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Research Article

Endocrine and clinical effects of myo-inositol administration in polycystic ovary syndrome. A randomized study

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Pages 375-379 | Received 16 Oct 2012, Accepted 16 Oct 2012, Published online: 22 Jan 2013

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Oliver C. Watkins, Hannah E. J. Yong, Neha Sharma & Shiao-Yng Chan. (2022) A review of the role of inositols in conditions of insulin dysregulation and in uncomplicated and pathological pregnancy. Critical Reviews in Food Science and Nutrition 62:6, pages 1626-1673.
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Antonio Simone Laganà, Gianpiero Forte, Mariano Bizzarri, Zdravko A. Kamenov, Bianca Bianco, Cihan Kaya, Georgios Gitas, Ibrahim Alkatout, Milan Terzic & Vittorio Unfer. (2022) Inositols in the ovaries: activities and potential therapeutic applications. Expert Opinion on Drug Metabolism & Toxicology 18:2, pages 123-133.
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Giuseppe Derosa, Angela D’Angelo, Arianna Vanelli & Pamela Maffioli. (2020) An Evaluation of a Nutraceutical with Berberine, Curcumin, Inositol, Banaba and Chromium Picolinate in Patients with Fasting Dysglycemia. Diabetes, Metabolic Syndrome and Obesity 13, pages 653-661.
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Paolo Giovanni Artini, Maria Elena Rosa Obino, Elisabetta Micelli, Elisa Malacarne, Chiara Vacca, Francesca Papini & Vito Cela. (2020) Effect of d-chiro-inositol and alpha-lipoic acid combination on COH outcomes in overweight/obese PCOS women. Gynecological Endocrinology 36:9, pages 755-759.
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Fabio Facchinetti, Marialuisa Appetecchia, Cesare Aragona, Arturo Bevilacqua, Maria Salome Bezerra Espinola, Mariano Bizzarri, Rosario D’Anna, Didier Dewailly, Evanthia Diamanti-Kandarakis, Imelda Hernández Marín, Zdravko A. Kamenov, Eleni Kandaraki, Antonio Simone Laganà, Giovanni Monastra, Mario Montanino Oliva, John E. Nestler, Francesco Orio, Ali Cenk Ozay, Olga Papalou, Lali Pkhaladze, Giusy Porcaro, Nikos Prapas, Christophe O. Soulage, Annarita Stringaro, Artur Wdowiak & Vittorio Unfer. (2020) Experts’ opinion on inositols in treating polycystic ovary syndrome and non-insulin dependent diabetes mellitus: a further help for human reproduction and beyond. Expert Opinion on Drug Metabolism & Toxicology 16:3, pages 255-274.
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Elene Asanidze, Jenaro Kristesashvili, Lali Pkhaladze & Archil Khomasuridze. (2019) The value of anti-Mullerian hormone in the management of polycystic ovary syndrome in adolescents. Gynecological Endocrinology 35:11, pages 974-977.
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Anisha Agrawal, Reeta Mahey, Garima Kachhawa, Rajesh Khadgawat, Perumal Vanamail & Alka Kriplani. (2019) Comparison of metformin plus myoinositol vs metformin alone in PCOS women undergoing ovulation induction cycles: randomized controlled trial. Gynecological Endocrinology 35:6, pages 511-514.
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Maryam Shokrpour, Fatemeh Foroozanfard, Faraneh Afshar Ebrahimi, Zahra Vahedpoor, Esmat Aghadavod, Amir Ghaderi & Zatollah Asemi. (2019) Comparison of myo-inositol and metformin on glycemic control, lipid profiles, and gene expression related to insulin and lipid metabolism in women with polycystic ovary syndrome: a randomized controlled clinical trial. Gynecological Endocrinology 35:5, pages 406-411.
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Antoaneta Gateva, Vittorio Unfer & Zdravko Kamenov. (2018) The use of inositol(s) isomers in the management of polycystic ovary syndrome: a comprehensive review. Gynecological Endocrinology 34:7, pages 545-550.
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Paolo Giovanni Artini, Maria Elena Rosa Obino, Claudia Sergiampietri, Sara Pinelli, Francesca Papini, Elena Casarosa & Vito Cela. (2018) PCOS and pregnancy: a review of available therapies to improve the outcome of pregnancy in women with polycystic ovary syndrome. Expert Review of Endocrinology & Metabolism 13:2, pages 87-98.
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Özlen Emekçi Özay, Ali Cenk Özay, Erkan Çağlıyan, Recep Emre Okyay & Bülent Gülekli. (2017) Myo-inositol administration positively effects ovulation induction and intrauterine insemination in patients with polycystic ovary syndrome: a prospective, controlled, randomized trial. Gynecological Endocrinology 33:7, pages 524-528.
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Vittorio Unfer, Beatrice Orrù & Giovanni Monastra. (2016) Inositols: from physiology to rational therapy in gynecological clinical practice. Expert Opinion on Drug Metabolism & Toxicology 12:10, pages 1129-1131.
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Ewa M. Milewska, Adam Czyzyk, Blazej Meczekalski & Alessandro D. Genazzani. (2016) Inositol and human reproduction. From cellular metabolism to clinical use. Gynecological Endocrinology 32:9, pages 690-695.
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Cristiana Paul, Antonio Simone Laganà, Paolo Maniglio, Onofrio Triolo & David M. Brady. (2016) Inositol’s and other nutraceuticals’ synergistic actions counteract insulin resistance in polycystic ovarian syndrome and metabolic syndrome: state-of-the-art and future perspectives. Gynecological Endocrinology 32:6, pages 431-438.
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Zdravko Kamenov, Georgi Kolarov, Antoaneta Gateva, Gianfranco Carlomagno & Alessandro D. Genazzani. (2015) Ovulation induction with myo-inositol alone and in combination with clomiphene citrate in polycystic ovarian syndrome patients with insulin resistance. Gynecological Endocrinology 31:2, pages 131-135.
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