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Shuo Wang, Gang Li, Han Du & Jiling Feng. (2023) Low-dose radiation from CT examination induces DNA double-strand breaks and detectable changes of DNA methylation in peripheral blood cells. International Journal of Radiation Biology 0:0, pages 1-12.
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Simone Schüle, Carsten Hackenbroch, Meinrad Beer, Razan Muhtadi, Cornelius Hermann, Samantha Stewart, Daniel Schwanke, Patrick Ostheim, Matthias Port, Harry Scherthan & Michael Abend. (2023) Ex-vivo dose response characterization of the recently identified EDA2R gene after low level radiation exposures and comparison with FDXR gene expression and the γH2AX focus assay. International Journal of Radiation Biology 99:10, pages 1584-1594.
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Juan S. López, Mònica Pujol-Canadell, Pedro Puig, Gemma Armengol & Joan Francesc Barquinero. (2023) Evaluation of γ-H2AX foci distribution among different peripheral blood mononucleated cell subtypes. International Journal of Radiation Biology 99:10, pages 1550-1558.
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Juan S. López, Mònica Pujol-Canadell, Pedro Puig, Montserrat Ribas, Pablo Carrasco, Gemma Armengol & Joan F. Barquinero. (2022) Establishment and validation of surface model for biodosimetry based on γ-H2AX foci detection. International Journal of Radiation Biology 98:1, pages 1-10.
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Jayne Moquet, Stephen Barnard, Albena Staynova, Carita Lindholm, Octávia Monteiro Gil, Vanda Martins, Ute Rößler, Anne Vral, Charlot Vandevoorde, Maria Wojewódzka & Kai Rothkamm. (2017) The second gamma-H2AX assay inter-comparison exercise carried out in the framework of the European biodosimetry network (RENEB). International Journal of Radiation Biology 93:1, pages 58-64.
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Vinay Jain, P. A. Hassan & Birajalaxmi Das. (2014) Radiation-induced conformational changes in chromatin structure in resting human peripheral blood mononuclear cells. International Journal of Radiation Biology 90:12, pages 1143-1151.
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Veerle Vandersickel, Philip Beukes, Bram Van Bockstaele, Julie Depuydt, Anne Vral & Jacobus Slabbert. (2014) Induction and disappearance of γH2AX foci and formation of micronuclei after exposure of human lymphocytes to 60Co γ-rays and p(66)+ Be(40) neutrons. International Journal of Radiation Biology 90:2, pages 149-158.
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Julie Depuydt, Annelot Baert, Veerle Vandersickel, Hubert Thierens & Anne Vral. (2013) Relative biological effectiveness of mammography X-rays at the level of DNA and chromosomes in lymphocytes. International Journal of Radiation Biology 89:7, pages 532-538.
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Lenka Zárybnická, Jiřina Vávrová, Radim Havelek, Aleš Tichý, Jaroslav Pejchal & Zuzana Šinkorová. (2013) Lymphocyte subsets and their H2AX phosphorylation in response to in vivo irradiation in rats. International Journal of Radiation Biology 89:2, pages 110-117.
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Articles from other publishers (54)
Vinay Jain, Divyalakshmi Saini, D. C. Soren, V. Anil Kumar, P. R. Vivek Kumar, P. K. M. Koya, G. Jaikrishan & Birajalaxmi Das. (2023) Non-linear dose response of DNA double strand breaks in response to chronic low dose radiation in individuals from high level natural radiation areas of Kerala coast. Genes and Environment 45:1.
Crossref
Crossref
S. Schumann, H. Scherthan, K. Pfestroff, S. Schoof, A. Pfestroff, P. Hartrampf, N. Hasenauer, A. K. Buck, M. Luster, M. Port, M. Lassmann & U. Eberlein. (2021) DNA damage and repair in peripheral blood mononuclear cells after internal ex vivo irradiation of patient blood with 131I. European Journal of Nuclear Medicine and Molecular Imaging 49:5, pages 1447-1455.
Crossref
Crossref
Rujira Wanotayan, Sarinya Wongsanit, Kanokporn Boonsirichai, Kasama Sukapirom, Sakchai Buppaungkul, Putthiporn Charoenphun, Pucharee Songprakhon, Kulachart Jangpatarapongsa & Pimpon Uttayarat. (2022) Quantification of histone H2AX phosphorylation in white blood cells induced by ex vivo gamma irradiation of whole blood by both flow cytometry and foci counting as a dose estimation in rapid triage. PLOS ONE 17:3, pages e0265643.
Crossref
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An Aerts, Uta Eberlein, Sören Holm, Roland Hustinx, Mark Konijnenberg, Lidia Strigari, Fijs W.B. van Leeuwen, Gerhard Glatting & Michael Lassmann. (2021) EANM position paper on the role of radiobiology in nuclear medicine. European Journal of Nuclear Medicine and Molecular Imaging 48:11, pages 3365-3377.
Crossref
Crossref
Spyridon A. Kalospyros, Violeta Gika, Zacharenia Nikitaki, Antigoni Kalamara, Ioanna Kyriakou, Dimitris Emfietzoglou, Michael Kokkoris & Alexandros G. Georgakilas. (2021) Monte Carlo Simulation-Based Calculations of Complex DNA Damage for Incidents of Environmental Ionizing Radiation Exposure. Applied Sciences 11:19, pages 8985.
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Crossref
Katalin Lumniczky, Nathalie Impens, Gemma Armengol, Serge Candéias, Alexandros G. Georgakilas, Sabine Hornhardt, Olga A. Martin, Franz Rödel & Dörthe Schaue. (2021) Low dose ionizing radiation effects on the immune system. Environment International 149, pages 106212.
Crossref
Crossref
Qi Wang, Younghyun Lee, Monica Pujol-Canadell, Jay R. Perrier, Lubomir Smilenov, Andrew Harken, Guy Garty, David J. Brenner, Brian Ponnaiya & Helen C. Turner. (2021) Cytogenetic Damage of Human Lymphocytes in Humanized Mice Exposed to Neutrons and X Rays 24 h After Exposure. Cytogenetic and Genome Research 161:6-7, pages 352-361.
Crossref
Crossref
Venkateswarlu Raavi, Venkatachalam Perumal & Solomon F.D. Paul. (2021) Potential application of γ-H2AX as a biodosimetry tool for radiation triage. Mutation Research/Reviews in Mutation Research 787, pages 108350.
Crossref
Crossref
A. Giussani, M. A. Lopez, H. Romm, A. Testa, E. A. Ainsbury, M. Degteva, S. Della Monaca, G. Etherington, P. Fattibene, I. Güclu, A. Jaworska, D. C. Lloyd, I. Malátová, S. McComish, D. Melo, J. Osko, A. Rojo, S. Roch-Lefevre, L. Roy, E. Shishkina, N. Sotnik, S. Y. Tolmachev, A. Wieser, C. Woda & M. Youngman. (2020) Eurados review of retrospective dosimetry techniques for internal exposures to ionising radiation and their applications. Radiation and Environmental Biophysics 59:3, pages 357-387.
Crossref
Crossref
Jessica S. Helm & Ruthann A. Rudel. (2020) Adverse outcome pathways for ionizing radiation and breast cancer involve direct and indirect DNA damage, oxidative stress, inflammation, genomic instability, and interaction with hormonal regulation of the breast. Archives of Toxicology 94:5, pages 1511-1549.
Crossref
Crossref
Sarah Schumann, Harry Scherthan, Torsten Frank, Constantin Lapa, Jessica Müller, Simone Seifert, Michael Lassmann & Uta Eberlein. (2020) DNA Damage in Blood Leukocytes of Prostate Cancer Patients Undergoing PET/CT Examinations with [68Ga]Ga-PSMA I&T. Cancers 12:2, pages 388.
Crossref
Crossref
Younghyun Lee, Qi Wang, Igor Shuryak, David J. Brenner & Helen C. Turner. (2019) Development of a high-throughput γ-H2AX assay based on imaging flow cytometry. Radiation Oncology 14:1.
Crossref
Crossref
Shankari Nair, Monique Engelbrecht, Xanthene Miles, Roya Ndimba, Randall Fisher, Peter du Plessis, Julie Bolcaen, Jaime Nieto-Camero, Evan de Kock & Charlot Vandevoorde. (2019) The Impact of Dose Rate on DNA Double-Strand Break Formation and Repair in Human Lymphocytes Exposed to Fast Neutron Irradiation. International Journal of Molecular Sciences 20:21, pages 5350.
Crossref
Crossref
Stepan Ulyanenko, Margarita Pustovalova, Sergey Koryakin, Evgenii Beketov, Anatolii Lychagin, Liliya Ulyanenko, Andrey Kaprin, Anna Grekhova, Alexandra M. Ozerova, Ivan V. Ozerov, Natalia Vorobyeva, Peter Shegay, Sergey Ivanov, Sergey Leonov, Dmitry Klokov & Andreyan N. Osipov. (2019) Formation of γH2AX and pATM Foci in Human Mesenchymal Stem Cells Exposed to Low Dose-Rate Gamma-Radiation. International Journal of Molecular Sciences 20:11, pages 2645.
Crossref
Crossref
Priti Singh, Lalit Mohan Aggarwal, Stephen A Parry & Mercy J Raman. (2018) Radiation dosimetry and repair kinetics of DNA damage foci in mouse pachytene spermatocyte and round spermatid stages. Mutagenesis 33:3, pages 231-239.
Crossref
Crossref
Julie Depuydt, Tanguy Viaene, Phillip Blondeel, Nathalie Roche, Rudy Van den Broecke, Hubert Thierens & Anne Vral. (2018) DNA double strand breaks induced by low dose mammography X‑rays in breast tissue: A pilot study. Oncology Letters.
Crossref
Crossref
Vinay Jain, Divyalakshmi Saini, P.R. Vivek Kumar, G. Jaikrishan & Birajalaxmi Das. (2017) Efficient repair of DNA double strand breaks in individuals from high level natural radiation areas of Kerala coast, south-west India. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 806, pages 39-50.
Crossref
Crossref
Jennifer A. LemonNghi Phan & Douglas R. Boreham. (2017) Multiple CT Scans Extend Lifespan by Delaying Cancer Progression in Cancer-Prone Mice. Radiation Research 188:4.2, pages 495-504.
Crossref
Crossref
K. Zaleska, W.M. Suchorska, A. Kowalik, M. Kruszyna, W. Jackowiak, A. Skrobala, M. Skorska & J. Malicki. (2017) Low dose out-of-field radiotherapy, part 3: Qualitative and quantitative impact of scattered out-of-field radiation on MDA-MB-231 cell lines. Cancer/Radiothérapie 21:5, pages 358-364.
Crossref
Crossref
Roswitha Runge, Jana Arlt, Liane Oehme, Robert Freudenberg & Jörg Kotzerke. (2018) Comparison of clonogenic cell survival and DNA damage induced by 188Re and X-rays in rat thyroid cells. Nuklearmedizin 56:01, pages 47-54.
Crossref
Crossref
A Ivashkevich, T Ohnesorg, C E Sparbier & H Elsaleh. (2017) Advances in biological dosimetry. Journal of Physics: Conference Series 777, pages 012012.
Crossref
Crossref
Defang Ding, Yaping Zhang, Jing Wang, Xufei Wang, Dunhuang Fan, Linfeng He, Xuxia Zhang, Yun Gao, Qiang Li & Honghong Chen. (2016) γ-H2AX/53BP1/pKAP-1 foci and their linear tracks induced by in vitro exposure to radon and its progeny in human peripheral blood lymphocytes. Scientific Reports 6:1.
Crossref
Crossref
Janapriya Saha & Anthony J. Davis. (2016) Unsolved mystery: the role of BRCA1 in DNA end-joining. Journal of Radiation Research 57:S1, pages i18-i24.
Crossref
Crossref
Jing Wang, Lina Yin, Junxiang Zhang, Yaping Zhang, Xuxia Zhang, Defang Ding, Yun Gao, Qiang Li & Honghong Chen. (2016) The profiles of gamma-H2AX along with ATM/DNA-PKcs activation in the lymphocytes and granulocytes of rat and human blood exposed to gamma rays. Radiation and Environmental Biophysics 55:3, pages 359-370.
Crossref
Crossref
Jing Wang, Linfeng He, Dunhuang Fan, Defang Ding, Xufei Wang, Yun Gao, Xuxia Zhang, Qiang Li & Honghong Chen. (2016) Establishment of a γ-H2AX foci-based assay to determine biological dose of radon to red bone marrow in rats. Scientific Reports 6:1.
Crossref
Crossref
W. Rühm, T.V. Azizova, S.D. Bouffler, M.P. Little, R.E. Shore, L. Walsh & G.E. Woloschak. (2016) Dose-rate effects in radiation biology and radiation protection. Annals of the ICRP 45:1_suppl, pages 262-279.
Crossref
Crossref
Vinay Jain, P.R. Vivek Kumar, P.K.M. Koya, G. Jaikrishan & Birajalaxmi Das. (2016) Lack of increased DNA double-strand breaks in peripheral blood mononuclear cells of individuals from high level natural radiation areas of Kerala coast in India. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 788, pages 50-57.
Crossref
Crossref
Matus Durdik, Pavol Kosik, Jan Gursky, Lenka Vokalova, Eva Markova & Igor Belyaev. (2015) Imaging flow cytometry as a sensitive tool to detect low-dose-induced DNA damage by analyzing 53BP1 and γH2AX foci in human lymphocytes. Cytometry Part A 87:12, pages 1070-1078.
Crossref
Crossref
Muriel Viau, Isabelle Testard, Grace Shim, Luc Morat, Marie D. Normil, William M. Hempel & Laure Sabatier. (2015) Global quantification of γH2AX as a triage tool for the rapid estimation of received dose in the event of accidental radiation exposure. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 793, pages 123-131.
Crossref
Crossref
Werner Rühm, Gayle E. Woloschak, Roy E. Shore, Tamara V. Azizova, Bernd Grosche, Ohtsura Niwa, Suminori Akiba, Tetsuya Ono, Keiji Suzuki, Toshiyasu Iwasaki, Nobuhiko Ban, Michiaki Kai, Christopher H. Clement, Simon Bouffler, Hideki Toma & Nobuyuki Hamada. (2015) Dose and dose-rate effects of ionizing radiation: a discussion in the light of radiological protection. Radiation and Environmental Biophysics 54:4, pages 379-401.
Crossref
Crossref
Uta Eberlein, Carina Nowak, Christina Bluemel, Andreas Konrad Buck, Rudolf Alexander Werner, Harry Scherthan & Michael Lassmann. (2015) DNA damage in blood lymphocytes in patients after 177Lu peptide receptor radionuclide therapy. European Journal of Nuclear Medicine and Molecular Imaging 42:11, pages 1739-1749.
Crossref
Crossref
Uta Eberlein, Michel Peper, Maria Fernández, Michael Lassmann & Harry Scherthan. (2015) Calibration of the γ-H2AX DNA Double Strand Break Focus Assay for Internal Radiation Exposure of Blood Lymphocytes. PLOS ONE 10:4, pages e0123174.
Crossref
Crossref
Felix Zwicker, Benedict Swartman, Falk Roeder, Florian Sterzing, Henrik Hauswald, Christian Thieke, Klaus-Josef Weber, Peter E. Huber, Kai Schubert, Jürgen Debus & Klaus Herfarth. (2015) In vivo measurement of dose distribution in patients' lymphocytes: helical tomotherapy versus step-and-shoot IMRT in prostate cancer. Journal of Radiation Research 56:2, pages 239-247.
Crossref
Crossref
C. Vandevoorde, C. Franck, K. Bacher, L. Breysem, M. H. Smet, C. Ernst, A. De Backer, K. Van De Moortele, P. Smeets & H. Thierens. (2014) γ-H2AX foci as in vivo effect biomarker in children emphasize the importance to minimize x-ray doses in paediatric CT imaging. European Radiology 25:3, pages 800-811.
Crossref
Crossref
Caitlin E. Mills, Christopher Thome, David Koff, David W. Andrews & Douglas R. Boreham. (2015) The Relative Biological Effectiveness of Low-Dose Mammography Quality X Rays in the Human Breast MCF-10A Cell Line. Radiation Research 183:1, pages 42-51.
Crossref
Crossref
Martin Large, Sebastian Reichert, Stephanie Hehlgans, Claudia Fournier, Claus Rödel & Franz Rödel. (2014) A non-linear detection of phospho-histone H2AX in EA.hy926 endothelial cells following low-dose X-irradiation is modulated by reactive oxygen species. Radiation Oncology 9:1.
Crossref
Crossref
Yuan-Wei Liang, Junsheng Zheng, Xiaoling Li, Wenjie Zheng & Tianfeng Chen. (2014) Selenadiazole derivatives as potent thioredoxin reductase inhibitors that enhance the radiosensitivity of cancer cells. European Journal of Medicinal Chemistry 84, pages 335-342.
Crossref
Crossref
Tiziana Cervelli, Daniele Panetta, Teresa Navarra, Maria Grazia Andreassi, Giuseppina Basta, Alvaro Galli, Piero A. Salvadori, Eugenio Picano & Serena Del Turco. (2014) Effects of single and fractionated low-dose irradiation on vascular endothelial cells. Atherosclerosis 235:2, pages 510-518.
Crossref
Crossref
Nitya N. Srivastava, Sandeep K. Shukla, M.H. Yashavarddhan, Memita Devi, Rajendra P. Tripathi & Manju L. Gupta. (2014)
Modification of radiation-induced DNA double strand break repair pathways by chemicals extracted from
Podophyllum hexandrum
: An in vitro study in human blood leukocytes
. Environmental and Molecular Mutagenesis 55:5, pages 436-448.
Crossref
Crossref
Bregje van Oorschot, Suzanne E. Hovingh, Perry D. Moerland, Jan Paul Medema, Lukas J.A. Stalpers, Harry Vrieling & Nicolaas A.P. Franken. (2014) Reduced Activity of Double-Strand Break Repair Genes in Prostate Cancer Patients With Late Normal Tissue Radiation Toxicity. International Journal of Radiation Oncology*Biology*Physics 88:3, pages 664-670.
Crossref
Crossref
Andreas Lamkowski, Fabien Forcheron, Diane Agay, Emad A. Ahmed, Michel Drouet, Viktor Meineke & Harry Scherthan. (2014) DNA Damage Focus Analysis in Blood Samples of Minipigs Reveals Acute Partial Body Irradiation. PLoS ONE 9:2, pages e87458.
Crossref
Crossref
Kai Rothkamm, Stephen Barnard, Elizabeth A. Ainsbury, Jenna Al-hafidh, Joan-Francesc Barquinero, Carita Lindholm, Jayne Moquet, Marjo Perälä, Sandrine Roch-Lefèvre, Harry Scherthan, Hubert Thierens, Anne Vral & Veerle Vandersickel. (2013) Manual versus automated γ-H2AX foci analysis across five European laboratories: Can this assay be used for rapid biodosimetry in a large scale radiation accident?. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 756:1-2, pages 170-173.
Crossref
Crossref
K. Rothkamm, S. Horn, H. Scherthan, U. Rößler, A. De Amicis, S. Barnard, Ulrike Kulka, F. Lista, V. Meineke, H. Braselmann, C. Beinke & M. Abend. (2013) Laboratory Intercomparison on the γ-H2AX Foci Assay. Radiation Research 180:2, pages 149.
Crossref
Crossref
BREGJE VAN OORSCHOT, SUZANNE E. HOVINGH, HANS RODERMOND, AHMED GÜÇLÜ, NIENKE LOSEKOOT, ALBERT A. GELDOF, GERRIT W. BARENDSEN, LUKAS J. STALPERS & NICOLAAS A.P. FRANKEN. (2013) Decay of γ-H2AX foci correlates with potentially lethal damage repair in prostate cancer cells. Oncology Reports 29:6, pages 2175-2180.
Crossref
Crossref
Joke Werbrouck, Piet Ost, Valerie Fonteyne, Gert De Meerleer, Wilfried De Neve, Evelien Bogaert, Laurence Beels, Klaus Bacher, Anne Vral & Hubert Thierens. (2013) Early biomarkers related to secondary primary cancer risk in radiotherapy treated prostate cancer patients: IMRT versus IMAT. Radiotherapy and Oncology 107:3, pages 377-381.
Crossref
Crossref
Stephen Barnard, Simon Bouffler & Kai Rothkamm. (2013) The shape of the radiation dose response for DNA double-strand break induction and repair. Genome Integrity 4:1, pages 1.
Crossref
Crossref
Eileen Pernot, Janet Hall, Sarah Baatout, Mohammed Abderrafi Benotmane, Eric Blanchardon, Simon Bouffler, Houssein El Saghire, Maria Gomolka, Anne Guertler, Mats Harms-Ringdahl, Penny Jeggo, Michaela Kreuzer, Dominique Laurier, Carita Lindholm, Radhia Mkacher, Roel Quintens, Kai Rothkamm, Laure Sabatier, Soile Tapio, Florent de Vathaire & Elisabeth Cardis. (2012) Ionizing radiation biomarkers for potential use in epidemiological studies. Mutation Research/Reviews in Mutation Research 751:2, pages 258-286.
Crossref
Crossref
Laurence Beels, Klaus Bacher, Peter Smeets, Koenraad Verstraete, Anne Vral & Hubert Thierens. (2012) Dose-length product of scanners correlates with DNA damage in patients undergoing contrast CT. European Journal of Radiology 81:7, pages 1495-1499.
Crossref
Crossref
Felix Zwicker, Benedict Swartman, Florian Sterzing, Gerald Major, Klaus-Josef Weber, Peter E Huber, Christian Thieke, Jürgen Debus & Klaus Herfarth. (2011) Biological in-vivo measurement of dose distribution in patients' lymphocytes by gamma-H2AX immunofluorescence staining: 3D conformal- vs. step-and-shoot IMRT of the prostate gland. Radiation Oncology 6:1.
Crossref
Crossref
Nathan T. Martin, Shareef A. Nahas, Rashmi Tunuguntla, Francesca Fike & Richard A. Gatti. (2011) Assessing ‘radiosensitivity’ with kinetic profiles of γ-H2AX, 53BP1 and BRCA1 foci. Radiotherapy and Oncology 101:1, pages 35-38.
Crossref
Crossref
Simon Horn, Stephen Barnard & Kai Rothkamm. (2011) Gamma-H2AX-Based Dose Estimation for Whole and Partial Body Radiation Exposure. PLoS ONE 6:9, pages e25113.
Crossref
Crossref
Tania Mandina, Sandrine H. Roch-Lefèvre, Pascale Voisin, Jorge E. González, Ana I. Lamadrid, Ivonne Romero, Omar García, Philippe Voisin & Laurence Roy. (2011) Dose-response relationship of γ-H2AX foci induction in human lymphocytes after X-rays exposure. Radiation Measurements 46:9, pages 997-999.
Crossref
Crossref
M. Valente, P. Voisin, P. Laloi, L. Roy & S. Roch-Lefèvre. (2011) Automated gamma-H2AX focus scoring method for human lymphocytes after ionizing radiation exposure. Radiation Measurements 46:9, pages 871-876.
Crossref
Crossref
Denis V. Firsanov, Liudmila V. Solovjeva & Maria P. Svetlova. (2011) H2AX phosphorylation at the sites of DNA double-strand breaks in cultivated mammalian cells and tissues. Clinical Epigenetics 2:2, pages 283-297.
Crossref
Crossref