAT/enhancer-binding protein δ transcriptional activity in macrophages. Experimental Cell Research 337:1, pages 120-127.
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Edmond M. Linossi & Sandra E. Nicholson. (2015) Kinase inhibition, competitive binding and proteasomal degradation: resolving the molecular function of the suppressor of cytokine signaling (SOCS) proteins. Immunological Reviews 266:1, pages 123-133.
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Xian Fu, Ligang Ren, Jing Chen, Kaisen Liao, Yu Fu, Xiaoyu Qian & Jiaquan Xiao. (2015) Characterization of the roles of suppressor of cytokine signaling-3 in prostate cancer development and progression. Asia-Pacific Journal of Clinical Oncology 11:2, pages 106-113.
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Christian Ehlting, Oliver Böhmer, Maximilian J. Hahnel, Maria Thomas, Ulrich M. Zanger, Matthias Gaestel, Wolfram T. Knoefel, Jan Schulte am Esch, Dieter Häussinger & Johannes G. Bode. (2015) Oncostatin M regulates SOCS3 mRNA stability via the MEK–ERK1/2-pathway independent of p38MAPK/MK2. Cellular Signalling 27:3, pages 555-567.
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Lidao Bao, Xudong Fu, Mingwen Si, Yi Wang, Ruilian Ma, Xianhua Ren & Haijun Lv. (2015) MicroRNA-185 Targets SOCS3 to Inhibit Beta-Cell Dysfunction in Diabetes. PLOS ONE 10:2, pages e0116067.
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Martin E. Rottenberg & Berit Carow. (2014) SOCS3 and STAT3, major controllers of the outcome of infection with Mycobacterium tuberculosis. Seminars in Immunology 26:6, pages 518-532.
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Amitabha Chaudhuri. (2014) Regulation of Macrophage Polarization by RON Receptor Tyrosine Kinase Signaling. Frontiers in Immunology 5.
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Dong Soon Choi, Elvin Blanco, Yoo-Shin Kim, Angel A. Rodriguez, Hong Zhao, Tim Hui-Ming Huang, Chun-Liang Chen, Guangxu Jin, Melissa D. Landis, Lacey A. Burey, Wei Qian, Sergio M. Granados, Bhuvanesh Dave, Helen H. Wong, Mauro Ferrari, Stephen T. C. Wong & Jenny C. Chang. (2014) Chloroquine Eliminates Cancer Stem Cells Through Deregulation of Jak2 and DNMT1. Stem Cells 32:9, pages 2309-2323.
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Xiao Liu, Ben A. Croker, Ian K. Campbell, Stephanie J. Gauci, Warren S. Alexander, Brett A. Tonkin, Nicole C. Walsh, Edmond M. Linossi, Sandra E. Nicholson, Kate E. Lawlor & Ian P. Wicks. (2014) Key Role of Suppressor of Cytokine Signaling 3 in Regulating gp130 Cytokine-Induced Signaling and Limiting Chondrocyte Responses During Murine Inflammatory Arthritis. Arthritis & Rheumatology 66:9, pages 2391-2402.
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Jeffrey J. Babon, Isabelle S. Lucet, James M. Murphy, Nicos A. Nicola & Leila N. Varghese. (2014) The molecular regulation of Janus kinase (JAK) activation. Biochemical Journal 462:1, pages 1-13.
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Kripa Patel, Anita Kollory, Asami Takashima, Sibaji Sarkar, Douglas V. Faller & Sajal K. Ghosh. (2014) MicroRNA let-7 downregulates STAT3 phosphorylation in pancreatic cancer cells by increasing SOCS3 expression. Cancer Letters 347:1, pages 54-64.
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